RSC – Food Funct. latest articles- Synergy of Secoisolariciresinol diglucoside and fructooligosaccharide on enhancement of intestinal mucus barrier based on relieving ER stress and regulating gut microbiome July 10, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO01526J, PaperLi Zhang, Muhua Ji, Ning Li, Jingjing Yu, Guiming Yan, Yan Di, Yuchun Zhang, Qian Liu, Lijun Sun, Xuebo Liu, Yutang WangImpairment of the intestinal barrier and high incidence of gastrointestinal diseases can be caused by poor dietary patterns such as long-term high-fat diets. The mucous layer, which is […]Li Zhang
- An innovative functional fermented vegetable milk analogue, fermented by Acidipropionibacterium acidipropionici, Lactobacillus delbrueckii and Lactococcus lactis, mitigates the inflammatory response in vitro and in vivo. July 10, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO01061F, PaperNassima Illikoud, Christel Rousseaux, Céline Even, Barbara Misme-Aucouturier, Grégory Bouchaud, Marine Mantel, Malvyne Rolli-Derkinderen, Valérie Gagnaire, Gwenael JanIndustrialised developed western countries experience a seek for alternative sources of proteins, sustained by a demand for healthier food, with enhanced respect of animal welfare. Concomitantly, these countries are subjected...The content of […]Nassima Illikoud
- Aloe vera polysaccharides mitigate high-fat high-cholesterol diet-induced atherosclerosis in ApoE-/- mice via regulation of lipid metabolism and gut microbiota July 10, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO01995H, PaperShenji Yang , Xiaojun Huang , Xiajialong Li, Jing Feng , Peng Chen, Zhikang Cao , Luyao He, Chaojun Li, Zhipeng Li, Ming-Yong XieCardiovascular diseases are leading causes of death globally, often manifesting after years of atherosclerosis (AS) progression. In this study, we investigated the atheroprotective effects of three […]Shenji Yang
- Dietary total, animal, and plant protein-energy ratio and risk of mortality: results from the NHANES III and an all life-long animal experiment July 10, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D4FO05785F, PaperZican Li, Lianjie Huang, Qiushuang Zhu, Fanyun Wang, Defang Li, Bo Qu, Runan Zhang, Yue Guan, Akinkunmi Paul Okekunle, Jiaying Yu, Yuqing Wu, xuanfeng tang, Xiaoqing Li, Xinyi Lv, Xiang Shu, Xiangju Kong, Rennan FengBackground: Protein is essential for basic physiological functions of the body, but the relationship between […]Zican Li
- Exploring Galician phenolic-rich olive oil as a glycemic control strategy: The OILDIABET randomized trial July 10, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO00873E, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.María Figueiredo-González, Inés Seoane-Cruz, Patricia Reboredo-Rodríguez, Eva Fernández-Rodríguez, Manuel Marcos-García, María José Menor-Rodríguez, Beatriz Calderón-Cruz, Carmen González Barreiro, José Antonio Mato-Mato, Beatriz Cancho-GrandeThe rising prevalence of type 2 diabetes (T2D) demands effective dietary strategies. […]María Figueiredo-González
- Vitamin K2 reprograms the multi-organ transcriptional landscape in mice with high-fat diet-induced obesity July 9, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO01613D, PaperXuanyang Wang, Yuntao Zhang, Lin Liu, Hongkun Ma, Chunbo Wei, Xiaoqing Xu, Jia Zhang, Sijia Pan, Yingfeng Zhang, Jiepeng Chen, Lili Duan, Guannan Geng, Keke Dang, Hongquan Xie, Guoliang Wang, Lin Li, Ran Li, Ying LiVitamin K2 (VK2) significantly rescues the multi-organ transcriptome and restores tissue-specific pathways in high-fat […]Xuanyang Wang
- Molecular mechanisms of aberrant fatty acids metabolism in driving cardiovascular diseases: key regulatory targets and dietary interventions July 9, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO01237F, Review ArticleRui Yang, Jiao Pang, Xue Zhong, Shuyang Pang, Xuefeng Hu, Chenfei Wei, Weiqi Yan, Xueting Chen, Rui Zhao, Baojun Xu, Zhipeng CaoAberrant fatty acid metabolism promotes cardiovascular disease via oxidative stress, inflammation, and vascular dysfunction. Targeting key pathways and optimizing lipid intake offers promising strategies for prevention and […]Rui Yang
