RSC – Anal. Methods latest articles- Spatial metabolomics in medicinal plant research: Current advances, technical challenges, and future perspectives June 29, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00572A, Critical ReviewYating Gong, Dongfeng Yang, Zhuoni HouSecondary metabolites derived from medicinal plants represent a critical resource for drug discovery and play an indispensable role in the prevention and treatment of major human diseases. Spatial metabolomics has...The content of this RSS Feed (c) The Royal Society of ChemistryYating Gong
- PdPt Bimetallic Nanozyme-Based Colorimetric Sensor for Sensitive and Label-Free Detection of Gossypol June 29, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00890A, PaperYun Wang, Manman Liu, Wenhui Zhang, Qian Zhang, Xiaoling Zhang, Tian Li, Xixi Hou, Suna HeIn this work, PdPt bimetallic nanoparticles with robust oxidase-like activity were synthesized, based on which a label-free, H₂O₂-free colorimetric platform was constructed for gossypol detection. The PdPt nanozyme activates dissolved...The content of this RSS […]Yun Wang
- Revisiting biofilms quantification: Crystal Violet Assay and the emerging role of Hyperspectral Imaging June 29, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00772D, Communication Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Abhishek Kandikatla, Jitendra Shit, Aala Suresh, Vidhya Das, Sonika Kar, Sunil Chinnadurai, Vazhora Malayil Manikandan, Sarfaraz Hussain, Jayaseelan MurugaiyanBacterial biofilms are major contributors to persistent and chronic infections. Conventional methods to quantify biofilm, such […]Abhishek Kandikatla
- A Luminescent Metal-Organic Polyhedron for Enzyme-Free Detection of Uric Acid June 29, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY01045H, PaperWenjing Zhang, Bin Zhao, Weiping Yang, Xiujuan Xu, Wenjuan Zhang, Kai Cui, Chunqiang Yang, Ajuan YuRapid and reliable detection of uric acid (UA) in human biological fluids is important for the early screening and monitoring of metabolic-related diseases. In this work, an enzyme-free fluorescence sensing...The content of this RSS […]Wenjing Zhang
- Emerging Trends in Amino Acid Detection: Wearable Devices and Machine Learning-Assisted Signal Processing June 28, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00596A, Critical ReviewHui Xu, Lican He, Yu Wei, Yanqin Chen, Jian ShuAs critical metabolic biomarkers, amino acids exert essential physiological functions, and their abnormal levels are closely associated with a range of diseases such as cancer, neurodegenerative disorders, and cardiovascular conditions....The content of this RSS Feed (c) The Royal Society […]Hui Xu
- Atomic Force Microscopy in Lung Cancer: From Mechanobiology to Clinical Translation June 28, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00786D, Critical ReviewShuwei Wang, Fan Yang, Mengnan LiuAtomic force microscopy (AFM) enables the nanoscale investigation of cellular mechanics, morphology, and molecular interactions under conditions that closely mimic physiological environments. This review synthesizes AFM analytical methodologies relevant to...The content of this RSS Feed (c) The Royal Society of ChemistryShuwei Wang
- Silver nanocluster-based nanoprobe for thiram determination in food and environment June 28, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00954A, CommunicationHui Dong, Xin-Ru Sun, Jing Zhu, Wei Wang, Zhong-Xia WangA novel silver nanocluster (AgNCs) nanoprobe was prepared using a pyrimidine derivative, 4,6-diamino-2-mercaptopyrimidine, as surface-ligand and reductant for sensitive and selective monitoring of the fungicide thiram (Thi). AgNCs exhibited a...The content of this RSS Feed (c) The Royal Society of […]Hui Dong
- Eco-friendly flow injection amperometric determination of tert-butylhydroquinone in edible oil samples using micelle-mediated reverse-phase dispersive liquid-liquid microextraction and unmodified screen-printed carbon electrode June 28, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY01019A, PaperCesar Ricardo Teixeira Tarley, Renata Vieira Conceição, Maikon Thiago do Nascimento, Mayara da Silva Araújo, Roberta Antigo Medeiros, Mariana Gava SegatelliLipid oxidation compromises the stability of edible oils, especially refined ones, due to reduced natural antioxidants. Synthetic antioxidants like tert-butylhydroquinone (TBHQ) are widely used but require careful monitoring. This […]Cesar Ricardo Teixeira Tarley
- 3D-Printed Electrochemical Sensors for Sustainable Electroanalysis: A Critical Assessment of Materials, Green Strategies, and Circular Economy Perspectives June 28, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00757K, Critical ReviewRaquel G. Rocha, Lucas V. de Faria, Luiz R. C. Silva, Rafael M. Dornellas, Bruno C. Janegitz, Jéssica Stefano, Diego Pessoa RochaAdditive manufacturing (AM) has emerged as a powerful strategy for the fabrication of electrochemical sensors, enabling low-cost, miniaturized, and customizable devices with reduced material consumption. Among the […]Raquel G. Rocha
- Spectrofluorimetric method for determination of the skin depigmenting substance – 4-hexylresorcinol – in cosmetic products June 28, 2026Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D6AY01006G, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Marianna Ntorkou, Emmanouela Katzouraki, Vasileios D. Alampanos, Constantinos K. ZacharisThis study reports a rapid and sensitive batch spectrofluorimetric method for the quantification of 4-hexylresorcinol in cosmetic formulations.To cite this article before page numbers are […]Marianna Ntorkou
