RSC – Anal. Methods latest articles- Ambient Ionization Mass Spectrometry for Rapid Screening of Illegal Adulteration in Traditional Chinese Medicines: A Review December 23, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY02001H, MinireviewFangliang Yang, Wei Shen, Jingjing YingIllegal adulteration of Traditional Chinese Medicines has become a critical global safety concern, driven by the covert addition of synthetic pharmaceuticals such as phosphodiesterase type five inhibitors, anorectic agents, nonsteroidal...The content of this RSS Feed (c) The Royal Society of ChemistryFangliang Yang
- A Pt-loaded magnetic covalent organic framework with dual enzymatic activity for nanozyme-linked immunosorbent assay of SEB December 23, 2025Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY01674F, PaperHuiping Feng, Yue Sun, Jiang Wang, Jiwei Xu, Xihui Mu, Bin Du, Zhaoyang Tong, Bing LiuA tailored-pore, high-surface-area COF improves the dispersion, stability, and size control of Pt NPs. Their excellent dual enzyme-like activity enables a highly stable, specific, and sensitive sensing platform.To cite this article before page numbers […]Huiping Feng
- Establishment and evaluation of the detection method for human adenovirus and its subtypes based on RAA-LFD technology December 23, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01439E, PaperMengru Liu, Guiqi Hu, Yu Yu, Qingyang Sun, Chunli Yang, Mengyu Lv, Yue Wang, Yuzhu Dai, Jun ChengAbstract: In this research, we developed a rapid assay for detecting human adenovirus (HAdV) and its prevalent subtypes (including HAdV3, HAdV4, HAdV7, HAdV14, HAdV11, and HAdV55) based on recombinase-mediated isothermal...The content of […]Mengru Liu
- A fast method based on programmed temperature vaporization-mass spectrometry for the quantification of 17α-ethinylestradiol and drospirenone in contraceptive formulations December 23, 2025Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY01770J, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Pablo Álvarez Alonso, Iria González-Mariño, Miguel del Nogal Sánchez, Ana Ballester-Caudet, Encarnación Rodríguez-Gonzalo, José Luis Pérez PavónA rapid method has been developed for the determination of 17α-ethinylestradiol and drospirenone in contraceptive formulations.To cite this […]Pablo Álvarez Alonso
- Analytical methods for glycoRNA detection: A systematic review December 23, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01539A, MinireviewSijia Sun, Qian Liu, Zhen LiuGlycosylated RNAs (glycoRNAs) are a groundbreaking discovery in glycobiology, extending the diversity of known glycoconjugates beyond proteins and lipids. Accumulating evidence indicates their pivotal roles in cellular communication, immune regulation,...The content of this RSS Feed (c) The Royal Society of ChemistrySijia Sun
- Construction and validation of a method for detecting DPP-IV activity and tissue distribution in C57 mice based on fluorescent probe December 22, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01757B, PaperBin Wang, Zi-Qiang Chen, Cong Hu, Si-Man Wang, Xingkai Qian, Liwei Zou, Ling YangDipeptidyl peptidase-IV (DPP-IV) is critical for drug metabolism and physiological regulation. In terms of species differences of DPP-IV, mouse an d human share a high degree of similarity，it is usually...The content of this RSS Feed (c) […]Bin Wang
- Establishment of the new dispersive solid phase microextraction method with green adsorbent CaAl-LDH hybrid with g-C 3 N 4 utilised for the determination of Pb 2+ in Instant cup noodles and environmental samples December 22, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01871D, PaperMuhammad Balal Arain, Abdul Niaz Abdul Niaz, Mustafa SoylakAdsorbents with a significant adsorption capacity and high selectivity are required to identify and eliminate heavy metal ions from the under study environmental and food samples. For this purpose, in...The content of this RSS Feed (c) The Royal Society of ChemistryMuhammad Balal Arain
- Geographical origin traceability analysis of camellia oil based on headspace gas chromatography-ion mobility spectrometry and chemometrics December 22, 2025Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY01886B, PaperShaojie Wu, Haojie Wu, Jirong Wu, You Zhou, Tingting Han, Daoming Chen, Jianbo Qiu, Xin Liu, Jianrong Shi, Jianhong Xu, Guanghui ShenGC-IMS combined with chemometric algorithms enables accurate identification of the geographical origin of camellia oil at both provincial and city levels, providing reliable technical support for geographical indication […]Shaojie Wu
- Gamma-hydroxybutyric acid (GHB) derivatization with N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide (EDC): LC-HRAM-Orbitrap-MS characterization of GHB and deuterated GHB derivatives and application to blood, urine, and hair analysis December 22, 2025Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY01461A, PaperGiampietro Frison, Arianna Negro, Flavio Zancanaro, Samuela Frasson, Gianpaola Tedeschi, Camilla Vigato, Giorgia MioloThis paper describes a new analytical approach for determining gamma-hydroxybutyric acid (GHB) in biosamples using liquid chromatography-mass spectrometry (LC-MS) following derivatization with N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide (EDC).To cite this article before page numbers are assigned, use the DOI form […]Giampietro Frison
- Targeted Metabolomics of Nucleotide Intermediates for Biomarker Discovery in Acute Kidney Injury December 20, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01324K, PaperXiaona Li, Sihan Wang, Zhini Liu, Yuqi Jia, Xiuli Su, Changqing Yang, Qinggang Ge, Libo Zhao, Rongsheng ZhaoAcute kidney injury (AKI) is a common syndrome among critically ill patients with high incidence and high mortality, characterized by elevated serum creatinine (SCr) and uric acid (UA) levels. Given...The content of […]Xiaona Li
