RSC – Lab Chip latest articles- Unveiling microbial single-cell growth dynamics under rapid periodic oxygen oscillations March 30, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00065C, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Keitaro Kasahara, Johannes Seiffarth, Birgit Stute, Eric von Lieres, Thomas Drepper, Katharina Nöh, Dietrich KohlheyerTime-resolved microbial growth analyses at single-cell resolution under temporally controlled O2 environments.To cite this article before page numbers are assigned, […]Keitaro Kasahara
- A Comprehensive Review of Competitive Lateral Flow Assays Over the Past Decade March 30, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D4LC01075B, Critical Review Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Julia Pedreira, Lourdes Rivas, Joan Comenge, Vasso Skouridou, Daniel Camprubí-Ferrer, Jose Muñoz, Ciara K. O' Sullivan, Alejandro Chamorro-Garcia, Claudio ParoloCompetitive lateral flow assays (LFAs) provide a versatile and cost-effective platform for detecting a […]Julia Pedreira
- Rock-on-a-chip: A novel method for designing representative microfluidic platforms based on real rock structures and pore network modelling March 27, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00119F, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Pablo A Godoy, Alirza Orujov, Aurora Perez Gramatges, Saman AryanaMicrofluidics is a key tool for studying pore-scale phenomena in porous media, with applications in oil recovery and carbon storage. However, accurately replicating rock pore […]Pablo A Godoy
- High throughput drug screening platform utilizing capillary and artery cell layered models based on tumor-vascular cell interactions March 27, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D4LC00950A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jihyeon Song, Yeji Lee, Min-Seok Kim, Giheon Ha, WonJun Jang, Ulziituya Batjargal, Young Gyun Kim, Han-Jun Kim, Junmin LeeInteractions between tumors and adjacent blood vessels are critical in the tumor microenvironment (TME) for influencing […]Jihyeon Song
- Seamless integration of CMOS microsensors into open microfluidic systems March 27, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D4LC01000K, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Raziyeh Bounik, Alex Erich Landolt, Jihyun Lee, Vijay Viswam, Fernando Cardes, Mario Matteo Modena, Andreas HierlemannAs traditional two-dimensional (2D) cell cultures offer limited predictive capabilities for drug development, three-dimensional (3D) tissue models, such as […]Raziyeh Bounik
- Leveraging dielectrophoresis in inertial flows for versatile manipulation of micro and nanoparticles March 25, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D4LC01037J, PaperHaotian Cha, Lingxi Ouyang, Xiangxun Chen, Yuao Wu, Xiaoyue Kang, Hongjie An, Weihua Li, Nam-Trung Nguyen, Jun ZhangThe manipulation of micro and nanoparticles has extensive applications in biomedical research, clinical diagnostics, environmental monitoring, drug discovery, and mining industry. Dielectrophoresis (DEP) utilises nonuniform electric fields to manipulate particles,...The content of […]Haotian Cha
- Visualization investigation of fluid transport in multiscale porous media for CO2-EOR based on microfluidic technology March 25, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00019J, PaperJianxiang Wang, Jiafeng Sun, Jiawei Shi, Bo BaoVisualizing CO2-EOR dynamics: Left—schematic of CO2 injection in reservoir pores. Right—in situ observations of oil displacement in microfluidic chips. Cross-scale effects boost miscible recovery to 100% but worsen channeling in immiscible floods.To cite this article before page numbers are assigned, use the […]Jianxiang Wang
- The effect of cyclic fluid perfusion on the proinflammatory tissue environment in osteoarthritis using equine joint-on-a-chip models March 24, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D4LC01078G, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Johannes Heidenberger, Eva I. Reihs, Jonathan Strauss, Martin Frauenlob, Sinan Gültekin, Iris Gerner, Stefan Tögel, Peter Ertl, Reinhard Windhager, Florien Jenner, Mario RothbauerThis joint on a chip model, integrating inflammatory stimuli and cyclic fluid […]Johannes Heidenberger
- A Novel Manual Rotating Fluid Control Mechanism in a Microfluidic Device with a Finger-Actuated Pump for dual-mode sweat sampling March 24, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00171D, PaperMohamed Ishag Hassan Gama, Saminu Abdullahi, Marwa Omer Mohammed Omer , Zhu Yang , wang xuzhong, Yousuf Babiker Mohamed Osman , Yuhang Liu, Jingzhen Li, Yingtian Li, Xing Gao, Zedong NieWearable sweat analysis using microfluidics offers a non-invasive approach for real-time health monitoring, with applications in chronic disease management, […]Mohamed Ishag Hassan Gama
- Integrated technologies for molecular profiling of genetic and modified biomarkers in extracellular vesicles March 21, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00053J, Critical Review Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Li Zhang, Chi Yan Wong, Huilin ShaoExtracellular vesicles (EVs) carry myriad cargoes including genetic biomarkers inherited from parent cells as well as EV modifications by other entities. Complementary technologies have been developed to […]Li Zhang
