Molecular Omics

RSC – Mol. Omics latest articles

• Transcriptome profiling of serum exosomes by RNA-Seq reveals lipid metabolic changes as a potential biomarker for evaluation of roxadustat treatment of chronic kidney diseases March 17, 2025
  Mol. Omics, 2025, Advance ArticleDOI: 10.1039/D4MO00025K, Research Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Ru Zhou, YaXuan Zhen, Hualin Ma, Zhen Wang, LiXia Liu, Xinzhou Zhang, Baochun GuoRoxadustat alters serum exosomal mRNA–lncRNA profiles in CKD. These findings highlight a novel regulatory axis linked to lipid metabolism, enhancing […]
  Ru Zhou
• Lipidomics reveals cell specific changes during pluripotent differentiation to neural and mesodermal lineages March 13, 2025
  Mol. Omics, 2025, Advance ArticleDOI: 10.1039/D4MO00261J, Research Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Melanie T. Odenkirk, Haley C. Jostes, Kevin R. Francis, Erin S. BakerLipidomic analyses of induced pluripotent stem cells at critical stages of differentiation toward neural or mesodermal fates illustrate unique species and class-based […]
  Melanie T. Odenkirk
• Exon–intron boundary detection made easy by physicochemical properties of DNA March 11, 2025
  Mol. Omics, 2025, Advance ArticleDOI: 10.1039/D4MO00241E, Research ArticleDinesh Sharma, Danish Aslam, Kopal Sharma, Aditya Mittal, B. JayaramChemEXIN is an advanced tool for the accurate prediction of exon–intron boundaries in eukaryotic genomes. It utilizes biophysical features and deep learning methods for robust performance, making it a versatile tool for exon–intron prediction.To cite this article before page […]
  Dinesh Sharma
• Revealing the dynamics of fungal disease with proteomics February 20, 2025
  Mol. Omics, 2025, Advance ArticleDOI: 10.1039/D4MO00222A, Review Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Mariana Sa, Mayara da Silva, Brianna Ball, Jennifer Geddes-McAlisterMass spectrometry-based proteomics defines novel drivers of fungal pathogenesis. These new avenues of investigation enable researchers to tackle fungal infections from prevention to treatment for […]
  Mariana Sa
• Proteomic analysis reveals anticancer mechanisms of Bhallataka taila in inhibiting lung cancer progression and metastasis January 2, 2025
  Mol. Omics, 2025, 21,122-134DOI: 10.1039/D4MO00156G, Research ArticleSuchitha G. P., Akhila B. Rai, Ravishankar Pervaje, Chinmaya Narayana Kotimoole, Prashant Kumar Modi, T. S. Keshava Prasad, Shobha DagamajaluBhallataka taila slows lung cancer progression by reducing proliferation, migration, and EMT while enhancing apoptosis. Proteomic analysis reveals the regulation of vital pathways involved in metastasis, invasion, and EMT.The content […]
  Suchitha G. P.
• Integrating OMICS-based platforms and analytical tools for diagnosis and management of pancreatic cancer: a review December 23, 2024
  Mol. Omics, 2025, 21,108-121DOI: 10.1039/D4MO00187G, Review ArticlePatrícia Sousa, Laurentina Silva, José S. Câmara, Paula Guedes de Pinho, Rosa PerestreloIntegrating OMICS-based platforms and analytical tools for diagnosis and management of pancreatic cancer.The content of this RSS Feed (c) The Royal Society of Chemistry
  Patrícia Sousa
• The investigation of early metabolic level perturbation of northern quahog (Mercenaria mercenaria) in response to brevetoxin December 19, 2024
  Mol. Omics, 2025, 21,143-151DOI: 10.1039/D4MO00207E, Research ArticleBo Wang, Nicole McKenna, Julie Pollak, Moses Mayonu, Lin JiangNMR metabolomics was applied to M. mercenaria exposed to a series of sublethal doses of Brevetoxins for the targeted metabolic pathway and early marker discovery.The content of this RSS Feed (c) The Royal Society of Chemistry
  Bo Wang
• Differential modulation of the hepatocellular metabolome, cytoprotective and inflammatory responses due to endotoxemia and lipotoxicity December 17, 2024
  Mol. Omics, 2025, 21,152-163DOI: 10.1039/D4MO00140K, Research Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Jyoti Sharma, Priyankar DeyThe present work aimed to examine the primary mechanisms of liver damage, namely the impact of gut-derived endotoxins on the gut–liver axis and adipose-derived free fatty acids on the adipose–liver axis.The […]
  Jyoti Sharma
• Selective labeling of tyrosine residues in proteins: insights from PTAD labeling and tandem mass spectrometry analysis December 2, 2024
  Mol. Omics, 2025, 21,135-142DOI: 10.1039/D4MO00186A, Research ArticleAdway O. Zacharias, Sharel Cornelius, Saiful M. ChowdhuryEvaluation of the tyrosine labeling reagent PTAD for protein covalent labeling studies using tandem mass spectrometry.The content of this RSS Feed (c) The Royal Society of Chemistry
  Adway O. Zacharias