Nano silver – Disinfectant alternative to Chloramine B

Disinfectant spray

1.      Chloramine B.

Chloramine B is a common antibacterial agent used to disinfect surfaces, water and air.

Some information about Chloramine B

IUPAC name: sodium benzene sulfonyl (chlorine) azanide.

Other name: Sodium N-chlorobenzenesulfonamide

Molecular formula: C6H5ClNNaO2S
Color: White powder
Odor: smell of chlorine
Molecular Weight: 213.62
Melting point: 170-173°C
Solubility: soluble in water, ethanol, sparingly soluble in ether, chloroform
H302 (97.56%): Harmful if swallowed [ Warning Acute toxicity, by mouth] H314 (95.12%): Causes serious skin burns and eye damage [ Danger Corrosion / skin irritation] H334 (97.56%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [ Sensitive hazard, respiratory]

Advantages of Chloramine B

A broad-spectrum, fast-acting germicide thanks to active chlorine or Cl+ ions strong oxidizing properties
The price of chloramin B 25% is usually cheap (40,000 – 300,000 VND / kg) depending on the quantity
Concentrations of Chloramine B 25% are used to kill bacteria as low as 0.5% to 1.25%.

Disadvantages of Chloramine B

May be harmful to eyes, skin and respiratory system
Kills bacteria, viruses and fungi quickly, but also loses its effect quickly
Has an unpleasant smell of chlorine. For a closed space without an exhaust fan system, it is very difficult to deal with all the odors.
When spraying leaves a thin white powder on the surface. Produce fine dust that affects user’s health

2. Nano Silver

Nano silver are silver nanoparticles with a nanometer size (1-100 nm). Silver nanoparticles are antibacterial by releasing Ag+ ions, silver particles at the nanoscale 1-10nm can directly affect the bacterial cell membrane by changing the osmotic pressure. lead to cell death

(Nano silver bactericidal mechanism)

Some information about nano silver

IUPAC Name: Silver
Molecular Formula: Ag
CAS Number: 7440-22-4
Molecular Weight: 868
Color: At a large size silver is a silver solid, at nanometer size, silver nanoparticles absorbs light in the visible region of 400-450 nm, so when at 10 ppm nano silver has a lemon yellow color. The higher the concentration, the darker the color


Broad spectrum against bacteria, viruses and fungi
Silver particles adhere to the surface so that the bactericidal effect lasts up to 48 hours
No unpleasant smell
Nano silver is a safe bactericide that does not cause skin, eye or respiratory irritation

(LD50 CaCO3 is 6500 mg/kg and silver is 5000 mg/kg body weight, indicating the safety of nano silver)


If you buy Chloramine B in bulk a few hundred kilograms or more, the cost of nano silver is higher than Chloramine B. If you buy in small quantities, the cost can be much cheaper than Chloramine B by 25%.
Time to kill bacteria, viruses, fungi is slower than Chloramin B.
The antibacterial effect of 30 ppm nano silver after 1 minute is more than 95%

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