RSC – Food Funct. latest articles- Anti-inflammatory activity of orange peel aqueous extract and hesperidin : Integrated evidence from neutrophil assays, in vivo models, and in silico analyses June 14, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D6FO00864J, PaperTinhinane Rekeb, Samia Bedouhene, Nassima Senani, Sahra Amel Belambri, Meriem- Dehbia Chabane, R Ksouri, My-Chan Pham, Jamel El BennaCitrus peels have traditionally been used for their anti-inflammatory properties. Their bioactive compounds can modulate neutrophil activation and reduce ROS production, both of which play key roles in the development...The content […]Tinhinane Rekeb
- Alleviating effects of 2′-fucosyllactose combined with Bifidobacterium longum BB536 on loperamide-induced constipation and depressive-like behavior June 14, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D6FO00474A, PaperZhongmei Tan, Zihao Tian, Xiaolei Duan, He Zhang, Wei Yu, Qinggang Xie, Dong Xu, Yingying Ding, Rongbiao Ying, Jiage Ma, Qiqi RenThis study evaluated the effects and underlying mechanism of 2′-fucosyllactose and Bifidobacterium longum BB536 on relieving loperamide-induced constipation and depressive-like behavior.To cite this article before page numbers are […]Zhongmei Tan
- The hawthorn (Crataegus pinnatifida) procyanidin extract attenuates nonalcoholic fatty liver disease in mice via remodeling the bile acid profile driven by gut microbiota and regulating the FXR pathway June 14, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D6FO01304J, PaperXue Han, Yuchen Fang, Huanyu Wang, Anni Fu, Jianfeng Sun, Zhiqiang Wang, Lei MaHawthorn procyanidin extract (HPC) is one of natural plant-derived polyphenol with lipid-lowering and liver-protective properties, while its therapeutic mechanisms against nonalcoholic fatty liver disease (NAFLD) require further clarification.To cite this article before page numbers are assigned, […]Xue Han
- Taurine supplementation at the crossroads of metabolism, inflammation and aging: mechanistic and nutritional perspectives June 14, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D6FO01808D, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Benedikt Justus Beine, Melissa Castellano, Jarlei Fiamoncini, Karsten HillerTaurine, the most abundant free amino acid in mammals, supports mitochondrial function and regulates inflammation. Supplementation can improve metabolic health and promote healthy aging, highlighting […]Benedikt Justus Beine
- Protective Efficacy and Related Mechanism of a new ADH Activating Peptide YRPG from Lactococcus lactis Against Acute Alcohol-Induced Injury June 11, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D6FO01977C, PaperAnran Feng, Beijie Li, Sisi Chen, Shiyu Zhao, Zhangning Qiao, Yanling Shi, Laizheng Lu, Juan juan Yi, Jike LuExcessive alcohol intake can cause severe acute alcohol injury (AAI). Alcohol dehydrogenase (ADH)-activating peptide is an effective means to alleviate this injury. This study investigated the protective effects of the...The content […]Anran Feng
- Integrating sustainability and nutrition: comprehensive valorisation of vegetable by-products for bioactive food applications June 11, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D6FO00309E, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Tatiane C De Oliveira, Tayse F.F. da Silveria, Dejan Stojkovic, Javier Cano-Lou, Gema Casado, Susana Machado, Liliana Espírito Santo, Beatriz Oliveira, Eliana Pereira, Lillian BarrosValorising vegetable by-products is a sustainable and innovative strategy to […]Tatiane C De Oliveira
- Gut Microbiota-Dependent Metabolism of 6-Shogaol Generates Bioactive Metabolites That Mediate Its Anti-Inflammatory Effects June 11, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D6FO01722C, PaperShuwei Zhang, Yantao Zhao, Rachel C Newsome, Yingdong Zhu, Christian Jobin, Shengmin Sanga 6-Shogaol (6S), a major bioactive constituent of ginger, exhibits anti-inflammatory activity, but the contribution of gut microbiota to its metabolism and biological effects remains unclear. Using germ-free (GF) and...The content of this RSS Feed (c) The […]Shuwei Zhang
