RSC – Biomater. Sci. latest articles- Multifunctional Janus hemostatic dressings tailored for complex coagulation processes May 18, 2026Biomater. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6BM00392C, Review ArticleLiyan Ding, Yicheng Zhang, Weijie Guo, Yunxiang Weng, Yan Fang, Haiqing Liu, Qinhui ChenThe development of highly efficient hemostatic materials is of great significance for trauma treatment. Hemostasis occurs through the synchronous interaction of the following three mechanisms containing vasoconstriction, platelet aggregation and...The content of this RSS Feed […]Liyan Ding
- A glucose-responsive dual-nanoparticle–hydrogel-based microneedle patch for co-delivery of insulin and exendin-4 May 17, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D6BM00181E, PaperTingting Zhang, Sainan Liu, Qiyao Ma, Suning He, Fan Huang, Linqi Shi, Rujiang MaA dual-nanoparticle–hydrogel-based microneedle (MN) patch for the co-delivery of insulin and exendin-4.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society […]Tingting Zhang
- Integrated cascade catalysis of AuPtCu nanozymes and glycolysis inhibition for synergistic breast cancer therapy via metabolism regulation May 17, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D6BM00208K, PaperKanglong Wang, Cheng Ni, Junhao Huang, Yunfei Huang, Xueyan Cao, Jing Ma, Xiangyang Shi, Rui GuoBy integrating the multi-enzyme cascades of AuPtCu nanozymes with 2-DG-mediated glycolytic inhibition, this nanoplatform inhibits tumor growth and suppresses metastasis via a synergistic effect of metabolic regulation and amplified oxidative stress.To cite this article before page numbers are assigned, […]Kanglong Wang
- Biomimetic Injectable Methacrylated Chondroitin Sulfate-Collagen Hydrogels Enhance Chondrocyte Function and Promote Osteochondral Regeneration May 16, 2026Biomater. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6BM00316H, PaperYining Yang, Yanni Li, Yu Zhang, Lujing Zhang, Kaisheng Wang, Xiaoyue Xu, Mengyao Li, YAN YANG, Yuankai ZhangThe development of biomimetic scaffolds capable of promoting both cartilage and subchondral bone regeneration remains a major challenge in osteochondral tissue engineering. In this study, type I acidsoluble collagen (ASC)...The content of […]Yining Yang
- Light-programmable, high drug-loading nanomedicine based on dimeric camptothecin May 14, 2026Biomater. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6BM00328A, PaperLei Wu, Yehan Wang, Kaimin Cai, Yang Zhou, Yong Wang, Jianjun Cheng, Hua He, Lichen YinEfficient nano-encapsulation of highly hydrophobic chemodrugs and spatiotemporal control over drug release remain critical challenges for nanomedicine. Herein, we design light-programmable, high drug-loading PEG-PLA nanoparticles (hQCC NPs) to co-encapsulate both...The content of this RSS […]Lei Wu
- Dual-targeting macrophage membrane nanosystem enhances radiotherapy-induced antitumor immunity via synergistic nuclear and mitochondrial DNA damage May 13, 2026Biomater. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6BM00279J, PaperGuangyu Ju, Qi Ding, Hongcang Gu, Rao Liu, Xiao Liu, Zimeng Wang, Kaiwei Wang, Yuan Ping, Jian You, Shuanghu Yuan, junchao QianRadiotherapy (RT) can trigger immune-related signaling in addition to its direct cytotoxic effects. However, in many cases, this immune activation is not strong enough to produce durable antitumor […]Guangyu Ju
- The LDHs biological hybrid promotes electron transfer via dual starvation enhancing tumor Ferroptosis/Apoptosis May 12, 2026Biomater. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6BM00304D, PaperWenwen Zhu, Senbin Chen, Jintao Zhu, Bengao ZhuCurrent strategies for metabolic regulation within the tumor microenvironment (TME) often rely on exogenous drugs, leading to transient benefits and necessitating repeated administrations that frequently cause detrimental side effects. To...The content of this RSS Feed (c) The Royal Society of ChemistryWenwen Zhu
