RSC – Anal. Methods latest articles- Development and validation of an LC-MS/MS/MS method for the sensitive quantification of trace β-agonists in complex animal-derived food matrices April 21, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00363J, PaperChujun Liu, Jiankang Ren, Qian Ran, Yuliang Xu, Boyan Sun, Zhiyue Feng, Sihan Wang, Jie Xie, Haiyang JiangConventional multiple reaction monitoring (MRM) quantification of β-agonists in complex matrices was hindered by insufficient sensitivity due to co-extracted matrix interferences. To address this drawback, we developed a highly selective...The content of […]Chujun Liu
- A Portable Near-Infrared Aptasensor Platform for Derivatization-Assisted On-Site Analysis of Acrylamide in Food Samples April 21, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00267F, PaperLingli Bu, Meixing Liu, Qihang Yang, Xinkai Li, Minglei Li, Luyao Li, Song Wang, Sheng Lei, Jiaheng ZhangRapid and reliable on-site analysis remains a central challenge in food safety monitoring, particularly for small-molecule contaminants that are difficult to detect using portable analytical platforms. Acrylamide (AM), a typical...The content of […]Lingli Bu
- Hydrogen-bond enhanced Tb/Eu-MOF for visual detection of multiple trace fluoroquinolones in seawater and a portable 3D-printed sensor April 21, 2026Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D6AY00082G, PaperZheng Chen, Shuaibo Song, Jiahao Lu, Simin Wang, Shuo Chen, Zhong Han, Fang YuanA salt-resistant dual-lanthanide MOF (Tb/Eu-BTC@BTEC) constructed via hydrogen-bond network enhancement enables rapid on-site visual sensing of fluoroquinolones in marine environments.To cite this article before page numbers are assigned, use the DOI form of citation above.The content […]Zheng Chen
- On-line Gas Diffusion Membrane Separation-Flow Injection Analysis with Spectrophotometric Detection for Automated Determination of Ammonia Nitrogen in Complex Industrial Wastewater April 21, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00656F, PaperJun Hu, Rui Huang, Peng Li, Yanli Hua, Kunde LinDetermination of ammonia nitrogen (NH 3 -N) in industrial wastewater is often challenged by complex matrix interference, and traditional laboratory analysis cannot provide timely feedback for dynamic process regulation. To...The content of this RSS Feed (c) The Royal Society of […]Jun Hu
- Unveiling the geographical signature of black tea through UHPLC-Quadrupole-Orbitrap Exploris HRMS analysis April 21, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00096G, PaperSubodh Kumar BUDAKOTI, Khalid Anwar, Narendra K Nagendla, Anirudh Bhat M L, Dasharath P Oulkar, Pratibha SharmaAbstract Understanding the geographical differentiation of black tea is essential for exploring the influence of territory on its chemical composition. In this study, black tea (powder) samples from key tea-producing...The content of this […]Subodh Kumar BUDAKOTI
- A Ligation DNAzyme-Driven Catalytic Hairpin Assembly Strategy for miRNA Detection April 20, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00460A, PaperHongbo Zhang, Yugang Xiao, Zhuoer Zeng, Di Zhang, Zhirui Song, xiaoke wu, Qubo ZhuMicroRNAs (miRNAs) are emerging biomarkers for clinical diagnosis, yet their short length, low abundance, and sequence similarity pose substantial challenges for reliable detection. Here, we propose a ligation DNAzyme with...The content of this RSS Feed (c) […]Hongbo Zhang
- Preparation of MIL-68@Fe₃O₄@PVDF Composites via Spray Phase Inversion Method and Their Magnetic Solid-Phase Extraction of Parabens and Bisphenol A April 20, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00276E, PaperXinwen Hu, Yong Zhang, Zhihao Chen, Mengqian Xiao, Litao Wang, Guihua GaoIn this study, the spray phase inversion method was employed for the first time to prepare MIL-68@Fe3O4@PVDF. The preparation process involved dispersing Fe3O4 in a PVDF/DMF solution; when the Fe3O4-loaded...The content of this RSS Feed (c) The Royal […]Xinwen Hu
- An Al3+ Ions-Responsive Blue Emitting Ionic Liquid-Based Nano-Optode and Its Implications for the Detection of 2, 4, 6-Trinitrophenol April 20, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00179C, PaperSubham Lama, Sudhir Kumar DasThis report introduces a novel IL-mediated fluorescence turn-on photoluminescence nanooptode designed for the highly sensitive and selective monitoring of aluminium ions (Al³⁺).The fabricated nano-optode exhibited pronounced optical responsiveness to Al³⁺...The content of this RSS Feed (c) The Royal Society of ChemistrySubham Lama
- Development and validation of QbD-Integrated sensitive RP-HPLC method for quantitation of Fenofibrate: An application in quality control April 20, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01843A, PaperRomi Singh, Abhiram Kumar, Ashutosh Pareek, Dipti Srivastava, Madhaw Kumar, Mohini Chaurasia, Swaran FloraAim: The present study aims to develop and validate a robust, sensitive HPLC method for the estimation of fenofibrate in a gel-matrix sustained-release tablet formulation designed to prevent alcohol-induced Dose...The content of this RSS Feed (c) […]Romi Singh
- Engineering a Nanobody-Alkaline Phosphatase Bifunctional Probe for Enhanced Immunoassay Performance toward Microcystin-LR April 20, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00556J, PaperYingying Ma, Tong Ai, Xingyi Chen, Rui Zhang, Ruoyu Li, Hanlin Jin, Yurun Pei, Peng Liu, Jie Luo, Qi ChenEutrophication caused by excessive nutrient discharge has led to the frequent occurrence of cyanobacterial blooms, during which toxic metabolites such as microcystins (MCs) are released into aquatic environments. Among these,...The […]Yingying Ma
