RSC – Chem. Sci. latest articles- Enabling plasmon-assisted ammonia synthesis: from mechanistic insights to catalyst design December 13, 2025Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5SC05725F, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Wenqian Li, Miao Xu, Gang Chen, Xiaoping Chen, Jie-Sheng Chen, Tian-Nan YeAmmonia is a key component in fertilizer and chemical production, with its synthesis currently dominated by the energyintensive Haber-Bosch process. To address […]Wenqian Li
- Biomineralization-mimicking cooperative assembly for tailoring anisotropic hierarchically porous metal–organic frameworks December 12, 2025Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5SC06744H, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Ruigang Sun, Ji Han, Bin Zhao, Bohan Liu, Guangrui Chen, Haidong Xu, Baiqi Wang, Yanjing Gao, Song Lin Zhang, Yusuke Yamauchi, Xiaoxin Chen, Buyuan GuanAnisotropic hierarchically porous metal–organic frameworks (MOFs) with asymmetric morphologies […]Ruigang Sun
- Sulfonyl-tuned amino DASAs for targeted photophysical and photoswitching control December 12, 2025Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5SC07740K, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Alexander Karr, Hye Joon Lee, A. Talim G. Khan, Chloe Ramsperger, Cesar Reyes, Kelly Biv, Elias PicazoDonor–acceptor Stenhouse adducts (DASAs) are molecular photoswitches with applications spanning materials to molecular machines. Although structural modularity […]Alexander Karr
- Modulating the Resonance Structures Toward Highly Efficient Violet-Blue Organic Light-Emitting Diodes with Narrow Emission December 12, 2025Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5SC07474F, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Xinyu Wang, Hanlin Gan, Mingliang Xie, Wenle Tan, Pengfei Niu, Mingke Li, Xinru Liao, Bohan Wang, Lei Ying, Yue Yu, Yuguang MaThe spectral narrowing of organic fluorescence materials is a focus issue in […]Xinyu Wang
- Diastereoselective Synthesis of Cyclopropyl Sulfoxides via Hydrosulfenation December 12, 2025Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5SC08731G, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Liyan Yuwen, Jiazhong Tang, Yayu Qi, Tianyi Zou, Shaotong Zhang, Ya-Qian Zhang, Qingwei ZhangCyclopropyl sulfoxides, merging two privileged motifs in medicinal chemistry, remain synthetically challenging despite their pharmaceutical potential. Herein, we report a […]Liyan Yuwen
- Unveiling hydrogen-source-dominated CO2 electroreduction activity on nitrogen-doped carbon nanotubes December 12, 2025Chem. Sci., 2026, Advance ArticleDOI: 10.1039/D5SC08737F, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yifan Jiang, Jingyu Wang, Jiaqi Xiang, Haichuan He, Liren Xiong, Min Zhang, Mustapha Abdulhadi, Liu Deng, Shanyong Chen, You-Nian LiuEmploying protons as the hydrogen source rather than H2O over N-CNTs catalyst under acidic […]Yifan Jiang
- Directing Robust Built-in Electric Fields via Imine Linkage Orientation in COFs for Efficient Dehydrogenative Organic Transformation Coupled with H2O2 Photosynthesis December 12, 2025Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5SC08299D, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Chang He, Enwei Zhu, Weixu Liu, Yongfa Zhu, Chen ChenThe built-in electric field (IEF) could be improved via developing donor-acceptor (D-A) type COF photocatalysts, yet available modulation strategies remain limited and poor. Here, […]Chang He
- On-surface synthesis of Nitrogen-Doped Nanographenes Assisted by Self-Assembly December 11, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC07197F, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.María Tenorio, Cesar Moreno, Jesús Castro-Esteban, Manuel Vilas-Varela, Diego Peña, Aitor MugarzaDespite the vast literature of in-solution synthesized heterocyclic-based nanographenes, examples of their on-surface synthesized counterparts remain remarkably scarce. A major limitation is […]María Tenorio
- Unlocking the application potential of AlphaFold3-like approaches in virtual screening December 11, 2025Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5SC06481C, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Chao Shen, Xujun Zhang, Shukai Gu, Odin Zhang, Qinghan Wang, Gang Du, Yihao Zhao, Linlong Jiang, Peichen Pan, Yu Kang, Qingwei Zhao, Chang-Yu Hsieh, Tingjun HouAlphaFold3 (AF3) has revolutionized the paradigm for protein-ligand […]Chao Shen
- pH-responsive regulation of multiphase coacervate wetting via phase selective enrichment of fatty acids December 11, 2025Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5SC07783D, Edge Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Preeti Sharma, Pankaj Singh Patwal, Pavan KumarBiomolecular condensates with multiphasic architectures organize specific biomolecular processes in different compartments and dynamically reconfigure their structure to regulate their biological functions. Here, we employ multiphase coacervates […]Preeti Sharma
