RSC – Food Funct. latest articles- In vitro simulated digestion and fermentation of Lithocarpus litseifolius [Hance] Chun green tea polysaccharides and their modulation of the gut microbiota December 12, 2025Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO04379D, PaperQingying Luo, Xuewei Liao, Lijia Zhang, Zhengfeng Fang, Hong Chen, Bin Hu, Yuntao Liu, Zhen ZengLithocarpus litseifolius [Hance] Chun is rich in bioactive polysaccharides, which have attracted substantial research attention due to their ability to effectively modulate the composition and function of the gut microbiota.To cite this article before […]Qingying Luo
- Chrysanthemum 3,5-O-dicaffeoylquinic acid ameliorates mice alcoholic liver injury by suppressing TLR-4/NF-κB pathway and restoring glycerophospholipid homeostasis December 12, 2025Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO02695D, PaperYi-Long Ma, Zhi Li, Qian-Lan Wu, Jing Li, Xin Guo, Tian-Le Mao, Kiran Thakur, Zhao-Jun Wei3,5-O-Dicaffeoylquinic acid (3,5-DCQA) from edible Gongju chrysanthemum has demonstrated protective effects against alcoholic hepatocyte injury in our previous study. However, the specific effects and mechanisms of 3,5-DCQA in a mouse...The content of this RSS […]Yi-Long Ma
- Hypoglycemic effects under in vitro digestion of brewer's spent yeast β-glucan concentrate added to a rice extrudate December 12, 2025Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO03588K, PaperMarilin E. Aquino, Olga Martínez-Augustin, Fermín Sánchez de Medina, Franco Van de Velde, Silvina R. Drago, Raúl E. CianPotential hypoglycemic properties of brewer's spent yeast β-glucan concentrate alone or incorporated into rice extrudates were studied through the inhibition of DPP-IV, α-amylase, and α-glucosidase enzymes after simulated digestion.To cite this […]Marilin E. Aquino
- Oyster Hydrolysate via Dynamic Enzymolysis Ameliorates Male Sexual Dysfunction in Mice December 11, 2025Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO03860J, PaperChunli Xu, Yuhong Huang, Junran Yin, Chengfei Liu, Dongyu An, Shiming Deng, Guijin LiuMale sexual dysfunction (MSD) poses a substantial global health burden, with current pharmacotherapies often limited by adverse effects, necessitating safer, natural alternatives. This study investigates the therapeutic potential of oyster...The content of this RSS Feed (c) […]Chunli Xu
- Precision probiotic development based on gut microbial biomarkers: from mechanistic insights to clinical translation December 10, 2025Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO01850A, Review ArticleLing Li, Teng Yan, Ruonan Yan, Xiaoqun Zeng, Qiwei Du, Zhen Wu, Daodong PanMultifactorial gut microbiota heterogeneity necessitates precision intervention. Multidimensional data enables biomarker discovery. Predictive modeling + optimized delivery drive precision probiotics.To cite this article before page numbers are assigned, use the DOI form of citation above.The […]Ling Li
- Metabolic benefits of 1,3-diacylglycerol in type 2 diabetes mellitus and its association with gut microbiota-derived SCFAs-GPR41-GLP-1 signaling December 9, 2025Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO03164H, PaperJiaomei Li, Hao Wang, Jiekai Yang, Yicheng Wang, Guo Jia, Jiaojiao Gu1,3-Diacylglycerol (1,3-DAG) is a dietary lipid with known lipid-lowering effects, yet its role in type 2 diabetes mellitus (T2DM) and gut microbiota regulation remains unclear. This study investigated the effects...The content of this RSS Feed (c) The Royal […]Jiaomei Li
- Polyphenols from Blumea laciniata Alleviated Neurotoxicity induced by BPA on Caenorhabditis elegans and its Application in Yogurt December 9, 2025Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO04472C, PaperSiyuan Luo, Chenhao Shi, Jiayi Tang, Kejin Zheng, Huajun Zhao, Haixin QinThe widespread use of bisphenol A (BPA) poses potential toxic risks to humans, with its neurotoxicity being particularly concerning. However, there are currently no targeted mitigation strategies for this toxicity....The content of this RSS Feed (c) The Royal […]Siyuan Luo
