RSC – RSC Chem. Biol. latest articles- Experimental identification of preQ1-binding RNAs in the pathogenic bacterium Listeria monocytogenes October 13, 2025RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D5CB00102A, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Malou Hanisch, Laurin Flemmich, Christoph Mitteregger, Ingo Bauer, Cristian A. Velandia-Huerto, Ivo Hofacker, Ronald Micura, Alexandra LusserPull-down, chemical, and functional analysis of preQ1-binding RNAs: Validation of a predicted preQ1 riboswitch binding two preQ1 […]Malou Hanisch
- New Insights into the Structure and Dynamics of the Epigenetic Modifications on DNA October 12, 2025RSC Chem. Biol., 2025, Accepted ManuscriptDOI: 10.1039/D5CB00207A, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Dineshbabu Takkella, Javier Cerezo, Lara Martinez-Fernandez, Krishna GavvalaDNA methylation is a key epigenetic modification involved in genomic imprinting, Xchromosome inactivation, and repression of repetitive element transcription and transposition.Despite its biological significance, the impact […]Dineshbabu Takkella
- Alkyne-tagged ribitol-5-phosphate derivatives for metabolic labelling of alpha-dystroglycan October 9, 2025RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D5CB00187K, Communication Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Lloyd D. Murphy, Saeed Akkad, Angelo Lopez, Morgan E. Batiste-Simms, Greg L. McNeil, Eva W. Wan, Kathryn E. Huxley, Luke Julyan, Mia Shandell, Lianne I. WillemsA chemical reporter strategy is described for the […]Lloyd D. Murphy
- Chemically Inducible Antisense Oligonucleotides for Cell-Specific Gene Silencing October 8, 2025RSC Chem. Biol., 2025, Accepted ManuscriptDOI: 10.1039/D5CB00186B, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Zhen Xun, Yang Hai, Lijuan Tang, Jian-Hui Jiang, Zhenkun WuThe ability of cell-specific control of the function of antisense oligonucleotides (ASO) is highly desirable for precise gene therapy with minimizing adverse effect in […]Zhen Xun
- A disubstituted aniline probe for enhanced peroxidase-based proximal protein labelling October 7, 2025RSC Chem. Biol., 2025, Accepted ManuscriptDOI: 10.1039/D5CB00095E, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Pornchai Kaewsapsak, Nattavorapon Tantisasirat, Sucheewin Krobthong, Peeraphan Compiro, Ariya Khamwut, Kidakarn Ratchakitprakarn, Naphat Chantaravisoot, Kriangsak Faikhruea, Withsakorn Sangsuwan, Medena Noikham, Worawan Bhanthumnavin, Tirayut Vilaivan, Sunchai Payungporn, Yodying Yingchutrakul, Watthanachai Jumpathong, Chanat AonbangkhenProteins are […]Pornchai Kaewsapsak
- Biocatalytic synthesis of phenyl benzoate esters using the amide ligase ClxA October 7, 2025RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D5CB00205B, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Alexander Ascham, Qingyun Tang, Ian J. S. Fairlamb, Gideon GroganThe ligase ClxA catalyses the synthesis of phenyl benzoate esters from benzoic acids and phenols and can be engineered for broadened substrate specificity.To cite […]Alexander Ascham
- Comparative Aptamer Profiling Reveals Cell Surface Remodeling and Emergence of Noncanonical Cell Surface Protein Under Oncogenic Signaling October 2, 2025RSC Chem. Biol., 2025, Accepted ManuscriptDOI: 10.1039/D5CB00110B, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Jungo Kakuta, Kenji Ohba, Hideaki Ogasawara, Kyohei Okahara, Kazumi Emoto, Hiroaki Sako, Miho Sekai, Yasuyuki Fujita, Toshio Imai, Yogo SakakibaraIdentifying cell type-specific molecular markers on the cancer cell surface is essential for understanding […]Jungo Kakuta
- Glyco-functionalization of ECM mimics, influence in morphology and cell behaviour October 2, 2025RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D5CB00185D, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Maddalena Bracchi, Francesco Nicotra, Laura RussoGlycans are known to regulate cell fate. ECM-mimicking hydrogels conjugated with α-D-glucopyranose and β-D-galactopyranose were developed to study effects on cell morphology and behaviour, showing distinct glycosignatures and […]Maddalena Bracchi
- Identification of ligands for E3 ligases with restricted expression using fragment-based methods October 1, 2025RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D5CB00198F, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Alex G. Waterson, Brian D. Lehmann, Zhenwei Lu, John L. Sensintaffar, Edward T. Olejniczak, Bin Zhao, Tyson Rietz, William G. Payne, Jason Phan, Stephen W. FesikNMR-based screening identified fragment hits that bind to […]Alex G. Waterson
- Thiazole peptidomimetics as chemical modulators of KRAS gene expression via G-quadruplex stabilization October 1, 2025RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D5CB00046G, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Debasmita Biswas, Ananta Gorai, Sandip Maiti, Ritapa Chaudhuri, Sayantan Pradhan, Jyotirmayee DashBis-thiazole peptidomimetic TTh2 selectively binds and stabilizes the KRAS promoter G-quadruplex, leading to KRAS downregulation and inhibition of MAPK and Akt/mTOR pathways, […]Debasmita Biswas
- Experimental identification of preQ1-binding RNAs in the pathogenic bacterium Listeria monocytogenes October 13, 2025
