RSC – Food Funct. latest articles- Integrating population-based metabolomics with computational microbiome modelling identifies methanol as a urinary biomarker for protective diet-microbiome-host interactions August 4, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO00761E, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Kristin Klier, Ameneh Mehrjerd, Daniel Fässler, Maximilien Franck, Antoine Weihs, Kathrin Budde, Martin Bahls, Fabian Frost, Ann-Kristin Henning, Almut Heinken, Henry Völzke, Marcus Dörr, Matthias Nauck, Hans Jörgen Grabe, Nele Friedrich, Johannes HertelBackground: Diet-microbiome […]Kristin Klier
- Dietary hispidulin ameliorated chemically-Induced colitis by inhibiting epithelial cell ferroptosis via the ACAT2-GPX4 axis and remodeling the gut microbiota August 4, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO02648B, PaperDapeng Chen, Jiayi Li, Xinyu Li, Kexin Zhang, Shujie Zeng, Shenjun Zhang, Longyun Li, Yongjian XiongHispidulin, a dietary flavonoid occurring naturally in brown algae, has attracted considerable interest owing to its functions in modulating inflammatory responses and neutralizing reactive oxygen species. This study examined the...The content of this RSS […]Dapeng Chen
- Urate-lowering and renal-protective effects of sugarcane polyphenols in hyperuricemia: mechanisms and key components August 4, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO00508F, PaperKexin Li, Yu Han, Yumei Wang, Chengfeng Zhang, Wanlu Liu, Yu Xi, Yanv Zhou, Lu Li, He LiSugarcane polyphenols, lower uric acid levels in hyperuricemia by reducing its hepatic production and promoting renal excretion, primarily through chlorogenic acid, while also providing renal protection by inhibiting inflammatory pathways.To cite this […]Kexin Li
- Adherence to the EAT-Lancet reference diet and risk of type 2 diabetes, metabolic dysfunction-associated steatotic liver disease, and their co-occurrence August 4, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D4FO05852F, PaperShunming Zhang, Xu-Fen Zeng, Yan Borné, Zhenyu Huo, Yan Yan, Yeqing Gu, Hongmei Wu, Xiaoqin Luo, Rui Zhang, Anna Stubbendorff, E. Sonestedt, Lu Qi, Tao Huang, Ming-Hua Zheng, Kaijun Niu, Le MaBackground and aims: The EAT-Lancet Commission proposed a healthy dietary pattern to prevent diet-related diseases while promoting planetary […]Shunming Zhang
- Lactiplantibacillus plantarum MPB-65 combined with epicatechin alleviates hyperuricemia by modulating the gut–kidney axis August 3, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO01265A, PaperZihao Tian, Jing Zhang, Zhongmei Tan, Xiaolei Duan, He Zhang, Bailiang Li, Enyu Wang, Vicky Yang Wang, Dong Xu, Jiage Ma, Wei YuLactiplantibacillus plantarum MPB-65 combined with epicatechin alleviates hyperuricemia by inhibiting xanthine oxidase activity, modulating the expressions of uric acid transporters, regulating gut microbiota dysregulation and enhancing SCFAs […]Zihao Tian
- Effects of ‘Mapo’ tangelo (Citrus x tangelo) extracts, essential oil, and isolated compounds on LDL receptor and PCSK9 expression in human hepatocarcinoma cell line Huh7 July 31, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO01511A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Irene Ferrarese, Maria Giovanna Lupo, Ilaria Rossi, Giorgia Marodin, Haixia Chen, Stefania Sut, Nicola Ferri, Stefano Dall'AcquaPeel (MPLE), pulp extract (MPPE) and the essential oil (MPO) of Citrus x tangelo were studied for their […]Irene Ferrarese
- Weissella confusa WIKIM51 (Wilac D001) improves constipation and gut health in a loperamide-induced mouse model July 30, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO02365C, PaperDan-Bi Ki, Jong-Yeon Kim, Varun Jaiswal, Byung Wook Lee, Sang Min Park, Eun-Jung Park, Hae-Jeung LeeWeissella confusa WIKIM51 (Wilac D001) has been reported to reduce body fat, but its potential effects on constipation remain unclear. This study is the first to demonstrate that Wilac D001...The content of this RSS […]Dan-Bi Ki
- Dictyophora indusiata polysaccharide fractions promote the proliferation and metabolism of Bifidobacterium longum F2 July 30, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO02732B, PaperLin Wang, Yaqing Lin, Zhikun Zeng, Zihao Zhang, Baodong Zheng, Lei Pan, Yi ZhangDictyophora indusiata polysaccharide fractions remained structural stability during in vitro digestion and promoted the proliferation and metabolism of Bifidobacterium longum F2.To cite this article before page numbers are assigned, use the DOI form of citation above.The […]Lin Wang
- Lactic acid bacteria and staphylococci improve swallowability of fermented meat pastes by modulating texture and flavor July 30, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO02066B, PaperAn He, Yufeng Zou, Jiaming Cai, Yuan Li, Yuting Wang, Dengyong LiuThis study aims to enhance the swallowing characteristics of fermented meat pastes by improving their texture and flavor through the targeted inoculation of different starter cultures.To cite this article before page numbers are assigned, use the DOI form […]An He
- Grape Pomace Extract, Rich in Phenolic Compounds, Attenuates Obesity-Induced Nephropathy by Modulating Energy Metabolism Dysregulation and Oxidative Stress in Mice Fed a High-Fat Diet. July 29, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO02327K, PaperTatiana Figueras, Diahann Jeanette Perdicaro, Valeria E. Cacciamani, Andrea F. Gil Lorenzo, Laila Suhaiman, Andrea Antoniolli, Marcela Alejandra Vazquez Prieto, Valeria Victoria CostantinoObesity constitutes a significant risk factor for chronic kidney disease. High-fat diets (HFD) disrupt glucose and lipid metabolism and promote ectopic lipid deposition, leading to renal lipotoxicity […]Tatiana Figueras
