RSC – Anal. Methods latest articles- Real-time smartphone-based multi-parameter detection of nitrite, ammonia nitrogen, and total phosphorus in water June 26, 2025Anal. Methods, 2025, Advance ArticleDOI: 10.1039/D5AY00251F, PaperHao-Yu Zhang, Yan Zhang, Dengni Lai, Li-Qun Chen, Le-Qian Zhou, Chang-le Tao, Zhou Fang, Rui-Rui Zhu, Wen-Qi Long, Jun-Wu Liu, Ying-Chun Fang, Jia Zhao, Zhi-Bin Wu, Lin Luo, Yuan YangA smartphone-based, 3D-printed portable six-channel device, utilizing an adaptive deconvolution algorithm, enables real-time, on-site, synchronous, and high-precision water quality detection […]Hao-Yu Zhang
- Targeting liposome and accelerated CRISPR system for selective imaging miR-21 in cell June 25, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D5AY00619H, CommunicationWenyue Zhang, Mengting Wu, Qingqing Zhang, Xibin Chen, Yingshu GuoThis study demonstrated a liposome-targeted and accelerated CRISPR strategy for specific response of miR-21 within MCF-7 cells. Targeting was achieved with the help of modification of the MUC1 aptamer. MnO2...The content of this RSS Feed (c) The Royal Society of […]Wenyue Zhang
- Polypyrrole-coated GCE Sensor for sensitive detection of 5-Fluorouracil via molecular imprinting June 25, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D5AY00345H, PaperManjeet Harijan, Akriti Srivastava, Meenakshi SinghCytotoxic drug 5-fluorouracil (5-FU) is a fluorine derivative of uracil; it is one of the most significant medications used to treat cancers of the stomach, breast, colon, pancreas, and cervical...The content of this RSS Feed (c) The Royal Society of ChemistryManjeet Harijan
- A hybridization chain reaction-based electrochemical sensor for rapid detection of respiratory pathogens June 24, 2025Anal. Methods, 2025, Advance ArticleDOI: 10.1039/D5AY00418G, PaperYuting Shan, Dongmei Zhang, Yao Liu, Yijie Wang, Jiufa Zhang, Cuiping Ma, Yang Li, Chao ShiAn electrochemical scheme for efficient and sensitive detection of respiratory viruses.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal […]Yuting Shan
- A lysosome targetable and acidic pH-activated fluorescent probe for two-photon imaging of hydrogen sulfide in live cells and animals June 24, 2025Anal. Methods, 2025, Advance ArticleDOI: 10.1039/D5AY00757G, PaperYuJia Fu, XiaoFeng Guo, Hong WangThe illustration of a lysosome-targeted probe and its in situ response to H2S controlled by the acidic environment in lysosomes.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society […]YuJia Fu
- Chemiluminescence video assisted by chemometrics modeling for forensic identification of blood in crime scene June 23, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D5AY00633C, PaperThomas Tributino, José R. Sabino-Junior, Licarion Pinto, Tadeu Morais Cruz, Jose Ailton M. Nascimento, Severino Carlos B. Oliveira, Vagner Bezerra dos SantosThe development of advanced chemiluminescent compounds and hematology methodologies has significant implications for forensic science particularly in the detection of evidential residues at crime scenes. This study introduces […]Thomas Tributino
- Selective Detection of Tyrosine Kinase Inhibitor Erdafitinib Using Nitrogen-Doped Carbon Dots Synthesized at Room Temperature June 22, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D5AY00833F, PaperMohamed N. Goda, Laila S. Alqarni, Hossieny Ibrahim, Mohamed El-Wekil, Almontaser AliErdafitinib (ERDF), despite its known adverse effects, remains a key chemotherapeutic agent for metastatic urothelial carcinoma, requiring reliable monitoring in biological matrices to ensure safe and effective treatment. In this...The content of this RSS Feed (c) The Royal […]Mohamed N. Goda
- Design novel optical sensor for determination of cadmium based on immobilization of β-2-hydroxybenzyl-5-chloro-2-hydroxyazastyrene on agarose membrane June 22, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D5AY00817D, PaperMuneera Alrasheedi, Ahmed Alanazi, Amnah Salem Al Zbedy, Alaa M. Younis, Alaa S. AminAn optode featuring high selectivity was prepared for cadmium detection via chemically binding β-2-hydroxybenzyl-5-chloro-2-hydroxyazastyrene (HCHAS) onto a clear agarose membrane. Colorimetric analysis of complexation between HCHAS and various metal ions...The content of this RSS Feed (c) […]Muneera Alrasheedi
- Ultrasensitive detection of deoxynivalenol by mass spectrometric immunoassay with cascade signal amplification June 22, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D5AY00724K, CommunicationHanxu Ji, Jingjing Xu, Yufeng Li, Xiaoxiao Wu, Diyao Jiang, Xiuming Mei, Miao Yang, Yuwei Qiang, Jungui Zhou, Chi ZhangWe developed a novel mass spectrometry immunoassay for the ultrasensitive and selective detection of deoxynivalenol by introducing nucleic-acid-amplification techniques. By selecting thymine as mass tag, the primer DNA modified on...The […]Hanxu Ji
- Mediating in situ-generated fluorescence for Au nanocluster-based multi-color ratio detection of alkaline phosphatase June 22, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D5AY00835B, PaperChao-Zhe Zhu, Shuo Tian, Hua-Nong Ting, Mengke Wang, Yufeng WangThe portable, rapid, and accurate detection methods for alkaline phosphatase (ALP) can significantly improve the efficiency and accuracy of medical testing, especially in early disease screening. Herein, a fluorescent detection...The content of this RSS Feed (c) The Royal Society of […]Chao-Zhe Zhu
