RSC – Anal. Methods latest articles- Measurement of ‘heavy metals’ in particulate matter in outdoor air January 8, 2026Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY90160J, AMC Technical Brief Analytical Methods Committee, AMCTB No. 120The theory and practice of the measurement of metals in particulate matter in outdoor air is explained, with relevant aspects of the application of these techniques in outdoor environments described.To cite this article before page numbers are assigned, use the DOI […]Analytical Methods Committee, AMCTB No. 120
- Strategic Immobilization of α-Amylase on ZIF-8 Nanoplatform for Targeted Bioactivity Screening in Gynura medica Extracts January 8, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01615K, PaperKe Ma, Yuying An, Yu-Qing Zhang, Gui-Fang ZhongThis study presents an enzyme immobilization strategy utilizing zeolitic imidazolate framework-8 (ZIF-8), a metal-organic framework (MOF) material synthesized in-house, for α-amylase immobilization, establishing a novel solid-phase extraction platform for targeted...The content of this RSS Feed (c) The Royal Society of ChemistryKe Ma
- Development of a novel MSRE-dPCR assay for non-invasive prenatal testing of Trisomy 21 January 8, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01569C, PaperChunmao Lin, Tan Wang, Boyang Han, Chenyu Jiang, Yang Ding, Huancai Yin, Liang Gao, Jian YinCurrently, next-generation sequencing (NGS)-based non-invasive prenatal diagnosis testing (NIPT) of fetal T21 has been proven to be much more advantageous than traditional serum biochemical tests in terms of accuracy and...The content of this RSS […]Chunmao Lin
- Analysis of dithiocarbamates in berries and leafy vegetables by ultra-high performance liquid chromatography coupled with tandem mass spectrometry January 8, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01566A, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Cécile Dionne Edoa, Ken Goeury, Justine Fontaine, Sébastien SauvéA sensitive method has been developed for the analysis of the three subclasses of dithiocarbamates (DTCs), (dimethyl dithiocarbamates (DMDs), ethylenebisdithiocarbamates (EBDs), propylenebisdithiocarbamates (PBD)) in berries and […]Cécile Dionne Edoa
- A flexible room-temperature CO2 sensor based on ethylenediamine-functionalized graphene oxide and polypyrrole microparticles composite film January 7, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01992C, PaperPi-Guey Su, Yi-Hui LaiA novel flexible, room-temperature chemiresistive CO₂ sensor was developed by coating a composite film of polypyrrole microparticles (PPy MPs) and ethylenediamine-functionalized graphene oxide (EDA-GO/PPy MPs) on a polyethylene terephthalate (PET)...The content of this RSS Feed (c) The Royal Society of ChemistryPi-Guey Su
- Random forest models accurately classify synthetic opioids using high-dimensionality mass spectrometry datasets January 7, 2026Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY01677K, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Kourosh Arasteh, Steven Magana-Zook, Colin V. Ponce, Roald Leif, Alex Vu, Mark Dreyer, Brian P. Mayer, Audrey M. Williams, Carolyn L. FisherDetection of novel threat agents presents several challenges, a principle one being the […]Kourosh Arasteh
- A label-free and universal CRISPR/Cas12a platform for the detection of hazardous substances in food January 7, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01887K, PaperWei Li, Meng Wang, Shuaijing WangThe present study proposes a label-free and universal CRISPR/Cas12a-based platform for the detection of hazardous substances in food. A label-free reporter, termed the G4 reporter, was carefully engineered. In the...The content of this RSS Feed (c) The Royal Society of ChemistryWei Li
- Wearable Electrochemical Biosensors for Non-Invasive Sport Doping Control: Sweat and Saliva as Dual Biofluid Platforms January 6, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01980J, MinireviewTaibin Huang, Ling Li, Jing Liang, Zhicheng Zhu, Zhiyu Yang, Ying XiThe integrity of competitive athletics is increasingly compromised by sophisticated pharmacologies, rendering traditional sporadic testing of urine and blood insufficient for comprehensive oversight. This critical review examines the emergence of...The content of this RSS Feed (c) The Royal […]Taibin Huang
- Analytical applications of gas-phase ion chemistry enabled by mass spectrometry January 6, 2026Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY00535C, Critical Review Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Woo-Young Kang, Boone M. PrenticeAnalytical mass spectrometry is used to study a variety of analytes, including metabolites, lipids, pharmaceutical compounds, pesticides, petroleum, proteins, protein complexes, nucleic acids, and glycans, across a wide range […]Woo-Young Kang
- MALDI Spatial Proteomics: A Mini Review of Approaches and Techniques January 5, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01341K, Minireview Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Arbil Lopez, Amanda HummonSpatial context is becoming increasingly important in the omics disciplines. Spatial proteomics is a diverse field encompassing numerous techniques that provide both the location and identity of proteins in biological...The content […]Arbil Lopez