- Effects of microalgae incorporation on nutrient digestibility and antioxidant activity of gluten-free muffins after simulated chewing and digestion in adults and older adults June 11, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D6FO01526C, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Milagros Arnal, Susana Ribes, Nuria Belenguer, Pau TalensThis study evaluated the effects of microalgae incorporation, chewing conditions, and digestive models on nutrient digestibility, total phenolic content, and antioxidant activity of gluten-free muffins using in […]Milagros Arnal
- Aged garlic extract suppressed macrophage-mediated inflammation in acute respiratory distress syndrome June 11, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D6FO00337K, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Shun Nakazawa, Shinsaku Togo, Chisato Tadokoro, Soichiro Soma, Yuta Arai, Hiroaki Motomura, Yuichi Nagata, Takuto Sueyasu, Haruki Hirakawa, Koichi Kurata, Issei Sumiyoshi, Yusuke Ochi, Junko Watanabe, Hiroaki Ihara, Kazuaki Hoshi, Motoyasu Kato, Kazuhisa TakahashiCombining […]Shun Nakazawa
- Apples and apple-based products in the modulation of cardiometabolic and functional markers: a systematic review of human intervention studies June 10, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO05460E, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Cristian Del Bo’, Daniela Martini, Anna Giancristofaro, Marco Rendine, Mirko Marino, Maria Cristina Casiraghi, Patrizia RisoApple is one of the most widely consumed fruits worldwide, yet its effects on human health remain the […]Cristian Del Bo’
- Non-ethanol components of Baijiu alleviate ethanol-induced energy metabolism disorder and gut microbiota dysbiosis in mice June 10, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D6FO00947F, PaperYingrui Gao, Weiman Zhao, Ruonan Tong, Xiaojun Wu, Zhengtao Wang, Longchan Liu, Li YangBaijiu non-ethanol components restore ethanol-induced energy metabolism disorder and microbiota dysbiosis, normalize the NADH/NAD+ redox balance, and reduce lactate overaccumulation, thereby relieving ethanol-induced oxidative stress.To cite this article before page numbers are assigned, use the DOI […]Yingrui Gao
- Nut consumption as a therapeutic strategy to preserve brain function, attenuate neuropathology, and modulate cross-tissue microRNAs in a mouse model of Alzheimer's disease June 9, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D6FO00445H, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Laura Panisello, Mireia Millet-Sigalat, Nil Novau-Ferré, Javier Mateu-Fabregat, Marina Carrasco, Miren Ettcheto, Elisa Félix-Soriano, antoni camins, M. BulloNutritional modulation of brain metabolism is emerging as a key strategy for preventing Alzheimer’s Disease (AD), with […]Laura Panisello
- Lactobacillus plantarum ameliorates high-fat-diet-induced dyslipidemia via cholesterol metabolism and gut microbiota modulation June 9, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D6FO00519E, PaperZiyue Zhou, Yin Mao, Jinyang Li, Ju Yang, Yihui Zhang, Yunying Zhao, Yu DengDyslipidemia, a typical metabolic disorder, is predominantly characterized by elevated levels of total cholesterol (TC) and/or triglycerides (TG), with disruption of cholesterol homeostasis serving as a significant contributing factor. This...The content of this RSS Feed (c) […]Ziyue Zhou
- Inhibition of the in vitro colonic fermentation of cooked gluten by dietary fibers with individual fermentability June 9, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D6FO00694A, PaperDan Yuan, Tianyi Li, Ying Li, Xingyu Tao, Zhiming Gao, Yuehan Wu, Wenxin Jiang, Yanlei Li, Xuewen Ni, Mengzhou ZhouAlginate inhibited gluten fermentation by shielding gut microbiota from degrading gluten due to its durable fermentability. FOS inhibited gluten fermentation only for a short period of time. Cellulose even promoted […]Dan Yuan
