RSC – Mol. Omics latest articles
- Integrated multi-omic analyses of bovine milk identify biomarkers of negative energy balance. May 20, 2025Mol. Omics, 2025, Accepted ManuscriptDOI: 10.1039/D4MO00190G, Research ArticleAntoine Leduc, Andrea Rau, Denis Laloë, Sandrine Le Guillou, Patrice Martin, Marine Gele, José A.A. Pires, Yannick Faulconnier, Christine Leroux, Marion Boutinaud, Fabienne Le ProvostDairy cows are susceptible to negative energy balance, which can lead to metabolic disorders such as ketosis. Negative energy balance often occurs in early […]Antoine Leduc
- Integrating N-glycan and CODEX imaging reveal cell-specific protein glycosylation in healthy human lung May 19, 2025Mol. Omics, 2025, Advance ArticleDOI: 10.1039/D4MO00230J, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Dušan Veličković, Jeffrey Purkerson, Harsh Bhotika, Heidie Huyck, Geremy Clair, Gloria S. Pryhuber, Christopher AndertonIdentifying cell-specific glycan structures in human lungs is critical for understanding the chemistry and mechanisms that guide cell–cell and […]Dušan Veličković
- Lipid profiling: proving the geographical origin of strawberries (Fragaria × ananassa) using a non-targeted LC-IM-MS approach May 15, 2025Mol. Omics, 2025, Advance ArticleDOI: 10.1039/D5MO00006H, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Johannes Brockelt, Felix Schmauder, Marina Creydt, Markus FischerDifferentiation of strawberries from six different origins. Analysis of the lipid profile was performed using LC-IM-MS method. Geographical origin differentiation by identification of significant lipids.To cite […]Johannes Brockelt
- Integration of focal adhesion morphogenesis and polarity by DOCK5 promotes YAP/TAZ-driven drug resistance in TNBC May 11, 2025Mol. Omics, 2025, Advance ArticleDOI: 10.1039/D4MO00154K, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Patricia Pascual-Vargas, Mar Arias-Garcia, Theodoros I. Roumeliotis, Jyoti S. Choudhary, Chris BakalDOCK5 acts at focal adhesions in breast cells to establish positive feedback loops via CDC42 and RAC The stabilisation of polarity during […]Patricia Pascual-Vargas
- A multi-omics machine learning classifier for outgrowth of cow's milk allergy in children May 8, 2025Mol. Omics, 2025, Advance ArticleDOI: 10.1039/D4MO00245H, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Diana M. Hendrickx, Mariyana V. Savova, Pingping Zhu, Ran An, Sjef Boeren, Kelly Klomp, Sumanth K. Mutte, PRESTO study team, Harm Wopereis, Renate G. van der Molen, Amy C. Harms, Clara BelzerA multi-omics […]Diana M. Hendrickx
- Analysis of FAIMS for the study of affinity-purified protein complexes using the orbitrap ascend tribrid mass spectrometer May 6, 2025Mol. Omics, 2025, Advance ArticleDOI: 10.1039/D5MO00038F, Research ArticlePratik Goswami, Joseph Cesare, Michaella J. Rekowski, Zachary Clark, Janet Thornton, Michael P. WashburnThe impact of the use of FAIMS on an affinity purification of protein complexes was studied and found that FAIMS significantly reduced specific contaminating ions.To cite this article before page numbers are assigned, use the […]Pratik Goswami
- PPI network identifies interacting pathogenic signaling pathways in Candida albicans April 30, 2025Mol. Omics, 2025, Advance ArticleDOI: 10.1039/D5MO00042D, Research ArticleDeepanjan Chattopadhyay, Sanjib Das, Paromita Saha Mondal, Tanushree Mondal, Subhasree Samanta, Amalesh Mondal, Achintya Mohan Goswami, Tanima SahaIdentification of interacting pathogenic signaling pathways in Candida albicans through PPI network studies.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed […]Deepanjan Chattopadhyay
- Characterizing metabolic dysregulation in early-stage chronic kidney disease for diagnostic insights April 24, 2025Mol. Omics, 2025, Advance ArticleDOI: 10.1039/D5MO00018A, Research ArticleUpasna Gupta, Amrita Sahu, Dharmendra Singh Bhadauria, Bikash Baishya, Neeraj SinhaUnderstanding these metabolic and pathophysiological processes and discovering relevant biomarkers enables early identification, individualized treatment plans, and the possibility of slowing down or even reversing the progression of CKD.To cite this article before page numbers are assigned, use […]Upasna Gupta
