RSC – Biomater. Sci. latest articles- Unlocking the potential of extracellular vesicles: One stimulus away from clinical implementation September 29, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM01091H, Review ArticleRicardo M Silva, Vasco D.B. Bonifácio, Sandra Pinto, Ana Azevedo, Carmen Fernandez-BecerraExtracellular vesicles (EVs) are cell-derived, phospholipid bilayer vesicles that hold growing potential in therapeutic applications, as demonstrated by encouraging preclinical and clinical trial results. Despite this potential, translating EV-based therapies...The content of this RSS Feed (c) The […]Ricardo M Silva
- Topologically aligned fibrous biopolymeric hydrogel orchestrates sequential cellular responses for accelerated scarless wound healing September 29, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM00823A, PaperYongjie Wu, Zenghui Jia, Kang Sun, Guangdong Zhou, Ke TaoTopologically aligned fibrous hydrogel orchestrates sequential cellular responses to promote accelerated and scarless wound healing.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of […]Yongjie Wu
- Impact of Material Characteristics on Nanoparticle Penetration and Retention in Thrombi: Implications for Thrombolysis September 28, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM01192B, PaperXiangxun Chen, Haotian Cha, Shehzahdi Moonshi, Nam-Trung Nguyen, Hang Thu TaIschemic cardiovascular disease is the leading cause of death worldwide and is primarily attributed to blood vessel occlusion caused by thrombi. While current treatments and research focus on overall thrombolytic...The content of this RSS Feed (c) The Royal Society […]Xiangxun Chen
- TPP-coated Mo-doped W18O49 biodegradable nanomaterials with mitochondria-targeting and pH-responsive properties for synergistic photothermal therapy/chemodynamic therapy/chemotherapy September 28, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM00833F, PaperYingjuan Ren, Wenhui Yi, Jie Gao, Nan Wang, Di ZhuangSchematic illustration of the fabrication process of TMoWODC and its antitumor mechanism.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of ChemistryYingjuan Ren
- Investigating PolySTAT's role in clot contraction and fibrin network mechanics September 28, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM01101A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Trey J. Pichon, Trevor Corrigan, Melissa Ling, Mishti Dhawan, Anna Tobiasch, Mirjam Bachler, Martin Hermann, Dietmar Fries, Matthew Armstrong, Suzie H. Pun, Nathan J. WhitePolySTAT crosslinks fibrin to strengthen clots and improve force transmission, […]Trey J. Pichon
- Nanomedicine-mediated co-expression of PD-1 blockade and CXCL9 synergizes T cell infiltration and activation in solid tumor September 25, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM01105A, PaperYan Wang, Liang Zhao, Jia-Yu Luo, Jie Li, Xin-Ya Gao, Hui-Xiao Li, Yue Zheng, Jiawei LiuConsiderable progress has been made in cancer immunotherapy with the use of immune checkpoint blockade (ICB). However, its clinical efficacy remains limited due to poor T cell infiltration in solid...The content of this RSS […]Yan Wang
- Development of a decellularized liver matrix-based nanomedicine for metabolic dysfunctionassociated steatotic liver disease September 25, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM01241D, PaperYong-Heng Lin, Huei-Fen Jheng, Yung-Te HouThe incidence of metabolic dysfunction-associated steatotic liver disease (MASLD) has increased, primarily because of excessive nutritional intake and sedentary lifestyles. However, clinical trials investigating therapeutic agents for this condition have...The content of this RSS Feed (c) The Royal Society of ChemistryYong-Heng Lin
- Innovative epidermal-penetrating nanogels with microenvironment-adaptive pH responsiveness orchestrate glucose homeostasis reprogramming and spatiotemporally coordinated therapeutic cascades for precision diabetic wound therapy September 24, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM01175B, PaperXiangli Chen, Jiafan Bai, Linyu Wang, Hongyan Liu, Jie Shi, Wenzhen Peng, Jie Weng, Wei Zhi, Jianxin WangDiabetic wounds are typified by a highly complex pathological microenvironment, marked by hyperglycemia, cellular dysfunction, impaired angiogenesis, and defective tissue regeneration. These factors collectively hinder the normal healing process. In...The content of […]Xiangli Chen
- Fucoidan Based Hydrogel Biomaterials for Tissue Engineering September 23, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00676G, Review ArticleOmanin Siddiqua Prova, Shajia Afrin, Tanveer Tabish, Muhammad RizwanBiopolymer-based biomaterials have gained significant attention in tissue engineering for their ability to support cell adhesion, proliferation, and tissue regeneration. Among these, biomaterials that naturally reduce inflammation, modulate immune responses,...The content of this RSS Feed (c) The Royal Society of […]Omanin Siddiqua Prova
- Charge Modulation in D–A–D Molecules: An Acid-Responsive NIR-II Nanoplatform for Imaging and Photothermal Therapy September 23, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM01084E, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Shu Gao, Jiahui Wang, Xiaonan Wei, Jun Wang, Yuanpeng Jiang, Boyu Tan, Yeshan Qin, Xiaoyang Zhu, Ruihu Song, Chunrong Qu, Kun Qian, Zhen ChengSmall-molecular near-infrared (NIR) dyes have shown high promise in bioimaging and […]Shu Gao
