RSC – Food Funct. latest articles- Rhodomyrtus tomentosa fruit alleviates hippocampal neuroinflammation, apoptosis, and rescues neurogenesis to ameliorate depressive-like behaviors in CUMS-challenged mice January 20, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO04575D, PaperYun-Tao Zhao, Jingxi Zhang, Jinyuan Liang, Yan Xu, Jingyu Sun, Mengyue Zhang, Zhi-You Yang, Leigang Jin, Shaohong Chen, Chuanyin HuRhodomyrtus tomentosa fruit is an edible berry with diverse bioactivities. However, its antidepressant effects remains unexplored. The purpose of this study was to evaluate the impact of Rhodomyrtus tomentosa fruit...The […]Yun-Tao Zhao
- Next-Generation Liposomal Coenzyme Q 10 : From Formulation to Clinical Evidence via Metazome Technology for Improved Stability and Enhanced Oral Absorption January 20, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO05217C, PaperAugustine Amalraj, Eldo K Abraham, Ann Mariya Jogy, Sreeraj GopiCoenzyme Q 10 (CoQ 10 ) is a mitochondrial cofactor and antioxidant used in cardiovascular, neurodegenerative, and metabolic disorders, but its clinical efficacy is limited by poor solubility, crystallinity, and...The content of this RSS Feed (c) The Royal Society of […]Augustine Amalraj
- The therapeutic mechanism of borneol acetate in alleviating ulcerative colitis by regulating the intestinal flora January 15, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO05003K, PaperBingqing Shang, minghui Yang, Liduan Yin, Suyuan Lv, Tong Wang, Qiu Wu, Yue GengUlcerative colitis (UC) is a chronic and relapsing inflammatory bowel disease with an increasing global burden. Although various terpenoids have demonstrated significant efficacy against UC, the therapeutic mechanism of bornyl...The content of this RSS Feed (c) […]Bingqing Shang
- Correction: Improvement effect of a next-generation probiotic L. plantarum-pMG36e-GLP-1 on type 2 diabetes mellitus via the gut–pancreas–liver axis January 14, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D6FO90005D, Correction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Hong Hu, Jie Luo, Ying Liu, Hongyu Li, Rui Jin, Shengjie Li, Jing Wei, Hong Wei, Tingtao ChenTo cite this article before page numbers are assigned, use the DOI form of citation above.The content […]Hong Hu
- Impact of anthocyanin-rich black rice consumption on cognitive function, inflammation and microvascular function in older adults: a crossover intervention trial January 13, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO04351D, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Chusana Mekhora, Daniel J. Lamport, Jeremy P. E. SpencerThe consumption of anthocyanin-rich black rice enhanced verbal memory and decreased blood IL-6 levels in older adults.To cite this article before page numbers are assigned, use […]Chusana Mekhora
- NAFLD-related SNPs are linked to changes in liver fat, measured by CAP score, and serum lipids in response to a 3-week sugar sweetened beverage intervention: A pilot study January 13, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO03248B, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Faustina Therase Jeyaraj, Sai Sravani Vennam, Kendra L Nelson, Katherine Watts, Lydia R Goss, Brea C Nance, Baba B Mass, Venkata Saroja VorugantiStudies show that increased consumption of sugar sweetened beverage (SSB) is linked […]Faustina Therase Jeyaraj
- Sulfated polysaccharides from sea cucumber mitigate acetaminophen-induced acute liver injury in mice via citraconic acid-mediated inhibition of oxidative stress January 13, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO04767F, PaperJiacheng Cheng, Weiyun Zheng, Jiayi Yan, Shuang Song, Chunqing AiSea cucumber sulfated polysaccharides alleviate acetaminophen - induced liver injury by modulating gut microbiota to elevate citraconic acid, which activates hepatic Nrf2 to reduce oxidative stress, as validated in vivo and in t-BHP-treated cells.To cite this article before page numbers […]Jiacheng Cheng
- Proteins and lunasin from Glycine soja inhibited inflammation by activating the Hippo pathway through phosphorylation of YAP1 kinase January 13, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO02971F, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jennifer Kusumah, Jiazheng Yuan, Elvira Gonzalez de MejiaThe Hippo pathway has attracted scientific interest as a target for anti-inflammation and anti-cancer therapy. Our objective was to elucidate and compare the potential anti-inflammatory mechanism of […]Jennifer Kusumah
- Rutin alleviates dietary advanced glycation end products (AGEs)-induced insulin resistance in mice by modulation of gut microbiota January 13, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO04604A, PaperYi Lu, Lijun Chang, Shuangbo Liu, Mingfu Wang, Yueliang ZhaoDietary advanced glycation end products (AGEs), formed during thermal food processing, are associated with metabolic disorders.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society […]Yi Lu
- Effects of jabuticaba, a Brazilian berry, on obesity, metabolic parameters, and gut health in high-fat diet animal models: a systematic review January 13, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO03883A, Review ArticleLívya Alves Oliveira, Kelly Aparecida Dias, Stephanie Michelin Santana Pereira, Lívia Carvalho Sette Abrantes, Stefany da Silva Paes, Thaís Cupertino Fialho, Ceres Mattos Della LuciaJabuticaba intake reduced weight gain, inflammation, oxidative stress, hepatic steatosis, and improved insulin sensitivity, glucose tolerance, and gut health through modulation of the intestinal […]Lívya Alves Oliveira
