RSC – Anal. Methods latest articles- A Benzothiazole -Based Fluorescent Probe for Hypochlorite -Highly Sensitive Detection and Live -Cell Imaging Research December 30, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01966D, PaperKelong Fang, Xiaozhen Ma, Yuliang JiangHypochlorous acid (HOCl), a key reactive oxygen species, is generated in vivo through the catalytic action of myeloperoxidase and plays a crucial role in innate immunity. However, dysregulation of HOCl...The content of this RSS Feed (c) The Royal Society of ChemistryKelong Fang
- Nanosensors as Diagnostic Tools: Emerging Concepts, Opportunities, and Design Barriers December 29, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01942G, Critical Review Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Babatunde Olamide Omiyale, Akinola Ogbeyemi, Wenjun Zhang, Muhammad Awais Ashraf, Ki-Young Song, haiyan yuNanosensors have become a revolutionary tool, enabling early diagnosis and continuous monitoring of diseases with high accuracy. These tiny devices, […]Babatunde Olamide Omiyale
- Selection of a DNA Aptamer for the Development of an Electrochemical Aptasensor for the Detection of Pb²⁺ December 29, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01525A, PaperZiyu He, Dan Wei, Kai Zhou, Changchun Hu, Chao Tang, Shuting Yang, Li Li, Tong Zhou, Yan DengIn order to develop a simple, highly sensitive and cost-effective electrochemical sensor with high specificity for lead ion (Pb2+), a method of modified magnetic beads-systematic evolution of ligands by exponential...The content of […]Ziyu He
- A novel electrochemical sensor for the analysis of vibegron as a newly approved FDA drug: A rational computational design and cleaning validation application December 29, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY02026C, PaperMahmoud A. Tantawy, Zeinab Goda, Suliman Almahmoud, Mina WadieA novel analytical tool was developed for the assay of the recently approved β3-adrenergic receptor agonist “vibegron”. This tool was also utilized for the cleaning validation process, in which the...The content of this RSS Feed (c) The Royal Society of ChemistryMahmoud A. Tantawy
- Hypoxia activated fluorescent probe for specific visualization of mitochondrial dysfunction in tumor December 29, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01970B, PaperQilong Zhang, Chun Dai, Huina Wang, Minggang Tian, Zhongwen Zhang, Ruoyao ZhangSelectively monitoring the mitochondrial dysfunction and viability of tumor was an important task for the treatment against cancer, which was helpful for controlling the appropriate radiotherapy and chemotherapy dose to...The content of this RSS Feed (c) The Royal […]Qilong Zhang
- An Integrated Magnetic-Microfluidic Chemiluminescence Platform for Rapid Quantification of Exosomal miR-21 Associated with Breast Cancer December 29, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01842K, PaperSamira Narimani Kohnehshahri, Fatemeh Etezadi, Mohammad Amin Hajari, Abdolah Razi, Mehdi Forouzandeh MoghadamAccurate quantification of microRNAs (miRNAs) is crucial for early cancer diagnosis, but conventional techniques, such as quantitative PCR and microarrays, are time-consuming, costly, and require complex instrumentation. In this study,...The content of this RSS Feed (c) The […]Samira Narimani Kohnehshahri
- A novel APE1-assisted cycling amplification for rapid and ultrasensitive SERS detection of TK1 mRNA in human serum December 26, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01669J, PaperChangqing Du, Anran Li, Jinye Qiu, Jiarui Sun, Xiaokun Wang, Wei Xu, Maofeng Zhang, Dapeng WangQuantitative mRNA expression levels are essential for differential and clinical diagnoses. In this work, we present an apurinic/apyrimidinic endonuclease 1 (APE1)-assisted SERS sensing platform for rapid and ultrasensitive detection of...The content of this RSS […]Changqing Du
- Untargeted UHPLC-Q-Orbitrap Metabolomics Reveals Hormonal Suppression and Candidate Serum Markers as Evidence of Testosterone Misuse in Cattle December 26, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01774B, PaperDiego G. Rocha, Mary A Lana, Débora C De Assis, Adriana FariaThe illicit use of androgenic anabolic steroids, such as 17β-testosterone, in food-producing animals poses significant risks to animal welfare and consumer safety. Detecting exogenous administration of endogenous hormones like testosterone...The content of this RSS Feed (c) The Royal […]Diego G. Rocha
- Correction: A portable fluorescent aptamer sensor for rapid quantitative detection of Hg2+ December 24, 2025Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY90167G, Correction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Jiayi Li, Xinyue Zhang, Zhiguang Suo, Xinyi Feng, Weiling Li, Baoshan He, Min Wei, Renyong ZhaoTo cite this article before page numbers are assigned, use the DOI form of citation above.The content of this […]Jiayi Li
- Characterizing Noninvasively Conservation Status of Historical Wet Collections using Spatially Offset Raman Spectroscopy December 24, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01654A, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Wren Montgomery, Chelsea Mckibbin, Ana Blanco-Rodrigues, Sam Walker, James Maclaine, Roberto Portela Miguez, Patrick Campbell, Robert Stokes, Pavel Matousek, Sara MoscaFluid-preserved specimens are central to the scientific and cultural value of natural history collections, […]Wren Montgomery
- Time-resolved thermal desorption miniature ion trap mass spectrometry for rapid and simultaneous quantification of multiple cooling agents in complex matrices December 24, 2025Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY01849H, PaperGuiyun Song, Huiwen Ruan, Zhigang Fan, Jianhua Wang, Weiguo Wang, Haiyang LiWe demonstrate rapid, simultaneous quantification of multiple cooling agents in complex matrices using a novel time-resolved thermal desorption technique coupled with miniature ion trap mass spectrometry.To cite this article before page numbers are assigned, use the DOI form […]Guiyun Song