- A multifunctional nanotheranostic: hyaluronic acid-squalene nanoclusters for radiosensitization, ferroptosis, and Mn/Fe-based dual MR imaging September 22, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM00735F, PaperRaveena Nagareddy, Sahil Chahal, Shyam Vasvani, In-Kyu Park, Reju George Thomas, Yong Yeon JeongSHMF nanoclusters synergize radiation therapy and ferroptosis induction, offering a dual therapeutic and imaging platform for enhanced cancer treatment.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of […]Raveena Nagareddy
- Retinal hypoxia reversal with PLGA-oxygen nanobubbles September 22, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM01154J, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Anika Bushra, Wen Ren, Daniel Um, Xiaoxue Han, Michael Tsipursky, Joseph IrudayarajPLGA oxygen nanobubbles were formulated for retinal hypoxia reversal, and ocular safety was ascertained in a rabbit model, indicating promise as an adjuvant […]Anika Bushra
- Bioactive coating with clindamycin, VEGF-165, and TGF-β1 for supporting bone tissue regeneration September 21, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM00637F, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Dagmara Słota, Aleksandra Szwed-Georgiou, Marcin Włodarczyk, Agnieszka Krupa, Karolina Rudnicka, Karina Niziołek, Bartłomiej Kryszak, Konrad Szustakiewicz, Agnieszka Sobczak-KupiecMultifunctional composite coatings combining antibiotics and growth factors for bone tissue regeneration.To cite this article before page […]Dagmara Słota
- Unlocking the therapeutic potential of exosomes for ischemic stroke September 21, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM01007A, Review ArticleMeilin Shen, Yan Zhu, Qi Chen, Huanghao YangIschemic stroke, a leading cause of global mortality and disability, faces therapeutic limitations due to the narrow time window and restricted efficacy of current interventions such as thrombolysis and thrombectomy.To cite this article before page numbers are assigned, use the DOI […]Meilin Shen
- Engineering of soft materials themed collection invitation Likelihood of Polyhydroxyalkanoates Production Using Canola Oil Cake and Specific Bacterial Isolates for Ecofriendly Bioplastics September 19, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00787A, PaperSiddhi Joshi, Mousumi DebnathPolyhydroxyalkanoates (PHA) are suitable replacement to conventional petroleum plastics. The global push for environmentally friendly plastics is driving research into innovative, sustainable solutions. This study emphasizes enhancing the production and...The content of this RSS Feed (c) The Royal Society of ChemistrySiddhi Joshi
- Modulating Oxygen Release via Manipulated Microspheres Embedded in Thermoresponsive Hydrogel for Enhanced Stem Cell Survival under Hypoxia September 18, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00480B, PaperJiyeon Lee, Jisun Kim, Ki Wan Bong, Soo-Chang SongEnsuring a stable oxygen supply for transplanted cells remains a major challenge in the clinical translation of tissue engineering and regenerative medicine. Hypoxic environments caused by insufficient vascularization are a...The content of this RSS Feed (c) The Royal Society of ChemistryJiyeon Lee
- Gd3+-doped carbon dots: modulation of mechanisms regulating gastrointestinal tract motility and the hepatobiliary system September 18, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM01077B, PaperOlga V. Tsymbalyuk, Tamara L. Davydovska, Vladimir Lysenko, Ivan S. Voiteshenko, Konstantin Paliienko, Tatiana A. Borisova, Stanislav P. Veselsky, Alex Y. Nyporko, Olha V. Pylypova, Tetiana O. Fedirko, Anna M. Naumenko, Evelina D. Melenevska, Mariya S. Kozolup, Valeriy A. SkryshevskyAn experimental study of the state of regulation of spontaneous […]Olga V. Tsymbalyuk
- Single-cell encapsulation of mesenchymal stromal cells via ECM-mimetic supramolecular hydrogels enhances therapeutic efficacy September 16, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM01013F, PaperXueting Wei, Jiajia Luo, Xianghua Zhong, Xuebing Tao, Xinyang Liu, Xi Peng, Kunyu Zhang, Peng ShiWe developed a supramolecular hydrogel-based single-cell encapsulation strategy that mimics the dynamic ECM microenvironment, enhancing MSC energy metabolism, stress resistance, and regenerative capacity, thereby improving cardiac repair.To cite this article before page numbers are […]Xueting Wei
- Multifunctional erythromycin-loaded liposomes: a methodological optimization for enhanced mucoadhesion, antioxidant activity, and biocompatibility September 16, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM00629E, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Vera-Maria Platon, Anda Mihaela Craciun, Irina Rosca, Natalia Simionescu, Luminita MarinDevelopment and optimization of erythromycin-loaded nanoliposomes as a versatile delivery platform to treat infections with coexisting bacterial resistance and oxidative stress, especially at mucosal […]Vera-Maria Platon
- An activatable self-amplifying ROS nanoplatform for augmented Cerenkov radiation-induced photodynamic therapy September 16, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM01156F, PaperHehua Xiong, Yiling Ruan, Huihui Liu, Xuan Liu, Xiaolian SunWe reported a tumor acidity-triggered, mitochondria-targeted Cerenkov radiation-photodynamic therapy platform that enhanced ROS generation within mitochondria, resulting in higher mitochondrial dysfunction and enhanced apoptosis in cancer cells.To cite this article before page numbers are assigned, use the DOI form of […]Hehua Xiong
- Unlocking the potential of extracellular vesicles: One stimulus away from clinical implementation September 29, 2025
