Nano silver and some medical applications

Nano silver used in medical



Silver has been used to treat medical conditions for over 100 years due to its natural antibacterial and antifungal properties. Nano silver range in size from 1-100 nm. They have a relatively large surface area, increasing the possibility of contact with bacteria or fungi and greatly improving its bactericidal and fungicidal effectiveness.

Antibacterial properties are recorded for some dangerous types such as: Gram-negative bacteria including genera

  • Acinetobacter (Actinobacillus pleuropneumoniae bacteria causes pleurisy, Acinetobacter baumannii bacteria causes meningitis, bloodstream infections, and pneumonia that can be resistant to many antibiotics…)
  • Escherichia (Escherichia Coli or E.coli is a type of bacteria that causes edema of the head (symptoms of swollen eyes, swollen forehead), diarrhea)
  • Pseudomonas (Pseudomonas aeruginosa bacteria cause blood infections, respiratory infections, urinary tract infections, pneumonia..)
  • Salmonella (Salmonella choleraesuis and Salmonella typhisuis cause paratyphoid with symptoms of goat feces and diarrhea.)
  • Vibrio ( alginolyticus; V. anguillarum; V. ordalii; V. salmonicida, V. parahaemolyticus, V. harvey, V. vulnificus cause septicemia and body redness in shrimp and fish. Vibrio cholerae infects the digestive tract, thereby causing cholera in pigs)

While gram-positive bacteria include genera such as

  • Clostridium (Clostridium perfringens causes enteritis, enterotoxin infection causing hemorrhage and then death)
  • Enterococcus (Enterococcus faecalis and faecium cause a variety of infections, including endocarditis, urinary tract infections, prostatitis, intra-abdominal infections, cellulitis, and surgical site infections and infectious diseases. blood infection).
  • Listeria (Listeria monocytogenes bacteria causes sepsis, digestive and absorption disorders, or causes meningitis and encephalitis.)
  • Staphylococcus (Staphylococcus hyicus, Staphylococcus aureus, Staphylococcus saprophyticus cause dermatitis in pigs)
  • Streptococcus (Streptococcus bacteria cause meningitis, septicemia, polyserositis, arthritis, endocarditis, and pneumonia.)

Ability to kill or inhibit some viruses:

  • Porcine diarrhea virus (PEDV),
  • Gastrointestinal transmissible gastritis virus (TGEV),
  • Arterivirus causes Blue Ear Disease in pigs,
  • Viruses of the Asfarviridae family cause African swine fever,
  • WSSV virus causes white spots on shrimp
  • Hepatitis B virus, hepatitis C virus, HIV virus

Nano silver is an effective and fast-acting agent against many common fungi, including genera such as Aspergillus, Candida and Saccharomyces.


Antibacterial mechanism: Nano silver when exposed to bacteria and fungi will affect cell metabolism and inhibit cell growth. Nanosilver prevents respiration, basic metabolism of electron transfer systems and substrate transport in microbial cell membranes. Nano silver inhibits the multiplication and growth of bacteria and fungi that cause infections, odors, itching and ulcers.

Antiviral mechanism: the antiviral activity of nanoparticles comes from their ability to bind to the glycoprotein of the viral envelope and inhibit the virus by binding to the disulfide bond regions of the virus. Besides the immediate interaction with viral surface glycoproteins, AgNPs can also enter cells and complete their antiviral activity through interaction with viral nucleic acids.

Furthermore, it has also been suggested that silver nanoparticles can also inhibit the production of viral RNA and extracellular virions in vitro. And it is commonly understood that Ag, in various forms, inactivates viruses by denaturing enzymes through reactions with sulfhydra, amino, carboxyl, phosphate and imidazole groups.


    • Wash open wounds

Wounds caused by falls, collisions, cuts by sharp objects, burns… cause uncomfortable burning pain and are at risk of infection and necrosis. Normally, to disinfect open wounds, people often use potassium permanganate, PVP iodine, hydrogen peroxide (H2O2), alcohol… However, when using the above substances, they often cause an extremely painful and uncomfortable feeling.

In addition, oxidizing antibacterial agents such as Potassium Permanganate, PVP iodine, and Hydrogen Oxygen both kill bacteria and cause healthy cell death by generating free radicals, so wounds heal longer. Substances that easily lose their effectiveness such as hydrogen peroxide and alcohol can also cause the wound to become re-infected…

Nano silver is known for its broad-spectrum antibacterial ability, is safe, does not cause pain, does not produce free radicals and has the ability to create biofilm very quickly, so wounds disinfected with nano silver dry quickly. than traditional disinfectants.

Besides, silver nanoparticles are not decomposed by light and do not evaporate like alcohol or hydrogen peroxide. Long enough survival time helps control reinfection better

How to use:

Take 100 ml of 1000 ppm nano silver, add it to 1 liter of clean water and stir until completely dissolved. Obtain an orange solution of 100 ppm nano silver.

Use the solution to clean the wound, then use gauze to cover the wound. Putting nano silver solution on the bandage at the wound site helps the wound heal and not be scratched until the wound is completely healed.

Especially effective for foot wounds in diabetic patients


  • Nano silver eliminates foot odor, armpit odor, and foot fungus

Legs and armpits are two places that easily sweat, sweat contains mineral salts and proteins. High humidity and nutrients are favorable conditions for bacteria to grow. Bacteria eat proteins and emit gases such as H2S, NH3… which are the main causes of unpleasant odors.

The market offers scented products to suppress odors. This approach only makes the problem worse. Or accompanying side effects such as yellow-stained clothes…

Nano silver kills bacteria, inhibits bacteria from growing, thereby cutting the cause of odor. Silver nanoparticles are not lost but stick to the skin, helping to effectively kill and inhibit bacteria for 24-48 hours.

How to use:

Take 500 ml of 98% alcohol and add it to 500 ml of clean water, shake well until the alcohol dissolves into the water completely. Then slowly add 20 ml of 1000 ppm nano silver solution and stir well until completely dissolved. Obtain 1 liter of 20 ppm nano silver solution with lemon yellow color.

The addition of alcohol helps dry quickly and avoids an uncomfortable wet feeling

Use that 20 ppm nano silver solution to spray on your armpits, shoes, socks and soles of your feet. (Bathing and washing your feet before use to remove existing fungal spores will be more effective).

  • Nano silver treats symptoms of hemorrhoids

Hemorrhoid patients often experience burning pain, itching, and even bleeding. The cause is because the area around the wound is infected.

Bacteria secrete enzymes to decompose proteins, enzymes that normally contain acid. The greater the density of bacteria, the higher the acidity. Causes skin damage, causing pain, burning, itching and discomfort.

To inhibit bacterial growth, you can use nano silver to spray directly after going to the toilet.

How to use:

100 ml of 1000 ppm nano silver mixed with 1 liter of clean water and stir well until completely dissolved. Obtain a 100 ppm nano silver solution with an orange color.

Using it after each trip to the toilet will help effectively resolve these symptoms.

  • Nano silver mouthwash

Using mouthwash helps prevent tooth decay and reduces bad breath. Current mouthwashes often use fragrant essential oils to help eliminate bad breath (menthol, cinnamon, lemongrass, etc.)

Normally, antibacterial agents are rarely used in mouthwash, because of concerns about health effects.

Safe nano silver is used by WHO to disinfect drinking water at 100 micrograms/mL (100 ppm).

How to use:

Add 100 ml of 1000 ppm nano silver to 1 liter of 0.9% physiological saline and stir well until completely dissolved. Use as a daily mouthwash to help prevent tooth decay and eliminate bad breath

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