- Establishment and evaluation of the detection method for human adenovirus and its subtypes based on RAA-LFD technology December 23, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01439E, PaperMengru Liu, Guiqi Hu, Yu Yu, Qingyang Sun, Chunli Yang, Mengyu Lv, Yue Wang, Yuzhu Dai, Jun ChengAbstract: In this research, we developed a rapid assay for detecting human adenovirus (HAdV) and its prevalent subtypes (including HAdV3, HAdV4, HAdV7, HAdV14, HAdV11, and HAdV55) based on recombinase-mediated isothermal...The content of […]Mengru Liu
- Ambient Ionization Mass Spectrometry for Rapid Screening of Illegal Adulteration in Traditional Chinese Medicines: A Review December 23, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY02001H, MinireviewFangliang Yang, Wei Shen, Jingjing YingIllegal adulteration of Traditional Chinese Medicines has become a critical global safety concern, driven by the covert addition of synthetic pharmaceuticals such as phosphodiesterase type five inhibitors, anorectic agents, nonsteroidal...The content of this RSS Feed (c) The Royal Society of ChemistryFangliang Yang
- Analytical methods for glycoRNA detection: A systematic review December 23, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01539A, MinireviewSijia Sun, Qian Liu, Zhen LiuGlycosylated RNAs (glycoRNAs) are a groundbreaking discovery in glycobiology, extending the diversity of known glycoconjugates beyond proteins and lipids. Accumulating evidence indicates their pivotal roles in cellular communication, immune regulation,...The content of this RSS Feed (c) The Royal Society of ChemistrySijia Sun
- A fast method based on programmed temperature vaporization-mass spectrometry for the quantification of 17α-ethinylestradiol and drospirenone in contraceptive formulations December 23, 2025Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY01770J, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Pablo Álvarez Alonso, Iria González-Mariño, Miguel del Nogal Sánchez, Ana Ballester-Caudet, Encarnación Rodríguez-Gonzalo, José Luis Pérez PavónA rapid method has been developed for the determination of 17α-ethinylestradiol and drospirenone in contraceptive formulations.To cite this […]Pablo Álvarez Alonso
- A Pt-loaded magnetic covalent organic framework with dual enzymatic activity for nanozyme-linked immunosorbent assay of SEB December 23, 2025Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY01674F, PaperHuiping Feng, Yue Sun, Jiang Wang, Jiwei Xu, Xihui Mu, Bin Du, Zhaoyang Tong, Bing LiuA tailored-pore, high-surface-area COF improves the dispersion, stability, and size control of Pt NPs. Their excellent dual enzyme-like activity enables a highly stable, specific, and sensitive sensing platform.To cite this article before page numbers […]Huiping Feng
- Geographical origin traceability analysis of camellia oil based on headspace gas chromatography-ion mobility spectrometry and chemometrics December 22, 2025Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY01886B, PaperShaojie Wu, Haojie Wu, Jirong Wu, You Zhou, Tingting Han, Daoming Chen, Jianbo Qiu, Xin Liu, Jianrong Shi, Jianhong Xu, Guanghui ShenGC-IMS combined with chemometric algorithms enables accurate identification of the geographical origin of camellia oil at both provincial and city levels, providing reliable technical support for geographical indication […]Shaojie Wu
- Construction and validation of a method for detecting DPP-IV activity and tissue distribution in C57 mice based on fluorescent probe December 22, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01757B, PaperBin Wang, Zi-Qiang Chen, Cong Hu, Si-Man Wang, Xingkai Qian, Liwei Zou, Ling YangDipeptidyl peptidase-IV (DPP-IV) is critical for drug metabolism and physiological regulation. In terms of species differences of DPP-IV, mouse an d human share a high degree of similarity，it is usually...The content of this RSS Feed (c) […]Bin Wang
- Establishment of the new dispersive solid phase microextraction method with green adsorbent CaAl-LDH hybrid with g-C 3 N 4 utilised for the determination of Pb 2+ in Instant cup noodles and environmental samples December 22, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01871D, PaperMuhammad Balal Arain, Abdul Niaz Abdul Niaz, Mustafa SoylakAdsorbents with a significant adsorption capacity and high selectivity are required to identify and eliminate heavy metal ions from the under study environmental and food samples. For this purpose, in...The content of this RSS Feed (c) The Royal Society of ChemistryMuhammad Balal Arain
- Gamma-hydroxybutyric acid (GHB) derivatization with N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide (EDC): LC-HRAM-Orbitrap-MS characterization of GHB and deuterated GHB derivatives and application to blood, urine, and hair analysis December 22, 2025Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY01461A, PaperGiampietro Frison, Arianna Negro, Flavio Zancanaro, Samuela Frasson, Gianpaola Tedeschi, Camilla Vigato, Giorgia MioloThis paper describes a new analytical approach for determining gamma-hydroxybutyric acid (GHB) in biosamples using liquid chromatography-mass spectrometry (LC-MS) following derivatization with N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide (EDC).To cite this article before page numbers are assigned, use the DOI form […]Giampietro Frison
- A Benzothiazole -Based Fluorescent Probe for Hypochlorite -Highly Sensitive Detection and Live -Cell Imaging Research December 30, 2025
