RSC – Anal. Methods latest articles- Comparative Study on Selective Profiling of Cardiovascular and Cerebrovascular Disease-Associated Proteins Using Two Statin-Based Magnetic Separation Materials September 9, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D5AY01174D, PaperYanfeng Zheng, Yini Pan, Zhenxin Wang, Zhichao Yan, Lingyi Zhang, Weibing ZhangThis study established a drug-associated protein screening strategy leveraging the principle of specific protein-drug interactions. Two first-line lipid-lowering drugs, atorvastatin (AN) and rosuvastatin (RSV), were covalently immobilized onto nanoparticle surface...The content of this RSS Feed (c) The Royal […]Yanfeng Zheng
- An aptasensor-based fluorescent signal amplification strategy for highly sensitive detection of mycotoxins September 9, 2025Anal. Methods, 2025, Advance ArticleDOI: 10.1039/D5AY01100K, PaperYingjuan Qu, Xingyu He, Feng Li, Yunhui Zhai, Peng LiuA novel report on the design of an aptamer sensor utilizing a fluorescence signal amplification strategy for the highly sensitive detection of mycotoxins (aflatoxin B1, ochratoxin A, and fumonisin B1).To cite this article before page numbers are assigned, use the […]Yingjuan Qu
- Dual-responsive colorimetric and ‘turn on’ fluorometric probes for the rapid detection of Cu2+ and F ‾ ions: Crystal structure, spectral elucidation, smartphone-based colorimetric readout, and applications in bio-imaging of zebrafish larvae September 8, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D5AY01091H, PaperGajendhiran Ramalingam, Abbas Khaja Raees Ahmed, Sivaraj Mithra, Abdul S Majeed, Sahul A.S. Hameed, S. Jegadheeshwari, M. Kesavan, M. Nizammohideen, A. Kalilur RahimanIn this work, we report two dual-responsive colorimetric and ‘turn-on’ fluorometric probe molecules 1,5-bis(4-isopropylbenzylidene)carbohydrazone (S1) and 1,5-bis(4-isopropylbenzylidene)thiocarbohydrazone (S2) for the rapid detection of biologically significant inorganic ions. […]Gajendhiran Ramalingam
- Electrochemical Aptasensing Strategies for Emerging Organic Pollutants in Environmental Analysis September 8, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D5AY01084E, Critical ReviewAnyou Xie, Weihong Wu, Meiqing JinEmerging organic pollutants (EOPs), encompassing a vast array of substances like pharmaceuticals, pesticides, endocrine disruptors, and industrial chemicals, pose a significant threat to environmental integrity and human health. Traditional analytical...The content of this RSS Feed (c) The Royal Society of ChemistryAnyou Xie
- Porous Microneedle-Based Electrochemical Sensor for Potassium and Glucose in Skin Interstitial Fluid September 7, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D5AY00915D, PaperDake Ai, Xin Tang, Zhenlong Meng, Yang Yu, Xiuxiu guo, Yuanpeng WangThe monitoring of biomarkers in interstitial fluid (ISF) holds significant promise for non-invasive, real-time health assessment. In this study, we present a novel porous microneedle-based electrochemical sensor (PMES) designed for...The content of this RSS Feed (c) The Royal […]Dake Ai
- Assessment of the metabolic stability of avapritinib in human liver microsomes using a fast and green UPLC-MS/MS method: screening for structural alarms associated with metabolic lability and in silico toxicity September 7, 2025Anal. Methods, 2025, Advance ArticleDOI: 10.1039/D5AY01035G, PaperMohamed W. Attwa, Ali S. Abdelhameed, Haitham AlRabiah, Adnan A. KadiAn UPLC-MS/MS method was established for assessing avapritinib in HLMs matrix. In silico analysis suggests that minor structural changes to the methyl pyrazole moiety in drug design may improve the metabolic stability relative to avapritinib.To cite this article before […]Mohamed W. Attwa
