RSC – Biomater. Sci. latest articles- A Dual-Network Bletilla Striata Polysaccharide Hydrogel for PPAR-Mediated Macrophage Polarization and Accelerated Diabetic Wound Healing January 6, 2026Biomater. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5BM01617G, PaperShan Yu, Ling Wang, Zhenbo Peng, Yanjun Chen, Peifang XuChronic diabetic wounds remain difficult to heal due to persistent inflammation and impaired macrophage polarization. Herein, we developed an immunoregulatory dressing using a hybrid hydrogel (C-B-S) synthesized from natural polysaccharides...The content of this RSS Feed (c) The Royal Society of […]Shan Yu
- Glutathione-Activatable Bola Dendrimers Mediate Tumor-Specific Cytosolic siRNA Delivery via Dynamic Thiol-Disulfide Exchange January 5, 2026Biomater. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5BM01643F, PaperDandan Zhu, Huiling Zhu, Yaoyun Yu, Junyue Zheng, Xianhui Lin, Huimin Cheng, Aoxue Mei, Ming Chen, Yun Li, Haijuan Dong, Jiehua Zhou, Juan Liu, Xiaoxuan (Tracy) LiuEffective delivery of small interfering RNA (siRNA) to the cytosol continues to pose a significant challenge in RNA interference (RNAi)-driven precision cancer therapy. […]Dandan Zhu
- The Rise of cfDNA-Scavenging Nanomaterials for Inflammatory Disease Therapy January 3, 2026Biomater. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5BM01482D, Review ArticleHassan Shah, Zhengkun Liu, Nasrullah Jan, Jiajun He, Huishuang Yin, Weisheng Guo, Kifayat Ullah Shah, Lu Liu, Xing-Jie Liang, Yafang XiaoCell-free DNA (cfDNA), released from damaged cells, acts as a critical danger-associated molecular pattern and plays a key role as a molecular trigger in various inflammatory diseases. Conventional […]Hassan Shah
- A charge-reversal prodrug activated by tumor-acidity for selective cancer chemotherapy January 2, 2026Biomater. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5BM01682G, PaperBing Liu, Guanchun Wang, Quanjun Yang, Yang Yu, Yue Su, Wei Huang, Ping Wang, Deyue Yan, Ping HuangChemotherapy remains a primary cancer treatment. However, the poor selectivity of conventional small-molecule chemotherapeutic agents often leads severe side effects against normal cells and tissues, limiting their clinical application. To...The content of […]Bing Liu
- Advances in lignin and lignin-based composites in biomedical applications January 2, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D5BM01439E, Review ArticleMohamad Nurul Azman Mohammad Taib, Syaiful Osman, Nissa Nurfajrin Solihat, I. Wayan Arnata, Dewi Sartika, Tarique Jamal, Viswanathan S. SajiThe development of biocompatible, biodegradable and mechanically robust materials for biomedical applications remains a major challenge.To cite this article before page numbers are assigned, use the DOI form of […]Mohamad Nurul Azman Mohammad Taib
- Nanotechnology empowering biomedical therapy: new treatment perspectives for sarcopenia and degenerative muscle atrophy January 2, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D5BM01061F, Review ArticleLi Liu, Yiting Cai, Dongcan Liu, Ruiying Fang, Haiqiang Huang, Mi Zou, Bofan Chen, Jie Peng, Liang HaoSarcopenia and muscle atrophy are major health challenges associated with aging and various pathologies, characterized by progressive loss of muscle mass and function.To cite this article before page numbers are assigned, […]Li Liu
- A pH-Ultrasensitive Membranolytic Polymer-Assisted Delivery System for Enhanced siRNA Delivery January 2, 2026Biomater. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5BM01235J, PaperYue Yu, Houbing Zhang, Xian-Zhu Yang, Jun Wang, Menghua Xiong, Xiaojiao DuEndosomal escape is a limiting factor for the in vivo application of nucleic acid therapeutics and remains a major challenge in the development of drug delivery systems. In this study,...The content of this RSS Feed (c) The Royal […]Yue Yu
