RSC – Nat. Prod. Rep. latest articles- Non-strigolactone natural products interfering with parasitic weed development Tháng 6 28, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D5NP00077G, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Jesús G. Zorrilla, Antonio Cala Peralta, Mónica Fernández-Aparicio, Marco Masi, Francisco A. Macías, Alessio CimminoNon-strigolactone compounds regulate parasitic plant germination, growth, and host recognition, often acting synergistically with root signals. They also […]Jesús G. Zorrilla
- Visual cycle-derived bisretinoids as endogenous natural products: enzyme-free formation, photochemical reactivity, and retinal degeneration Tháng 6 28, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D6NP00038J, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Hye Jin Kim, Janet R. Sparrow, Young Pyo JangThis review reframes retinal bisretinoids as autochthonous natural products, demonstrating how polyene electrophilicity and non-enzymatic aza-electrocyclization dictate their inevitable biogenesis and subsequent photochemical toxicity.To […]Hye Jin Kim
- Asymmetric synthesis of 3,3-disubstituted oxindoles: methodologies and applications in natural product synthesis Tháng 6 25, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D6NP00015K, Review ArticleRui Yang, Lihua Wei, Zhiqiang MaThis review summarizes the diverse asymmetric strategies for constructing 3,3-disubstituted oxindoles and discusses their applications in natural product synthesis, with an emphasis on the construction of the key chiral intermediates.To cite this article before page numbers are assigned, use the DOI form […]Rui Yang
- Genomic scale analysis of assembly-line polyketide synthase diversity and evolution Tháng 6 25, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D6NP00052E, Review ArticleSeokyoung Lee, Chaitan KhoslaPKSClusterDB provides a curated genomic-scale catalogue of assembly-line PKSs, enabling anchor-window analysis that reveals family-resolved evolutionary patterns and helps interpret orphan pathways and biosynthetic diversity.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS […]Seokyoung Lee
- Biosynthetic crosstalk in bacteria: routes to chimeric natural products Tháng 6 25, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D6NP00048G, Highlight Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Wen-Chao Yu, Zhiyuan Peng, Yan-Song Ye, Qihao WuDistributed biosynthetic pathways can generate chimeric natural products missed by single cluster genome mining; multi-class metabolomics offers a route to identify these overlooked hybrid scaffolds.To cite […]Wen-Chao Yu
- Challenges and opportunities in the synthesis of biologically relevant flavonoids and their glycosides Tháng 6 18, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D6NP00008H, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Debabrata Giri, Saikat Mondal, M. Carmen Galan, Abhijit SauThis review provides a current perspective on the recent advancements in flavonoid chemistry and their role in the development of novel therapeutic agents.To cite […]Debabrata Giri
- The elansolids: how nature shows chemists how to tame p-quinone methides Tháng 6 18, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D6NP00030D, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Liang-Liang Wang, Xiao-Qin Zhou, Andreas KirschningUsing elansolids as a case study, it is demonstrated how nature tames the highly reactive p-quinone methide by controlling its reactivity and conformation in a very efficient […]Liang-Liang Wang
- Cinnamoyl-containing non-ribosomal peptides: discovery, bioactivity and biosynthesis Tháng 6 18, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D5NP00084J, Review ArticleYuyang Wang, Yanqing Li, Yingying Chen, Jianhua Ju, Zhuo Shang, Junying MaThe chemical diversity, biological activities, biosynthesis and expanding chemical diversity of cinnamoyl-containing non-ribosomal peptides.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The […]Yuyang Wang
- Decoding multidimensional regulatory networks in Streptomyces to accelerate natural product discovery and production Tháng 6 17, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D6NP00022C, Review ArticleYongjae Lee, Woori Kim, Chanyoung Joung, Hyeseong Kim, Namil Lee, Byung-Kwan ChoAdvances in genome-scale analytical tools have expanded our knowledge of regulatory networks in Streptomyces, providing a transferable framework for the systematic activation of biosynthetic gene clusters for natural product discovery and production.To cite this article before […]Yongjae Lee
- Mass spectrometry as the unifying force in natural product sciences Tháng 6 14, 2026Nat. Prod. Rep., 2026, 43,1070-1072DOI: 10.1039/D6NP90018F, EditorialMehdi A. Beniddir, Nadja B. Cech, Roger Linington, Neha GargMehdi A. Beniddir, Nadja B. Cech, Roger Linington and Neha Garg introduce the Natural Product Reports themed issue on Mass spectrometry metabolomics in natural products research.The content of this RSS Feed (c) The Royal Society of ChemistryMehdi A. Beniddir