- Structurally tailored Rh-Au heterodimers: plasmon-boosted oxidase mimetics for facile tea authentication via colorimetric sensing September 7, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D5AY01236H, PaperKaixin Song, Xueqing Sang, Yanying Zheng, Jinfang Nie, Yun Zhang, Wenxin Niu, Yali YuanWhile nanozymes show remarkable potential in colorimetric sensing, conventional systems often suffer from compromised sensitivity and operational complexity in complex analytical scenarios. Herein, a novel heterostructured nanozyme by integrating Au...The content of this RSS Feed (c) […]Kaixin Song
- Amplified electrochemical detection of sulfadiazine based on Cu-BTC-encapsulated FeNi dual-atom catalysts with improved catalytic efficiency September 7, 2025Anal. Methods, 2025, Advance ArticleDOI: 10.1039/D5AY01036E, PaperShuhuai Li, Yinian Zhu, Xionghui Ma, Chaohai Pang, Rui Chen, Zongqiang ZhuA sensitive electrochemical sensor for sulfadiazine detection was developed using Cu-BTC@FeNi–SAs for signal amplification and a MIP for recognition. It offers high selectivity among sulfonamides and resistance to ionic interference.To cite this article before page numbers are assigned, […]Shuhuai Li
- Enhanced detection of N-Acetylneuraminic acid using a chemiluminescence enzyme-linked immunosorbent assay September 7, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D5AY01350J, CommunicationAbdurrahman Usman, Yaojun Zhu, Murtala Isah Bindawa, Xiaoying ZhangN-acetylneuraminic Acid (Neu5Ac) is a key sialic acid in food and food products that influences nutritional quality, glycosylation, and microbial interactions. Neu5Ac is integral to cellular recognition, immune modulation, neural...The content of this RSS Feed (c) The Royal Society of ChemistryAbdurrahman Usman
- Liquid-phase microextraction method for the separation of hexavalent and total chromium in environmental water samples with spectrophotometric detection September 4, 2025Anal. Methods, 2025, Advance ArticleDOI: 10.1039/D5AY01075F, PaperZekeriyya Bahadır, Demet TasmacıoğluMetal pollution, particularly chromium, in water and food samples is a critical issue due to its transfer to the human body through the food chain and its threat to human health.To cite this article before page numbers are assigned, use the DOI form of citation above.The […]Zekeriyya Bahadır
- Development of a Smartphone-Based Colorimetric Chemosensor for On-Site Detection of Indium Ions in Environmental Water Samples: Solution and Solid-State Analysis September 4, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D5AY01214G, PaperSavikriti Saini, Selva Kumar Ramasamy, Vetriarasu VenkatesanA novel diaminomaleonitrile-based colorimetric probe, 2-amino-3-[(8-hydroxy-2-quinolinyl)methylene]amino]-2-butenedinitrile (HQ-DAMN), was successfully synthesized and extensively characterized using a range of spectroscopic techniques. The sensing ability of HQ-DAMN towards multiple cations was investigated using...The content of this RSS Feed (c) The Royal Society of ChemistrySavikriti Saini
- A thorough LC-MS/MS strategy to quantify abaloparatide in rat plasma: method development, validation and application September 3, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D5AY01189B, PaperYing Kong, Xiangping Li, Yan Li, Yuan Tan, Tongfang Li, Yani Xiao, Li Zhang, Qinglong Yu, Rong RongBackground: Abaloparatide is a newly approved analog of parathyroid hormone-related peptide. It is used for the treatment of osteoporosis in postmenopausal women who have a high risk of fracture. The...The content of […]Ying Kong
- A modified QuEChERS method for simultaneous determination of 73 pesticides, 23 PCBs and 16 PAHs in wheat by GC-MS/MS September 3, 2025Anal. Methods, 2025, Advance ArticleDOI: 10.1039/D5AY00950B, PaperMengmeng Yan, Yujie Xie, Mengjie Shi, Xingqiang Wu, Kaixuan Tong, Qiaoying Chang, Hui ChenIn this study, a modified QuEChERS method for the simultaneous determination of 73 pesticides, 23 PCBs and 16 PAHs in wheat was developed by gas chromatography-triple quadrupole tandem mass spectrometry (GC-MS/MS).To cite this article before page […]Mengmeng Yan