- Tyrosinase detection via enzyme-triggered structural transformation of a ratiometric fluorescent probe January 2, 2026Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY01258A, CommunicationMinwoo Han, Haemin Choi, Juyeon Cha, Young-Sun Kim, Seoung Ho LeeTyrosinase-mediated oxidation of the fluorescent probe induces a distinct ratiometric fluorescence shift, providing a reliable platform for tyrosinase detection in complex media.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of […]Minwoo Han
- Portable platform with integrated colorimetric and electrochemical detection of nitrite and bisulfite in environmental and beverage samples January 2, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01827G, PaperGustavo R. Souza, Samuel C. Guerra, Priscila M De Alencar, Manoelly O. Rocha, Bruno C. Do Couto, Rogério M. De Carvalho, Larissa Magalhães de Almeida Melo, Daniel Júnior Almeida dos Santos, Wendell Karlos Tomazelli ColtroMonitoring nitrite and bisulfite in environmental waters, beverages, and food products is highly relevant due […]Gustavo R. Souza
- The effect of hydrotreating on the pyrolysis oil composition by GC-MS January 2, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01913C, PaperTatiana Bochko, Andrey ShishovThe processing of waste tires is a significant challenge. The pyrolysis of waste tires offers a sustainable pathway to produce fuel, addressing both waste management and energy recovery challenges. However,...The content of this RSS Feed (c) The Royal Society of ChemistryTatiana Bochko
- A Benzothiazole -Based Fluorescent Probe for Hypochlorite -Highly Sensitive Detection and Live -Cell Imaging Research December 30, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01966D, PaperKelong Fang, Xiaozhen Ma, Yuliang JiangHypochlorous acid (HOCl), a key reactive oxygen species, is generated in vivo through the catalytic action of myeloperoxidase and plays a crucial role in innate immunity. However, dysregulation of HOCl...The content of this RSS Feed (c) The Royal Society of ChemistryKelong Fang
- A novel electrochemical sensor for the analysis of vibegron as a newly approved FDA drug: A rational computational design and cleaning validation application December 29, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY02026C, PaperMahmoud A. Tantawy, Zeinab Goda, Suliman Almahmoud, Mina WadieA novel analytical tool was developed for the assay of the recently approved β3-adrenergic receptor agonist “vibegron”. This tool was also utilized for the cleaning validation process, in which the...The content of this RSS Feed (c) The Royal Society of ChemistryMahmoud A. Tantawy
- Selection of a DNA Aptamer for the Development of an Electrochemical Aptasensor for the Detection of Pb²⁺ December 29, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01525A, PaperZiyu He, Dan Wei, Kai Zhou, Changchun Hu, Chao Tang, Shuting Yang, Li Li, Tong Zhou, Yan DengIn order to develop a simple, highly sensitive and cost-effective electrochemical sensor with high specificity for lead ion (Pb2+), a method of modified magnetic beads-systematic evolution of ligands by exponential...The content of […]Ziyu He
- An integrated magnetic–microfluidic chemiluminescence platform for rapid quantification of exosomal miR-21 associated with breast cancer December 29, 2025Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY01842K, PaperSamira Narimani Kohnehshahri, Fatemeh Etezadi, Mohammad Amin Hajari, Abdolah Razi, Mehdi Forouzandeh MoghadamAccurate quantification of microRNAs (miRNAs) is crucial for early cancer diagnosis, but conventional techniques, such as quantitative PCR and microarrays, are time-consuming, costly, and require complex instrumentation.To cite this article before page numbers are assigned, use the […]Samira Narimani Kohnehshahri
- Nanosensors as diagnostic tools: emerging concepts, opportunities, and design barriers December 29, 2025Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY01942G, Critical Review Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Babatunde Olamide Omiyale, Akinola Ogbeyemi, Muhammad Awais Ashraf, Ki-Young Song, Haiyan Yu, Wenjun ZhangThis paper explores various fabrication techniques, advances in material development, and strategies to enhance sensor feedback and responsiveness through the […]Babatunde Olamide Omiyale
- Hypoxia activated fluorescent probe for specific visualization of mitochondrial dysfunction in tumor December 29, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01970B, PaperQilong Zhang, Chun Dai, Huina Wang, Minggang Tian, Zhongwen Zhang, Ruoyao ZhangSelectively monitoring the mitochondrial dysfunction and viability of tumor was an important task for the treatment against cancer, which was helpful for controlling the appropriate radiotherapy and chemotherapy dose to...The content of this RSS Feed (c) The Royal […]Qilong Zhang
- A novel APE1-assisted cycling amplification for rapid and ultrasensitive SERS detection of TK1 mRNA in human serum December 26, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01669J, PaperChangqing Du, Anran Li, Jinye Qiu, Jiarui Sun, Xiaokun Wang, Wei Xu, Maofeng Zhang, Dapeng WangQuantitative mRNA expression levels are essential for differential and clinical diagnoses. In this work, we present an apurinic/apyrimidinic endonuclease 1 (APE1)-assisted SERS sensing platform for rapid and ultrasensitive detection of...The content of this RSS […]Changqing Du
- Measurement of ‘heavy metals’ in particulate matter in outdoor air January 8, 2026
