RSC – Biomater. Sci. latest articles- In situ induction of multivalent PD-L1 antibody secretion to enhance cancer immunotherapy February 12, 2026Biomater. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5BM01896J, PaperLi-Li Chen, Shi-Kun Zhou, Shui-Qing Jiang, Yi-Qun Sun, Xin-Yu Tan, Yi-Fang Chen, Yang Liu, Zi-Dong Lu, Cong-Fei XuImmune checkpoint blockade (ICB) therapy has transformed cancer treatment; however, its therapeutic efficacy remains limited, largely due to insufficient intratumoral accumulation of checkpoint-blocking antibodies (e.g., anti-PD-L1) and suboptimal immune activation....The content of […]Li-Li Chen
- Amphiphilic Guanidine-based Lipids Enhance mRNA Delivery and Immune Activation February 12, 2026Biomater. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6BM00068A, PaperQi Wei, Ruoshui Li, Jiaqi Fan, Mengyuan Xu, Pengcheng Yuan, Jiwei Liu, Qian Wang, Youqing Shen, Nigel K. H. Slater, Jianbin TangLipid nanoparticles (LNPs) have emerged as a promising platform for mRNA delivery with widespread applications across various fields, including gene editing, disease treatment, and vaccine development. Improving mRNA […]Qi Wei
- Acidic pH-triggered AIE nanoparticles covalently cross-linking for enhanced tumor imaging and photodynamic therapy February 12, 2026Biomater. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5BM01655J, PaperWeiqi Zai, Huiling Ji, Jincheng Li, Jing Wang, Hongli Chen, Dan Ding, Shenglu Ji, Nannan WangThe therapeutic effect of tumors heavily relies on the accumulation and retention of nanomaterials at the tumor site. In here, we developed two acidic pH-responsive protonated PCL-PAE-DBCO and PCL-PAE-N3 polymers,...The content of this RSS […]Weiqi Zai
- Investigation of nanoscale topography and biomechanical tuning of PDMS substrates to enhance cardiomyocyte differentiation from human induced pluripotent stem cells February 12, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D5BM01840D, PaperFatemeh Etezadi, Mohammad Ali Shokrgozar, Shahin Bonakdar, Kentaro Hayashi, Daniel M. Packwood, Motomu Tanaka, Kouichi HasegawaPDMS is still the most widely used biomaterial for bioengineering studies, which can mimic the tissue stiffness and micro/nanostructure to improve the generation and investigation of iCM differentiation from hiPSCs.To cite this article before […]Fatemeh Etezadi
- Editorial for the ESB 2025 collection February 12, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D6BM90004F, EditorialSilvia Farè, Gianluca Ciardelli, Nicholas J. Dunne, Maria E. SouthallSilvia Farè, Gianluca Ciardelli, Nicholas J. Dunne and Maria E. Southall introduce the Biomaterials Science themed European Society for Biomaterials (ESB) 2025 collection.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of […]Silvia Farè
- New progress in hydrogen-synergistic diagnostic and therapeutic nanoplatforms for tumor treatment February 5, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D5BM01802A, Review ArticleMingkang Shi, Yu Duan, Jiawen Sun, Mengyao Li, Yaxin Wu, Wenbo Zhao, Chun MaoThis review details hydrogen nanomaterial design, synergistic nanoplatform assembly, anticancer advantages, multiple synergistic tumor treatment mechanisms, and effects of hydrogen-based synergistic therapy.To cite this article before page numbers are assigned, use the DOI form of […]Mingkang Shi
- Silver Nanoclusters with Near-Infrared-II Emission: Synthesis, Properties, and Biomedical Applications February 4, 2026Biomater. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5BM01870F, Review ArticleZhiming Deng, Jiayou Tao, Yao Huang, Xingwang WenOptical imaging is playing an increasingly critical role in modern biomedical research. In particular, the second near-infrared window (NIR-II, 1000-1700 nm) has attracted widespread attention due to its significant advantages...The content of this RSS Feed (c) The Royal Society of ChemistryZhiming Deng
- tPLGA nanoparticles combined with CCL2/CCR2 inhibitor mitigate post-thrombolytic hemorrhagic transformation February 3, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D5BM01807B, PaperFeiyang Luo, Jingmei Pan, Zhenhua Wang, Che Qing, Xi Xiao, Xing Guo, Shaobing ZhouAn MMP-9-responsive tPLGA nanoplatform enables spatiotemporally controlled tPA delivery for targeted thrombolysis. Coupling with CCL2/CCR2 inhibition suppresses neuroinflammation, preserves BBB integrity, and prevents hemorrhagic transformation.To cite this article before page numbers are assigned, use the DOI […]Feiyang Luo
- Piezostimulation using ultrasound-active poly-L-lactide films: The effects of a ZnO filler and cold atmospheric plasma surface treatment February 3, 2026Biomater. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5BM01497B, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Spela Stor, Martina Žabčić, Lea Gazvoda, Masoumeh Sepideh Salehidashtbayaz, Ita Junkar, Tina Radosevic, Matejka Podlogar, Martin Šala, Matjaz Spreitzer, Marija VukomanovićPiezostimulation has the potential to promote human cell growth while inhibiting bacterial growth. Antimicrobial […]Spela Stor
- Correction: Ciprofloxacin-loaded bioadhesive hydrogels for ocular applications February 2, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D5BM90097B, Correction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Islam A. Khalil, Bahram Saleh, Dina M. Ibrahim, Clotilde Jumelle, Ann Yung, Reza Dana, Nasim AnnabiTo cite this article before page numbers are assigned, use the DOI form of citation above.The content of this […]Islam A. Khalil
