RSC – Food Funct. latest articles- Functional potential of crackers formulated with an innovative fermented cooked chickpea flour March 11, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO05351J, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Manuela Flavia Chiacchio, Silvia Tagliamonte, Giuseppe Blaiotta, Angela Pazzanese, Cristina Juan, Ana Juan-García, Paola VitaglioneIncorporating legume ingredients into staple foods offers a sustainable strategy to promote legume intake while improving the nutritional quality. Fermentation […]Manuela Flavia Chiacchio
- Epigallocatechin-3-gallate ameliorates LPS-induced ARDS by modulating Akkermansia-associated SCFAs metabolism and inhibiting the JAK2/STAT3 candidate signaling pathway March 10, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO05380C, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Shiming Fan, Guofang Yin, Yan Ren, Xiaoqing Fan, Yuling Liang, Ning Ma, Ying Luo, Yi Deng, Chunmei Zhang, Tian Xiang, Jing Zuo, Jingli Tang, Dan Luo, Xianming FanA comprehensive understanding of the mechanisms by […]Shiming Fan
- Bisdemethoxycurcumin extends lifespan and healthspan in Caenorhabditis elegans via modulation of EGFR-linked signaling pathways March 10, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO04963F, PaperRuidie Shi, Yihan Zhang, Chaoxue Li, Xinyue Li, Chuyue Tu, Chen Sun, Shengnan Liu, Ruikun He, Xumei ZhangBDMC targets EGFR, activating Ras/Raf/MAPK while inhibiting PI3K/AKT, leading to extended lifespan, improved stress resistance, and reduced senescence in C. elegans.To cite this article before page numbers are assigned, use the DOI […]Ruidie Shi
- Soybean diacylglycerol oil-based diet impacts lipid levels by altering the gut microbiota in C57BL/6J mice March 9, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO01634G, PaperJia Guo, Manting Du, Yonghua WangUnlike dietary soybean oils, soybean DAG-rich oils may prevent the increased levels of body weight and blood lipids by shaping a healthy host gut ecology and derived metabolites.To cite this article before page numbers are assigned, use the DOI form of citation above.The content […]Jia Guo
- Beyond A1 milk concerns: dietary-relevant concentrations of β-casomorphin-7 show limited absorption but retain opioid-like activity in an intestinal cell model March 9, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO04465K, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Giorgia Antonelli, Giovanni Piccinini, Mattia Santoni, Terenzio Bertuzzi, Davide Risso, Federico Canzoneri, Roberto Menta, Nicole Tosi, Liliana Milani, Cristian Del Bo’, Alessandra Bordoni, Margherita Dall'Asta, Francesca Danesiβ-Casomorphin-7 (BCM-7) exhibits local opioid activity in intestinal […]Giorgia Antonelli
- Probiotic cell wall components as emerging postbiotics: Structural diversity, immunoregulatory mechanisms, and health applications March 9, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D6FO00491A, Review ArticleLina Ding, Jiaqi Yin, Jiaqi Liu, Jing Zou, Junwen Liu, Yao Jin, Maolin Tu, Ping Li, Qing Gu, Jia-run HanProbiotics exert health benefits through multifaceted interactions with the host, and accumulating evidence indicates that many of these effects are mediated by defined cell envelope-derived molecules rather than live […]Lina Ding
- Systematic evaluation of permeability-related behavior and physicochemical determinants of structurally diverse phytochemicals using a Caco-2 cell model March 9, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO05099E, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Rixing Cong, Jin-Woo Kim, Jun-Su Park, Jin-Soo Park, Kyungsu Kang, Soon-Mi ShimUnderstanding the intestinal permeability of phytochemicals is essential for elucidating their bioavailability and physiological efficacy.To cite this article before page numbers are assigned, […]Rixing Cong
- Dietary EPA shows superior efficacy over DHA in chronic sleep deprivation-induced cognitive decline by disrupting the crosstalk between intestinal ferroptosis and gut-derived Aβ production March 9, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO03915K, PaperLu Chen, Xue Wang, Yueqi Yang, Haohao Shi, Ning Zhang, Zhengping Wang, Jun Han, Min WenDietary eicosapentaenoic acid (EPA) mitigates the cognitive decline from chronic sleep deprivation via multi-target regulation of the gut–brain cerebral β-amyloid axis showing EPA-enriched functional foods could be used to manage sleep disturbance.To cite this […]Lu Chen
- Regular Black Tea Kombucha Consumption is Associated with Improved Insulin Resistance and Increased ADIPOQ Expression in Adults with Obesity: A Pre-Post Clinical Trial March 7, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO02226F, PaperMirian Aparecida de Campos Costa, Gabriela Macedo Fraiz, Rodrigo Cardoso, Alessandra Silva, Vinícius da Silva Duarte, Carlos Eduardo Soares Gazzinelli Cruz, Evando Geraldo Rodrigues, Maliha Shaikh, Ali Keshavarzian, Bruce R. Hamaker, Viviana Corich, Alessio Giacomini, Hercia Stampini Duarte Martino, Josefina Bressan, Frederico BarrosKombucha is a fermented beverage obtained by […]Mirian Aparecida de Campos Costa
- Bifidobacterium breve CCFM1078 alleviates DNFB-induced atopic dermatitis in early-life via AhR activation, Th1/Th2 immune modulation, and gut microbiota regulation March 6, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO05688H, PaperYongqi Li, Huizhen Li, Qing Zhang, Shumao Cui, Qixiao Zhai, Catherine Stanton, Paul Ross, Jianxin Zhao, Wei Chen, Bo YangEarly-life B. breve CCFM1078 alleviates DNFB-induced AD via gut-skin axis: remodels gut microbiota, elevates colonic IgA/sIgA; activates skin AhR pathway and inhibits TSLP; restores Th1/Th2 balance and reduces mast cell infiltration.To cite this article […]Yongqi Li