- Clostridium butyricum JJ100 and Lacticaseibacillus rhamnosus LR alleviate liver injury in mice caused by continuous high-dose-alcohol exposure by protecting the intestinal barrier, rebuilding the gut microbiota and regulating AMPK and TLR4/NF-κB signaling pathways July 29, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO00915D, PaperYonghao Hu, Yujie Wang, Xudong Li, Qiong Xie, Zhitang LyuAlcohol consumption poses a major global public health challenge, with excessive drinkers showing heightened susceptibility to alcoholic liver disease (ALD) – a condition with complex pathogenesis.To cite this article before page numbers are assigned, use the DOI form of citation […]Yonghao Hu
- Design, synthesis and evaluation of gluten peptide analogues as inhibitors of the HLA/DQ8-mediated celiac immune response July 28, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO01270H, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Lucia Treppiccione, Vincenzo Mangini, Annarita Del Gatto, Daniela Trisciuzzi, Francesco Maurano, Anna Giovanna Sciancalepore, Laura Zaccaro, Benny Danilo Belviso, Orazio Nicolotti, Michele Saviano, Mauro Rossi, Rocco CaliandroThe immune response induced by gluten is the […]Lucia Treppiccione
- Gut microbiota mediated the curvilinear associations between dietary animal protein intake and bone mineral density in Chinese adults July 28, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO01417D, PaperYanjun Deng, Qiong Zhang, Maoxin Ren, yun Zhang, Guang Li, Hao Feng, Xiaobao Wang, Yuhao Cui, Jiamei Huang, Xinliang Mao, Sumei XiaoDietary protein intake is closely related to bone health. It remains unclear how different dietary protein sources contribute to bone mass and how the gut microbiota affects these […]Yanjun Deng
- The therapeutic potential of pomegranate in the prevention and management of noncommunicable diseases July 28, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO01999K, Review ArticleAsad Ur Rahman, Muhammad Esa, Pharkphoom PanichayupakaranantNoncommunicable diseases (NCDs), including cardiovascular diseases, cancer, respiratory conditions, and metabolic and central nervous system disorders, are the leading causes of morbidity and mortality worldwide.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of […]Asad Ur Rahman
- A standardised saffron extract improves subjective and objective sleep quality in healthy older adults with sleep complaints: results from the gut-sleep-brain axis randomised, double-blind, placebo-controlled pilot study July 28, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO00917K, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Leonie Lang, Annabel Ditton, Andi Stanescu, Vernisse Jainani, Simon McArthur, Line Pourtau, David Gaudout, Matthew G. Pontifex, Jordan Tsigarides, Taylor Steward, Saber Sami, Michael Muller, Michael Hornberger, David Vauzour, Alpar S. LazarSleep disturbances are […]Leonie Lang
- Dietary protein from different sources escapes host digestion and is differentially modified by gut microbiota July 28, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO01132A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Ayesha Awan, Alexandria Bartlett, J. Alfredo Blakeley-Ruiz, Tanner Richie, Casey M. Theriot, Manuel KleinerProtein is an essential macronutrient and variations in its source and quantity have been shown to impact long-term health outcomes. Differential […]Ayesha Awan
- Natural polyphenol rutin inhibits ferroptosis in ulcerative colitis by regulating lipid metabolism via blocking the LCN2-ALOX15 axis July 28, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO01220A, PaperYiming Sun, Guixuan Fang, Kangdi Liu, Yulu Zhao, Zhujie Bai, Tanxuan Huang, Honghui Hu, Nan Zhou, Jiali Peng, Lianxiang LuoUlcerative colitis (UC), a chronic inflammatory disorder with elevated carcinogenic risk, urgently requires multi-target therapeutic strategies. Ferroptosis, characterized by iron-dependent lipid peroxidation, emerges as a promising intervention target for intestinal...The […]Yiming Sun
- Theabrownins from dark tea: formation, gut microbiota-mediated biotransformation, health benefits, and potential in functional food applications July 27, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO02046H, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Chunyan Zhang, Mingxi Li, Liya Li, Chunpeng Wan, Yaodong Xia, Hang Ma, Jialin XuTheabrownins (TBs) are the major polyphenol-derived pigments and key bioactive components in dark tea formed through microbial fermentation and/or enzymatic […]Chunyan Zhang
- The effect of the biofilm-forming Lactiplantibacillus plantarum F3-2 on improving lipid accumulation in vitro July 24, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO02121A, PaperJidan Yu, Na An, Lanwei Zhang, Zhi Duan, Jiadong LiObesity correlates with gut microbiota dysbiosis, with beneficial microbial intervention emerging as a promising therapeutic strategy for obesity-associated metabolic disorders.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed […]Jidan Yu
- Enhanced bound antioxidant capacity of oat bran treated with green tea infusion modulates antioxidant release and short chain fatty acid formation during colonic fermentation July 24, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO01281C, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Ezgi Doğan Cömert, Vural Gökmen, Edoardo CapuanoThe enhanced bound antioxidant capacity of oat bran by green tea benefits colon health by enabling a slower and greater release of antioxidants, as well as promoting short-chain […]Ezgi Doğan Cömert
- Integrating population-based metabolomics with computational microbiome modelling identifies methanol as a urinary biomarker for protective diet-microbiome-host interactions August 4, 2025
