RSC – Biomater. Sci. latest articles- Melatonin and the nervous system: Nanomedicine perspectives March 28, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D4BM01609B, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Fucen Luo, Yuru Deng, Borislav Angelov, Angelina AngelovaThe mechanism of action of melatonin on the nervous system, sleep, cognitive deficits, and aging is not fully understood. Neurodegenerative diseases (ND) are one of the […]Fucen Luo
- Long-term interleukin-4 release from 3D printable affinity hydrogels promotes M2-like macrophage polarisation in vitro March 28, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D4BM01623H, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.George A. Loxley, Consuelo Coser, Amir M. Ghaemmaghami, Jing YangLocalised cytokine delivery is a promising strategy for modulating immune response and enhancing regenerative medicine therapies. SPAK-PEGDA hydrogels enable the long-term controlled release of lysozyme […]George A. Loxley
- Supervised Machine Learning for Predicting Drug Release from Acetalated Dextran Nanofibers March 28, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00259A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Ryan Woodring, Elizabeth Graham-Gurysh, Tanvi Pulipaka, Kevin Shilling, Rebeca T. Stiepel, Erik S. Pena, Eric M Bachelder, Kristy AinslieElectrospun drug-loaded polymeric nanofibers can improve the efficacy of therapeutics for a variety of implications. By […]Ryan Woodring
- OBOC screening high activity and low-toxic polymyxin analogs against MCR-1 resistance strain March 27, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00362H, CommunicationWenhong Zheng, Xin Wang, Hao Lian, Pengfei Zou, Tongyi Sun, Hao Wang, Li-Li LiWe performed inverse synthesis to create 1,152 structurally analogs of polymyxin B with modified hydrophilicity and charge properties using OBOC technology. This led to the identification of two promising candidates...The content of this RSS Feed (c) […]Wenhong Zheng
- Pyroptosis-preconditioned mesenchymal stromal cell-derived extracellular vesicles as advanced nanomedicines for treating inflammatory diseases March 27, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D4BM01505C, PaperQianyi Wu, Shuyun Liu, Meng Zhao, Yizhuo Wang, Ke Lv, Jiaying Zhu, Jingping LiuUncontrolled inflammation is one of the major causes of various forms of tissue injury, and nanomedicines with immunoregulatory effects are needed. Mesenchymal stromal cell-derived extracellular vesicles (e.g., MSC-EVs) have been...The content of this RSS Feed (c) […]Qianyi Wu
- Biomimetic organomineral layers with antibacterial properties based on di/tetrahydroquinolinediol and nanocrystalline hydroxyapatite deposited on enamel surface March 27, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM00070J, PaperPavel Seredin, Dmitry Goloshchapov, Yaroslav Peshkov, Andrey Potapov, Yana Gribanova, Khidmet Shikhaliev, Yury Ippolitov, Raul O. Freitas, Iman A. Mahdy, Manal A. Mahdy, Boknam ChaeThe paper proposes a strategy for the accelerated deposition of biomimetic organomineral layers on the surface of dental enamel, utilizing dihydroxyquinoline polymerized in the presence […]Pavel Seredin
- Advances in the Application of Hydrogel Adhesives for Wound Closure and Repair in Abdominal Digestive Organs March 27, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00093A, Review ArticleZhen Wang, Zhen Zhang, Chaoliang He, Quan WangThe abdominal cavity houses the majority of the digestive system organs, which frequently suffer from diseases with limited responsiveness to pharmacological treatments, such as bleeding, perforation, cancer, and mechanical obstruction....The content of this RSS Feed (c) The Royal Society of ChemistryZhen Wang
- Natural product-integrated microneedle patch for rheumatoid arthritis treatment through anti-inflammation and angiogenesis suppression March 27, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM00036J, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Peng Hua, Suleixin Yang, Lin Yu, Yongzhuo Huang, Meiwan ChenA microneedle patch (B/S-TM@MN) was developed to encapsulate ROS-responsive micelles loaded with berberine and sinomenine, which enhanced the overall anti-arthritis outcome through simultaneous anti-inflammation and […]Peng Hua
- GalNAc-Functionalized Metal-Organic Frameworks for Targeted siRNA Delivery: Enhancing Survivin Silencing in Hepatocellular Carcinoma March 26, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00363F, PaperXiuyan Wan, Yingli Ge, Wanqi Zhu, Jie Zhang, Wei Pan, Na Li, Bo TangSmall interfering RNA (siRNA) is a potent method for silencing survivin mRNA within cells, offering a promising option for treating hepatocellular carcinoma (HCC) since survivin is specifically overexpressed in HCC...The content of this RSS Feed (c) […]Xiuyan Wan
- Harnessing nanoparticles and bioorthogonal chemistries for improving precision of nuclear medicine March 26, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D4BM01387E, Review ArticleGayathri R. Ediriweera, Mengdie Li, Nicholas L. Fletcher, Zachary H. Houston, Muneer Ahamed, Idriss Blakey, Kristofer J. ThurechtNanotechnology combined with bioorthogonal approaches provides unique routes to improving nuclear medicine imaging and therapy, opening up new avenues to treat many different diseases.To cite this article before page numbers are […]Gayathri R. Ediriweera