- Insight into the underlying mechanism of functional Pediococcus acidilactici SWU-HX39 in alleviating hyperuricemia July 9, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO01404B, PaperJuxin He, Xirui Zhang, Huijing Chen, Jianquan Kan, Sameh Awad, Amel Ahmed Ibrahim, Zsolt Zalán, Muying DuHyperuricemia (HUA) is a major challenge in the field of public health, and long-term use of traditional drugs can easily lead to addiction and some side effects such as hypersensitivity...The content of this […]Juxin He
- Weizmannia coagulans BC99 alleviates hyperuricemia by restoring liver–kidney–gut axis dysfunction caused by hyperuricemia July 7, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO00951K, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Ying Wu, Yinyin Gao, Cheng Li, Shirui Zhai, Yao Dong, Shanshan Tie, Lina Zhao, Shaobin GuBC99 reduces serum uric acid and inhibits UA synthesis in hyperuricemic mice by down-regulating reabsorption proteins, URAT1/GLUT9 and up-regulating […]Ying Wu
- Non-pungent capsiate enhances longevity and healthspan in Caenorhabditis elegans via transient receptor potential (TRP) channels July 7, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO01607J, PaperNathan Lyttle, Mohankumar Amirthalingam, Julia Bali, Alan Yazid Chavez Hita Wong, Juan Gerardo Flores Iga, Shinkichi Tawata, Padma Nimmakayala, Umesh K. ReddyCapsiate, a non-pungent capsaicin analog, promotes stress resilience and longevity in C. elegans via TRP channel-dependent activation of DAF-16/FoxO and SKN-1/Nrf2, offering mechanistic insights into its pro-longevity effects.To […]Nathan Lyttle
- A dietary switch from a high fat to a low fat diet mitigates obesity-induced intestinal barrier dysfunction in mice: Implications for pancreatic carcinogenesis July 6, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO02372F, PaperJazmin Machuca, Joanna Wirkus, Aya S. Ead, Crystal Y Cheon, Gerardo Guillermo Mackenzie, Patricia OteizaConsumption of high-fat diets (HFD) is linked to increased intestinal permeability and metabolic endotoxemia, which may contribute to pancreatic cancer development. We previously showed that 8-week HFD consumption altered intestinal...The content of this RSS Feed […]Jazmin Machuca
- Development of a bio-functional fermented soy beverage supplemented with microbial exopolysaccharides and its effect on the human gut microbiome in vitro July 3, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO01288K, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Giulia Bisson, Clara Comuzzi, Jamie A FitzGerald, Arghya Mukherjee, Niccolò Renoldi, Nadia Innocente, Tom Beresford, Harsh Mathur, Paul D. Cotter, Marilena MarinoThe gut microbiome plays a key role in modulating human health and well-being. […]Giulia Bisson
- Co-administration of curcumin forms with supplemental iron: a study of effects on iron absorption and intestinal cellular health July 3, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO00658A, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Marta M. Gámez-Fernández, Helena Tiekou Lorinczova, Stefanie Ho Yi Chan, Satyanarayana Somavarapu, Vinood B. Patel, Sanjoy K. Deb, Mohammed Gulrez ZariwalaIron supplementation often causes gastrointestinal distress. Co-administration with formulated curcumin may help protect gastrointestinal […]Marta M. Gámez-Fernández
- Bioactive release and modulation of urolithin metabotype A phenotype gut microbiota during in vitro digestion and fermentation of ellagic acid-rich fruit polyphenols July 3, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D4FO06221C, PaperZhike Xie, Feng Chen, Yawen Xiao, Jiaxin You, Xiaojun Zhou, Pei Li, Quancheng Zhou, Zheng RuanEllagic acid-rich fruits (EARF) are valued for their bioactive compounds, yet their gastrointestinal biotransformation remains insufficiently understood. This study investigated the functional transformation of phytochemicals, antioxidant effects, and microbial shifts...The content of this RSS […]Zhike Xie