- Selenium-enriched Tibetan kefir grain-fermented goji juice attenuates patulin-induced liver injury and is associated with gut microbiota modulation in mice June 9, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D6FO01305H, PaperYifan Cheng, Jinyi Yang, Jinyue Xu, Xuejun Zeng, Kewei Feng, Yahong Yuan, Tianli YueSelenium-enriched Tibetan kefir grain-fermented goji juice attenuated patulin-induced liver injury by improving redox balance, reducing inflammation, and modulating gut microbiota-associated responses.To cite this article before page numbers are assigned, use the DOI form of citation above.The […]Yifan Cheng
- Dietary chlorogenic acid improves lipid metabolism through modulation of the gut–liver microbiota axis in hyperlipidemic mice June 9, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D6FO00434B, PaperAbdul Basit, Abdul Mueed, Raheem Shahzad, Wang Rong, Khanizadeh Shahrokh, Adeeb Shehzad, Salman Khan, Tao ShutianChlorogenic acid alleviates high-fat diet-induced hyperlipidaemia and glucose dysregulation by modulating gut microbiota, remodeling metabolite networks, reducing hepatic lipid accumulation, and activating IRS1/CD36 signalling pathways.To cite this article before page numbers are assigned, use […]Abdul Basit
- Animal-based diets and the human gut microbiota: a narrative review integrating metagenomic profiling and graphical synthesis of diet–microbiota associations June 9, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D6FO00371K, Review ArticleLamia Medouni-Haroune, Sonia Medouni-Adrar, Lynda Messaoudene, Samira NEGRICHI, Cilia BOUICHE, Yasmine Sahraoui-Remini, Ayoub Allam, Zoubeida Meghlaoui, Khokha Mouhoubi, Amina ABBOU, Nassim BRAHIMI, Mohamed Khalil MELLAL, Zoubir Sari, Khodir MadaniThis review examines the relationships between animal-based diets, gut microbiota architecture, and human health by integrating insights from metagenomic studies […]Lamia Medouni-Haroune
- Tibetan kefir grain-fermented milk attenuates DSS-induced colitis through coordinated regulation of intestinal barrier function, inflammation, and gut microbiota June 8, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D6FO01565D, PaperBen Li, Shuai Li, Yihao Pei, Xiaojuan Sun, Chen Ding, Jin Yu, Meiling Zhou, Jianmei Han, Hong Yang, Yafan WanThis study links the complete kefir-fermented milk matrix to colitis prevention through integrated host, microbiota, metagenomic, and metabolomic analyses.To cite this article before page numbers are assigned, use the DOI […]Ben Li
- Food-derived peptides for senile sarcopenia: mechanisms of action, structural characteristics, and in vivo delivery challenges June 7, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D6FO00948D, Review ArticleManqun Wang, Wanlu Liu, Jiulong An, Xinting Luo, Janar Jenis, Xinqi Liu, He LiFood-derived peptides (FDPs) are attracting increasing research attention for intervention in age-related sarcopenia due to their potential muscle-protective activity.To cite this article before page numbers are assigned, use the DOI form of citation above.The content […]Manqun Wang
- Sturgeon roe protein hydrolysate alleviates cyclophosphamide-induced ovarian dysfunction in mice with reduced ovarian oxidative-inflammatory injury, granulosa-cell apoptosis, and HPO-axis-related endocrine imbalance June 7, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D6FO02422J, PaperSilu Zhang, Hailong Li, Lijia Yang, Penglong Liu, Tingfeng Zhang, Yangyan Dai, Yuchen Pang, Shijing Ma, Mouming Zhao, Tiantian ZhaoChemotherapy-associated ovarian dysfunction is closely linked to oxidative–inflammatory injury of the follicular microenvironment, granulosa-cell loss, impaired steroidogenesis, and destabilized hypothalamic–pituitary–ovarian (HPO) axis feedback. This study evaluated sturgeon roe protein hydrolysate...The […]Silu Zhang
- Anti-inflammatory activity of orange peel aqueous extract and hesperidin : Integrated evidence from neutrophil assays, in vivo models, and in silico analyses June 14, 2026