- Self-Amplifying Cascade Strategy Triggered Au NPs Assembly for Ultrasensitive cTnI Detection with Dynamic Light Scattering April 20, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00491A, PaperLiansheng Ling, chen chen, Yingqing Li, xiaosong Yang, Ji ZhangHere we report an ultrasensitive dynamic light scattering (DLS) immunosensor for cardiac troponin I (cTnI) leveraging a novel Self-cascading reaction synergistic amplification strategy by using metal organic frameworks (MOF) materials....The content of this RSS Feed (c) The Royal Society of […]Liansheng Ling
- A ratiometric fluorescence/colorimetric dual-response sensor based on fluorescent nanozymes and smartphone-assisted for accurate determination of glyphosate residues April 20, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00379F, PaperXuhai Ding, Ying Zhang, tao Bo, Jinhua Zhang, Wenyan Yan, Baoqing Bai, Yu-Kun YangIn this study, a ratio-fluorescence/colorimetric sensor based on copper-based metal-organic framework nanozymes (Cu-BH) was developed for detection of organophosphorus pesticides (OPs). The sensor utilized the intrinsic fluorescence properties of the...The content of this RSS Feed (c) […]Xuhai Ding
- A Dot-Array Magnetic Enrichment Strategy for Rapid, Multiplexed Detection of Viable Bacteria via ATP Bioluminescence April 20, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00153J, Paperchunyan Zhang, Chengjian Chen, Weifei Zhang, Jiayu Zheng, Tuya Wulan, Xuanlin Feng, Zhisheng Wu, Nan LiThe sensitive detection of microorganisms in complex samples, such as herbal medicines, was significantly hampered by severe matrix interference and low target abundance. While magnetic separation and microfluidics offered enrichment...The content of this RSS […]chunyan Zhang
- A Ratiometric Fluorescence Sensor Based on Bifunctional Cu-MOF Nanozyme for Dual-Signal Detection of Glyphosate in Actual Samples April 20, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00220J, PaperYubo Zhang, Liu Chao, Huihui Ge, Tianyi Zheng, Wang Jianhua, Yaoyong WangThis study proposes a glyphosate (GLY) detection strategy based on metal-organic framework (MOF) nanozymes, achieved by synthesizing copper-based MOF nanozyme (Cu-MOF) via a one-pot hydrothermal method and integrating them into...The content of this RSS Feed (c) The Royal […]Yubo Zhang
- Integration of a Screening-Guided Near-Infrared Aptasensor into a Portable Platform for Quantitative On-Site Detection of N¹-Methyladenosine April 19, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00228E, PaperQi Pang, Dandan Zhang, Ruilin Ma, Wuduo Zhao, Xinyue Cao, Zhongyang Huang, Tuanjie Huang, Jiaheng ZhangN¹-Methyladenosine (m¹A) is an important RNA modification associated with diverse biological processes and disease states, yet rapid and quantitative on-site detection of m¹A remains challenging. Herein, we report a near-infrared...The content of this RSS […]Qi Pang
- Analytical characterization of bulk R-Salt and its odor profile to establish a framework for canine detection April 19, 2026Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D6AY00077K, PaperJanet Crespo-Cajigas, Melissa J. Clinard, Shawanda Roberts, Dawn M. MillsTD-GC-MS was used to characterize the headspace of an improvised explosive, R-Salt. This study provides foundational data and methodology that is essential for the development and validation of canine training aids and field vapor sampling devices.To cite this article before […]Janet Crespo-Cajigas
- Highly sensitive identification of illegal cooking oil by surface-enhanced Raman spectroscopy combined with acyl nucleophilic substitution reaction to detect capsaicin April 16, 2026Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D6AY00465B, PaperShengping Han, Guican Deng, Yonghua Bao, Yanping Hong, Jiaxin Hong, Luying Duan, Huaying Du, Zhimei Tan, Chunrong WangA simple method for capsaicin detection based on acyl nucleophilic substitution coupled with surface-enhanced Raman spectroscopy has been developed for the rapid screening and identification of gutter oil adulteration.To cite this article […]Shengping Han
- Zirconium and vanadium bimetallic organic framework nanozyme for bioenzymes-free colorimetric and photothermal dual-mode direct detection of organophosphorus pesticides April 16, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00494F, PaperChenxu Wang, Ningjing Du, Zhe You, Yinhui Yi, Gangbing ZhuPresently, the vast majority of colorimetric methods for the detection of organophosphorus pesticides (OPs) generally require the presence of bioenzymes coupled with just single-signal mode. Herein, by using VCl3 and...The content of this RSS Feed (c) The Royal Society of […]Chenxu Wang
- Development and Prospects of Fluorescence Polarization Immunoassay for Pesticide Detection in Food and Environment April 16, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00409A, Critical ReviewWeiguo Yu, Zhenjiang LiuThe excessive and improper application of pesticides severely jeopardizes ecological balance and poses a serious threat to human health. Fluorescence polarization immunoassay (FPIA) is a homogeneous immunoassay technique that offers...The content of this RSS Feed (c) The Royal Society of ChemistryWeiguo Yu
- Ratiometric fluorescence determination of Gd(III) using plumbagin: method validation and analysis of real samples April 15, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00311G, PaperNhan Tam Do, Le Thi Thanh Tran, Nguyen Le Anh, Pham Van Tat, Van Tan LeIn this research, the spectroscopic interaction between plumbagin (PLB) and Gd(III) was studied using UV-Vis, fluorescence techniques. When Gd(III) coordinated with PLB, clear spectral changes were found, together with the...The content of this RSS […]Nhan Tam Do
- Development and validation of an LC-MS/MS/MS method for the sensitive quantification of trace β-agonists in complex animal-derived food matrices April 21, 2026