- Inhalable viromimetic polymer nanoparticle vaccine (iVPNVax) in a subcutaneous-prime/inhalation-boost vaccination schedule for eliciting durable mucosal and systemic immune protection May 11, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D6BM00350H, PaperZhenyi Zhu, Xinyu Zhuang, Zichao Huang, Chenchao Zhang, Tong Zhang, Liping Liu, Aolin Sun, Jiangai Long, Yusong Cao, Yaxin Zhang, Ying Xing, Songhui Yang, Jianan Peng, Siyou Huang, Ningning Hu, Mingyao Tian, Wantong Song, Xuesi ChenAn inhalable viromimetic nanoparticle vaccine resolves the size mismatch between aerosol deposition and immune […]Zhenyi Zhu
- The effect of the physicochemical properties of hydrogels on chronic inflammation by macrophage polarization May 11, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D6BM00025H, Review ArticleQinghong Wu, Kai Jia, Yang Liu, Yunbao Zhang, Nan Jiang, Lala Li, Yu Liu, Li LiBy precisely controlling the mechanical and physicochemical properties of hydrogels, it is possible to directionally remodel the immune microenvironment, providing a key strategy for the treatment of chronic inflammation.To cite this article before […]Qinghong Wu
- Hydrogel-Exosome Synergistic System: Mechanisms, Applications and Future Prospects in Regenerative Medicine May 10, 2026Biomater. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6BM00274A, Review ArticleBin Xie, Yuyi Kang, Shuihao Zhao, Zhiyun Wu, Zelin Wu, Xiubin Kuang, Jiahong Jiang, Nuo Xu, Xudong Lin, Jun Wu, Tak Man Wong, Shaoquan Bian, Xiaoli Zhao, Zhengqiang YuanHydrogels and exosomes are mutually beneficial and thus can be combined for regenerative medicine and innovative therapies. This strategy takes […]Bin Xie
- A Janus-structured PVA/collagen membrane co-loaded with Orthosiphon aristatus extract and DMOG for diabetic wound healing May 8, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D6BM00266H, PaperFan-Ting Meng, Xue Xu, Lin Zhu, Yi Xie, Hai-Yan Wang, Yu-Qing ZhangA Janus-structured PVA/collagen membrane co-loaded with Orthosiphon aristatus extract and DMOG accelerates diabetic wound healing through antioxidant, antimicrobial, and pro-angiogenic effects.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of […]Fan-Ting Meng
- Biomimetic characterization by micro-computed tomography (μCT) of 3D hollow fibre membrane network bioreactors for tissue engineering May 7, 2026Biomater. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6BM00185H, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Giuseppe Falvo D'Urso Labate, Chiara Morano, Thomas De Schryver, Harry Zaverdas, Luigi De Napoli, Gionata Fragomeni, Luc Van Hoorebeke, Patrick Segers, Mathieu Boone, Konstantinos Theofilatos, Joerg Christian Gerlach, Gerardo CatapanoHollow Fiber Membrane Bioreactors (HFMBs) […]Giuseppe Falvo D'Urso Labate
- Mechanobiological Regulation of Endothelial Vascularization after Myocardial Infarction: Matrix Mechanics, Hydrogels Strategies and Applications May 7, 2026Biomater. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5BM01885D, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Yanzhe Qian, Yuan YaoMyocardial infarction (MI) triggers a wound-healing cascade that restores structural integrity but reshapes the cardiac mechanical microenvironment. The transition from compliant, healthy myocardium to stiff, fibrotic scar tissue creates biomechanical...The […]Yanzhe Qian
