RSC – Chem. Sci. latest articles- Palladium-catalysed asymmetric annulations of Morita-Baylis-Hillman carbonates with allenes or alkenes via migratory insertion October 16, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC06910F, Edge Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Jin-Yu Huang, Xin-Ting Qin, Han-Wen Rao, Zhi-Chao Chen, Lei Zhu, Qin Ouyang, Wei Du, Ying-Chun ChenAs one of the most versatile intermediates in organic synthesis, π-allylpalladium complexes have been extensively exploited in allylic […]Jin-Yu Huang
- Intelligent Molecular Logic Computing Toolkits: Nucleic Acid-Based Construction, Functionality, and Enhanced Biosensing Applications October 16, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC06176H, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yaxue Hu, Jinghui Zhang, Ke Shen, Wei Shen, Hian Kee Lee, Sheng TangMolecular logic computing is revolutionizing biosensing by enabling intelligent, programmable detection, moving beyond simple target recognition to advanced molecular-level information processing. […]Yaxue Hu
- Reconstruction chemistry of electrocatalysts under working conditions October 16, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC06605K, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Hui Chen, Lina Wang, Muhan Na, Xiaoxin ZouReconstruction is a common phenomenon in electrocatalytic processes, playing a critical role in determining catalytic activity and stability. With growing fundamental understanding of reconstruction chemistry, the […]Hui Chen
- Synergistic spin effects in medium-entropy Ni-Fe-Mn-Ce oxyhydroxides for seawater oxidation October 16, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC05118E, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Li-Yuan Xiao, Xue Bai, Zhenlu Wang, Jingqi GuanEfficient and durable oxygen evolution reaction (OER) electrocatalysis is essential for advancing sustainable seawater electrolysis. In this work, a high-performance Ni-Fe-Mn-Ce medium-entropy oxyhydroxide is constructed via […]Li-Yuan Xiao
- Recent advances in mono- and multi-nuclear photoluminescent Cu(I) complexes with nitrogen containing ligands and their stimuli responsiveness October 16, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC04685H, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Alessandra Forni, Daniele Malpicci, Elena Lucenti, Luca Zecchinello, Alessia Colombo, Elena CariatiLuminescent Cu(I)-derivatives represent a highly desirable alternative to their noble metal analogues in view of copper relative abundance and low environmental concerns, […]Alessandra Forni
- High-Performance Room-Temperature Molecular Switches Enabled by Resonant Tunnelling in Dithia-porphyrins October 16, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC04840K, Edge Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Kavita Garg, Nikshay Bisht, Praveen C. RamamurthyAchieving stable and reproducible single-molecule switches at room temperature remains a key challenge in molecular electronics. Conventional porphyrins, while attractive for their conjugated framework and versatile redox […]Kavita Garg
- Oxidation of C-H and O-H Bonds by a Copper Complex Inspired by the Cu(II)-Tyrosyl Species Formed in LPMOs October 16, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC07166F, Edge Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.David D Hebert, Daniel Ye, Issac Garcia-BoschCupric tyrosyl intermediates have been invoked as active oxidants in oxidase and oxygenase Cu-dependent metalloenzymes. Inspired by these natural oxidants, we report the proton-coupled electron transfer (PCET) […]David D Hebert
- Narrowing Emission Spectra Based on Indolocarbazole Molecular Model System: An Experimental and Theoretical Study † October 16, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC06069A, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yingbo Lv, Jingzhuo Bi, Runting Wang, Zhiqiang Yang, Xinqi Yang, Shuaiqiang Zhao, Shiyin Wang, Haichao Liu, Shi-Tong Zhang, Bing YangTo clarify the structure-property relationship of the narrowed emission spectrum, four indolocarbazole (IDCz) model […]Yingbo Lv
- Emergence of Fluorescent Aggregates Through Hierarchical Self-Assembly October 15, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC04688B, Edge Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Maëva Coste, Sébastien UlrichControlling the growth of functional supramolecular nano-structures in aqueous media is a current challenge both for developing soft materials and for understanding the emergence of complex macromolecules by self-organization. We...The […]Maëva Coste
- Self-doped and planar nitrogen-bay-functionalized perylene diimides: unravelling structure-property relationships October 15, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC06640A, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Kathryn Wolfe, Zachary T Gardner, Zachary Smith, Alexander Harrison, Chad Risko, Gregory Charles WelchBay-functionalized perylene diimides (PDIs) offer a strategy for modulating electronic properties in organic semiconductors but can suffer from core twisting […]Kathryn Wolfe