- Proteomic and metabolomic dissection of the BRAF V600E mutation-induced cellular state transition in lung epithelial cells April 22, 2025Mol. Omics, 2025, Advance ArticleDOI: 10.1039/D4MO00249K, Research ArticleFengting Liu, Fan Yang, Hailin Xiong, Jingnan Huang, Zhenhui Huang, Jingying Song, Xinyi Liu, Hongchao Zhou, Jing Xu, Jimin Yuan, Lin Jia, Lingyun DaiThis study established a BRAF V600E knock-in BEAS-2B cell model that allows us to systematically dissect the underlying molecular events involved in the cellular state […]Fengting Liu
- Retraction: Tetracycline-controllable artificial microRNA-HOTAIR + EZH2 suppressed the progression of bladder cancer cells April 21, 2025Mol. Omics, 2025, 21,250-250DOI: 10.1039/D5MO90007G, Retraction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Yincong Chen, Haibiao Xie, Yifan Zou, Xiulan Lai, Lian Ma, Yuchen Liu, Jianfa LiThe content of this RSS Feed (c) The Royal Society of ChemistryYincong Chen
- Transcriptome profiling of serum exosomes by RNA-Seq reveals lipid metabolic changes as a potential biomarker for evaluation of roxadustat treatment of chronic kidney diseases March 17, 2025Mol. Omics, 2025, 21,240-249DOI: 10.1039/D4MO00025K, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Ru Zhou, YaXuan Zhen, Hualin Ma, Zhen Wang, LiXia Liu, Xinzhou Zhang, Baochun GuoRoxadustat alters serum exosomal mRNA–lncRNA profiles in CKD. These findings highlight a novel regulatory axis linked to lipid metabolism, enhancing treatment […]Ru Zhou
- Exon–intron boundary detection made easy by physicochemical properties of DNA March 11, 2025Mol. Omics, 2025, 21,226-239DOI: 10.1039/D4MO00241E, Research ArticleDinesh Sharma, Danish Aslam, Kopal Sharma, Aditya Mittal, B. JayaramChemEXIN is an advanced tool for the accurate prediction of exon–intron boundaries in eukaryotic genomes. It utilizes biophysical features and deep learning methods for robust performance, making it a versatile tool for exon–intron prediction.The content of this RSS Feed (c) […]Dinesh Sharma
- Revealing the dynamics of fungal disease with proteomics February 20, 2025Mol. Omics, 2025, 21,173-184DOI: 10.1039/D4MO00222A, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Mariana Sa, Mayara da Silva, Brianna Ball, Jennifer Geddes-McAlisterMass spectrometry-based proteomics defines novel drivers of fungal pathogenesis. These new avenues of investigation enable researchers to tackle fungal infections from prevention to treatment for improved […]Mariana Sa
- Unmasking the lipid landscape: carbamazepine induces alterations in Leydig cell lipidome February 4, 2025Mol. Omics, 2025, 21,202-214DOI: 10.1039/D4MO00221K, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Inês Nobre, Inês M. S. Guerra, Marisa Pinho, Ana D. Martins, Laura Goracci, Stefano Bonciarelli, Tânia Melo, Pedro Domingues, Artur Paiva, Pedro F. Oliveira, M. Rosário DominguesLeydig cells rely on lipids and fatty acids […]Inês Nobre
- Unraveling the phenotypic and metabolic responses induced by urea-encapsulated hydrogel beads on Brassica juncea (L.) Czern & Coss January 28, 2025Mol. Omics, 2025, 21,215-225DOI: 10.1039/D4MO00192C, Research ArticleMuthumari Balakrishnan, Vignesh Kumar Balasubramanian, Kavitha Murugan, John Praveen Kumar John Kennedy, Subashri Dhanasekaran, Shih-Feng Fu, Shang-Tse Ho, Jothi Basu Muthuramalingam, Jui-Yu ChouUrea-encapsulated hydrogels were synthesized using plant biopolymers. The phenotypic parameters and metabolic response of B. juncea were evaluated and the variations between hydrogel-based urea delivery and direct […]Muthumari Balakrishnan
- Enhanced anti-inflammatory and anti-fibrotic effects of nanoparticles loaded with a combination of Aloe vera–Moringa oleifera extracts December 26, 2024Mol. Omics, 2025, 21,185-201DOI: 10.1039/D4MO00195H, Research ArticleGabriela I. Carballo-López, Jhordan Ojeda-González, Kevin D. Martínez-García, Karla E. Cervantes-Luevano, Aldo Moreno-Ulloa, Ana B. Castro-CeseñaSynergistic effect of combined Aloe vera and Moringa oleifera extracts enhanced cytocompatibility in hepatic stellate cells and modulated profibrotic genes.The content of this RSS Feed (c) The Royal Society of ChemistryGabriela I. Carballo-López
- Integrated multi-omic analyses of bovine milk identify biomarkers of negative energy balance. May 20, 2025