- Research on egg yolk color detection based on near infrared spectroscopy and machine vision September 3, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D5AY01039J, PaperYukuan Wen, Guimei Dong, Weijian Yin, Renjie Yang, Liuan Li, Xiaoxue Yu, Yuan Li, Yaping YuYolk color is a key indicator of egg quality, as customers prefer eggs with intensely yellow yolks, which also signal nutrient richness. At present, the commonly used method of yolk...The content of this RSS […]Yukuan Wen
- Development of a Waterlily-Inspired Autonomous Cloud Connected Platform for Ca²⁺ Monitoring September 2, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D5AY01095K, Paperismail ağırIn this study, we developed an innovative water quality monitoring platform that enables cloud-based data transmission using a calcium ion-selective electrode. On-field measurement systems offer significant advantages for water quality...The content of this RSS Feed (c) The Royal Society of Chemistryismail ağır
- Lower critical solution temperature-responsive deep eutectic solvent: A novel tool for triazole fungicides residue analysis in environmental water samples September 2, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D5AY01159K, PaperXuerong Yang, Yu Wang, Linqi Shen, Xiaoyan Jiang, Panfei Li, Jinsong Liu, Zu-Guang LiSwitchable deep eutectic solvents have attracted increasing attention from researchers due to their unique characteristics of responding to the external environment. In this experiment, a series of temperature-responsive deep eutectic...The content of this RSS Feed (c) […]Xuerong Yang
- Ecofriendly Densitometric (RP and NP) HPTLC Methods for Determination of Sorafenib in bulk and formulation September 2, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D5AY01031D, CommunicationPratiksha Bang, Hardik Girishkumar BhattThe growing demand for sustainable analytical practices has emphasized the need for green methodologies in pharmaceutical analysis. Anticancer drugs require precise and efficient quality control due to their therapeutic significance...The content of this RSS Feed (c) The Royal Society of ChemistryPratiksha Bang
- Quantitative profiling of lipid mediators in sperm cells through on-line dilution on-line polymer matrix based solid phase extraction liquid chromatography with mass spectrometric detection September 2, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D5AY00250H, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Jörg Fabian, Matthias LehrAn automated on-line dilution on-line solid-phase extraction liquid chromatography-mass spectrometry method was developed for the straightforward and versatile quantitative profiling of lipid mediators such as various eicosanoids, endocannabinoids, and arachidonic...The content […]Jörg Fabian
- pH-gated bidirectional nanoassembly switches: self-ratiometric D-penicillamine sensing via AIE-active Au(I)-TCEP-Cd(II) coordination dynamics September 2, 2025Anal. Methods, 2025, Advance ArticleDOI: 10.1039/D5AY00899A, PaperKunyang Li, Yelan Xiao, Yafang Sun, Zhi He, Jiarong Tian, Lei Su, Xueji Zhang, Tong ShuA pH-gated bidirectional sensing platform was fabricated based on aggregation induced emission-active Au(I)-tris(2-carboxyethyl)phosphine nanoaggregates by the stoichiometric introduction of Cd2+ for highly reliable D-penicillamine detection.To cite this article before page numbers are assigned, use […]Kunyang Li
- Ambient liquid extraction-mass spectrometry for studying release kinetics of flavor components from tipping papers to oral saliva September 1, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D5AY00903K, PaperWeiWei Wei, Qinke Li, Ru Ma, Yuqi Cui, S. Ding, Yu Zhao, Qian Wu, Zhiguo WangA quantitative ambient liquid extraction-mass spectrometry method for flavor components on cigarette tipping paper was developed and utilized to quantify their release kinetics from tipping paper into the oral saliva...The content of this RSS […]WeiWei Wei
- Comparative Study on Selective Profiling of Cardiovascular and Cerebrovascular Disease-Associated Proteins Using Two Statin-Based Magnetic Separation Materials September 9, 2025
