RSC – Food Funct. latest articles- Bifidobacterium longum subsp. infantis CCFM1269 alleviates neonatal maternal separation-induced colic in rats by regulating serotonin metabolism, NGF/TrkA signaling pathway and gut microbiota June 26, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D6FO02711C, PaperHongyu Wang, Renqiang Yu, Catherine Stanton, R. Paul Ross, Jianxin Zhao, Wei Chen, Bo YangInfantile colic (IC), a common functional gastrointestinal disorder in early life, affects approximately 20% of infants worldwide and is associated with long-term health risks; nevertheless, effective interventions remain limited. This...The content of this RSS Feed […]Hongyu Wang
- Moderate consumption of a polyphenolic-enriched wine attenuates alcohol-associated alterations in hepatic biomarkers in overweight subjects: a randomized clinical trial June 25, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D6FO01211F, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.I. Urquiaga, Gerard Casaubon, Druso Pérez, Daniela Sara, Pierre-Louis Teissedre, Felipe AvilaModerate red wine consumption has been associated with cardioprotective effects, which have been partly attributed to its polyphenolic content. However, human intervention studies […]I. Urquiaga
- Ultra-processed food consumption and the trajectory of cardio-renal-metabolic multimorbidity: insights from multi-state modelling June 25, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D6FO00970K, PaperShuzhen Zhao, Chengnan Guo, Xin Zhang, Yi Li, Jingkun Hu, Jiayi Huang, Luojia Dai, Zhenqiu Liu, Tiejun ZhangHigher intake of ultra-processed foods is associated with sequential cardio-renal-metabolic multimorbidity, whereas replacing them with unprocessed or minimally processed foods is linked to a lower risk of progressing to severe multimorbidity.To cite […]Shuzhen Zhao
- Unraveling corilagin's absorption and metabolism: a multimodal approach June 25, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO05706J, PaperShi-Dan Wang, Chen-Huan Qiao, Wen-Bo Feng, Tong Liu, Wei Lu, Ding-Hong Wu, Edidiong Uduak Johnson, Yu-Xin ChenCorilagin is an ellagitannin, a natural product found in a wide variety of foods, but its absorption and utilization process in the mammalian intestine is still unclear.To cite this article before page numbers […]Shi-Dan Wang
- Water- and alkali-extracted wheat bran polysaccharides differentially affect antiproliferative and cell death responses in HCT116 and HT29 cells June 25, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D6FO01624C, PaperCandela Paesani, Milena Fronza Broering, Gabriela T. Peréz, João Paulo FabiWheat bran is a major by-product of cereal processing and a rich source of dietary polysaccharides with potential health-promoting properties.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS […]Candela Paesani
- Saturated alginate oligosaccharide as a new functional food: preparation, characterization and alleviation of cognitive impairment through pre-intervention June 25, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D6FO01790H, PaperYoujing Lv, Meng Shao, Zhiliang Fu, Depeng Lv, Qingsen Shang, Yue Yang, Chunlei Wang, Peng Guo, Shuang Lin, Xueyan Zhang, Xia Zhao, Guangli Yu, Quancai LiSAOS ameliorated scopolamine-induced memory deficits in mice and rats by enhancing acetylcholine, alleviating oxidative stress, restoring Roseburia, and reversing reductions in serum N-arachidonoyl dopamine […]Youjing Lv
- Oyster-derived peptide DLAGRDLTDYLM attenuates dexamethasone-induced osteoporosis in rats: associations with lipid metabolism and bone remodeling signatures June 25, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D6FO00926C, PaperWei Yang, Mingtang Tan, Haisheng Lin, Jialong Gao, Zhongqin Chen, Huina Zheng, Xiaoming Qin, Wenhong Cao, Di WuAn oyster-derived peptide, DLAGRDLTDYLM, was screened via a zebrafish model. Its anti-osteoporotic mechanisms in rats were revealed through integrated multi-omics and targeted proteomics.To cite this article before page numbers are assigned, use […]Wei Yang
- Multi-omics integration reveals that pterostilbene ameliorates cyclophosphamide-induced liver injury via the gut-liver axis by inhibiting inflammation and oxidative stress June 24, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D6FO01629D, PaperHuijie Gao, Qi Zhang, Yani Zhu, Yueying Li, Kunzheng Fan, Yuewen Gao, Chao LiuCyclophosphamide (CTX) is a commonly used immunosuppressant and chemotherapeutic drug, yet its clinical application is often restricted by drug-induced liver injury (DILI). Pterostilbene (PTS), a dietary polyphenol abundant in blueberries...The content of this RSS Feed (c) […]Huijie Gao
- Myofibrillar protein-based matrices are associated with altered intestinal lipid handling and enterohepatic signalling in adolescent female mice June 23, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D6FO01317A, PaperMeng Zhou, Mengzhen Ding, Lili Wu, Kun Yang, Hui He, Chunbao LiDietary lipids are typically ingested within complex protein-lipid matrices, where the protein source serves as a primary determinant of lipid digestion and bioavailability. However, the role of myofibrillar proteins, which...The content of this RSS Feed (c) The Royal […]Meng Zhou
- Genetic Variants Modulate Effects of EGCG on Adiposity and Insulinemia in Diversity Outbred Mice June 22, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D6FO00791K, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Dragan Milenkovic, Romit Seth, Michael G. Sweet, Lisard Iglesias Carres, Andrew Peter NeilsonDietary polyphenols have been studied for their potential to mitigate cardiometabolic disease risk; however, their metabolic effects show significant interindividual variability. While […]Dragan Milenkovic
