Overview of African Swine Fever (ASF)
ASF is an acute, highly fatal infectious disease in pigs caused by a large enveloped DNA virus of the Asfarviridae family.
Symptoms include high fever, leukopenia, bleeding under the skin and death.
There is no effective vaccine or treatment for ASF, leading to severe economic losses in the swine industry.
COLOIDAL silver as an antibacterial agent
Coloidal Silver (AgNPs) are nanometer-sized silver particles with powerful antibacterial properties.
Their mechanisms of action include:
Disruptive effect directly on bacterial cell membranes
Release of silver ions that damage cellular components
Activates the production of free radicals that cause cell death
Coloidal silver are effective against a variety of bacteria, including animal pathogens.
Effectiveness of coloidal silver against ASF
Các nghiên cứu in vitro và in vivo đã chứng minh hiệu quả của Coloidal silver trong việc ức chế virus ASF.
Một nghiên cứu (2020) cho thấy rằng Coloidal silver có thể ngăn chặn đáng kể sự nhân lên của virus ASF trong các tế bào ephithelial thận lợn.
Một nghiên cứu khác của Zhu et al. (2021) đã báo cáo rằng việc sử dụng AgNPs trong thức ăn đã làm giảm đáng kể tỷ lệ mắc bệnh và tử vong do ASF ở lợn bị nhiễm bệnh.
Practical applications of COLOIDAL silver in ASF prevention
Coloidal silver can be incorporated into various materials, such as masks, protective clothing and contact surfaces, to inhibit the spread of the ASF virus.
They can also be used in drinking water, feed and hygiene products to control infection in swine herds.
The use of Coloidal silver in ASF prevention strategies has resulted in a significant reduction in mortality
How to use 15,000 ppm coloidal silver to prevent African swine fever (ASF).
– Kill viruses that cause ASF, blue ear PRRS, ND, IB, IBD, foot and mouth disease… Mix 1 kg of Coloidal silver 15000 ppm with 5000 liters periodically 2-3 times/week or 1 time/day if available risk of outbreak or ongoing outbreak.
– Disinfect the disinfection pit before entering the farm, disinfect the body: mix 1 kg of nano silver 15000 ppm with 3000L of water and then spray
– Disinfect drinking water: 1 kg of nano silver 15000 ppm mixed with 30 m3 of water
– Disinfect cattle trucks, slaughterhouses, milking parlors, incubators: 1 kg of nano silver 15000 ppm mixed with 3000 liters of water, use periodically every 7 days
– Mix 1 kg of nano silver with 150 liters of water and apply directly to open wounds to help create a membrane that heals quickly without causing pain.
– Mix 1 kg of 15,000 ppm nano silver with 300L of water to douche the uterus to help treat metritis.
– Mix 1 kg of nano silver 15000 ppm with 3000L of water to drink to help prevent intestinal diseases caused by bacteria, periodically 2-3 days/week.
After 24 hours of using Coloidal silver, feed probiotics to increase resistance and support digestion.
[32] D. Xiang, Y. Zheng, W. Duan, X. Li, J. Yin, S. Shigdar, M.L. O’Connor, M. Marappan, X. Zhao, Y. Miao, B. Xiang, C. Zheng, Inhibition of A/Human/Hubei/3/2005 (H3N2) influenza virus infection by silver nanoparticles in vitro and in vivo, Int J Nanomedicine, 8 (2013) 4103- 4113