- Analysis of human colostrum reveals differential co-occurrence networks of metabolites, microbiota and cytokines in maternal obesity July 1, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D4FO05637J, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.July S. Gámez-Valdez, Karina Corona-Cervantes, Erick S. Sánchez-Salguero, Mario R. Alcorta-García, Claudia N. López-Villaseñor, Rommel A. Carballo-Castañeda, Aldo Moreno-Ulloa, Víctor J. Lara-Díaz, Marion E. G. Brunck, Cuauhtémoc Licona-CassaniMaternal obesity alters colostrum bioactive molecules, exhibiting […]July S. Gámez-Valdez
- The effects of Lacticaseibacillus rhamnosus GG supplementation on gastrointestinal and respiratory outcomes: a systematic review and meta-analysis of randomized controlled trials July 1, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO01780G, Review ArticleKhemayanto Hidayat, Lili Zhang, Hong Wei, Weiguo Zhang, Liqiang Qin, Yangwenshan Ou, Nan LiThe efficacy of Lacticaseibacillus rhamnosus GG (LGG) in reducing diarrhea duration in children is well established. However, its preventive potential and broader therapeutic applications beyond pediatric diarrhea have not been...The content of this RSS Feed […]Khemayanto Hidayat
- Dietary freeze-dried beer prevents inflammation in DSS-induced chronic ulcerative colitis in mice June 30, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO01043H, PaperMaría Paredes-Sánchez, Rocío Muñoz-García, Javier Ávila-Román, Ana Lobo-Prieto, María del Mar Orta-Cuevas, Diego L. García-González, Victoria Vázquez-Román, Elena Talero, Marina Sánchez-HidalgoGraphic illustration of the antioxidant and anti-inflammatory effects of freeze-dried beer in LPS-stimulated macrophages and in a DSS-induced chronic colitis model.To cite this article before page numbers are assigned, […]María Paredes-Sánchez
- Consumption of polyphenols, lipid profile, and markers of lipid peroxidation in patients with COVID-19 June 29, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO00571J, PaperMargarete Almeida Freitas de Azevedo, Vanessa Brito Lira de Carvalho, Nayara Vieira do Nascimento Monteiro, Maísa Guimarães Silva Primo, Vitória Ribeiro Mendes, Luciana Melo de Farias, Mayara Storel Beserra de Moura, Laís Lima de Castro Abreu, Joyce Lopes Macedo, Poliana Cristina de Almeida Fonseca Viola, Emídio Marques de Matos […]Margarete Almeida Freitas de Azevedo
- Screening of Lactococcus lactis strains with hypoglycemic effects and evaluation of their protective mechanisms against glucose-induced type 2 diabetes in zebrafish June 27, 2025Food Funct., 2025, Accepted ManuscriptDOI: 10.1039/D5FO01005E, PaperHuiying Li, Huijing Chen, Jianquan Kan, Sameh Awad, Amel Ahmed Ibrahim, Zsolt Zalán, Muying DuType 2 diabetes mellitus (T2DM) is a major global health challenge, and probiotics represent a potential therapeutic avenue. This study screened three probiotic strains in vitro for their ability to...The content of this RSS Feed […]Huiying Li
- Effects of vegan diets and lifestyle on adult body composition: a narrative review June 26, 2025Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO01876E, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Boštjan Jakše, Nataša Fidler Mis, Zlatko Fras, Derrick R. Tanous, Katharina WirnitzerThe health benefits of vegan diets are well documented, though achieving nutritional adequacy requires careful planning, as is the case with any […]Boštjan Jakše
- Synergy of Secoisolariciresinol diglucoside and fructooligosaccharide on enhancement of intestinal mucus barrier based on relieving ER stress and regulating gut microbiome July 10, 2025