- Bioinspired synergistic chitosan–graphene–tannin hydrogel orchestrates inflammation resolution and accelerates skin tissue repair May 5, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D5BM01612F, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Isleidy Ruíz, Luisbel González, Julia Eduarda Schneider Gregória, Cintia Sena Bueno, Maria Esméria Corezola do Amaral, Guilherme Ferreira Caetano, Katherina FernándezWound healing remains a major clinical challenge due to the complex metabolic disturbances present […]Isleidy Ruíz
- Genetically engineered Spirulina plantensis producing human insulin as a potential novel oral drug delivery carrier May 4, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D5BM00817D, PaperDhaval Patel, Eliyahu Drori, Valeria Rahamim, Aman Thakur, Adi Dahan, Sivan Meir, Yamm Anker, Palak Sangrai, Yaakov Anker, Aharon AzaguryEngineered Spirulina as a living, edible bioreactor and carrier: stable expression of bioactive human insulin, scalable production, and enhanced intestinal uptake—advancing a bioadhesive, noninvasive paradigm for oral protein delivery.To cite this article […]Dhaval Patel
- Coordination-driven liquid-to-solid phase transition and self-assembly of DNA–metal condensates May 4, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D6BM00380J, PaperSongtao Zhou, Li Zhang, Yuxuan Lin, Min Bao, Yongxiu Song, Yunlu Dai, Yufeng Pei, Jie SongThis study reveals a new mechanism of DNA–ferrous ion assembly: by coupling phase separation with self-assembly processes and precisely controlling the reaction conditions, we achieved the formation of nanospheres, nanofibers, and nanoribbons.To cite this […]Songtao Zhou
- Correction: An ROS-sensitive tegafur-PpIX-heterodimer-loaded in situ injectable thermosensitive hydrogel for photodynamic therapy combined with chemotherapy to enhance the tegafur-based treatment of breast cancer May 4, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D5BM90099A, Correction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Zhiqiang Zhang, Anning Li, Xingqi Min, Qunqun Zhang, Jun Yang, Guo Chen, Meijuan Zou, Wei Sun, Gang ChengTo cite this article before page numbers are assigned, use the DOI form of citation above.The content […]Zhiqiang Zhang
- Silica-coated papillomavirus-based nanoparticles: a shielded scaffold for HIV-1 vaccines May 3, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D5BM01792K, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Yu Wang, Kathrin Kostka-Wirtz, Nils Bartelsen, Kateryna Loza, Christoph Weingärtner, Philipp Arnold, Dominik Damm, Klaus Überla, Matthias Epple, Vladimir TemchuraSilica-coated HPV L1 VLPs shield scaffold-directed immunity while enabling multivalent display of HIV-1 Env trimers […]Yu Wang
- Beyond first responders: neutrophils shape biomaterial-guided regeneration May 1, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D6BM00277C, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Márcia Monteiro Pereira, Ana Beatriz Sousa, Judite Novais BarbosaNeutrophils actively shape biomaterial-guided regeneration by orchestrating angiogenesis, inflammation resolution, and tissue repair through their remarkable functional plasticity.To cite this article before page numbers are […]Márcia Monteiro Pereira
- Inflammation-responsive hierarchical delivery of anti-inflammatory siRNA and peptide alleviates cytokine storm in pneumonia April 29, 2026Biomater. Sci., 2026, Advance ArticleDOI: 10.1039/D5BM01911G, PaperXiaohui Li, Shanzhou Duan, Jiandong Yang, Chunxian Piao, Yang Zhou, Chenglong Ge, Qiujun Liang, Minhyung Lee, Lichen Yin, Yongbing ChenInflammation-responsive nanocomplexes (NCs) capable of penetrating both the mucus and cytomembrane barriers were developed for acute lung injury treatment through siRNA-mediated TNF-α silencing and RBP-mediated RAGE blocking.To cite this article […]Xiaohui Li
- Multifunctional Janus hemostatic dressings tailored for complex coagulation processes May 18, 2026