RSC – Food Funct. latest articles- The intricate microbial-gut-brain axis in Alzheimer's disease: A review of microbiota-targeted strategies September 24, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO03139G, Review ArticleShu Zhang, Zhenghao Wu, Shuling Zhang, Yuehang Ru, Qinwen Wang, Haoxiang Tong , Qihan Qin, Qingmin Yan, Ziwei Li, Guoqing WuThe microbiota-gut-brain axis (MGBA) has emerged as a potential focus for the enhancement of cognitive abilities and the improvement of Alzheimer's disease (AD). Probiotics and prebiotics can improve […]Shu Zhang
- Modulation of hyperglycemia, insulin resistance responses and gut microbiota composition in type 2 diabetic mice by capsicum residue soluble dietary fiber September 24, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO01390A, PaperYaxing Feng, Wenxiu Wang, Xiangyun Liu, Fengjuan Wang, Yuwei Dong, Qianyun Ma, Jianfeng SunCapsicum residue soluble dietary fiber demonstrated hypoglycemic effects in type 2 diabetic mice by improving glucose homeostasis and insulin resistance, enhancing short-chain fatty acid levels, and ameliorating gut microbiota composition.To cite this article before page numbers […]Yaxing Feng
- Extraction, Characterization, and Anti-Aging Evaluation of Flavonoids from Citrus reticulata ‘Zhangshuensis’ September 22, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO02218E, PaperJiapan Gan, Jiayan Xie, Xin Xu, Jiahao Ai, Sisi He, Jiafen Zou, Qiang Yu, Hongli Jin, yanfang liu, Xinmiao LiangZhangTouHong (ZTH), highly valuable edible-medicinal resource rich in bioactive flavonoids, lack of chemical composition and biological activities studies. In this work, a preparation process was developed to prepare flavonoid multi-components...The […]Jiapan Gan
- Aronia melanocarpa anthocyanins attenuate light-induced retinal damage via enhancing photoreceptor cell function and anti-inflammatory effects. September 22, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO02930A, PaperMingjun Ye, Long Zuo, Xusheng Li, Dawei Sun, Xiaohong Xu, Shengquan Huang, Weibin BaiProlonged exposure to excessive light causes retinal photodamage, leading to structural and functional impairment of the retina through pathogenic mechanisms involving oxidative stress, inflammatory responses, and disruption of cellular homeostasis....The content of this RSS Feed (c) […]Mingjun Ye
- Anthocyanin-enriched purple potato flour modulates gut microbiota and short-chain fatty acids to prevent hypertension: insights from preclinical models and mendelian randomization analysis September 22, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO03028E, PaperYixin Ye, Yingyi Deng, Ruolan Yi, Yexin Qin, Tong Zhang, Jinlian Huang, Lini Nong, Guangqiu Qin, Hai Li, Xu Zheng, Lihong ZhouPurple potato diet uniquely modulates gut microbiota, increases SCFAs, and lowers blood pressure via multi-mechanism action, demonstrating whole-food safety and efficacy.To cite this article before page numbers are […]Yixin Ye
- Green tea prepared with daily infusion style prevents non-alcoholic fatty liver disease by targeting intestinal lipid absorption, hepatic lipid metabolism and gut microbiota composition September 21, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D4FO05479B, PaperTsukasa Oriita, Satoshi Chogahara, Kozue Sakao, Qian Lin, Daichi Ijiri, De-Xing HouNon-alcoholic fatty liver disease (NAFLD) is closely linked to metabolic disorders and is characterized by excess fat accumulation in the liver. Although drinking green tea has been reported to have...The content of this RSS Feed (c) The Royal […]Tsukasa Oriita
- Synergistic protective effects of β-glucan and Lactobacillus johnsonii NSP009 in ulcerative colitis September 21, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO02391B, PaperShanshan Zhang, Yonggan Sun, Linlin Gao, Ziyi Zhang, Yongkang Yu, Dechang Xu, Shaoping Nieβ-glucan and L. johnsonii NSP009 synergistically ameliorate colitis.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of ChemistryShanshan Zhang
