RSC – Anal. Methods latest articles- Synergistic non-covalent-recognition-enabled highly efficient through-space charge transfer for specific synthetic cannabinoid EG-2201 detection April 23, 2026Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D6AY00189K, PaperLiwei Tang, Chuanfang Zhao, Jiahao Dong, Turghun Muhammad, Jiajia Fan, Xincun Dou, Yuan LiuA new fluorescent probe was developed upon a multiple non-covalent recognition for EG-2201, eliciting a sensitive response via highly efficient TSCT. By combining the probe with an intelligent device, the precise detection of EG-2201 was achieved.To […]Liwei Tang
- Poly-thymine-mediated fluorescence recovery of N-CQDs for turn-on sensing of APE1 activity in breast cancer cell lysates April 23, 2026Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D6AY00468G, PaperXinjuan Xiong, Yanning Li, Minghui Zhao, Juan Zhao, Shulong Xiong, Zhao SunA label-free turn-on fluorescent biosensor is developed for APE1 activity detection based on APE1-gated release of poly-T strands from a constrained DNA duplex, which competitively displaces Ag+ from N-CQDs, recovering fluorescence.To cite this article before page numbers are […]Xinjuan Xiong
- Adaptive spectral band optimization for low-cost multispectral estimation of maize leaf chlorophyll using a LASSO–IARO strategy April 23, 2026Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D6AY00404K, PaperFu Zhang, Zifei Yang, Baoping Yan, Fangyuan Zhang, Yakun Zhang, Yafei Wang, Sanling FuEffective estimation of maize leaf chlorophyll content using spectroscopic techniques.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of ChemistryFu Zhang
- Specific detection of Hg2+ based on a ZnO/C dual-quantum-dot system April 23, 2026Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D6AY00049E, PaperDongdong Li, Meijia Cui, Zhenjiang Li, Yao Lu, Zhuwei Zhang, Wei Huang, Qiaoling Jing, Hao Cheng, Jun Feng, Wenyi HuangSchematic of a fluorescence sensor for the specific detection of Hg2+ based on a ZnO/C dual-quantum-dot system.To cite this article before page numbers are assigned, use the DOI form of […]Dongdong Li
- Post-synthetic and in situ engineering of metal nanoclusters for enhanced stability and multifunctional applications April 22, 2026Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D6AY00154H, Critical ReviewRitika Mittal, Nancy GuptaEngineering metal nanoclusters via post-synthetic and in situ strategies enhances stability and photoluminescence while enabling new functionalities. This review critically evaluates these approaches, associated properties, and applications.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this […]Ritika Mittal
- Capillary-SERS Sensor Based on Aptamer-Mediated Inhibition of Nanozyme Catalysis for Ultrasensitive Detection of Homocysteine in Serum from Hepatocellular Carcinoma Patients April 22, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00151C, PaperWangxuan Xia, Juncheng Shi, Yongjin Yu, Ming Tan, Lin Xia, Chun DaiEarly detection and sensitive monitoring of homocysteine (Hcy) in serum are crucial for liver cancer screening. Here, we developed a capillary-based SERS sensor utilizing aptamer capture of Hcy and the...The content of this RSS Feed (c) The Royal […]Wangxuan Xia
- A highly sensitive SERS sensor for malachite green detection based on spiky Fe3O4@Au supraparticles April 22, 2026Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D6AY00166A, PaperHang Ye, Yanke Wang, Hufu Chen, Tao Huang, Shengnan ZhanA novel label-free analytical strategy based on surface-enhanced Raman spectroscopy (SERS) has been developed for the detection of malachite green (MG) using spiky Fe3O4@Au supraparticles (Fe3O4@AuSPs).To cite this article before page numbers are assigned, use the DOI form of citation […]Hang Ye
- Unveiling the geographical signature of black tea through UHPLC-Quadrupole-Orbitrap Exploris HRMS analysis April 21, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00096G, PaperSubodh Kumar BUDAKOTI, Khalid Anwar, Narendra K Nagendla, Anirudh Bhat M L, Dasharath P Oulkar, Pratibha SharmaAbstract Understanding the geographical differentiation of black tea is essential for exploring the influence of territory on its chemical composition. In this study, black tea (powder) samples from key tea-producing...The content of this […]Subodh Kumar BUDAKOTI
- On-line Gas Diffusion Membrane Separation-Flow Injection Analysis with Spectrophotometric Detection for Automated Determination of Ammonia Nitrogen in Complex Industrial Wastewater April 21, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00656F, PaperJun Hu, Rui Huang, Peng Li, Yanli Hua, Kunde LinDetermination of ammonia nitrogen (NH 3 -N) in industrial wastewater is often challenged by complex matrix interference, and traditional laboratory analysis cannot provide timely feedback for dynamic process regulation. To...The content of this RSS Feed (c) The Royal Society of […]Jun Hu
- Hydrogen-bond enhanced Tb/Eu-MOF for visual detection of multiple trace fluoroquinolones in seawater and a portable 3D-printed sensor April 21, 2026Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D6AY00082G, PaperZheng Chen, Shuaibo Song, Jiahao Lu, Simin Wang, Shuo Chen, Zhong Han, Fang YuanA salt-resistant dual-lanthanide MOF (Tb/Eu-BTC@BTEC) constructed via hydrogen-bond network enhancement enables rapid on-site visual sensing of fluoroquinolones in marine environments.To cite this article before page numbers are assigned, use the DOI form of citation above.The content […]Zheng Chen
