RSC – Biomater. Sci. latest articles- Non-Destructive Approaches for Retrieving T-Cells from Fibrous Scaffolds for Therapeutic Applications August 25, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00877H, PaperJaydeep Das, Neil R. Cameron, Prakriti TayaliaFlasks and plates have traditionally been used to culture cells required for cell-based therapies. Recent success of adoptive T-cell transfer therapy (ACT) for various pathological conditions warrants development of more...The content of this RSS Feed (c) The Royal Society of ChemistryJaydeep Das
- Regulation of response to antigen peptides is independent of peptide distribution in lymph node therapeutics August 22, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00328H, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Ryan A. McIlvaine, Senta M. Kapnick, Sean T. Carey, Christopher M. JewellAutoimmune disease occurs when immune cells mistakenly identify specific molecules, termed antigens, on healthy cells. There are no cures for these diseases, and […]Ryan A. McIlvaine
- Revisiting the biophysical aspects of extracellular-matrix–mimicking hydrogels: what cells see vs. what cells feel August 21, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00210A, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Jingchao Sui, Sarah Pragnere, Nicholas A. KurniawanThe extracellular matrix (ECM) is critical in regulating cell behavior and tissue function. This recognition has driven the development of ECM surrogates to better understand cell–ECM interactions […]Jingchao Sui
- Composite Nano Copper Carrier Combined Cuproptosis and Photodynamic Therapy for Spatiotemporal Synergistic Anti-Tumor August 21, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00954E, PaperYongguo Hu, Fang Zhang, Li-Li Chen, Xin-Yue Xu, Pei-Jie Zhang, Yong Li, Jin-Xuan Fan, Jia-Hua Zou, Yuan-Di ZhaoCuproptosis is a copper-dependent programmed cell death triggered by mitochondrial dysfunction, offers significant anti-tumor potential but requires tumor-specific copper delivery to avoid systemic toxicity. Here, we developed a synergistic nanoplatform...The content of […]Yongguo Hu
- A Modular, Nanoscale Platform for the Targeted Delivery of Camptothecin to Cancer Cells Expressing TAG-72 August 20, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00788G, Communication Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Reham Hassan, Zirui Zhu, Mingyang Ji, Ziyuan Meng, Emily R. Matas, Damu Sunilkumar, Dario Palmieri, Benjamin A. Conrad, Thomas J. Magliery, Jon ParquetteA camptothecin (CPT)-dilysine nanotube, stabilized with a layer of polydopamine (PDA), was […]Reham Hassan
- Application of metal-organic frameworks-based reactive oxygen species therapy in cancer August 19, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00791G, Review ArticleHeshi Liu, Xue Wang, Pai Wang, Hongtao Liu, Quan Wang, Caina Xu, Huayu TianReactive oxygen species (ROS) hold significant therapeutic potential in cancer treatment, with metal-organic framework (MOF)-based nanocarriers showing considerable promise for ROS-mediated therapies. This review systematically explored the advantages of MOFs...The content of this RSS Feed […]Heshi Liu
- MRI detection and grading of Knee Osteoarthritis - A pilot study using an AI technique with a novel imaging-based scoring system August 18, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00470E, PaperChandrashish Roy, Mohammed Roshan, Nidhi Goyal, Prerana Rana, Nitin P. Ghonge, Amarnath Jena, Raju Vaishya, Sourabh GhoshPrecise and rapid identification of osteoarthritis (OA) is essential for efficient management and therapy planning. Conventional diagnostic techniques frequently depend on subjective interpretation, which have shortcomings, particularly during the first...The content of this […]Chandrashish Roy
- Ultrasound-Responsive Azide Nano-prodrugs Enable Spatiotemporal Activation of TLR7/8 Agonists for Tumor Therapy August 18, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00755K, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Chuwen Luo, Chaoying Kong, Yuxiao Zhang, Yajun Xu, Zhaohui TangSystemic immunotoxicity caused by off-target activation is still a critical obstacle to clinical translation of imidazoquinoline (IMDQ) drugs, a kind of TLR7/8 agonists. Here, we […]Chuwen Luo
- Synthetic biology-driven design and bioproduction of mechanical proteins August 18, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM00646E, Review ArticleYuqing Wang, Fan Wang, Huijing Cui, Jingjing Li, Hongjie Zhang, Kai LiuThis review summarizes recent advances in the bioproduction of engineered structural proteins and materials, highlighting engineering strategies in hosts, sequences, and cultivation conditions.To cite this article before page numbers are assigned, use the DOI form of citation […]Yuqing Wang
- Polyaspartamide-based antimicrobials for combatting bacterial infections August 17, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM00994D, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Wenlong Zhang, Guowenlie Gao, Yuqian Ji, Mingming Zhao, Pengqi Wan, Chunsheng Xiao, Xuesi ChenA series of cationic polyaspartamides (PASPnDAm) with different side chain lengths (m) and degrees of polymerization (n) were synthesized to systematically […]Wenlong Zhang