- Dental plaque biofilm-targeting composite nanomaterials: advances and outlook December 31, 2025Biomater. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5BM01747E, Review ArticleJiaxuan Zhao, Shengyuan Huang, Yongjia Yang, Jilei Wang, Qianqian Guo, Yueming Xu, Bingyin Jiang, Jiang LinThe disruption of oral microbial homeostasis is a major cause of periodontal disease, and the formation of pathogenic plaque biofilms represents a key driver of disease progression. Extracellular polymeric substances...The content of this […]Jiaxuan Zhao
- Dual-Functional Aggregation-Induced Emission Active Chitosan-Based Hydrogel for the Detection and Killing of Pathogenic Bacteria December 30, 2025Biomater. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5BM01805F, PaperAmarjyoti Mondal, Abhay Srivastava, Kusumita Acharya, Palash Jyoti Boruah, Dipak Chamlagai, Alisha Kamra, Arijit Bhattacharya, Subinoy Rana, Atanu Singha RoyCurrent strategies for treating bacterial infections primarily rely on antibiotics, with only limited follow-up monitoring to verify that all bacteria have been eradicated. This limitation has driven research toward the...The […]Amarjyoti Mondal
- Pt(IV) prodrug-gating MOF incorporating copper peroxide and ruthenium complex for NIR-mediated synergistic anticancer therapy December 30, 2025Biomater. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5BM01557J, PaperRomaine Parker, Rajeshkumar Anbazhagan, Chia-Yu Kuo, Teng-Hao ChenThe development of efficient and multifunctional nanosystems is crucial for enhancing anticancer therapy. The incorporation of therapeutic agents in nanocarriers often results in premature drug release, leading to unsatisfactory therapeutic...The content of this RSS Feed (c) The Royal Society of ChemistryRomaine Parker
- Multiple responsive Nano-Prodrug Combining Chemo-Differentiation-Cancer Stem Cells Inhibition toward Triple-Negative Breast Cancer December 29, 2025Biomater. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5BM01254F, PaperYanting Li, Mengdan Ning, Haoping Long, Jiayi Zuo, Jinqiu Liang, Ting Yuan, Feng Cao, Yong Yin, Feng JiangTo overcome therapy resistance driven by breast cancer stem cells (BCSCs) and systemic toxicity of conventional chemotherapy, we engineered a multistimuli-responsive nanoprodrug (DT/PAC@AI NPs) implementing a "chemodifferentiation-cancer stem cells inhibition"...The content of […]Yanting Li
- A Superhydrophilic Zwitterionic Hydrogel Coating for Enhancing Long-Term Anti-bacterial Adhesion and Anti-encrustation Properties of Ureteral Stents December 29, 2025Biomater. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5BM01692D, PaperZhenqing Li, Jiawei Li, Lei Qian, Ye Tian, Haoyu Jin, Peng Yu, Zhengao Wang, Chengyun Ning, Jinxia ZhaiProlonged indwelling of ureteral stents often leads to encrustation, which can cause functional failure and poses a significant clinical challenge. Zwitterionic polymers exhibit excellent anti-fouling performance due to their strong...The content of […]Zhenqing Li
- Simultaneous regeneration of epithelial and bone tissue using a multifunctional film with leaf-stacked structures and growth factors December 19, 2025Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D5BM01644D, PaperHo Yong Kim, Han Byul Kim, Jin-Ho Park, Min Ji Kim, June-Ho Byun, Se Heang OhWe developed a multilayered PCL film integrating a dense barrier layer and leaf-stacked layers loaded with PDGF-BB and BMP-2. This enables sustained growth factor release and cell adhesion, promoting epithelial coverage and bone formation.To […]Ho Yong Kim
- Correction: Optimized synthesis of biphasic calcium phosphate: enhancing bone regeneration with a tailored β-tricalcium phosphate/hydroxyapatite ratio December 19, 2025Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D5BM90098K, Correction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Dieu Linh Tran, Qui Thanh Hoai Ta, Manh Hoang Tran, Thi My Huyen Nguyen, Ngoc Thuy Trang Le, Anh Phuong Nguyen Hong, Hyun-Ji Park, Ki Dong Park, Dai Hai NguyenTo cite this article before […]Dieu Linh Tran