- Emerging technologies for the discovery of biosynthetic genes in plants Tháng 6 10, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D6NP00011H, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Anne Jaczkowski, Arne Bültemeier, Benedikt Seligmann, Boas Pucker, Jakob FrankeCompared to microbial natural product research, elucidating biosynthetic pathways in plants requires distinct methodological approaches. This review describes emerging technologies for discovering biosynthetic […]Anne Jaczkowski
- Ecological context for bacterial natural products discovery Tháng 6 10, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D6NP00018E, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Jonathan Parra, Marla I. Macias-Contreras, Dulce G. Guillén Matus, Katherine R. DuncanThis review highlights recent studies and considerations towards ecological approaches to natural product discovery.To cite this article before page numbers are […]Jonathan Parra
- Hot off the Press Tháng 6 9, 2026Nat. Prod. Rep., 2026, 43,1073-1077DOI: 10.1039/D6NP90022D, Hot off the Press ArticleRobert A. Hill, Andrew SutherlandA personal selection of 32 recent papers is presented covering various aspects of current developments in bioorganic chemistry and novel natural products such as humupulusone A from Humulus lupulus.The content of this RSS Feed (c) The Royal Society of ChemistryRobert A. Hill
- Microbial biotransformation of plant-derived metabolites: mechanisms, pathways, and multi-omics integration Tháng 6 9, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D6NP00039H, Review ArticleYoungse Oh, Jaeyoun Lee, Soohyun Um, Seung Hyun KimThis review presents a reaction-class atlas of microbial biotransformations of plant-derived metabolites and highlights how enzymatic mechanisms and multi-omics approaches reveal metabolic diversity in complex microbial communities.To cite this article before page numbers are assigned, use the DOI form […]Youngse Oh
- Rare functional groups and unique scaffolds in Streptomyces natural products Tháng 6 7, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D6NP00012F, Review ArticleSanyuan Shi, Xuerui Jin, Gaoli Wang, Xuewei Hao, Jing Xie, Liujie Huo, Yunzi LuoThis review highlights Streptomyces natural products with rare functional groups, unique scaffolds, and atypical modifications, examining the enzymatic mechanisms to link biosynthetic diversity with synthetic biology applications.To cite this article before page numbers are […]Sanyuan Shi
- Advances in the discovery and functional analysis of Anti-infective and immunomodulatory natural products from host-associated microbiomes Tháng 6 4, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D6NP00003G, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Sebastian Götze, Christine BeemelmannsThis review highlights discoveries from 2018 to 2025 of microbiome-derived natural products with anti-infective and immunomodulatory actvities, and urges to more targeted OMICs approaches to fully harness the encoded […]Sebastian Götze
- Natural products with atypical atoms: unveiling structures, biosynthetic pathways, and bioactivities Tháng 6 3, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D5NP00083A, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yeo Jin Lee, Hyeon-Jeong Hwang, Jungro Lee, Hyeon Seung Park, Juwan Son, Mohammad Seyedsayamdost, Munhyung Bae, Seoung Rak Lee, Yun KwonRare elements in natural products unlock new chemical space, biosynthetic logic, and […]Yeo Jin Lee
- Inverse stable isotopic labeling for natural product characterization and discovery Tháng 6 2, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D6NP00014B, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jose Miguel D. Robes, Aaron W. PuriThis review highlights applications of inverse stable isotope labeling in natural product research, including biosynthesis, structural elucidation, and discovery, spanning 2005 to 2026.To cite this article […]Jose Miguel D. Robes
- Synthetic biology as a game-changer for endangered medicinal orchids: biosynthesis, engineering and conservation Tháng 6 1, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D6NP00027D, Review ArticleLin Qiu, Xianghui Chen, Zhan Luo, Min Jiang, Hu Chen, Biyu Hou, Haizheng Yu, Ning Li, Lei ZhangSynthetic biology acts as a game-changer for endangered medicinal orchids, enabling a transition from resource scarcity and extraction inefficiency to sustainable conservation through pathway decoding, chassis engineering and green biomanufacturing.To […]Lin Qiu
- Unlocking hidden enzymatic chemistry in natural product biosynthesis Tháng 6 1, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D6NP00034G, HighlightMicah Harris, Asher Paul, Edward KalkreuterThis highlight reviews many of the existing and emerging strategies for prioritizing and accessing novel enzymology from microbial biosynthesis.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society […]Micah Harris
- Non-strigolactone natural products interfering with parasitic weed development Tháng 6 28, 2026
