RSC – Nat. Prod. Rep. latest articles- S-Adenosylmethionine: considerations on its role in the origin and evolution of life January 19, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D5NP00079C, Highlight Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Andreas KirschningBiosynthetic considerations suggest that SAM biosynthesis occurred at an early stage of biological evolution. Fundamental processes such as methanogenesis, nitrogen fixation, and hydrogenation depend on SAM and may therefore have developed later.To […]Andreas Kirschning
- Marine natural products January 19, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D5NP00080G, Review ArticleAnthony R. Carroll, Brent R. Copp, Tanja Grkovic, Robert A. Keyzers, Michèle R. PrinsepA comprehensive review of 1256 new MNPs including a novel cytotoxic alkaloid PM742 from the sponge Discodermia sp.To cite this article before page numbers are assigned, use the DOI form of citation above.The content […]Anthony R. Carroll
- Diversity of enzymatic SAM-dependent C-methylation of aromatic compounds January 14, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D5NP00070J, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Juliane Breiltgens, Michael MüllerSAM-dependent C-methyltransferases that accept aromatic building blocks are highly diverse and selective, playing a crucial role for the diversification of natural products.To cite this article before page numbers are […]Juliane Breiltgens
- Green gold of the Pacific: unlocking compounds from terrestrial flora for antitumor and immunomodulatory drug discovery January 5, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D5NP00073D, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Paul Huchedé, Vincent Dumontet, Mariko MatsuiThis review highlights the Pacific region's terrestrial flora and explores its natural products as a source of novel antitumor and immunomodulatory compounds for drug discovery.To cite this […]Paul Huchedé
- Discovery, bioactivities and biosynthesis of spirooxindole alkaloids January 5, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D5NP00046G, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Ruijie Chen, Lihan Zhang, Xiaoyang Zhao, Zhuangjie Fang, Liping Zhang, Qingbo Zhang, Changsheng Zhang, Yiguang ZhuThis review provides a comprehensive summary of the origin, activities, and biosynthesis of spirooxindole-containing alkaloids derived from […]Ruijie Chen
- Discovery, engineering, and applications of amino acid and peptide prenyltransferases January 2, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D5NP00075K, Highlight Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Florian HubrichThis review highlights advances in the field of amino acid and peptide prenyltransferases, underscoring their value for chemoenzymatic peptide late-stage functionalization and drug development and showcasing their scope, promiscuity and engineering.To cite […]Florian Hubrich
- S-Adenosylmethionine: considerations on its role in the origin and evolution of life January 19, 2026
