RSC – Anal. Methods latest articles- A novel molecular imprinted quartz crystal microbalance sensor for fenamiphos determination based on boron-sulphur co-doping ultra-thin graphitic carbon nitride incorporated Cu-MOF January 20, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY02149A, PaperŞule Yıldırım Akıcı, Ahmet Düzel, Ülkü Melike Alptekin, Sena Bekerecioğlu, İlknur Polat, Necip Atar, Mehmet Lütfi YolaFenamiphos (FEN) as organophosphorus insecticide is frequently used in recent years to control many nematode pests. Nonetheless, its important adverse effects have currently attracted attention in humans and the ecological...The content of this […]Şule Yıldırım Akıcı
- CRISPR/Cas12a platform activated by protospacer adjacent motifengineered DNA circuit for specific target sensing January 20, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY02079D, PaperRui Wang, Wei Li, Jiayue Li, Yuchen Zheng, Ning WeiCRISPR/Cas systems have found extensive applications in nucleic acid diagnostics. However, the generalizability of this approach, particularly for the sensing of non-nucleic acid targets, remains a challenge. This study presents...The content of this RSS Feed (c) The Royal Society of […]Rui Wang
- A Novel Cloud Point Extraction Method Using a Benzimidazole-Based Ligand for the Preconcentration of Toxic Heavy Metals in Water and Food Samples January 20, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D6AY00036C, PaperOlcay Ozdemir, Celal Duran, Emre Menteşe, Duygu OzdesIn the present research, a novel cloud point extraction (CPE) method was developed for the separation and preconcentration of toxic Cu(II), Ni(II), Pb(II), and Cd(II) ions in environmental water and...The content of this RSS Feed (c) The Royal Society of ChemistryOlcay Ozdemir
- Multi-Detector Frit-Inlet Asymmetric Flow Field-Flow Fractionation Method Development For Nanoparticle Mixtures: Deeper Analysis Beyond ISO Quality Standards January 20, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01758K, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Rand Abdulrahman, Panida Punnabhum, Lisa Van Den Driest, Nicholas John William Rattray, Robin Capomaccio, Kevin Treacher, Yvonne Perrie, Zahra RattrayLipid-based nanoparticles (LNPs) are transforming the field of drug delivery, with one gene therapy product […]Rand Abdulrahman
- A Visual Protocol for Sensitive Vibrio parahaemolyticus Detection Based on Hybridization chain reaction cascaded DNAzyme January 20, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY02046H, PaperJiali Wang, Qian Cui, Shu Zeng, Danfeng Fu, Daoyun Peng, Fei Chen, Yi Wan, Anwei WangVibrio parahaemolyticus (V. parahaemolyticus) is one of the most harmful pathogenic bacteria derived from seafood and could cause great damage to aquaculture and human health even at low concentrations. Rapid...The content of this RSS […]Jiali Wang
- Sensitive Electrochemical Platform for Paracetamol Monitoring in Real Matrix via Supramolecular Calix[6]arene-CuO hybrid Nanocomposite January 19, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01939G, PaperHyder Ali, Muhammad Balal Arain, Jameel Ahmed Baig, Ayaz Ali Memon, Mustafa SoylakParacetamol is widely used analgesic and antipyretic which commonly employed to alleviate symptoms of cold and flu. It is effective in reducing pain and fever and is readily available as...The content of this RSS Feed (c) The […]Hyder Ali
- A MOF with high specific surface area for rapid separation and determination of β-adrenergic receptor blockers in pork by open-tubular capillary electrochromatography January 19, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01941A, Paperlidi Gao, Jiawen Yu, Dongsheng Zhao, Xinyu Liang, Jun Wang, Fuquan Zhao, Ming Zhao, Hongtao Chu, Shili QinIn this work, a novel Ti-based MOF (NH2-MIL-125) bonded open-tubular (OT) column was firstly prepared via one-step in-situ growth method for capillary electrochromatography (CEC). The stationary phase was characterized by...The content of […]lidi Gao
- Aptamer-Functionalized 3D Gold Nanodendrite Platform for Electrochemical Detection of Circulating Tumor Cells in Breast Cancer January 19, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01680K, PaperRuochen Wu, Li Lu, He Jiang, Dali Hu, Hepeng SuCirculating tumor cells (CTCs) are critical biomarkers of breast cancer metastasis, yet their low abundance and phenotypic heterogeneity present formidable challenges for reliable detection. Here, we report the design and...The content of this RSS Feed (c) The Royal Society of […]Ruochen Wu
- Fingerprinting combined with chemometrics: new strategies and advances in quality evaluation of traditional Chinese medicine January 19, 2026Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY01692D, MinireviewYibing Yao, Mingze Li, Lijun Zhang, Jingran Meng, Long Liu, Wei Li, Jing ZhangFingerprinting combined with chemometrics: new strategies and advances in quality evaluation of traditional Chinese medicine.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) […]Yibing Yao
- Monitoring production processes of pharmaceutical and farm chemical with near-infrared spectra coupled with interaction moving window partial least squares January 15, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01996F, PaperShuming Lan, Yiping Du, Min Ding, Yan Zhang, Honghong WangOn-line near infrared spectroscopy is utilized to monitor production processes of pharmaceutical and farm chemical. To improve the model performance, interval interaction moving window partial least squares (iMWPLS) is used...The content of this RSS Feed (c) The Royal Society of […]Shuming Lan