- Synthesis of phospholipid vesicles using an electrokinetic turbulent microreactor March 21, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D4LC00992D, PaperLiangying Han, Yueqiang Zhu, Jin'an Pang, Xuejing Wang, Shenghua Ma, Xiaojun Han, Kaige Wang, Wei ZhaoThis study presents a novel method for synthesizing phospholipid vesicles using an electrokinetic turbulent microreactor. Multilamellar and giant unilamellar vesicles can be simply produced with their size and morphology being controllable.To cite this article […]Liangying Han
- Luffa cylindrica-inspired powerless micropump: long-term, high-flow operation and energy-generation application March 20, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00068H, PaperJungjae Woo, Jeongmin Seo, Hyewon Cho, Soeun Park, Changsoo Han, Hyejeong KimA biomimetic micropump inspired by Luffa cylindrica enhances passive fluid transport by integrating a hierarchical porous aerogel and flow resistors, enabling controlled and sustained operation for microfluidics and energy generation applications.To cite this article before page numbers are […]Jungjae Woo
- Elevated interstitial flow in the cerebrospinal fluid microenvironment accelerates glioblastoma cell migration on a microfluidic chip March 20, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00015G, PaperWanting Hu, Hua Sun, Huibo Qi, Linkai Jiang, Kaining Zhang, Xiaomeng Jia, Yu Wang, Yu Xiang, Qionglin LiangIn the presence of interstitial flow (IF), changing both cell densities and the cellular environment results in increased cell motility, which indicates the reliability of microfluidic chips for modeling complex physiological environments.To […]Wanting Hu
- Microfluidic mimicry of the Golgi-linked N-glycosylation machinery March 20, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00005J, Communication Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Florin N. Isenrich, Marie-Estelle Losfeld, Markus Aebi, Andrew J. deMelloWe present a droplet-based microfluidic platform able to mimic the Golgi-linked N-glycosylation machinery along the secretory pathway.To cite this article before page numbers are assigned, […]Florin N. Isenrich
- Microfluidic organoid-slice-on-a-chip system for studying anti-cholangiocarcinoma drug efficacy and hepatorenal toxicity March 20, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D4LC00902A, PaperJie Liu, Guohua Wu, Di Wu, Lin Wu, Chenwei Sun, Wenlong Zhang, Qijun Du, Qinrui Lu, Wenqi Hu, Hongyu Meng, Zhi Luo, Guangzhi Liu, Bangchuan Hu, Haijie Hu, Shuqi WangOrganoid-slice-on-a-chip that integrated patient-derived cholangiocarcinoma organoids (CCOs) with recellularized tissue slices provides a biomimetic system for assessing anticancer drug efficacy […]Jie Liu
- Machine learning-assisted flexible dual modal sensor for multi-sensing detection and target object recognition in the grasping process March 19, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00020C, PaperWentao Dong, Kaiqi Sheng, Chang Chen, Xiaopeng QiuA flexible dual modal sensor based on machine learning has been developed for non-contact proximity sensing and contact pressure sensing, achieving high-precision recognition of the material and hardness of target objects.To cite this article before page numbers are assigned, use the DOI […]Wentao Dong
- Design and development of a modular centrifugal platform with adjustable mixing and automated position-switching for stepwise gradient elution in reversed-phase liquid chromatography March 18, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D4LC01038H, PaperChia-Tse Shih, Chih-Hsin ShihAdjustable mixing and automated position-switching enable the efficient generation of eluents with varying compositions and the collection of eluates at each elution step.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal […]Chia-Tse Shih
- A biosensor-integrated filtration device for nanoparticle isolation and label-free imaging March 14, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00089K, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Leyang Liu, Takhmina Ayupova, Saurabh Umrao, Lucas D. Akin, Han-Keun Lee, Joseph Tibbs, Xing Wang, Utkan Demirci, Brian T. CunninghamWe report a biosensor-integrated recovery device (BIRD) that isolates and detects HIVs from plasma with […]Leyang Liu
- Intraluminal pressure triggers a rapid and persistent reinforcement of endothelial barriers March 13, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00104H, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Aurélien Bancaud, Tadaaki Nakajima, Jun-Ichi Suehiro, Baptiste Alric, Florent Morfoisse, Jean Cacheux, Yukiko T. MatsunagaWe directly measure the permeation flow across microvessels and demonstrate that intraluminal pressure triggers an active response in the endothelial […]Aurélien Bancaud
- MagSity platform: a hybrid magnetic levitation-based lensless holographic microscope platform for liquid density and viscosity measurements March 13, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00144G, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Oyku Doyran Ince, H. Cumhur TekinA portable lensless holographic microscope integrated novel magnetic levitation-based MagSity platform was introduced for precise, rapid and cost-effective liquid viscosity and density measurement.To cite this article before page numbers […]Oyku Doyran Ince
- Unveiling microbial single-cell growth dynamics under rapid periodic oxygen oscillations March 30, 2025