- A light-activated Fe2+ release nanosystem for enhanced chemodynamic/chemo therapy via cascade amplification of ROS generation March 26, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D4BM01425A, PaperWei Guo, Min Wang, Xisha Chen, Mei Wang, Yingcai MengFerrous iron (Fe2+)-based chemodynamic therapy (CDT) shows great potential for improving chemotherapeutic efficacy and reducing side effects. However, the spontaneous oxidation and biological matrixes can influence the catalytic ROS generation...The content of this RSS Feed (c) The Royal Society of […]Wei Guo
- Controlling stimulus sensitivity by tailoring nanoparticle core hydrophobicity March 26, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM00163C, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Xiao Zhang, Bowen Zhao, Shiwei Fu, Ronald S. Seruya, Hannah E. Fanos, Ashley A. Petrisor, Yilin Liu, Zixin Yang, Fuwu ZhangThis study introduces a novel and efficient approach for constructing stimulus-responsive polycarbonates with tunable […]Xiao Zhang
- Acid responsive molybdenum (Mo)-based nanoparticles inhibit the cGAS-STING signaling pathway for sepsis therapy March 25, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM00007F, PaperXinyu Wang, Qingbin He, Lining Wang, Chengzhilin Li, Wenyu Zhang, Zhonghou Rong, Qingqing Yin, Yingchun ZhaoThis study proposes a multi-target strategy to combat sepsis by eliminating ROS and suppressing cGAS-STING pathway activation, the approach mitigates cytokine storms and sepsis-induced organ failure.To cite this article before page numbers are assigned, […]Xinyu Wang
- Selenium-vacancy-mediated NiCoSe nanoplatforms with NIR-II amplified nanozyme for Methicillin-resistant Staphylococcus aureus-infected pneumonia† March 25, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00188A, PaperLiqin Wu, Lida Jin, Xintong Zou, Xiaojun He, Yuanrong Dai, Jianan HuangThe clinical management of bacterial pneumonia (BP) induced by multidrug-resistant (MDR) pathogens poses substantial therapeutic challenges, necessitating urgent development of novel antibacterial agents and treatment paradigms, particularly those targeting deep-tissue...The content of this RSS Feed (c) The Royal […]Liqin Wu
- Multifunctional biomimetic liposomal nucleic acid scavengers inhibit the growth and metastasis of breast cancer March 24, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D4BM01721H, PaperYuhang Miao, Kaizhen Wang, Xin Liu, Xin Wang, Yanwei Hu, Zhenwei Yuan, Dawei DengLipo-Rh2 multifunctional bionic lipid nucleic acid scavenger can inhibit tumor progression and suppress tumor metastasis by clearing cfDNA. The embedded ginsenoside Rh2 serves as both a structural stabilizer and a targeting ligand.To cite this article before […]Yuhang Miao
- Electrical hydrogel: electrophysiological-based strategy for wound healing March 21, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D4BM01734J, Review ArticleXingan Qiu, Feng Xiang, Hong Liu, Fangbiao Zhan, Xuezhe Liu, Pengzhen Bu, Bikun Zhou, Qiaojian Duan, Ming Ji, Qian FengThe applications of electrical hydrogels in the healing of various types of wounds, including acute traumatic wounds, chronic infected wounds, chronic diabetic wounds, and chronic burn wounds.To cite this […]Xingan Qiu
- Polydopamine as a versatile optical indicator for colorimetric and fluorescence-based biosensing March 20, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM00084J, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jena Subhra Sulipta, Haejin Jeong, Seonki HongThis review provides a comprehensive overview of the advancements in the use of polydopamine-based materials for colorimetric and fluorescence-based biosensing.To cite this article before page numbers are […]Jena Subhra Sulipta
- Micro/nanomotors for Active Inflammatory Diseases Therapy March 20, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00052A, Review ArticleXue Yang, Lishan Zhang, Hui Ran, Fei Peng, Yingfeng TuInflammation is a carefully orchestrated response of immune system to repair the injured tissues and clear various damage factors. However, dysregulated inflammation can eventually contribute to the development and progression...The content of this RSS Feed (c) The Royal Society […]Xue Yang
- Localized and sustained delivery of indomethacin using poly(lactic-co-glycolic acid)-based microspheres to prevent traumatic heterotopic ossification March 20, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D4BM01719F, PaperJunmin Shen, Ti Zhang, Junyu Chen, Feifan Chang, Liming Yang, Zhikang Guo, Ruijing Chen, Penghao Liu, Ni Jiang, Yajun XieIndomethacin-loaded PLGA microspheres (30% drug loading) effectively inhibit traumatic heterotopic ossification. Their controlled degradation and localized drug release provide a promising therapeutic strategy for THO prevention.To cite this article before […]Junmin Shen
- Tumor signal amplification and immune decoy strategy using bacterial membrane-coated nanoparticles for immunotherapy March 19, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D4BM01535E, PaperYifan Li, Weiwei Wang, Jiale Xu, Bei Zhao, Longying Xiong, Dan Ge, Yanping Wu, Xiaotan Dou, Yuping Fu, Lei Wang, Cheng Zhao, Min ChenThe prepared magnetic nanoparticles wrapped in bacterial membranes can promote immunogenic cell death and recruit immune cells to kill tumors.To cite this article before page numbers […]Yifan Li
- Melatonin and the nervous system: Nanomedicine perspectives March 28, 2025