- Development and validation of an LC-MS/MS/MS method for the sensitive quantification of trace β-agonists in complex animal-derived food matrices April 21, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00363J, PaperChujun Liu, Jiankang Ren, Qian Ran, Yuliang Xu, Boyan Sun, Zhiyue Feng, Sihan Wang, Jie Xie, Haiyang JiangConventional multiple reaction monitoring (MRM) quantification of β-agonists in complex matrices was hindered by insufficient sensitivity due to co-extracted matrix interferences. To address this drawback, we developed a highly selective...The content of […]Chujun Liu
- A Portable Near-Infrared Aptasensor Platform for Derivatization-Assisted On-Site Analysis of Acrylamide in Food Samples April 21, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00267F, PaperLingli Bu, Meixing Liu, Qihang Yang, Xinkai Li, Minglei Li, Luyao Li, Song Wang, Sheng Lei, Jiaheng ZhangRapid and reliable on-site analysis remains a central challenge in food safety monitoring, particularly for small-molecule contaminants that are difficult to detect using portable analytical platforms. Acrylamide (AM), a typical...The content of […]Lingli Bu
- Electrochemically Amplified Nanozymatic Activity of Biolinker-based Synthesized Co-MOF for H 2 O 2 and Dopamine Detection April 21, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00361C, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jasmine Look, Syed Rahin Ahmed, Mohamed Hassan Mahana, Md Shalauddin, Shamima Akhter, Wan Jeffrey Basirun, Seshasai Srinivasan, Amin Reza RajabzadehRapid, sensitive and selective H 2 O 2 & dopamine sensors provide enormous opportunities to […]Jasmine Look
- A Ratiometric Fluorescence Sensor Based on Bifunctional Cu-MOF Nanozyme for Dual-Signal Detection of Glyphosate in Actual Samples April 20, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00220J, PaperYubo Zhang, Liu Chao, Huihui Ge, Tianyi Zheng, Wang Jianhua, Yaoyong WangThis study proposes a glyphosate (GLY) detection strategy based on metal-organic framework (MOF) nanozymes, achieved by synthesizing copper-based MOF nanozyme (Cu-MOF) via a one-pot hydrothermal method and integrating them into...The content of this RSS Feed (c) The Royal […]Yubo Zhang
- Self-Amplifying Cascade Strategy Triggered Au NPs Assembly for Ultrasensitive cTnI Detection with Dynamic Light Scattering April 20, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00491A, PaperLiansheng Ling, chen chen, Yingqing Li, xiaosong Yang, Ji ZhangHere we report an ultrasensitive dynamic light scattering (DLS) immunosensor for cardiac troponin I (cTnI) leveraging a novel Self-cascading reaction synergistic amplification strategy by using metal organic frameworks (MOF) materials....The content of this RSS Feed (c) The Royal Society of […]Liansheng Ling
- Engineering a Nanobody-Alkaline Phosphatase Bifunctional Probe for Enhanced Immunoassay Performance toward Microcystin-LR April 20, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00556J, PaperYingying Ma, Tong Ai, Xingyi Chen, Rui Zhang, Ruoyu Li, Hanlin Jin, Yurun Pei, Peng Liu, Jie Luo, Qi ChenEutrophication caused by excessive nutrient discharge has led to the frequent occurrence of cyanobacterial blooms, during which toxic metabolites such as microcystins (MCs) are released into aquatic environments. Among these,...The […]Yingying Ma
- An Al3+ Ions-Responsive Blue Emitting Ionic Liquid-Based Nano-Optode and Its Implications for the Detection of 2, 4, 6-Trinitrophenol April 20, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00179C, PaperSubham Lama, Sudhir Kumar DasThis report introduces a novel IL-mediated fluorescence turn-on photoluminescence nanooptode designed for the highly sensitive and selective monitoring of aluminium ions (Al³⁺).The fabricated nano-optode exhibited pronounced optical responsiveness to Al³⁺...The content of this RSS Feed (c) The Royal Society of ChemistrySubham Lama
- Preparation of MIL-68@Fe₃O₄@PVDF Composites via Spray Phase Inversion Method and Their Magnetic Solid-Phase Extraction of Parabens and Bisphenol A April 20, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00276E, PaperXinwen Hu, Yong Zhang, Zhihao Chen, Mengqian Xiao, Litao Wang, Guihua GaoIn this study, the spray phase inversion method was employed for the first time to prepare MIL-68@Fe3O4@PVDF. The preparation process involved dispersing Fe3O4 in a PVDF/DMF solution; when the Fe3O4-loaded...The content of this RSS Feed (c) The Royal […]Xinwen Hu
- A Dot-Array Magnetic Enrichment Strategy for Rapid, Multiplexed Detection of Viable Bacteria via ATP Bioluminescence April 20, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00153J, Paperchunyan Zhang, Chengjian Chen, Weifei Zhang, Jiayu Zheng, Tuya Wulan, Xuanlin Feng, Zhisheng Wu, Nan LiThe sensitive detection of microorganisms in complex samples, such as herbal medicines, was significantly hampered by severe matrix interference and low target abundance. While magnetic separation and microfluidics offered enrichment...The content of this RSS […]chunyan Zhang
- Development and validation of QbD-Integrated sensitive RP-HPLC method for quantitation of Fenofibrate: An application in quality control April 20, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01843A, PaperRomi Singh, Abhiram Kumar, Ashutosh Pareek, Dipti Srivastava, Madhaw Kumar, Mohini Chaurasia, Swaran FloraAim: The present study aims to develop and validate a robust, sensitive HPLC method for the estimation of fenofibrate in a gel-matrix sustained-release tablet formulation designed to prevent alcohol-induced Dose...The content of this RSS Feed (c) […]Romi Singh
- Synergistic non-covalent-recognition-enabled highly efficient through-space charge transfer for specific synthetic cannabinoid EG-2201 detection April 23, 2026