- Bifidobacterium animalis subsp. lactis Bbm-19 ameliorates insomnia by remodeling the gut microbiota and restoring γ-aminobutyric acid and serotonin signaling December 9, 2025Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO04374C, PaperQiong Wu, Guangqi Gao, Lai-Yu Kwok, Jiaqi Qiao, Ziqing Wei, Qiuwen He, Zhihong SunInsomnia is associated with dysregulation of the gut-brain axis, yet microbiometargeted interventions remain underexplored. In this study, we investigated the effects of Bifidobacterium animalis subsp. lactis , a strain isolated...The content of this RSS Feed (c) […]Qiong Wu
- Ameliorative potential of rice protein hydrolysates prepared through high-pressure processing against diabetic cardiomyopathy December 9, 2025Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO01477H, PaperYu-Tsung Cheng, Ping-Hsiu Huang, Yung-Jia Chan, Wen-Chien Lu, Po-Hsien LiVarious functional foods, including meal replacements and nutritional supplements, are available to consistently regulate blood glucose levels in patients with type 2 diabetes mellitus (T2DM).To cite this article before page numbers are assigned, use the DOI form of citation above.The […]Yu-Tsung Cheng
- Microbiomics and metabolomics insights into the mechanism of egg yolk phosphatidylcholine enhancing intestinal immunity December 8, 2025Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO02959G, PaperYunpeng Wen, Shuping Chen, Teng Wei, Na Wu, Yao Yao, Lilan Xu, Jihua Mao, Yan Zhao, Yonggang TuEgg yolk phosphatidylcholine (EYPC), the most vital functional lipid in egg yolk, enhanced intestinal immunity through regulating gut microbiota and fecal metabolic profiles.To cite this article before page numbers are assigned, use […]Yunpeng Wen
- Heyndrickxia coagulans as a next-generation probiotic: current evidence and future perspectives December 8, 2025Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO03559G, Review ArticleSihan Ke, Zixia Chen, Yutong Qi, Jiantang Zhang, Qizhu Chen, Jun Chen, Huaben BoHeyndrickxia coagulans, a spore-forming probiotic, has garnered significant attention due to its exceptional tolerance to gastric acid and heat, alongside its multifaceted therapeutic potential.To cite this article before page numbers are assigned, use the DOI […]Sihan Ke
- Evaluating Casein Ingredients in Infant Formula Using Newborn Pigs as a Model for Infants December 8, 2025Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO03498A, PaperMengjia Li, Kristine Holgersen, Søren Drud-Heydary Nielsen, Anita Phuong Vy Le, Pingping Jiang, Luiza Patrycja Morawska, Ann Bjørnshave, Stine Brandt Bering, Nina Poulsen, Per Torp Sangild, Lotte Bach LarsenBackground: Relative to whey protein, the role of casein in infant formula remains underexplored. We investigated the effects of modified micellar […]Mengjia Li
- The effects of phenolic acid supplementation on intestinal barrier function: a review December 8, 2025Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO03351A, Review ArticleLi Xia, Xiulian Lin, Yuanjiao Zhou, Yamei Li, Yingyan Liao, Yan Lin, Limei Lin, Ping Wu, Jingchen XieDamage to the intestinal barrier is a common pathological feature of several diseases, and phenolic acids can repair its damage through multiple mechanisms.To cite this article before page numbers are assigned, […]Li Xia