- Dual-Mode CRISPR/Cas12a-Mediated Alkaline Phosphatase Detection (CAD) Biosensor January 15, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01195G, PaperDaqi Chen, Baian Zhu, Yachunyue Zhou, Zhezhi Fang, Zhuobin Zhu, Chaozhan Chen, Teng ShenAlkaline phosphatase (ALP), a crucial biomarker for hepatobiliary disorders, bone diseases, and cancer progression, demands ultrasensitive detection methods to meet clinical diagnostic requirements. Current methodologies predominantly depend on single-readout mechanisms,...The content of this RSS Feed (c) […]Daqi Chen
- Dual-Organelle-Targeted Near-Infrared Carbon Dots for Visualizing Glucose Dynamics in Cellular Energy Metabolism with Potential in Exercise Physiology January 15, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01904D, PaperXiaodong Cheng, XiaoWen DuanAccurate monitoring of cellular energy metabolism is crucial for understanding exercise physiology and optimizing athlete training and recovery. However, current assessments mainly rely on macroscopic indicators such as heart rate...The content of this RSS Feed (c) The Royal Society of ChemistryXiaodong Cheng
- A novel 3D-CB/HEC-CH@Cu hybrid electrode for sensitive and rapid ammonia nitrogen detection in environmental water January 14, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01860A, PaperPablo Henrique Silva Martins, Hugo Leonardo Souza Lara Leão, Polyana Fernandes PereiraIn this paper, a sensor based on 3D-printed carbon black (3D-CB), and coated with a hydroxyethylcellulose/chitosan (HEC/CH) bilayer and finished by copper electrodeposition, is presented for the electrochemical sensing of...The content of this RSS Feed (c) The Royal […]Pablo Henrique Silva Martins
- Smart Recognition of Chemical Contaminants in Food: Experimental and Computational Perspectives on MIP-Based Sensors January 14, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY02019K, Critical ReviewSamra Ashraf, Ghulam Mustafa, Khalid Pervaiz, Ataf A Altaf, Muhammad HamayunThe growing concern about chemical contaminants in food has enhanced the need for rapid, selective, and cost-efficient sensing technology. Molecularly imprinted polymers (MIPs) have emerged as potential artificial sensing elements...The content of this RSS Feed (c) The Royal […]Samra Ashraf
- Identification of key aroma components in Rose Lujiu from different origins based on e-nose, e-tongue, GC-MS and GC-IMS January 14, 2026Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY01454A, PaperJun-Xia Li, Min Gong, Chao Ma, Yao-Yao Li, Ling-Xiao Liu, Bin Wang, Jin-Jing Ren, Sheng-Ming Lei, Yun-Guo LiuAroma analysis was conducted on the volatile compounds in Rose Lujiu (RL). Four volatile compounds can serve as indicators to differentiate RL.To cite this article before page numbers are assigned, use the […]Jun-Xia Li
- Acrolein-integrated ESIPT probe for NIR fluorescence detection of cysteine with ultrafast response and sub-nanomolar sensitivity January 13, 2026Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY01661D, PaperShuangying Su, Binjie Zhang, Shijun Chen, Cailing Fan, Xianzhe Yu, Wei Shu, Weijie Chi, Chaoyuan ZengCysteine (Cys) is an essential sulfur-containing amino acid in the human body and is involved in many important physiological processes.To cite this article before page numbers are assigned, use the DOI form of citation […]Shuangying Su
- Accelerated Green Analysis of Phyllanthi Fructus by One Dimensional Convolutional Neural Network (1D CNN) Modeling of Time-Contracted HPLC Fingerprints January 13, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01938A, PaperShamukaer Alimujiang, Shubo Guo, Cunhao Li, Xiaohui Fan, Wenlong LiTo address the lengthy analytical cycles and high solvent consumption of conventional HPLC, this study focused on Phyllanthi Fructus (PF) and, by optimizing gradient elution conditions, established a time contracted...The content of this RSS Feed (c) The Royal Society of […]Shamukaer Alimujiang
- A novel low-rank coal-based CDs for the detection of Fe3+ January 13, 2026Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01773D, PaperWenwen Wu, Xiang Han, Siyu Zhang, Lele Li, Meili Du, fuxin ChenIn this study, a novel type of coal-based carbon dots (CDs) was synthesized using Inner Mongolia lignite as the carbon source and H2O2 as the oxidant agent, and it was...The content of this RSS Feed (c) The Royal […]Wenwen Wu
- A Bst-driven Cas12a cascade amplification strategy for microRNA detection January 12, 2026Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY01957E, PaperQuanzhong Xu, Mingfang JiAn fluorescence platform combining Bst DNA polymerase-assisted target recycling with CRISPR/Cas12a-mediated signal amplification is proposed for the highly sensitive and selective detection of microRNA-21.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The […]Quanzhong Xu
- Laser-induced fluorescence for detecting thermal degradation of a biological fluid model: a systematic study applying chemometrics January 12, 2026Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY01611H, PaperOmnia Hamdy, Ashraf S. Abdel HalimLaser-induced fluorescence spectroscopy combined with chemometric analysis enables sensitive discrimination of thermally treated milk by capturing heat-induced changes in intrinsic fluorophores.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal […]Omnia Hamdy
- A novel molecular imprinted quartz crystal microbalance sensor for fenamiphos determination based on boron-sulphur co-doping ultra-thin graphitic carbon nitride incorporated Cu-MOF January 20, 2026