- Previous title: Inhibition of ex vivo VEGF-induced angiogenesis by tyrosol and hydroxytyrosol present in Mediterranean diet foods: Quantitative three-dimensional mouse aortic ring model Current version title: Inhibition of ex vivo VEGF-induced angiogenesis by tyrosol and hydroxytyrosol: Quantitative three-dimensional mouse aortic ring mode September 21, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO02820E, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Ana B. Cerezo, Marta Gallardo Fernández, Álvaro Santana-Garrido, Ruth Hornedo-Ortega, CARMEN VAZQUEZ, Ana-Maria Troncoso, Maria Carmen Garcia-ParrillaMediterranean diet foods such as olives, virgin olive oil and wine are sources of tyrosol (TOL) and hydroxytyrosol […]Ana B. Cerezo
- Postprandial metabolism of a reduced-fat meat product with added silicon from diatomaceous earth. A pilot randomized controlled four-way assay in humans September 21, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO00973A, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.M. Pilar Vaquero, M. Dolores Alvarez, Belén Zapatera, Arancha Saiz, Susana CofradesThe use of silicon (Si) in functional foods is innovative. Because meat products are versatile, nutritious and highly accepted by the population, in […]M. Pilar Vaquero
- Amelioration effects of Cajanus cajan extracts and active ingredient pinostrobin on hyperuricemia and related kidney injury September 18, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO01806D, PaperXiancai Li, Wanjie Yu, Liyuan Yao, Fen Liu, Yongqing Li, Binghong Xiong, Jin Xie, S. X. QiuXanthine oxidase (XO) is an effective therapeutic target for the treatment of hyperuricemia-related diseases. Cajanus cajan (L.) Millsp. (pigeonpea) is a traditional medicine and food homologous plant. Here, we found...The content of this […]Xiancai Li
- Mung bean (Vigna radiata L.) ethanol extracts alleviate alcoholic liver injury with modulation of gut microbiota and spermidine elevation September 18, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO02499D, PaperYixin Liu, Yi Ruan, Anhui Zhao, Zhiying Bian, Jing Bai, Shuqi Niu, Songtao Wang, Zhangjun Huang, Xiaonan Cao, Caihong Shen, Sijing Liu, Jin-Lin GuoThe pathophysiology of alcoholic-associated liver disease (ALD) is multifaceted. Utilizing the gut-liver axis framework and integrated multi-omics approaches, this study systematically evaluated the therapeutic potential of […]Yixin Liu
- PREVENTIVE EFFECT OF SHEEP MILK ON DSS-INDUCED COLITIS IN MICE: MODULATION OF GUT MICROBIOTA AND INFLAMMATORY RESPONSES September 17, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO02200B, PaperNASEER AHMAD, Zhongshi Zhu, TINGTING CHU, Jiaxin Liu, LI DHANNI, YUE JIANG, Lei Zhang, HAO YUAN, YUXUAN SONGThis study explores the potential of sheep milk (SM) as a therapeutic treatment for ulcerative colitis (UC) in mice, focusing on its dose-dependent effects. Sheep milk, known for its rich...The content of […]NASEER AHMAD
- Effects of anthocyanins on human health: an umbrella review of systematic reviews and meta-analyses September 17, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO02803E, Review ArticleXingyu Liu, Keyang Ge, Haiyan Shi, Zhiyuan Yao, Zhihua ZhangSystematic evaluation of the evidence on anthocyanins' health effects through an umbrella review of systematic reviews and meta-analyses.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) […]Xingyu Liu