- Correction: A Ganoderma atrum polysaccharide alleviated DSS-induced ulcerative colitis by protecting the apoptosis/autophagy-regulated physical barrier and the DC-related immune barrier December 8, 2025Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO90109J, Correction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Bing Zheng, Mengxi Ying, Jianhua Xie, Yi Chen, Yudan Wang, Xiaomeng Ding, Jiaqian Hong, Wang Liao, Qiang YuTo cite this article before page numbers are assigned, use the DOI form of citation above.The content […]Bing Zheng
- Correction: Inhibition of pro-atherogenic trimethylamine production from choline by human gut bacteria is not determined by varying chlorogenic acid content in highbush blueberries December 8, 2025Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO90108A, Correction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Ashley M. McAmis, Michael G. Sweet, Sydney Chadwick-Corbin, Juanita G. Ratliff, Molla Fentie Mengist, Nahla V. Bassil, Pon Velayutham Anandh Babu, Massimo Iorizzo, Andrew P. NeilsonTo cite this article before page numbers are assigned, […]Ashley M. McAmis
- Effect of κ-carrageenan with different molecular weights and its acetylated derivatives on the structure and metabolites of intestinal flora December 5, 2025Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO03102H, PaperShiqi Shen, Cailing Tong, Yujia Ou, Tao Hong, Zhipeng Li, Yanbing Zhu, Hui Ni, Zedong Jiang, Mingjing ZhengThe digestive fermentation characteristics of κ-carrageenan with different molecular weights and its acetylated derivatives were investigated through the changing rules of intestinal flora and metabolites. The results showed that κ-carrageenan...The content of […]Shiqi Shen
- Chemical Quality Profile and Bioactivities of “Hongyin” Tea, a Purple-budded Cultivar from Eastern Guangdong December 4, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO04000K, PaperShuqia Ding, Linfen He, Wenjing Pan, Qingqing Ye, Hanzhong Ye, Zhonghua Liu, Shuxian Cai‘Hongyin’ (HY) is a purple-budded Camellia sinensis cultivar from eastern Guangdong whose chemistry and bioactivities are not fully defined. We integrated sensory and compositional assays (catechins, caffeine, anthocyanins) with UPLC–MS/MS...The content of this RSS Feed (c) […]Shuqia Ding
- Fucoxanthin prevents septic cardiomyopathy by targeting BRD2 in M1-polarized macrophages December 4, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO04244E, PaperXuechun Sun, Tingwei Chen, Xiqing Zhang, Huali Meng, Yanqi Hu, Fang Zheng, Yufeng Chu, Lei Sun, Hao WuSeptic cardiomyopathy (SCM) leads to heart failure with few effective approaches for its intervention. Fucoxanthin (FX) possesses anti-inflammatory capacity, but its effect on SCM remains unknown. Here we report that...The content of […]Xuechun Sun
- Role of lycopene from tomato on cardiovascular risk: an umbrella review of systematic reviews and meta-analyses of intervention studies December 4, 2025Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO04213E, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Yea-eun Nam, In-Guk Hwang, Hwan-Hee JangDaily lycopene intake (5–30 mg) from tomatoes consistently reduces blood pressure with high certainty. Despite variability by cultivar and processing, daily lycopene requirements can generally be met by […]Yea-eun Nam
- Selenium-Containing Peptides Attenuating Pb-Induced Memory Impairment through Molecular Chelation and microRNA-Mediated Signaling December 2, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO04343C, PaperFengjiao Fan, Nanlong Li, Wenqian Tang, Zhiyin Xiao, Xiaoyi Jiang, Peng Li, Jian Ding, Qinlu Lin, Yong FangLead (Pb) accumulation in the hippocampus and subsequent induced oxidative stress contribute to memory impairments, highlighting the hippocampus as a primary target for Pb neurotoxicity. Selenium-containing peptides TSeMMM and SeMDPGQQ...The content of […]Fengjiao Fan
- In vitro simulated digestion and fermentation of Lithocarpus litseifolius [Hance] Chun green tea polysaccharides and their modulation of the gut microbiota December 12, 2025