RSC – Lab Chip latest articles- Microchannel-confined droplet-based electricity generator for biomechanical energy conversion and sensing August 25, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00662G, PaperJianwu Wang, Yonghui Zhang, Xiaokai Li, Zhengyu Li, Yuheng Li, Jiahao Zhang, Xin Liu, Jing Sun, Huanxi ZhengA flexible microchannel-confined droplet-based electricity generator (MC-DEG) is proposed, enabling biomechanical energy conversion and physiological signal monitoring.To cite this article before page numbers are assigned, use the DOI form of citation above.The […]Jianwu Wang
- Salvinia-Inspired Architectures for Enhancing Interface Stability and Mass Transfer in Microchannels August 21, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00599J, PaperJinlong Xu, Yongjian Li, Haosheng ChenMass transfer in conventional microchannels primarily relies on wall-mediated diffusion or is compromised by dynamic instability at free interfaces, which limits interphase transport efficiency. Inspired by the hierarchical trichomes of...The content of this RSS Feed (c) The Royal Society of ChemistryJinlong Xu
- Correction: Magnetically controllable 3D microtissues based on magnetic microcryogels August 21, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC90080H, Correction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Wei Liu, Yaqian Li, Siyu Feng, Jia Ning, Jingyu Wang, Maling Gou, Huijun Chen, Feng Xu, Yanan DuTo cite this article before page numbers are assigned, use the DOI form of citation above.The content […]Wei Liu
- Mine-on-a-chip: megascale opportunities for microfluidics in critical materials and minerals recovery August 21, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00387C, Perspective Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Wen SongThe rising demand of mineral resources essential to the functionality of low-carbon energy technologies – critical minerals – and the security of their supply poses one of the most pressing...The content of this […]Wen Song
- kappa(κ)Chip: A modular microfluidic device for analyte screening using a parallelized assays and multiple shear rate approach August 21, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00349K, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jose Wippold, Mark Kozlowski, Joe La Fiandra, Jessica Boetticher, Alison Grafton, Justin P. Jahnke, Joshua A. OrlickiPolymers are ubiquitous in the modern world, but many have low surface energies, making it difficult to engineer […]Jose Wippold
- Trapping nanoscale particles via quasi-Scholte mode in acoustofluidics August 20, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00490J, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Jiaqi Liu, