RSC – Biomater. Sci. latest articles
- Engineered PD-L1 Nanoregulators for Enhanced Tumor Immunotherapy Tháng 7 11, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00748H, Review ArticleInam Muhammad, Ke Ren, Bowen Shen, Fangyu Zhou, Liya Tian, Jie Liu, Xiao SunProgram death ligand 1 (PD-L1) pathway plays a central role in enabling tumors to escape immune detection, making it a prime target for cancer immunotherapy. While immune checkpoint inhibitors (ICIs)...The content of this RSS Feed […]Inam Muhammad
- 3D printed bioceramic scaffolds with fully interconnected channel networks for enhanced vascularized bone regeneration Tháng 7 10, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00824G, PaperTao Zhang, Lifei Huang, Xiaonan Zhang, Jiali Guo, Yunming Shen, Yongxiang LuoBioceramics have emerged as one of the most widely utilized and promising biomaterials for bone repair. The structural morphology of bioceramic scaffolds plays a critical role in determining their overall...The content of this RSS Feed (c) The Royal […]Tao Zhang
- 4D-Printed Multifunctional Hydrogels as Flexible Strain Sensors and Nerve Conduits Tháng 7 10, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00166H, PaperAkshat Joshi, Saswat Choudhury, Arabinda Majhi, Vageesh Singh Baghel, Sampath Parasuram, Samrat Chauhan, Supriya Khanra, Deprupa Lahiri, Kaushik ChatterjeeConducting hydrogels are critical for advanced bioelectronics and the repair of electroactive tissues. However, developing conducting hydrogels into complex biomimetic shapes with good flexibility and bioactivity poses a major biofabrication...The content […]Akshat Joshi
- Structure-optimized poly(α-amino acid)-based antimicrobial peptide mimetics with balanced bactericidal activity and biosafety for MRSA peritonitis therapy Tháng 7 10, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM00785B, PaperHongfei Sun, Guifeng An, Sarula Bao, Wenbo Du, Ya Su, Dezhi Sun, Xiaohui ZhangDeveloping novel antimicrobial peptide (AMP) mimetics is a crucial approach to addressing the growing problem of bacterial resistance by inheriting the antibacterial advantages of AMPs while overcoming their inherent limitations.To cite this article before page numbers […]Hongfei Sun
- A dual-targeted nano-system co-regulating macrophage ROS and fibroblast ferroptosis for rheumatoid arthritis treatment Tháng 7 9, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM00618J, PaperXiaohua Wang, Tingting Gao, Jingjing Wu, Xu Zhou, Yuanyuan Chu, Lei Zhang, Xi CaoSchematic illustration of the preparation process and therapeutic mechanism of Hep-Lips/CLT.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of […]Xiaohua Wang
- Evaluation of anticoagulant activity and safety of PMPC-PSSS and PMPC-PVBTAC block copolymers Tháng 7 9, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00406C, PaperJustyna Swieton, Thu Thao Pham, Anna Gromotowicz-Poplawska, Krzysztof Szczubiałka, Dariusz Pawlak, Andrzej Mogielnicki, Shinichi Yusa, Bartlomiej KalaskaUnfractionated heparin (UFH) remains a widely used anticoagulant; however, its use is associated with several limitations, including an elevated risk of bleeding, the potential for heparin-induced thrombocytopenia, and the necessity...The content of this […]Justyna Swieton
- Multifunctional Bilayer Dressings: A Next Generation Biomaterial for Enhanced Wound Healing Tháng 7 9, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00095E, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Dimpy Bhardwaj, Saurav Kumar, Garima AgrawalWound healing poses a considerable challenge in the healthcare sector, especially for chronic and infected wounds, requiring advanced technological alternatives that surpass conventional dressings. Bilayer dressings, which combine […]Dimpy Bhardwaj
- A pH-responsive nanoplatform enhancing tumor therapy via calcium overload-induced oxidative stress to potentiate phototherapy and chemotherapy Tháng 7 9, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM00599J, PaperShanshan Fan, Shengsheng Cui, Xinni Pan, Haisong Tan, Cheng Cao, Yueqi Zhu, Yanlei LiuA pH-responsive nanoplatform (Fe3O4/CaCO3-CSL/ICG) enables tumor-targeted Ca2+ release, mitochondrial apoptosis, and synergistic photothermal, photodynamic, and chemotherapeutic effects.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS […]Shanshan Fan
- Microencapsulation system for scalable differentiation of peripheral motor neurons from human induced pluripotent stem cells Tháng 7 9, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00535C, PaperSuel-Kee Kim, Choong Kim, Hyo Won Moon, Jiyou Han, Seong Woo Choi, So Hyang Park, Ha Eun Kim, Byung-Ok Choi, Ji Yoon Kang, Jong-Hoon Kim, Jong Hyun KimStem cell-derived neural cells hold great potential for treating neurological disorders, but clinical translation is limited by the need for scalable, consistent, […]Suel-Kee Kim
- Nanotechnological Approaches for the Targeted Delivery of CRISPR-Cas Systems for Genomic Modifications, Biomolecular Sensing, and Precision Medicine Tháng 7 7, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00711A, Review ArticleMirza Muhammad Faran Ashraf Baig, Wai Tong Chien, Sek Ying ChairHere, we explored an innovative integration of nano-approaches and the components of the “clustered regularly interspaced short palindromic repeats” (CRISPR) systems. The components of CRISPR-Cas systems, such as Cas enzymes/proteins...The content of this RSS Feed (c) The Royal […]Mirza Muhammad Faran Ashraf Baig
- Macrophage-targeted emodin nanomaterials for effective acute pancreatitis treatment via modulation of the JNK pathway Tháng 7 6, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM00018A, PaperLiying Wang, Mengxiang Tian, Bingzhi Dong, Weiqi Li, Liang Shi, Yifan Tong, Wei Chen, Xin Yu, Hongxia Xu, Bo Shen, Hong YuWe developed a heparin-modified emodin carrier (HEZ) that targets inflamed pancreatic tissue via CD44-mediated macrophage activation. HEZ restored mitochondrial function and reduced oxidative stress by blocking the JNK […]Liying Wang
- Multivalent 2D- and 3D-nanogels as carbohydrate-lectin binders Tháng 7 6, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM00286A, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Ann-Cathrin Schmitt, Maximilian Braun, Stefanie Wedepohl, Mathias Dimde, Philip Nickl, Kai Ludwig, Tatyana L. Povolotsky, Rainer HaagThe development of synthetic glycoarchitectures for targeted bacterial adhesion represents a promising strategy in anti-adhesion therapy.To cite this […]Ann-Cathrin Schmitt
- Injectable Hybrid-Hydrogel Mediated Calcium-Sensing Receptor (CaSR) Activation for Enhanced Osteogenesis and Bone Remodeling Tháng 7 3, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00349K, PaperGrace Felciya Sekar Jeyakumar, Poornima Velswamy, Deebasuganya Gunasekaran, Alexandar Vincent Paulraj, Nivethitha Panneerselvam Manimegalai, Uma Tirichurapalli SivagnanamInjectable hydrogels have transfigured bone tissue engineering by offering minimally invasive solutions for treating irregularly shaped critical-size bone defects. Unlike traditional fixed-shaped bone grafts that require invasive surgeries and precise...The content of this […]Grace Felciya Sekar Jeyakumar
- Scaffold stiffness affects oligodendrocyte proliferation via cell traction forces Tháng 7 1, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM00689A, PaperHaruki Watanabe, Akiko Uyeda, Lili Quan, Shogo Iwai, Ze Zhang, Shinjiro Umezu, Tatsunori Suzuki, Rieko MuramatsuOligodendrocytes, key cells in neural circuit regeneration, alter their behavior and gene expression in response to substrate stiffness. These changes are associated with the traction forces the cells exert in reaction to mechanical cues.To […]Haruki Watanabe
- Lipid-based Polymeric Biomaterial-mediated ex vivo Natural Killer Cell Surface Engineering Tháng 7 1, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00692A, Review ArticleJaewon Park, Kyung Mu Noh, Kyobum KimNatural killer (NK) cell-based immunotherapy has gained significant attention due to its ability to selectively recognize and eliminate cancer cell through immunological synapses formation while sparing normal cells. However, the...The content of this RSS Feed (c) The Royal Society of ChemistryJaewon Park
- Impact of culture vessel materials on biomanufacturing of dendritic cell-based immunotherapies in closed systems Tháng 6 30, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM00245A, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Jiyu Jessica Tian, Hamid Ebrahimi Orimi, Natalie Fekete, Nicolas Drolet, Katie Campbell, Michel L. Tremblay, Linda Peltier, Pierre Laneuville, Pierre-Luc Girard-Lauriault, Corinne A. HoesliThis review presents a multifaceted overview of how the biomanufacturing […]Jiyu Jessica Tian
- Magnetically actuated superparamagnetic liposomes for accurate photothermal therapy and in situ antitumor immunoactivation Tháng 6 30, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM00279F, PaperHan Gong, Aiqing Ma, Jiacheng Ouyang, Rui Hao, Shichao Zhang, Wei QiuMagnetically guided SPION-liposomes (Lipo-IONs) enable ligand-free tumor targeting. NIR-induced photothermal/ROS effects trigger cancer cell apoptosis and M1 macrophage polarization, synergistically enhancing antitumor efficacy.To cite this article before page numbers are assigned, use the DOI form of citation above.The […]Han Gong
- Combined sustained and triggered release for sequential viral-transduction from collagen-based scaffolds for tissue regeneration Tháng 6 26, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D5BM00623F, PaperJohn J. Amante, Bridget Twombly, Naaz Thotathil, Cathal J. KearneyIndividually-triggered pockets within a regenerative collagen scaffold enable sequential release of therapeutic genes to direct tissue repair.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal […]John J. Amante
- Indocyanine Green-based nanomedicine for Theranostic Applications Tháng 6 26, 2025Biomater. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5BM00670H, Review ArticleJinghang Li, Shuangyu Tian, Xi Zhang, Xinyang Deng, Haixing Xu, Lesan YanIndocyanine green (ICG), a near-infrared (NIR) fluorescent dye approved by the FDA, is widely utilized in biomedical applications due to its excellent biocompatibility, photophysical properties, and versatility in imaging and...The content of this RSS Feed (c) The […]Jinghang Li
- Metabolic click-labeling of interleukin-10 enhances the immunomodulatory potential and wound healing properties of mesenchymal stem cell-derived extracellular nanovesicles Tháng 6 25, 2025Biomater. Sci., 2025, Advance ArticleDOI: 10.1039/D4BM01601G, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Hee Gyeong Ko, Yun-A Kim, Jun Kwon, So Won Jeon, Jong Sang Yoon, Min-Ho Kang, Ju-Ro Lee, Han Young KimIntegration of interleukin-10 to mesenchymal stem cell-derived extracellular nanovesicles effectively enhances anti-inflammatory responses in both […]Hee Gyeong Ko
- Engineered PD-L1 Nanoregulators for Enhanced Tumor Immunotherapy Tháng 7 11, 2025