- Self-enhanced multifunctional nanoplatforms for tumor-specific synergistic therapy via NIR-induced mild photothermal and chemodynamic effects February 2, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D5BM01539A, PaperXi Zhang, Zhiping Song, Yu Han, Jingtong An, Qishan Xu, Xiangyan Chen, Yantao LiThe construction of multifunctional cascade nanoplatforms overcomes the inherent limitations of combined mPTT and CDT, thereby amplifying tumor-specific therapeutic efficacy.To cite this article before page numbers are assigned, use the DOI form of citation above.The content […]Xi Zhang
- Antioxidant Nanozymes for Periodontal Bone Regeneration: Multifunctional Mechanisms and Therapeutic Applications February 2, 2026Biomater. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5BM01548K, Review ArticleXiaoyi Liu, Ruixue Cheng, Yan Huang, Li Chen, Maolin Li, Ying Xia, Lan Huang, Qi Liu, Kun YangThe regeneration of bone defects in periodontitis remains a significant clinical challenge due to the complex and dynamic pathological microenvironment. The primary barrier stems from a self-perpetuating cycle driven by...The content […]Xiaoyi Liu
- Injectable self-healing oxidized pectin and carbohydrazide-modified gelatin hydrogels for curcumin-loaded zein nanoparticle delivery in antioxidant therapy January 30, 2026Biomater. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5BM01302J, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Francesca Tivano, Elena Marcello, Camilla Paoletti, Alice Zoso, Clara Mattu, Irene Carmagnola, Valeria ChionoThe design of drug delivery systems (DDS) for efficient and sustained in situ antioxidant treatment is demanded in regenerative medicine applications. […]Francesca Tivano
- An ROS-responsive antioxidant hydrogel with immunomodulatory activity for promoting diabetic wound healing January 30, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D6BM00018E, PaperYurao Liu, Qianqian Yang, Ling Zhang, Qiyue Lu, Yuhang Li, Haisong Zhang, Chunfang Zhang, Pingli WuAn ROS-responsive hydrogel was developed. The hydrogel exerts immunomodulatory effects by scavenging ROS. It regulates PPAR, PI3K-AKT, and JAK-STAT signaling pathways for pro-regeneration. This hydrogel represents an ideal diabetic wound dressing.To cite this article […]Yurao Liu
- Synergistic pharmacotherapy for epilepsy: NPY (3–36)-modified ZIF-90 nanoparticles co-delivering GW2580 January 30, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D5BM01868D, PaperPeipei Cao, Chao Geng, Xinghui Ren, Xiaoqi Chu, Yiting Zhai, Wenyou Li, Changxin WuMechanisms underlying NPY@ZIF-RG synergistic pharmacotherapy for epilepsy.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of ChemistryPeipei Cao
- Oxygen carriers: core strategies for modulating hypoxic microenvironments and promoting healing in chronic wounds January 29, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D5BM01572C, Review ArticleMeilin Liu, Yuzhi Chen, Kai Zhu, Shiyu Tao, Yao Xiao, Lian Zhao, Lianju MaThis review summarizes oxygen carriers based on perfluorocarbons and hemoglobin for chronic wound therapy, compares their O2 delivery capacities, analyzes synergistic biological effects, and describes challenges in clinical translation.To cite this article before page numbers […]Meilin Liu
- Chemical engineering strategies to enhance mRNA–LNP stability for therapeutic applications January 27, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D5BM01635E, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Ze Zhang, Yen Hui Ong, Bowei Yang, Bangda Fan, Yi Yan Yang, Qianqian NiThis review highlights chemical engineering approaches for enhancing the in vivo stability of mRNA–LNP, including sequence engineering, chemical modification, structural […]Ze Zhang
- Calotropis procera flower extracts: a green approach to zinc oxide with a pineapple-like nanoleaf morphology for biological applications January 26, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D5BM00929D, PaperKaruvelan Murugan, Udayadasan Sathiskumar, Rajakannu Subashini, Ramachandran Chelliah, Govindasamy Hariharan, Mohan Vedhanayagam, Narasimman SelvakumarWater contamination can trigger Escherichia coli (E. coli) infections, which are extremely harmful to humans.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) […]Karuvelan Murugan
- Injectable crosslinked recombinant collagen nanofiber implants enable robust regenerative repair of photoaged skin January 26, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D5BM01715G, PaperNannan Wei, Yuchen Zhang, Xinyu Tian, Linyan Yao, Jianxi XiaoAn injectable THPC-crosslinked recombinant collagen nanofiber implant enables durable ECM reconstruction and effective repair of UV-induced photoaged skin.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The […]Nannan Wei
- Translational roadmap of BBB-targeted nanoparticle strategies for neuroregenerative therapy in neurodegenerative diseases January 24, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D5BM01582K, Perspective Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Sohui Lee, Jiyeon Lee, Kangwon LeeWe present a translational roadmap for BBB-crossing nanomedicines, integrating transporter-, receptor-, and adsorptive-mediated pathways with disease-specific neuroregenerative demands.To cite this article before page numbers are assigned, use the DOI […]Sohui Lee
- In situ induction of multivalent PD-L1 antibody secretion to enhance cancer immunotherapy February 12, 2026