- Cocoa flavanols protect endothelial function during prolonged sitting in healthy older adults January 13, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO02793D, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Alessio Daniele, Samuel J. E. Lucas, Catarina RendeiroTwo hours of sitting impaired upper and lower limb endothelial function (flow-mediated dilation; FMD) and increased blood pressure in healthy older adults. Consuming flavanols prior to sitting […]Alessio Daniele
- Association of breast milk betaine and related metabolites with neurodevelopment in 6-month-old infants: A prospective birth cohort study January 12, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO04631A, PaperQiaoli Huang, Fengfeng Guo, Haoyan Zou, Yufang Zhang, Beibei Xu, Jie Li, Yu Xiao, Siyao Zhou, Mingzhe Kou, Hexin Lin, Shanxing Gong, Xuying Tan, Fengxiang Wei, Lijun WangBackground&Aims: Currently, there is a paucity of systematic research investigating the associations between betaine and its related metabolites in breast milk and […]Qiaoli Huang
- Chlorogenic acid alleviates chronic restraint stress-induced liver injury potentially via Nrf2-mediated inhibition of ferroptosis and mitochondrial apoptosis January 12, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO04627K, PaperHaoyang Tan, Yaxin Ji, Xin Cheng, Jiahuan Hu, Xiaoqing Yu, Jiaxing Wang, Haotian Yang, Shuai Zhang, Guofeng Feng, Wenjing Jiao, Yuan Zhao, Honggang FanChlorogenic acid alleviates chronic restraint stress–induced liver injury by improving iron metabolism and reducing oxidative stress, potentially through Nrf2-mediated inhibition of ferroptosis and mitochondrial apoptosis.To cite […]Haoyang Tan
- Effect of maqui berry extract consumption on postprandial responses in mice: actions on digestive enzymes and relevance of DPP-IV inhibition January 12, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO04669F, PaperAgustin Lucini Mas, Juana I. Mosele, Carmen Carrieri, Claudia Favari, Letizia Bresciani, Pedro Mena, Cesar Fraga, Monica GalleanoObesity remains a major global public health concern. Existent strategies to cope with obesity include inhibiting key digestive enzymes. This study evaluated the inhibitory potential of a maqui berry extract...The content of […]Agustin Lucini Mas
- Multi-omics reveals gut microbiota-derived taurodeoxycholic acid mediates the protective effect of Lactobacillus rhamnosus GG against LPS-induced liver injury January 12, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO05530J, PaperPeng Wang, Yupu Wang, Wenting Gao, Menghao Wang, Yangming Liu, Lin Feng, Haoran Yin, Mengran Chen, Linlin zhai, Peiqiang Yuan, Hanzhen Qiao, Liping Gan, Jinrong WangGut microbiota-derived lipopolysaccharide (LPS) is a critical mediator in the pathogenesis of nonalcoholic fatty liver disease and metabolic syndrome. The liver plays a crucial […]Peng Wang
- Sulforaphane attenuates DSS-induced ulcerative colitis via the Nrf2/STAT3 signaling pathway and gut microbiota modulation January 9, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO04156B, PaperMengyuan Chen, Gejun Yu, Wentao Wu, Peng Lei, Xiaohong Zhang, Jingyi Ren, Xiaoxin Jiang, Mengjie Yang, Canxia HeMechanism by which SFN alleviates DSS-induced colitis in Caco-2 cells and a mouse model.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this […]Mengyuan Chen
- Protective effect of Rosemarinus officinalis and its nanoparticles against chemobrain and neuroinflammation in rats: Involvement of Wnt/β-Catenin signaling and apoptotic machineries January 9, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO04462F, PaperMina Youssif, Iriny Ayoub, Nadine C Sabry, Nesma Khaled, Maha Nasr, Fadia S. YoussefChemobrain, constitutes a major debilitating effect experienced by cancer patients receiving chemotherapy as oxaliplatin that induces chemofog and neuroinflammation. This study aimed to evaluate the protective effect of the ethanol...The content of this RSS Feed (c) […]Mina Youssif
- Chlorogenic acid improves DSS-induced colitis in mice by regulating gut microbiota January 9, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO02858B, PaperQinqiu Zhang, Shixiong Deng, Yiya Sun, Jiajun Lv, Danka Bukvicki, Yaowen Liu, Qing Zhang, Derong Lin, wen QinChlorogenic acid (CGA) is a polyphenol widely found in plants with a wide range of biological activities, especially anti-inflammatory. The connection that CGA improves colitis by regulating gut microbiota has...The content of […]Qinqiu Zhang
- Polysaccharides from Edible Fungi Mycelium: A Review on Extraction, Characterization, Bioactivities, and Biosynthetic Mechanisms January 9, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO04747A, Review ArticleLixiang Zheng, mengge Ma, Zhou Chen, SiTing Li, Yingmin JiaPolysaccharides derived from the mycelium of edible fungi (MEF) are structurally diverse and biologically active macromolecules garnering extensive attention in functional foods, pharmaceuticals, and biomaterials. Despite the emerging growth in...The content of this RSS Feed (c) The Royal Society […]Lixiang Zheng
- Early-life gut microbial reconstitution with Lactobacillus johnsonii during lactation mitigates high-fat diet-induced obesity in adult mice January 8, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO04887G, PaperZhongxin Li, Zhifei Wang, Qiang Huang, Zhuqing Xie, Bin ZhangEpidemiological and animal studies have suggested that early-life overfeeding (ELOF) triggers lasting metabolic dysfunction. However, the role of gut microbiota in this process remains largely unelucidated. Here, we established a...The content of this RSS Feed (c) The Royal Society of […]Zhongxin Li
- Rhodomyrtus tomentosa fruit alleviates hippocampal neuroinflammation, apoptosis, and rescues neurogenesis to ameliorate depressive-like behaviors in CUMS-challenged mice January 20, 2026