- Application of 2D-Liquid Chromatography for the Separation of a Mixture of Isomeric and Structurally Related Azatryptophan Derivatives June 19, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D5AY00473J, PaperParinita Shaw, Pandidurai Sekar, Balasaheb Chavan, Sharad Duche, Arvind Mathur, Amrita Roy RoyThe present study describes the critical achiral and chiral separation of a mixture of azatryptophan derivatives having positional isomers or isobars and their enantiomers, which is successfully achieved using 2D...The content of this RSS Feed (c) The […]Parinita Shaw
- Dual-mode detection strategy for alkaline phosphatase activity based on dimeric G-quadruplex June 19, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D5AY00934K, PaperYangfan Chen, Xi Zhou, Hai-Lun He, Changbei Ma, Dejian YuanAlkaline phosphatase (ALP) is an important hydrolase found in mammalian tissues, which plays a crucial role in numerous fundamental physiological processes within organisms by means of dephosphorylation. From a clinical...The content of this RSS Feed (c) The Royal Society of […]Yangfan Chen
- Freeze-drying enhances ToF-SIMS imaging of biological tissues via structural and metabolic preservation June 19, 2025Anal. Methods, 2025, Advance ArticleDOI: 10.1039/D5AY00550G, PaperHongzhe Ma, Mingru Liu, Yuxuan Zhang, Mengjiao Sun, Yanhua Chen, Zhaoying Wang, Zeper AblizIn the ToF-SIMS in situ analysis of mouse liver tissue, freeze-drying is superior to room-temperature drying and chemical fixation, minimizing lipid spillage while maintaining structural integrity.To cite this article before page numbers are assigned, use the […]Hongzhe Ma
- Recent advances of organelle-targeted fluorescent probes for hydrogen peroxide June 19, 2025Anal. Methods, 2025, Advance ArticleDOI: 10.1039/D5AY00597C, MinireviewLinke Li, Ying-ying Chen, Yu-jie ZhangFluorescent probes targeting organelle H2O2.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of ChemistryLinke Li
- A novel IagPLS baseline correction method for glioma identification using Raman spectroscopy June 19, 2025Anal. Methods, 2025, Advance ArticleDOI: 10.1039/D5AY00792E, PaperYiran Shao, Lipu Zhou, Yan Zhou, Yibo Li, Qingbo LiWe propose IagPLS, a novel Raman baseline correction method integrating curvature-driven regularization, SHAP-guided feature protection, and quantum-inspired optimization, significantly enhancing spectral fidelity for glioma detection.To cite this article before page numbers are assigned, use the DOI form of citation above.The […]Yiran Shao
- β-propiolactone, Its Application and Assay Methods June 19, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D5AY00024F, Tutorial ReviewSeyedeh Zohreh Mirjalili, Reyhaneh Sabourian, Fatemeh Chavoshi, Mehrnoosh Shirangi, Zahra Tamiji, Farzad Kobarfard, Mohsen AminiVaccination is a crucial tool in the prevention of infectious diseases and has saved countless lives worldwide. One of the most commonly used techniques for producing vaccines is viral deactivation....The content of this RSS […]Seyedeh Zohreh Mirjalili
- Introduction to neutron techniques for cultural heritage June 18, 2025Anal. Methods, 2025, Advance ArticleDOI: 10.1039/D5AY90075A, AMC Technical Brief Analytical Methods Committee, AMCTB No. 118Neutrons are an ideal probe for the non-invasive scientific investigation of cultural heritage materials, producing images and plots that reflect the macro/micro-structure and composition of objects, especially those made of metal, ceramic or stone.To cite this article before page numbers are […]Analytical Methods Committee, AMCTB No. 118
- Quantification of protein in complex sample by gel electrophoresis with online intrinsic fluorescence imaging and Gaussian fitting arithmetic June 18, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D4AY02064B, PaperXinke Zhai, Yiren Cao, Youli Tian, Ke-er Chen, Zixian Yu, Qiang Zhang, Chengxi Cao, Xu XuTraditional polyacrylamide gel electrophoresis (PAGE) has been widely used for analysis of proteins. However, the protein quantification (PQ) based on SDS-PAGE with staining remains inaccurate, time-consuming and complex. Even the...The content of this RSS […]Xinke Zhai
- First-in-class hydrazone-pyrazoline sensors for selective detection of Zn2+, Cd2+, and Hg2+ in aqueous environments June 17, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D5AY00639B, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Alexander CiupaSix first-in-class pyrazoline-hydrazone fluorescent sensors that distinguish Zn2+, Cd2+ and Hg2+ at three separate wavelengths in aqueous environments are reported. Lead sensor P1 was validated for the detection of the...The content of this […]Alexander Ciupa
- Innovative multispectral sensor for rapid wine adulteration detection using wavelength selection algorithms June 17, 2025Anal. Methods, 2025, Accepted ManuscriptDOI: 10.1039/D5AY00751H, PaperChengbo Yang, Jingjun Wu, Zhouqing Qian, Zhiliang ZhaoEffective detection of wine adulteration can protect the rights and interests of consumers and producers. The combination of spectroscopic technology and chemometric methods can achieve adulteration discrimination of wine, providing...The content of this RSS Feed (c) The Royal Society of ChemistryChengbo Yang
- Real-time smartphone-based multi-parameter detection of nitrite, ammonia nitrogen, and total phosphorus in water June 26, 2025