- Sea cucumber peptides alleviate hyperuricemic nephropathy via HIF-1α/NF-κB/STAT3-SIRT1/p300 axis-mediated metabolic and epigenetic modulation March 6, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO05202E, PaperPeiting Lv, Xinran Liu, Ximing Yang, Xue Sang, Lushun Yuan, Shuzhen Cheng, Ming DuSea cucumber peptides modulate uric acid, metabolism, and epigenetics through multiple mechanisms to improve hyperuricemic kidney injury.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS […]Peiting Lv
- Folic acid protects endothelial cells dysfunction against T2DM-induced ferroptosis by activating the SIRT6/NRF2/GPX4 signaling pathway March 6, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO04381F, Paper Lei Hong, Xinqi Lou, Yingjie Zha, Xuejie Fu, Tuanjie Che, Shigang Qiao, Chen Wang, Jianzhong AnCardiovascular complications associated with type 2 diabetes mellitus (T2DM) pose a serious threat to human health. Folic acid deficiency is associated with various diseases, including atherosclerosis. However, it remains unclear...The content of this […]Lei Hong
- Dietary iron supplementation modulates thyroid immune homeostasis and ameliorates experimental autoimmune thyroiditis in mice March 6, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO05210F, PaperYing-Jie Chen, Chun-Mei Wang, Qi-Lan Jiang, Tao Li, Jun JiangDietary iron supplementation prevents autoimmune thyroiditis through immunoregulation, promoting Treg/B10 cells while suppressing Th1/Th17/Tfh. These findings support iron optimization as a prevention strategy.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of […]Ying-Jie Chen
- The effect of vitamin C supplementation on blood pressure in adults: an umbrella review of meta-analyses of randomized clinical trials March 5, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO03679H, Review ArticleAli Kosari, Hossein Shahinfar, Kimia Rostampour, Seyedeh Ghazal Mirhosseini, Sepideh SoltaniVitamin C supplementation significantly reduces systolic blood pressure (−4.14 mmHg) with modest diastolic reduction, particularly benefiting patients on antihypertensive medication.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this […]Ali Kosari
- Diacylglycerol Ameliorates Obesity-Induced Osteoporosis through inhibiting NF-κB pathway Mediated Osteoclast Differentiation March 4, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO05472A, PaperHao Yue, Xiuxiu Wang, ya liu, Min Jia, Aizhen Zong, Fangling Du, Tongcheng XuWith the rapid increase in obesity rates, osteoporosis caused by obesity has become a serious social health problem. Diacylglycerol (DAG) is a structural lipid with multiple metabolism benefits. However, the...The content of this RSS Feed (c) […]Hao Yue
- Association between Mushroom Consumption and Digit Span Performance among Middle-aged and Older Community-dwelling Japanese: The NILS-LSA Project March 4, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO04625D, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Shu Zhang, Djibril M. Ba, Yukiko Nishita, Chikako Tange, Junjia Zhu, Rei Otsuka, Joshua MuscatCognitive decline, particularly in short-term and working memory, is a major concern in aging populations. Mushrooms contain bioactive compounds that […]Shu Zhang
- Association of dietary choline and betaine intake with diabetes risk: a prospective cohort study from the China Health and Nutrition Survey March 3, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO02252E, PaperShangling Wu, Peiyan Chen, Yi Sui, Peishan Tan, Jialin Lu, Wenting Wang, Wei Lu, Aiping FangModerate dietary choline intake may help prevent diabetes, particularly in Chinese populations with predominantly plant-based diets.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this […]Shangling Wu
- The Potential of Natural Dietary Products in Mitigating Inflammation during Pregnancy March 3, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO05195A, Review ArticleJanice Garcia-Quiroz, Abigail García-Morales, Euclides Avila, Consuelo Lomas-Soria, Andrea Olmos-Ortiz, Lorenza DíazExacerbated inflammation in pregnancy can be detrimental in many aspects, and can result in spontaneous abortion, intrauterine growth restriction, or preterm delivery. The inflammatory cascade may be triggered by pathogen...The content of this RSS Feed (c) The […]Janice Garcia-Quiroz
- Companilactobacillus alimentarius CNTA 209 alleviates diet-induced obesity in mice through adipose tissue browning and gut barrier modulation March 3, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO04242A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Lorena Valdés-Varela, Ignacio Goyache, Raquel Virto, Neira Sáinz, Miguel López-Yoldi, Ana Sánchez-Vicente, Noelia López-Giral, Ana Gloria Gil, Fermín I. Milagro, Paula AranazThe use of probiotics with health-promoting effects has emerged as a promising therapeutic […]Lorena Valdés-Varela
- Can dairy beverages promote post-exercise recovery in young female athletes? A crossover study on milk and kefir March 3, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO05127D, PaperMarco Pernigoni, Leonardo Cesanelli, Elena Cesanelli, Rima Bakienė, Valeria Polzonetti, Inga LukonaitienėThis study assessed the effect of milk and kefir on post-exercise recovery in young female athletes.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The […]Marco Pernigoni
- Functional potential of crackers formulated with an innovative fermented cooked chickpea flour March 11, 2026