- Establishment and Application of a Method for Detecting Tetracycline Antibiotics in Milk Based on AlphaLICA Technology December 19, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01720C, PaperDian Li, Yun Chen, Shangbin Kao, Canlong Yan, Tianyu Zheng, Yuan Qin, Xiumei Zhou, Xiang Shao, Biao HuangAddressing the challenges of strong matrix interference, cumbersome procedures, and urgent demand for on-site rapid detection in the analysis of tetracycline antibiotics (TCs) residues in milk, this study aims to...The content of […]Dian Li
- A robust approach of QuEChERS combined with GC-MS technique for determination of three typical liquid crystal monomers in mouse serum and various tissues December 19, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01706H, PaperWei Chen, Xuanyu Hong, Huachun Liu, Ruifang FanLiquid crystal monomers (LCMs) are emerging organic pollutants to which humans are chronically exposed at low doses. Accurate quantification of LCMs in biological matrices remains challenging due to their low...The content of this RSS Feed (c) The Royal Society of ChemistryWei Chen
- Determination of paraquat in drinking water by HPLC-UV using large-volume injection and a superficially porous particle HILIC column December 18, 2025Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY01675D, PaperIsmael dos S. Belmonte, Tânia M. Pizzolato, Mariana R. GamaA large-volume injection approach on a superficially porous HILIC column enabled the direct HPLC-UV determination of paraquat in tap water at µg L−1 levels, eliminating the need for an SPE preconcentration step.To cite this article before page numbers are assigned, […]Ismael dos S. Belmonte
- A silica coated AgNCs fluorescence sensor for detection of cefixime in pharmaceutical products and biological samples December 17, 2025Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY01590A, PaperRui Tian, Jiamin Chai, Yuhui Yang, Rui Zhang, Hua Yang, Xuehua Sun, Haoyu LiSilica coating markedly improves the fluorescence and sensing performance of Ag NCs, whose composite (Ag NCs/SNPs) acts as a sensitive turn-off probe for Cfx detection in pharmaceuticals and biological samples.To cite this article before page numbers […]Rui Tian
- Recent progress in metal–organic gels for fluorescent sensing: design, mechanisms, and applications December 16, 2025Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY01920F, MinireviewXiao-Han Yuan, Xin-Yue Meng, Shuo Zhang, Wen-Sheng Liu, Jian-Hua ZhangThis minireview summarizes the latest MOG-based fluorescent sensing advances via a “foundation-design-mechanism-application” framework, providing a comprehensive reference for researchers designing, optimizing and translating these platforms.To cite this article before page numbers are assigned, use the DOI form of citation above.The […]Xiao-Han Yuan
- A Novel Platform using a Regenerable SDS-Functionalized Membrane with AF4-DAD-MALS for Online Enrichment and Detection of Polydisperse Nanoplastics in Biological Samples December 16, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01731A, CommunicationXing-Ling Luo, Aobo Geng, Yingting Wu, Zhen Mao, Xiaodan Zhang, jin Cai, Peili HuangIn view of the significance and urgency of elucidating the internal exposure toxicity and transport mechanisms of nanoplastics (NPl) in organisms for assessing their health risks, we developed a novel...The content of this RSS Feed (c) […]Xing-Ling Luo
- Multimodal detection of high-risk HPV oncogenic transcripts using a branched hybridization chain reaction amplification method December 16, 2025Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY01638J, PaperVictoria Mwaeni, Dorothy Nyamai, Samoel Khamadi, Sophia Musenjeri, Mutinda Cleophas KyamaA branched hybridization chain reaction amplification method for multimodal detection of high risk HPV oncogenic transcripts. The bHCR assay is a versatile diagnostic strategy with adaptability to other molecular biomarkers.To cite this article before page numbers are assigned, use […]Victoria Mwaeni
- Visualization of the distribution of carbendazim on the arabidopsis leaf surface by VUV-postionization mass spectrometry December 16, 2025Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY01242B, PaperWuyi Nie, Anan Li, Xueqing Shang, Qiao Lu, Yongjun HuVisualization of the distribution of carbendazim on the arabidopsis leaf surface by VUV-postionization mass pectrometry.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of […]Wuyi Nie
- Development of an AQbD driven HPLC method for the simultaneous estimation of caffeine and misoprostol in nanoparticle formulations December 16, 2025Anal. Methods, 2026, Advance ArticleDOI: 10.1039/D5AY01373A, PaperNitasha Chauhan, Shiv Kumar, Shailendra Singh Rana, Shruti Chopra, Amit BhatiaThis graphical abstract depicts the HPLC-based simultaneous estimation of caffeine and misoprostol using, AQbD, followed by quantitative analysis of both drugs in chitosan based nanoparticles.To cite this article before page numbers are assigned, use the DOI form of citation […]Nitasha Chauhan
- Zn-MOF-8-Based Nitrogen-Doped Mesoporous Carbon/Multi-Walled Carbon Nanotube-Modified Electrode for Highly Sensitive Detection of Isoquercitrin December 16, 2025Anal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01823D, PaperWei Liu, Zi Li, Siqi Ding, Pengli Zhang, Zimo Zhang, Hongfang Li, Qiongyao Zeng, Yanhua Sun, Pingping Huang, Zhiyong ZhuIn this study, Nitrogen-doped mesoporous carbon (NMC) was synthesized using Zn-MOF-8 as a template, followed by further reaction with multi-walled carbon nanotube (MWCNTs) to prepare the NMC/MWCNTs nanocomposite. Characterization of...The […]Wei Liu
- Ambient Ionization Mass Spectrometry for Rapid Screening of Illegal Adulteration in Traditional Chinese Medicines: A Review December 23, 2025