- Excitation-dependent circularly polarized luminescence triggered by selective excitation of achiral dichroic dyes in cholesterol liquid crystals October 15, 2025Chem. Sci., 2025, Advance ArticleDOI: 10.1039/D5SC07444D, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Lulu Li, Peiting Jiang, Lei Chen, Yang Li, Yixiang ChengExcitation-dependent (ExD) circularly polarized luminescence (CPL) holds great potential for applications in anti-counterfeiting and information encryption due to its low cost, ease of operation, […]Lulu Li
- A Modular Scaffold for Cellularly-Retained Fluorogenic Probes for Sensitive Cell-Resolved Bioactivity Imaging October 15, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC05388A, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Philipp Mauker, Lucas Dessen-Weissenhorn, Carmen Zecha, Nynke Anna Vepřek, Julia Ines Brandmeier, Daniela Beckmann, Annabel Kitowski, Tobias Kernmayr, Julia Thorn-Seshold, Martin Kerschensteiner, Oliver Thorn-SesholdHere, we develop a general design for high-quality fluorogenic activity […]Philipp Mauker
- Weakly Solvating Electrolytes: A Solvation-Centric Paradigm for Rechargeable Metal Batteries October 15, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC06221G, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Mehdi Karbak, Kyungmin Yim, Ying Shirley Meng, Yuyan Shao, Xu WuElectrolyte design has long followed a solvation-first paradigm that prioritizes solvents capable of maximizing salt dissociation and ionic conductivity, while treating interfacial degradation […]Mehdi Karbak
- Dynamics-based transition states reveal solvent cage effect and SN2 transition state motion in Lewis acid catalyzed stereoselective tertiary alcohol nucleophilic substitution reactions October 15, 2025Chem. Sci., 2025, Advance ArticleDOI: 10.1039/D5SC05616K, Edge Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Anthony J. Schaefer, Trevor Mallavia, Daniel H. EssThe stereo-determining nucleophilic attack transition state from the intimate ion pair has significant SN2 character with dynamically coupled nitrogen–carbon bond formation and leaving group ejection.To cite […]Anthony J. Schaefer
- Design Principles for Photoswitchable Fluorescent Dyads October 15, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC06258F, Edge Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Sili Qiu , Andrew T. Frawley, Kathryn G. Leslie, Xingyu Qiu, Harry Laurence AndersonPhotoswitchable fluorophores offer precise optical control for advanced imaging, yet the design criteria for an efficient photoswitchable fluorescent dye remain […]Sili Qiu
- Sequential oxidative dearomatization/asymmetric homologation: from simple naphthols to chiral benzocycloheptanes October 15, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC05865A, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Hongkun Zeng, Shiyang Li, Lichao Ning, Tao Huang, Xiaoming Feng, Lili LinAn oxidative dearomatization/asymmetric ring-expansion sequential approach is reported to synthesize chiral benzocycloheptanes from unfunctionalized simple β-naphthols under mild reaction conditions. This protocol […]Hongkun Zeng
- Multi-Technique Characterization of Rhodium Gem-Dicarbonyls on TiO2(110) October 15, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC04889C, Edge Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Moritz Eder, Faith J. Lewis, Johanna I. Hütner, Panukorn Sombut, Maosheng Hao, David Rath, Paul Ryan, Jan Balajka, Margareta Wagner, Matthias Meier, Cesare Franchini, Gianfranco Pacchioni, Ulrike Diebold, Michael Schmid, Florian Libisch, Jiri […]Moritz Eder
- Self-sorting systems of photoresponsive polymer micelles: isomerization drives reversible and switchable self-assembly October 15, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC06852E, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Rikuto Kanno, Makoto Ouchi, Takaya TerashimaHerein, we report self-sorting systems of photoresponsive polymer micelles obtained from amphiphilic statistical copolymers bearing hydrophilic poly(ethylene glycol) (PEG) chains and hydrophobic/photoresponsive azobenzene (Azo) groups. The PEG/Azo copolymers […]Rikuto Kanno
- Cyclopropylmethyl S-adenosyl-L-methionine: an enzymatic cyclopropylmethyl donor October 14, 2025Chem. Sci., 2025, Advance ArticleDOI: 10.1039/D5SC06767G, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Huimin Zhao, Nanhai Yu, Sican Wang, Min DongAn enzymatic strategy utilizing a cyclopropylmethyl-SAM analogue and engineered methyltransferases enables the late-stage incorporation of cyclopropylmethyl groups into bioactive molecules under mild conditions.To cite this article […]Huimin Zhao
- Heterologous expression of an in planta-upregulated gene cluster in the wheat pathogen Parastagonospora nodorum establishes the biosynthesis of methylene-bridged depsides October 14, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC05442G, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Hera Thao Nguyen, Nicolau Sbaraini, Joe Bracegirdle, Luke Smithers, Stephen A. Moggach, Daniel Vuong, Ernest Lacey, Peter S. Solomon, Joel Haywood, Andrew M Piggott, Yit-Heng ChooiDepsides are polyphenolic natural products commonly found in […]Hera Thao Nguyen
- Palladium-catalysed asymmetric annulations of Morita-Baylis-Hillman carbonates with allenes or alkenes via migratory insertion October 16, 2025