- Visible Photon Energy Storage by [2+2] Cycloaddition of Pd-Oxazolones December 11, 2025Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5SC07833D, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Qianfeng Qiu, Junichi Usuba, Wai Lean Koay, Vincent Conrad Oppenheimer, Man Wai Wu, Shao-Liang Zheng, Vinh Xuan Truong, Grace G. D. HanWe report a new class of ortho-palladated oxazolone complexes that capture and […]Qianfeng Qiu
- Lipid-regulated assembly mechanisms and functional energetics of the essential bacterial chaperone BamA December 11, 2025Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5SC07027A, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Anjana George, Anusree M Raj, Akanksha G Patil, Varsha Kumari, Radhakrishnan MahalakshmiBamA is the highly conserved essential outer membrane chaperone of all Gram-negative bacteria. Our understanding of the BamA machinery remains incomplete, delaying […]Anjana George
- Conformational Adaptability Enabled Higher-Order Self-Sorting Processes in Coordination Cages December 11, 2025Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5SC05568G, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Minaz Parbin, Vellaiyadevan Sivalingam, Ramkumar Venkatachalam, Dillip Kumar ChandUnderstanding the key role of conformational adaptability in biological processes is crucial to mimic the remarkable applications inherent to biological systems. Motivated by the efficacy […]Minaz Parbin
- Single-molecule imaging of small aggregates of IAPP in type 2 diabetes serum with rationally-designed antibody-like scaffolds December 11, 2025Chem. Sci., 2026, Advance ArticleDOI: 10.1039/D5SC01427A, Edge Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Jiacheng Lin, Yu P. Zhang, Sean Chia, David Klenerman, Pietro Sormanni, Michele VendruscoloThis study employs computational epitope scanning to design antibody-like constructs targeting IAPP, demonstrating their utility in inhibiting aggregation, binding IAPP species, […]Jiacheng Lin
- Differentiating urethane and urea bond activation in polyurethane foam acidolysis December 10, 2025Chem. Sci., 2026, Advance ArticleDOI: 10.1039/D5SC05599G, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Madeleine Davis, Kelsey Richardson, Zach Westman, Alan L. Stottlemyer, Christopher Letko, Nasim Hooshyar, Vojtech Vlcek, Phillip Christopher, Mahdi M. Abu-OmarPolyurethane foam contains urethane and urea bonds, yet their depolymerization kinetics have not been […]Madeleine Davis
- Chiral Lewis Base/Lewis Acid/Brønsted Acid Cooperative Catalysis Enabled Regio-and Enantioselective Electrophilic Sulfenylation/Semipinacol Rearrangement of Allenols December 10, 2025Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5SC06981E, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Zheng-Wei Wei, Qing-Yun Cai, Li-Miao Yang, Yu-Xuan Huo, Ze-Long Li, Xue-Qing Gong, Zhi-Min ChenA chiral sulfide/B(C6F5)3/phosphoric acid co-catalyzed highly regio- and enantioselective tandem electrophilic sulfenylation/semipinacol rearrangement of allenols is developed for the first […]Zheng-Wei Wei
- Polyterrylenes: synthesis and regioregularity effect on p-type charge transport and deep-red light photodetection in OFETs December 10, 2025Chem. Sci., 2026, Advance ArticleDOI: 10.1039/D5SC06452J, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Chitrak Ghosh, Minji Chung, Hayeong Park, Aniket Jitendra Talreja, Ullrich Scherf, Joon Hak Oh, Suman Kalyan SamantaDibromo derivatives of bay-substituted terrylene and polyterrylenes, were synthesized for the first time. Polyterrylenes were employed in […]Chitrak Ghosh
- Poly(beta-amino esters): Applications in immunology December 10, 2025Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5SC05951H, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Hulya Bayraktutan, Rafał Kopiasz, Amr ElSherbeny, Pratik Gurnani, Cameron AlexanderThe immune system is critical in safeguarding human health against a variety of external and internal threats, yet its dysregulation can lead to serious […]Hulya Bayraktutan
- Cross-scale understanding cascade electrocatalysis for carbon and nitrogen utilization December 10, 2025Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5SC09063F, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Shiping Li, Youyu Pang, Hongmei Li, Rui Yang, Zhaoyu Jin, Guihua Yu, Panpan LiCascade electrocatalysis is increasingly being recognized as a promising approach for achieving efficient and selective conversion of carbon and nitrogen […]Shiping Li
- Localization of the Au–Au bond strength in the triplet excited state of the [Au(CN)2−] oligomers revealed by ultrafast time-domain Raman spectroscopy December 10, 2025Chem. Sci., 2026, Advance ArticleDOI: 10.1039/D5SC05664K, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Li Liu, Hikaru Kuramochi, Munetaka Iwamura, Koichi Nozaki, Tahei TaharaFemtosecond time-domain Raman spectroscopy and DFT calculations examine the excited triplet [Au(CN)2−] oligomers from the dimer to pentamer, revealing stronger Au–Au bonds in the […]Li Liu
- Enabling plasmon-assisted ammonia synthesis: from mechanistic insights to catalyst design December 13, 2025