- MOF-based nanoagent for self-illuminating photodynamic therapy August 15, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM00963D, PaperJing-Lan Kan, Fan-Hong Lv, Wen-Xiu Ren, Qun Guan, Anqi Xue, Jie Feng, Yu-Bin DongA MOF-based self-illuminating system, which can be a highly efficient photodynamic therapy nanoagent for tumor treatment without an external light source, is reported.To cite this article before page numbers are assigned, use the DOI form of […]Jing-Lan Kan
- pH-Responsive Carrier-Free Nanoparticles Based on Teicoplanin and Borneol for Enhanced MRSA Infectious Wound Healing August 15, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00879D, PaperXin Wang, Shuyang Hu, Ya-nan Fu, Wensheng Xie, Guofeng Li, Dongsheng Kong, Xing WangBacterial infections severely threaten human health, and the drug resistance induced by long-term high-dose antibiotic use is a critical issue, which necessitating new antibacterial strategies. In this study, a pH-responsive...The content of this RSS Feed (c) […]Xin Wang
- Lung-targeting lipid nanoparticle-mediated sparstolonin B delivery improves acute lung injury August 14, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM00590F, PaperQinghe Meng, David O. Popoola, Chunyan Wang, Yuqin Men, Yuqi Song, Zhi Cao, Adam Novak, Yamin Li, Robert N. CooneyA lung-targeted sulfonium lipid nanoparticle (sLNP) formulation of sparstolonin B (SsnB) effectively inhibited inflammation and tissue injury in a murine model of LPS-induced acute lung injury (ALI) following intravenous administration.To […]Qinghe Meng
- Sequentially Unlockable Prodrug Nanoparticles Enable Spatiotemporal Coordination of Chemotherapy and Tumor Microenvironment Regulation for Metastasis Prevention in Breast Cancer August 14, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00865D, PaperZheng Wang, Rui Yang, William Lee Davis, Yanran Xing, Yiwen Fu, Bo Wang, Wanhong Li, Hongliang Qian, Liqing Gao, Dechun Huang, Yinan Zhong, Wei ChenChemotherapy remains the cornerstone in the clinical management of metastatic cancer, aiming at the tumor cells. However, its therapeutic efficacy is significantly hampered by poor […]Zheng Wang
- Ga3+-doped coenzyme-based adhesives for periodontitis treatment August 14, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM01096A, PaperYing Qi, Jing Zheng, Qian Zhang, Yage Sun, Jiaxing Shao, Hongying Wang, Rong Yang, Ziyang Xu, Chunyan Cui, Wenguang LiuChronic periodontitis is a long-standing thorny issue for oral health, characterized primarily by the excessive production and accumulation of reactive oxygen species, pathogenic bacterial infection, and the continuous loss of...The […]Ying Qi
- NIR-Activatable Aza-BODIPY Nanoparticles for Photoacoustic Imaging and Synergistic NO–Photothermal Cancer Therapy August 13, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00937E, PaperJunjie Li, Qian He, Jiawen He, Panyue Wen, Haochen Guo, Masaru Tanaka, Shizhong Luo, Ye Liu, Wen Liewei, Chenzhi YaoNear-infrared (NIR) photothermal therapy (PTT) has emerged as a promising modality for cancer treatment due to its minimal invasiveness, precise spatiotemporal control, and potent therapeutic outcomes. However, the clinical application...The […]Junjie Li
- Real-time monitoring of mitochondrial temperature and calcium spikes using fluorescent organic probes August 12, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00691K, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Mengnan Sun, Bo Chen, Aiguo WuAstrocytes, the abundant glial cells, maintain cerebral homeostasis and cognitive functions through calcium signalling-a regulatory pathway that is frequently altered in brain disease. Mitochondria serve as thermal hubs in […]Mengnan Sun
- Polyaspartic Acid Coatings for Blood-Contacting Medical Devices: Antithrombotic and Antibacterial Properties under Static and Dynamic Conditions August 12, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D4BM01714E, PaperCuong Hung Luu, Dimple Sajin, Hoang Huy Vu, Nhat-Khuong Nguyen, Nam-Trung Nguyen, Hang Thu TaThe increasing use of blood-contact medical devices has brought about significant advancements in patient care, yet it also presents challenges such as thrombus formation and infection risks. Surface coatings play...The content of this RSS Feed […]Cuong Hung Luu
- NiFe-LDH-Enhanced Ru Single-Atom Catalysts Anchored on MXene for Synergistic Photothermal-Nanocatalytic Cancer Therapy August 12, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM01060H, PaperSharipova Gulnihol, Takhirov Yuldash, Rakhmanov Kosim, Avliyoqulova Musharraf, Lola Abduraximova, Zukhra Ismailova, Ibragimkhodjaev Bakhodir, Kuchkorova Ra'no, Abdullayev Dadaxon, Dilbar Urazbaeva, Sullieva Suluv, Monireh FarajiSingle-atom catalysts (SACs) have emerged as revolutionary agents in cancer treatment owing to their optimized atomic efficiency and highly tunable catalytic properties. Nonetheless, their clinical application […]Sharipova Gulnihol
- Seeing deep to map cell–biomaterial interactions via whole mount light sheet imaging and automated analytics in decellularized extracellular matrix models August 12, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM00630A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Oscar R. Benavides, Sabrina N. VandenHeuvel, Sanjana Roy, Brinlee Goggans, Shubha Holla, Varsha Rajavel, Joseph Duran, Lucia L. Nash, Daniel L. Alge, Alex J. Walsh, Shreya A. RaghavanAn optical clearing, light sheet microscopy and […]Oscar R. Benavides
- Non-Destructive Approaches for Retrieving T-Cells from Fibrous Scaffolds for Therapeutic Applications August 25, 2025
