Chemical Science

RSC – Chem. Sci. latest articles

• Access to arynes from arenes via net dehydrogenation: scope, synthetic applications and mechanistic analysis February 20, 2025
  Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC00054H, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Riley A Roberts, Bryan Metze, Nicole Javali, Theresa M. McCormick, David Ross StuartArynes undergo a wide range of chemical transformations making them versatile reactive intermediates for organic synthesis. Access to arynes has long […]
  Riley A Roberts
• Reversible Redox 19F Magnetic Resonance Imaging Nanoprobes for Monitoring Redox State in Vivo February 20, 2025
  Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D4SC08297D, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Xiaoyao Xiong, Sijia Li, Yumin Li, Suying Xu, Chang Guo, Leyu WangRedox processes are indispensable for physiology, and dysregulated redox balance is critical in various metabolic diseases. The development of imaging diagnosis tools […]
  Xiaoyao Xiong
• Multimeric, Multivalent Fusion Carrier Proteins for Site-Selective Glycoconjugate Vaccines Simultaneously Targeting Staphylococcus aureus and Pseudomonas aeruginosa February 20, 2025
  Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D4SC08622H, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Charlotte Sorieul, Bartal Mikladal, Dung-Yeh Wu, Cinzia Giovani, Giusy Adamo, Giacomo Romagnoli, Filippo Carboni, Roberto Adamo, Barbara Brogioni, Immaculada Margarit, Jeroen D Codee, Maria Rosaria RomanoStaphylococcus aureus and Pseudomonas aeruginosa are major antimicrobial-resistant […]
  Charlotte Sorieul
• Modulating the spin–flip rates and emission energies through ligand design in chromium(III) molecular rubies February 20, 2025
  Chem. Sci., 2025, Advance ArticleDOI: 10.1039/D4SC08021A, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yating Ye, Maxime Poncet, Polina Yaltseva, Pablo Salcedo-Abraira, Antonio Rodríguez-Diéguez, Javier Heredia Martín, Laura Cuevas-Contreras, Carlos M. Cruz, Benjamin Doistau, Claude Piguet, Oliver S. Wenger, Juan Manuel Herrera, Juan-Ramón JiménezThree homoleptic spin–flip (SF) […]
  Yating Ye
• Machine Learning-Driven Discovery of Highly Selective Antifungal Peptides Containing Non-Canonical β-Amino Acids February 20, 2025
  Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D4SC06689H, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Douglas H. Chang, Joshua D Richardson, Myung-Ryul Lee, David M. Lynn, Sean P. Palecek, Reid C Van LehnAntimicrobial peptides (AMPs) are promising compounds for the treatment and prevention of multidrug-resistant infections because of […]
  Douglas H. Chang
• Photocatalytic 1,3-Difluoroalkylcarboxylation of Alkenes by Triple Kinetic-Controlled Radical Self-Ordering February 19, 2025
  Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D4SC08607D, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Hong Fu, Zuo-Shuai Wang, Si-Jia Li, Lin-Yuan Zhu, Xiao-Jian Wang, Hong-Chen Wang, Bing HanA transition metal-free protocol for the unsymmetrical radical 1,3-difunctionalization of alkenes has been established for the first time in the […]
  Hong Fu
• Logic-gated approach for targeted delivery and site-selective activation of photothermal agents in precision cancer treatment February 19, 2025
  Chem. Sci., 2025, Advance ArticleDOI: 10.1039/D4SC08228A, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Chang Jiang, Zhengxiang Zhao, Amanda K. East, Suritra Bandyopadhyay, Ziyi Jiang, Jefferson ChanLogic-gated strategies represent a promising approach to achieving highly selective cancer therapies.To cite this article before page numbers are assigned, use […]
  Chang Jiang
• Electrically conductive charge-segregated pseudo-polymorphs comprising highly planar expanded π-electronic cation February 19, 2025
  Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D4SC07576E, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Yohei Haketa, Ryoya Nakajima, Yuto Maruyama, Hiroki Tanaka, Wookjin Choi, Shu Seki, Shunsuke Sato, Hitomi Baba, Yoshiki Ishii, Go Watanabe, Kirill Bulgarevich, Kazuo Takimiya, Kenzo Deguchi, Shinobu Ohki, Kenjiro Hashi, Takashi Nakanishi, Yukihide […]
  Yohei Haketa
• Formation of polysulfides as a smart strategy to selectively detect H2S in a Bi(III)-based MOF material February 19, 2025
  Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D4SC07144A, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Valeria B. López-Cervantes, Juan L. Obeso, J. Gabriel Flores, Aida Gutierrez-Alejandre, Raul A. Marquez, J. de los Reyes, Catalina V. Flores, N. S. Portillo-Vélez, Pablo Marín-Rosas, Christian A. Celaya, Eduardo González-Zamora, Diego Solis-Ibarra, […]
  Valeria B. López-Cervantes
• A Photo- and Cobalt-Catalyzed Highly Selective and Divergent Hydrofunctionalization of 1,3-Dienes with Phenols February 19, 2025
  Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC00438A, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Yue Wang, Junhao Miao, Honglin Dong, Dongliang Zhang, Bei Chen, Meihui Guan, Ge Zhang, Qian ZhangAn applicable cobalt-hydride mediated selective, divergent hydroetherification and sequential hydroetherification/hydroarylation of dienes with simple phenol feedstocks under photoredox […]
