RSC – RSC Chem. Biol. latest articles- Impact of Conjugation Strategy and Linker Density on Spermine AcDex Nanoparticle-Splenocytes Conjugates Performance July 29, 2025RSC Chem. Biol., 2025, Accepted ManuscriptDOI: 10.1039/D5CB00104H, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Yuchen Su, Ruoyu Cheng, Bowei Du, Mai O. Soliman, Hongbo Zhang, Shiqi WangA common approach in living medicines engineering is modifying cell surfaces with nanomedicines to form nanoparticle-cell conjugates. Despite various available strategies, […]Yuchen Su
- Achieving cell-type selectivity in metabolic oligosaccharide engineering July 28, 2025RSC Chem. Biol., 2025, Accepted ManuscriptDOI: 10.1039/D5CB00168D, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Michelle Marie B Helmeke, Rhianna L Haynie-Cion, Matthew Robert PrattMetabolic oligosaccharide engineering (MOE) has been a transformative technology, enabling the chemical labeling and subsequent analysis of glycans. Central to this method are […]Michelle Marie B Helmeke
- Applications of click and click-to-release chemistry in biomaterials to advance skin regeneration July 27, 2025RSC Chem. Biol., 2025, Accepted ManuscriptDOI: 10.1039/D5CB00065C, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Merel Gansevoort, Matthijs van de Waarsenburg, Thomas Boltje, Floris P. J. T. Rutjes, Toin H. van Kuppevelt, Willeke F. DaamenAchieving skin regeneration following destruction of the epidermis and dermis (e.g. full-thickness wounds) […]Merel Gansevoort
- Investigating the N-terminal linker histone H1 subtypes as substrates for JmjC lysine demethylases July 27, 2025RSC Chem. Biol., 2025, Accepted ManuscriptDOI: 10.1039/D5CB00083A, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Vildan Turkmen, Anthony Tumber, Eidarus Saleh, Samanpreet Kaur, Christopher J Schofield, Jasmin MecinovićMembers of the Jumonji C (JmjC) subfamily of non-heme Fe(II) and 2-oxoglutarate (2OG) dependent Nε-lysine demethylases haves established roles in catalysing […]Vildan Turkmen
- P450 cyptide synthase MpoB catalyzes the cross-linking of the YPW motif on the precursor peptide July 23, 2025RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D5CB00153F, Communication Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Abujunaid Habib Khan, Jabal Rahmat Haedar, Vic Kiselov, Viktors Romanuks, Gints Smits, Stefano Donadio, Chin-Soon PhanThe uncharacterized cytochrome P450 cyptide synthase MpoB from Micromonospora polyrhachis DSM 45886 catalyzes a cross-link between Tyr-C3 and […]Abujunaid Habib Khan
- Semi-enzymatic synthesis and application of 13C-isotopically labelled inositol-(1,4,5)-trisphosphate July 22, 2025RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D5CB00139K, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Atharva Patharkar, Meike Amma, Jaime Isern, Zoé Chaudron, Angélique Besson-Bard, Valérie Nicolas-Francès, Claire Rosnoblet, David Wendehenne, Peter Schmieder, Dorothea FiedlerIsotopically labelled [13C6]Ins(1,4,5)P3 was synthesised and applied as a tool to characterise enzymatic phosphorylation […]Atharva Patharkar
- Defining STING–sterol interactions with chemoproteomics July 20, 2025RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D5CB00171D, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Ian Ford, Miranda Villanueva, Min Sub Lee, Quan D. Zhou, Constance Yuen, Robert Damoiseaux, Steven J. Bensinger, Keriann M. BackusChemoproteomic and genetic approaches reveal sterol interactions with stimulator of interferon genes (STING)-sterol, with […]Ian Ford
- Photoactivatable and Photolabile Pharmacophores: Lessons Learned from Capsaicin July 18, 2025RSC Chem. Biol., 2025, Accepted ManuscriptDOI: 10.1039/D5CB00124B, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Nils Imse, Lucia Rojas, Cristina Gil Herrero, Sebastian Thallmair, JeongSeop Rhee, Nadja SimethLight-controlled molecules have become valuable tools for studying biological systems offering an unparalleled control in space and time. Specifically, the remote-controllable […]Nils Imse
- Synergy of triazolyl substituents at C1 and C3 of galactose for high-affinity and selective galectin-4C inhibition July 17, 2025RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D5CB00106D, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Alexander Dahlqvist, Rob Marc Go, Chandan Kishor, Hakon Leffler, Helen Blanchard, Ulf J. NilssonGalectin-4 differs from other galectins in carbohydrate-binding specificity, cellular and pathophysiological function, and roles in e.g. cancer progression, fibrosis, and […]Alexander Dahlqvist
- Discovery of an Exquisitely Selective WDR5 Chemical Probe Accelerated by a High-Quality DEL-ML Hit July 16, 2025RSC Chem. Biol., 2025, Accepted ManuscriptDOI: 10.1039/D5CB00109A, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Lasse Hoffmann, Christopher Lenz, Frederic Farges, Serah W. Kimani, Johannes Dopfer, Sabrina Keller, Martin P. Schwalm, Hanna Holzmann, Andreas Krämer, Aiping Dong, Fengling Lu, Irene Chau, Levon Halebelian, Matthias Gstaiger, Susanne Müller, Stefan […]Lasse Hoffmann
- Impact of Conjugation Strategy and Linker Density on Spermine AcDex Nanoparticle-Splenocytes Conjugates Performance July 29, 2025