- Effects of dietary energy restriction of ultra-processed foods compared to a generic energy restriction on the intestinal microbiota of individuals with obesity: a secondary analysis of a randomized clinical trial September 17, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO02449H, PaperAna Debora Santos de Oliveira, Nayara Gomes Graciliano, Dafiny Rodrigues Silva, Mateus de Lima Macena, André Eduardo da Silva-Júnior, Micnéias Roberth Pereira, João Victor Laurindo Santos, Maria Bárbara Galdino Silva, Karine Maria Moreira Almeida, Déborah Tenório da Costa Paula, Débora Cavalcante Ferro, Guilherme César Oliveira de Carvalho, Marianna Victória […]Ana Debora Santos de Oliveira
- Anti-obesity effect of unsaponifiable matter from hemp seed in 3T3-L1 adipocytes and high-fat diet-induced obese mice September 17, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO02231B, PaperYeji Kwon, Unyong Kim, Sang Beom Han, Samuel Park, Junsoo Lee, huijin heo, Hui-Jeon Jeon, Dong-Hee Lee, Joonhyuk Suh, Jeehye SungThe favorable lipid profile of hemp seed could be a potential source of unsaponifiable matter rich in fat-soluble phytochemicals such as phytosterols, vitamin E, and cannabidiol (CBD). Despite its […]Yeji Kwon
- Gut microbial clusters in children show different cardiometabolic responses to wholegrains – a post hoc analysis of a randomized wholegrain trial in children September 16, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO02026C, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Marie B. M. Madsen, Lars H. Christensen, Dennis S. Nielsen, Yichang Zhang, Henrik M. Roager, Lotte Lauritzen, Rikard Landberg, Camilla T. DamsgaardGut microbial clusters in children modified the effects of wholegrain intake on body […]Marie B. M. Madsen
- Early changes in exosomal microRNAs after a one-week low-calorie diet predict sustained glycaemic and weight outcomes in patients with type 2 diabetes September 15, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO02781K, PaperSujing Wang, Shuxiao Shi, Deshan Wu, Kexin Li, Guangrui Yang, Ruijie Qi, Lan Xu, Nannan Feng, Victor W. Zhong, Xihao DuA one-week low-calorie diet rapidly remodeled human plasma exosomal miRNAs. Thirty-two miRNAs highlight metabolic and vascular pathways, offering a signature for early intervention tracking.To cite this article before page […]Sujing Wang
- Cholesterol-lowering effects of phytosterol combined with phosphatidylcholine and their mechanism of action in hypercholesterolemic rats September 15, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO02852C, PaperYuan Chen, Lili Fu, Yanyan Wang, Ranran Chang, Aiguo MaThe potential efficacy and underlying mechanisms of phosphatidylcholine (PC) combined with phytosterol (PS) for regulating hypercholesterolemia in rats fed a high cholesterol diet (HCD) were investigated.To cite this article before page numbers are assigned, use the DOI form of citation […]Yuan Chen
- Ussurian pear extract alleviates acute alcoholic liver injury by enhancing alcohol metabolism and suppressing hepatic oxidative stress and inflammation in rats September 15, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO02498F, PaperHaifeng Shao, Chenzi Lyu, Yang Wang, Zi-eum Im, Juyeon Jeong, So-Yeon Gil, Yong-Ki Park, Hyo Won JungUssurian pear extract alleviates acute alcoholic liver injury by enhancing ethanol metabolism, activating the KEAP1/Nrf2/HO-1 antioxidant pathway, and inhibiting NF-κB/MAPK-mediated inflammation.To cite this article before page numbers are assigned, use the DOI form […]Haifeng Shao
- The Impact of (Poly)phenol-Rich Foods and Extracts on Flow-Mediated Dilation (FMD): A Narrative Review September 14, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO01106J, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Brian Óg Murphy, Holly Neill, Niamh Magee, Erika J. Rosbotham, Kirsty Pourshahidi, Patrick Richardson, Camille Pouchieu, David Gaudout, Sumantra Ray, Letizia Bresciani, Daniele Del Rio, Ana Rodriguez-Mateos, Alan Crozier, Chris GillCardiovascular disease (CVD) […]Brian Óg Murphy
- The intricate microbial-gut-brain axis in Alzheimer's disease: A review of microbiota-targeted strategies September 24, 2025