- Dietary 1,3-diacylglycerols rich in γ-linolenic and stearidonic acids improve metabolic parameters and tissue lipid profiles in high-fat diet-induced obese mice June 22, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D6FO01924B, PaperRodrigo Valenzuela, Camila Farias, Yasna Muñoz, Ignacio Alvear, Alejandra Espinoza, Adriano Costa de Camargo, Sandra López-Arana, Miguel Ángel Rincón-CerveraStructured lipids (SLs) enriched in γ-linolenic acid (GLA) and stearidonic acid (SDA) were synthesized as 1,3-diacylglycerols (1,3-DAGs) and evaluated in a high-fat diet (HFD)-induced obesity mouse model. Male C57BL/6J mice...The content […]Rodrigo Valenzuela
- Bound polyphenols from carrot dietary fiber delay aging in Caenorhabditis elegans through the IIS pathway and metabolic remodeling June 22, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D6FO02372J, PaperJinghan Feng, Bing Zheng, Ye Hui, Jianhua Xie, Yi Chen, Xinyi Chen, Xiaobo Hu, Danyang Liu, Ruihong Dong, Qiang YuIn this study, bound polyphenols from carrot dietary fiber, referred to as CDF-BP, were investigated for their anti-aging activity in Caenorhabditis elegans.To cite this article before page numbers are assigned, […]Jinghan Feng
- Association between daidzein metabolism to equol and fecal bile acid profiles in young women June 21, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D6FO01483F, PaperNaho Mizuno-Nagata, Hitoshi Ashida, Toshiya TodaBile acids are a critical factor influencing equol production in humans.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of ChemistryNaho Mizuno-Nagata
- Linkage-dependent effects of procyanidin dimers on TNFα-mediated intestinal epithelial barrier dysfunction, redox homeostasis and inflammation June 21, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D6FO02097F, PaperWei Zhu, Patricia OteizaThe gastrointestinal (GI) tract is generally exposed to high concentrations of dietary components, positioning diet as a key determinant of intestinal inflammation and barrier function, implicated in the onset of...The content of this RSS Feed (c) The Royal Society of ChemistryWei Zhu
- Cinnamaldehyde, a major bioactive component of cinnamon bark, enhances social approach behavior associated with a liver–brain FGF21–isotocin axis in zebrafish June 18, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D6FO00815A, PaperYukiko Nishi, Momoko Kawabe, Seiwa Michihara, Shigeki Chiba, Yuko Kamada-Futagami, Toshiki Hyodo, Akio Inui, Kazuhiro ShiozakiCinnamaldehyde, a major compound in cinnamon bark, enhanced heterospecific social interaction in zebrafish. These effects were associated with increased hepatic Fgf21 expression and activation of brain isotocin- and GABA-related signaling pathways.To cite this article […]Yukiko Nishi
- Outstanding Reviewers for Food & Function in 2025 June 18, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D6FO90046A, EditorialWe would like to take this opportunity to highlight the Outstanding Reviewers for Food & Function in 2025, as selected by the editorial team for their significant contribution to the journal.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this […]
- Efficacy of different dietary fibers for chronic idiopathic constipation: a systematic review and network meta-analysis June 18, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D6FO00286B, Review ArticleJianjiao Mou, Lianlin Zeng, Yangan Li, Meng Sun, Qianlong Li, Kehui Hu, Qiong WangViscous soluble fibers and insoluble fibers rank the highest in efficacy for improving bowel movements in chronic idiopathic constipation, based on a network meta-analysis of multiple fiber types.To cite this article before page numbers are […]Jianjiao Mou
- Traditional fermented camel milk from Xinjiang, China, used as a starter culture exhibits stable fermentation characteristics and anti-colitis effects June 17, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO05107J, PaperFangnuo Deng, Dashuai He, Guangqing Mu, Xinling Li, Yanfeng TuoXinjiang fermented camel milks' microbiota, amino acids, and peptides were characterized. Their fermentation stability and protective effects against colitis were validated, highlighting their functional potential.To cite this article before page numbers are assigned, use the DOI form of citation above.The […]Fangnuo Deng
- Mimicking human milk functions: the human milk oligosaccharide building block GlcNAc in combination with GOS protects the intestinal barrier June 17, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D6FO02196D, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Sonia Kassai, Paul de VosA combination of GlcNAc and GOS has a protective effect on TEER when used to pretreat cells before A23187 exposure.To cite this article before page numbers are assigned, use the […]Sonia Kassai
- Fucoxanthin enhances AMPK/mTOR-dependent autophagic flux and attenuates ferroptosis in Alzheimer's disease models June 17, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D6FO01264G, PaperNayoung Lee, Kumju Youn, Minho Moon, Dong-Seok Lee, Dong Hyun Kim, Chi-Tang Ho, Mira JunFucoxanthin reduced amyloid pathology through autophagy–lysosomal modulation and attenuation of ferroptosis-associated lipid peroxidation.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The […]Nayoung Lee
- Bifidobacterium longum subsp. infantis CCFM1269 alleviates neonatal maternal separation-induced colic in rats by regulating serotonin metabolism, NGF/TrkA signaling pathway and gut microbiota June 26, 2026