  Yue Wang
• Adaptive Representation of Molecules and Materials in Bayesian Optimization February 19, 2025
  Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC00200A, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Mahyar Rajabi Kochi, Negareh Mahboubi, Aseem Partap Singh Gill, Seyed Mohamad MoosaviBayesian optimization (BO) is increasingly used in molecular optimization and in guiding self-driving laboratories for automated materials discovery. A crucial aspect of […]
  Mahyar Rajabi Kochi
• An argument for abandoning the “allowed” and “forbidden” classification of electrocyclic reactions February 19, 2025
  Chem. Sci., 2025, Advance ArticleDOI: 10.1039/D4SC08748H, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Barry K. CarpenterThe energy gaps between “forbidden” and “allowed” mechanisms of routine electrocyclic reactions can be negligibly small.To cite this article before page numbers are assigned, use the DOI form of citation above.The […]
  Barry K. Carpenter
• Unusually air-stable copper(I) complexes showing high selectivity for carbon monoxide February 19, 2025
  Chem. Sci., 2025, Advance ArticleDOI: 10.1039/D5SC00237K, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Borna Saeednia, Aria M. Sragow, Yannan Lin, Colton J. Sheehan, Amy S. Metlay, Michael R. Gau, Samantha A. Dye, Sarah P. O'Konski, Thomas E. Mallouk, Ivan J. DmochowskiWe report two Cu(I)-tren host molecules […]
  Borna Saeednia
• A Switch-On Luminescent Europium(III) Probe for Selective and Time-Resolved Detection of Adenosine Diphosphate (ADP) February 19, 2025
  Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D4SC07188C, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Samantha E Bodman, Patrycja Stachelek, Umatur Rehman, Felix Plasser, Robert Pal, Stephen Jonathan ButlerAdenosine diphosphate (ADP) is a key product of two essential classes of biological reactions, catalysed by ATPases and kinases. This […]
  Samantha E Bodman
• Operando evidence on the chirality-enhanced oxygen evolution reaction in intrinsically chiral electrocatalysts† February 18, 2025
  Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D4SC07927B, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Felipe Garcés-Pineda, Jiahao Yu, Camilo A. Mesa, Sergi Plana-Ruiz, Daniel Ruano, Yunchang Liang, Magalí Lingenfelder, Sixto Giménez Juliá, Jose Galan-MascarosElectrolytic hydrogen is identified as a crucial component in the desired decarbonisation of the […]
  Felipe Garcés-Pineda
• Polarizable potential window at soft molecular interfaces as a quantitative descriptor for the water content in organic solvents February 18, 2025
  Chem. Sci., 2025, Advance ArticleDOI: 10.1039/D5SC00527B, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Siqi Jin, Lifang Yang, Sijia He, Taoxiong Fang, Xiaohang Sun, Dandan Cai, Qiong Hu, Xinjian Huang, Haiqiang DengPPW width is dictated by different probabilities of ion-water finger complex encountering with water molecules in […]
  Siqi Jin
• In Situ Raman Spectroscopic Studies of CO2 Reduction Reactions: From Catalyst Surface Structures to Reaction Mechanisms February 18, 2025
  Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC00569H, Review Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Dongao Zhang, Xuan Liu, Yu Zhao, Hua Zhang, Alexander V. Rudnev, Jian-Feng LiA bstractThe electrochemical CO2 reduction reaction (eCO2RR) has gained widespread attention as an important technology for carbon cycling and sustainable chemistry. […]
  Dongao Zhang
• A focus on copper depletion-induced cuproptosis for cancer therapy February 18, 2025
  Chem. Sci., 2025, Advance ArticleDOI: 10.1039/D5SC90034D, Commentary Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Hongjie ZhangCuproptosis occurs via copper overaccumulation and depletion. While overaccumulation is well studied, depletion is less so. Here, copper depletion-induced cuproptosis is examined (Zhou et al., Chem. Sci., 2025, https://doi.org/10.1039/D4SC04712E).To cite this article before […]
  Hongjie Zhang
• Heterogeneously Catalyzed Supramolecular Polymerization: Essential Roles of Nucleation and Fragmentation-Induced Autocatalysis in Chiral Transfer February 18, 2025
  Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D4SC07894B, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Peichen Shi, Ganyu Chen, Qiang Chen, Huiting Wu, Suixu Li, Xiaoyu Cao, Liulin Yang, Zhong-qun TianThe complexity of multi-component molecular assembly demands precise control strategies to enhance both efficiency and selectivity. Heterogeneous nucleation […]
  Peichen Shi
• Helix-Induced Full-color Circularly Polarized Luminescence Films with Multiple Information Encryption and Multi-stimuli Responsiveness February 18, 2025
  Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC00019J, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Shi-Yi Li, Yang Zong, Bing-Hao Liu, Na Liu, Zong-Quan WuThe development of full-color circularly polarized luminescence (CPL) materials is of great significance in the field of luminescent materials; however, it is difficult due […]
  Shi-Yi Li