- Beyond polydopamine: expanding the horizon of polycatecholamines for biomaterials and biomedical technologies December 17, 2025Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D5BM01357G, Perspective Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Elena Rainone, Hossam Alshaiba, Fabio VariolaBy comparing emerging polycatecholamines with the well-established polydopamine, this perspective expands the horizon of catecholamine-inspired biomaterials across surface modification, bioadhesive, biosensing and drug-delivery applications.To cite this article before page […]Elena Rainone
- Modulation of the inflammatory microenvironment after SCI to achieve enhanced nerve regeneration using pteryxin-releasing methylacrylated hyaluronic acid December 16, 2025Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D5BM01322D, PaperBaoyang Hu, Bo Sun, Yue Zhao, Chao Chen, Bin Wu, Hongbin Zhang, Bin Liu, Xuejun Yang, Fang FangSchematic showing the modulation of the inflammatory microenvironment after SCI to achieve enhanced nerve regeneration using pteryxin-releasing methylacrylated hyaluronic acid.To cite this article before page numbers are assigned, use the DOI form […]Baoyang Hu
- Bioresorbable-bioactive auxetic “personalised” phalanx with a CT-guided AI-driven model towards in vivo prediction of bone regeneration December 12, 2025Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D5BM01337B, PaperSamir Das, Masud Rana, Radha K. Prabhu, Subhodeep Jana, Nantu Dogra, Kolimi Prashanth Reddy, Amit Roy Chowdhury, Pallab Datta, Ashutosh Bagade, Punit Fulzele, Quazi Zahiruddin, Santanu DharaCT-guided bioresorbable digit reconstruction aims to achieve functional regeneration, with in vitro and in vivo biological assessments.To cite this article before page numbers […]Samir Das
- Nanomaterial-based therapeutic strategies for spinal cord injury repair: harnessing multifunctionality to overcome pathophysiological challenges December 11, 2025Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D5BM01238D, Review ArticleTaile Cheng, Youde Cao, Bing Liang, Kexiao YuSpinal cord injury is a severe central nervous systemdisorder caused by mechanical trauma, leading toirreversible neural damage and secondary neuroinflammation, oxidative stress, and disruption of the blood–spinal cord barrier, result in deficits.To cite this article before page numbers are assigned, use […]Taile Cheng
- Advances in phenylboronic acid and phenylboronic ester-based responsive systems for precision medicine December 10, 2025Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D5BM01624J, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Ratish R. Nair, Loise Råberg, Hanna Mårtensson, Fan Jia, Yifan Gu, Hamza Yakubu, Gizem Erensoy, Alexandra StubeliusPBA and PBE derived materials have played a crucial role in advanced healthcare technologies such as diagnostics, […]Ratish R. Nair
- A versatile bacterial cell wall-based nanomedicine for combination treatment of oral squamous cell carcinoma December 4, 2025Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D5BM01457C, PaperAijing Ma, Chuiyin Wang, Yabo Wang, Gengming Zhang, Zhaoyang Guo, Lei Wu, Xinming Li, Yue Wang, Yinsong Wang, Xiaoying YangA versatile bacterial cell wall (PgCW) extracted from Porphyromonas gingivalis exhibited POD-mimicking, SDT, CDT, and immunoadjuvant performances. PgCW was used to fabricate a nanomedicine for OSCC combination treatment.To cite this […]Aijing Ma
- A Dual-Network Bletilla Striata Polysaccharide Hydrogel for PPAR-Mediated Macrophage Polarization and Accelerated Diabetic Wound Healing January 6, 2026
