RSC – Analyst latest articles- Cellular-level lipidomics of two-dimensional cultures of adherent gut epithelial cell lines reveals a metabolic switch April 26, 2026Analyst, 2026, Accepted ManuscriptDOI: 10.1039/D5AN01183C, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Qianying Xu, Jake Penny, Emily Fraser, Federica Orsenigo, Matteo Barberis, Lee A Gethings, Melanie J. Bailey, Clare MillsIn vitro cell models of the gut epithelium, particularly those based on the Caco-2 and HT29-MTX cell lines, […]Qianying Xu
- A Two-Point Fluorescence Detection Flow Cell with Empirical Calibration for High Optical Density Analysis April 26, 2026Analyst, 2026, Accepted ManuscriptDOI: 10.1039/D6AN00106H, Communication Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Davor Šakić, Tin WeitnerA two-point fluorescence detection flow cell with empirical calibration is presented for correcting inner-filter effects at high optical densities. Using only fluorescence signals from fixed detection points, linear fluorescence–concentration relationships...The content of […]Davor Šakić
- Multi-Modal Structure Characterization of Synthetic Batch Impurities with Liquid Chromatography Coupled to Infrared Ion Spectroscopy April 26, 2026Analyst, 2026, Accepted ManuscriptDOI: 10.1039/D5AN01339A, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Teun van Wieringen, Simon Perry, Agisilaos Chantzis, Giel Berden, Jos Oomens, Mansoor Saeed, Jonathan MartensAssessing the safety of agrochemical products requires a thorough structural identification of synthetic batch impurities. The traditional method, relying on liquid […]Teun van Wieringen
- Advances and Opportunities in Point-of-Care Detection of Toxic Metals: A Review of Electrochemical and Non-Electrochemical Approaches April 26, 2026Analyst, 2026, Accepted ManuscriptDOI: 10.1039/D6AN00248J, Critical ReviewNavoda Udawaththa, Olga Zubak, Ashley Daninger, Ralph Page, Miriam Strini, Brianna Romero, Pavithra PathirathnaHeavy metal contamination remains a persistent global threat to human health and the environment, driving the urgent need for rapid, portable, and sensitive detection technologies. Recent advances in point-of-care (POC)...The content of this RSS Feed (c) […]Navoda Udawaththa
- Hydropyrolysis: towards fluorescence-free Raman spectroscopy analysis of internal diesel injector deposits April 22, 2026Analyst, 2026, Advance ArticleDOI: 10.1039/D5AN00347D, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Joel Viggars, Sarah Angel-Smith, Graham A. Rance, Ahmed Khairy, Will Meredith, Adrienne Davis, Jim Barker, Jacqueline Reid, David J. Scurr, Colin E. SnapeThe application of hydropyrolysis (HyPy) to a series of Internal Diesel Injector Deposits […]Joel Viggars
- Fluorescent nanodiamonds: preparation and quantum sensing for biological analysis April 22, 2026Analyst, 2026, Advance ArticleDOI: 10.1039/D6AN00103C, MinireviewShingo Sotoma, Kota Shiraya, Daisuke Fujimaki, Kai OtsuFluorescent nanodiamonds containing nitrogen-vacancy centers are next-generation bioprobes. This Minireview outlines their preparation and surveys their applications to intracellular temperature, radical, and rotational sensing.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS […]Shingo Sotoma
- Upcycling Lemon Peel Waste into Sustainable Bioactive Ingredients.Chemical Characterization and Efficacy Assessment April 21, 2026Analyst, 2026, Accepted ManuscriptDOI: 10.1039/D6AN00048G, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Ritamaria Di Lorenzo, Ilaria Neri, Raffaele Raimondo, Daniela D Matteo, Carlo Irace, Maria Grazia Ferraro, Mariavittoria Verrillo, Teresa Ponticorvo, Teresa Di Serio, Sonia Laneri, Lucia GrumettoThe upcycling of agro-industrial by-products emerged as a sustainable strategy […]Ritamaria Di Lorenzo
- Simultaneous Quantitation of Structurally Analogous Bile Acid Isomers via Charge-State-Engineered UPLC-MS April 21, 2026Analyst, 2026, Accepted ManuscriptDOI: 10.1039/D6AN00420B, PaperDesen Su, Yunyun Zheng, Xiuxian Lin, Ziqiang Chen, Minmin Huang, Qinghua Yao, Yuwu ChiUrsodeoxycholic, hyodeoxycholic, chenodeoxycholic, and deoxycholic acid are endogenous, dihydroxylated bile acid isomers that share a molecular mass but fulfill specific biological roles. However, their isomeric structures complicate analytical separation, while...The content of this RSS Feed (c) The […]Desen Su
- Toward real-time protein profiling in biofluids using discriminative Raman spectral markers April 20, 2026Analyst, 2026, Advance ArticleDOI: 10.1039/D5AN00887E, PaperKadambari Jandhyala, Priyanka DeySimultaneous analysis of multiple proteins in liquid biopsies is essential for accurate disease diagnosis and monitoring yet remains challenging in complex biological matrices when proteins exhibit high structural similarity.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this […]Kadambari Jandhyala
- Zinc Finger Protein Arrays in an Epoxy-Functionalized, Pump-Free Microfluidic Device for Amplification-Free, Colorimetric Detection of Double-Stranded DNA April 20, 2026Analyst, 2026, Accepted ManuscriptDOI: 10.1039/D6AN00224B, PaperShaikh Bhuiyan, Rylan Isaiah Shumway, Christine A Trinkle, Moon-Soo KimRapid pathogen detection is essential during the early stages of disease treatment, as timely identification directly influences the selection of appropriate therapeutic agents. Zinc finger domains can be engineered into...The content of this RSS Feed (c) The Royal Society of ChemistryShaikh Bhuiyan
- Cellular-level lipidomics of two-dimensional cultures of adherent gut epithelial cell lines reveals a metabolic switch April 26, 2026