Analyst

RSC – Analyst latest articles

• Characterizing DPPM Inhibition of Butyrylcholinesterase: Integrated Enzymatic Kinetics and Raman Spectroscopy with Chemometric Analysis November 21, 2025
  Analyst, 2025, Accepted ManuscriptDOI: 10.1039/D5AN01018G, PaperAubrey Barney, Ashley Newland, Abraham Olayeri, Jan Halamek, Lenka HalamkovaButyrylcholinesterase (BChE) may serve as a scavenger enzyme protecting against various toxic compounds, but we still don't fully understand how it interacts with fentanyl analogues. We investigated how Despropionyl meta-methyl...The content of this RSS Feed (c) The Royal Society of Chemistry
  Aubrey Barney
• Computational and Design of Experiment Strategies to Improve Differentiation and Quantitation of Trace-Level Cannabinoids by Copper Cationization Paper Spray Mass Spectrometry November 19, 2025
  Analyst, 2025, Accepted ManuscriptDOI: 10.1039/D5AN01073J, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jindar Nikolaus Silvio N.S. Sboto, Chris GillThe medicinal and recreational use of cannabis products is quickly rising from increased worldwide legalization and decriminalization. Despite this, current analytical methods have compromises when analyzing common isobaric cannabinoids, […]
  Jindar Nikolaus Silvio N.S. Sboto
• Dramatically Enhancing Electrochemiluminescence Performance in Aqueous Phase Using Naphthalene Diimides with Excellent Electron-Transfer Capability and Water Solubility November 18, 2025
  Analyst, 2025, Accepted ManuscriptDOI: 10.1039/D5AN01074H, PaperZhengang Han, Dalong Xu, Yuqi Wang, Mingxiu Tian, Liuxiang ChenLuminescent substances with superior electron transfer capability and excellent water solubility are ideal candidates for constructing high-performance electrochemiluminescence (ECL) sensors. In this work, we designed and synthesized a series of...The content of this RSS Feed (c) The Royal Society of Chemistry
  Zhengang Han
• Microanalysis of a single droplet produced by optical tweezers in an aqueous solution of bovine serum albumin November 18, 2025
  Analyst, 2025, Accepted ManuscriptDOI: 10.1039/D5AN01045D, PaperAyana Takayanagi, Yasuyuki Tsuboi, Ken-ichi YuyamaThe liquid–liquid phase separation of proteins is associated with the generation of membraneless organelles as well as of crystals and amyloid fibrils. The phase separation proceeds through spontaneous concentration fluctuations,...The content of this RSS Feed (c) The Royal Society of Chemistry
  Ayana Takayanagi
• Boosting Living Bacillus Spore Identification: Kolmogorov-Arnold Network-Guided Convolutional Neural Network Combined with Laser Tweezers Raman Spectroscopy November 14, 2025
  Analyst, 2025, Accepted ManuscriptDOI: 10.1039/D5AN00834D, PaperYifan Sun, Peng Xiao, Fusheng Du, Lin He, Yuan Lu, Yufeng Yuan, Junle QuAs primary carriers of foodborne and zoonotic diseases, Bacillus spores can pose serious threat for food microbiology and human disease. Thus, precise identification of Bacillus spores is of great significance...The content of this RSS Feed (c) The […]
  Yifan Sun
• Determination of veliparib metabolic stability in the human liver microsomes using a hydrophilic interaction UPLC-MS/MS quantitative method: greenness assessment with an in silico study for ADME, DEREK alarms and metabolic lability November 13, 2025
  Analyst, 2025, Advance ArticleDOI: 10.1039/D5AN01132A, PaperMohamed W. Attwa, Ali S. Abdelhameed, Haitham AlRabiah, Adnan A. KadiVeliparib exhibited a relatively slow extraction ratio, with a low Clint of 22.23 mL min−1 kg−1 and a long t1/2 of 36.48 min. Minor replacements within the pyrrolidine ring (96%) in veliparib may increase the metabolic stability and safety profile.To […]
  Mohamed W. Attwa
• Transition metal doping boosting paper-based photoelectrochemical immunosensing for neurofilament light chain protein detection November 13, 2025
  Analyst, 2025, Accepted ManuscriptDOI: 10.1039/D5AN01030F, PaperCheng-Hua Xu, An-Yang Tao, Mei-Qing Meng, Xi-Le Zhang, Cheng Fang, Feng-Zao Chen, De-Man HanEarly diagnosis of neurodegenerative diseases relies on highly sensitive detection of their specific biomarkers. However, existing photoelectrochemical (PEC) sensing technologies, despite the promising prospects, exhibit significant limitations in detection stability,...The content of this RSS Feed (c) The […]
  Cheng-Hua Xu
• Metabolic Fingerprinting of Periodontal Bacteria: A Multi-scale Mass Spectrometry and Vibrational Spectroscopy Approach November 12, 2025
  Analyst, 2025, Accepted ManuscriptDOI: 10.1039/D5AN00507H, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Jawaher Albahri, Daniel Smaje, Yun Xu, Steven Robinson, Heather Allison, Kathryn A. Whitehead, Howbeer MuhamadaliPeriodontitis is a prevalent condition characterised by progressive destruction of the supporting periodontium around teeth, resulting from prolonged interaction between the […]
  Jawaher Albahri
• DNAzyme amplifier-based immunoassay for small molecule detection November 11, 2025
  Analyst, 2025, Accepted ManuscriptDOI: 10.1039/D5AN01013F, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Han Pang, Qiang ZhaoDetection of small molecules is urgent for many applications, such as drug discovery, disease diagnosis, food safety, and environmental monitoring. Developing simple, selective, and sensitive methods to detect small molecules...The content of […]
  Han Pang
• SpectralFlow: An integrated platform for spectral data preprocessing and predictive modeling analysis in fruit quality evaluation November 10, 2025
  Analyst, 2025, Accepted ManuscriptDOI: 10.1039/D5AN00794A, PaperZhikai Chen, Guanzhi Lyu, Xiaochan Wang, Mengfei Yang, Xin Xu, Xiaolei ZhangThe near infrared spectroscopy and hyperspectral imaging offer unique analytical advantages and immense application potential in fruit quality evaluation. However, most existing spectral analysis software is limited to simple machine...The content of this RSS Feed (c) The Royal Society […]
  Zhikai Chen