- AFM-based nanomechanical evaluation of human umbilical cord mesenchymal stem cells for alcohol-associated liver injury June 25, 2026Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D6AY00703A, PaperJinhong Fu, Qiuyang Deng, Jie Jiao, Yujuan Chen, Xiyao Yin, Zuobin WangAFM reveals that umbilical cord MSCs protect against alcohol-associated liver injury by restoring cytoskeletal organization, nanomorphology, and mechanical homeostasis in injured hepatocytes.To cite this article before page numbers are assigned, use the DOI form of citation above.The content […]Jinhong Fu
- A smartphone-assisted dual-mode colorimetric sensing system for on-site detection of ciprofloxacin: experimental and DFT insights June 25, 2026Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D6AY00817H, PaperSara M. Ragab, Elhossein A. Moawed, Mohamed M. AboelngaThe development of portable, cost-effective, and user-friendly analytical tools for one-site detection of ciprofloxacin (CIP) in complex matrices remains a significant challenge.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS […]Sara M. Ragab
- Differential Analysis of Ginseng Methanol Extracts From Different Origins using FTIR and 2D-COS-IR June 25, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00792A, Technical NoteChen Chen, Haomiao Han, Kunlun Xue, Hongli Zhou, Xing JinThe quality of ginseng is largely determined by its ginsenoside. However, the high similarity among such extracts poses a considerable challenge to the rapid and differentiation of their origins, which...The content of this RSS Feed (c) The Royal Society […]Chen Chen
- Synergistic integration of bidirectional PER and DNAzyme cascades with ZIF-8 quenching for detection of aflatoxin B1 June 25, 2026Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D6AY00837B, PaperZiyan Zhao, Yijing Xiao, Chunyuan Huo, Wentong Yu, Shuangyu Meng, Runlong Ma, Zhiqiang Guo, Xinru Ren, Haiping Zhang, Bowen Li, Yu Wang, Su Liu, Jiadong HuangWe have developed an OFF-ON fluorophore sensor that integrates BPER amplification, DNAzyme cleavage and ZIF-8 quenching for AFB1 detection, featuring high specificity and a […]Ziyan Zhao
- Unmasked G-quadruplexes for real-time fluorescence detection of viral genomic RNA June 24, 2026Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D6AY00654J, PaperZahra Alkhamis, Fatemeh Javadi-ZarnaghiReal-time (RT) PCR is currently one of the most powerful molecular approaches for diagnosing infectious diseases. This report combines real time (RT)-PCR with fluorescence detection of viruses via thioflavin interaction with G-quadruplexes.To cite this article before page numbers are assigned, use the DOI form of citation […]Zahra Alkhamis
- On hidden and visible charges in mass spectrometry: Alternative approaches in mass spectra interpretation June 24, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00333H, Tutorial ReviewDimitrios TsikasGas chromatography-mass spectrometry (GC-MS) mass spectra of organic molecules contain ions that are generated in the ion-source of GC-MS apparatus. Electron ionization (EI) generates cations; chemical ionization (CI) generates either...The content of this RSS Feed (c) The Royal Society of ChemistryDimitrios Tsikas
- Molecularly imprinted polymer-based fluorescent sensors for rapid and specific detection of target pesticides June 24, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00999A, PaperHaoqi Jia, Rui Li, Xiaoxiao Hong, Xin Dong, Shengxue Ye, Weiwei Li, Jianlin Li, Fenying Wang, Qianjin LiThis study presents a novel fluorescence sensing platform based on molecularly imprinted polymers (MIPs) for the detection of imidacloprid and chlorpyrifos, two widely used pesticides with potential food safety risks....The content of […]Haoqi Jia
- Salt-free in-solution surface-enhanced Raman spectroscopy substrates based on gold nanoparticle-decorated silica spheres June 23, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY01087C, PaperHuijun Mao, Mark T. McDermottNoble metal colloidal, such as gold and silver, have been widely used in the SERS analysis as the substrates. The method of narrowing the interparticle distance is a popular subject,...The content of this RSS Feed (c) The Royal Society of ChemistryHuijun Mao
- Self-Assembled Supramolecular Sensor for Hydrogen Sulfate via Multipoint Hydrogen Bonding: Real-Sample Analysis and Field-Deployable Paper-Based Detection June 23, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00430J, PaperNilanjan DeyHerein, a self-assembled rhodamine–indole based supramolecular probe (compound 1) has been reported for the selective and sensitive detection of hydrogen sulfate (HSO₄⁻) ions in aqueous medium. The probe exhibited aggregation-assisted...The content of this RSS Feed (c) The Royal Society of ChemistryNilanjan Dey
- Ag nanoparticles grown on waste eggshell membrane as an efficient monolithic oxidase mimic for ascorbic acid colorimetric detection June 23, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY01053A, PaperQiuxia Deng, Shuang Xiao, Jinyi Xie, Qin Liu, Daiping He, Ping Jiang, Dashui YuanNanozymes act as a promising alternative to natural enzymes in constructing colorimetric sensing platform for biosensing and food analysis, yet most nanozymes are in power form and requires special separation...The content of this RSS Feed (c) […]Qiuxia Deng
- Spatial metabolomics in medicinal plant research: Current advances, technical challenges, and future perspectives June 29, 2026
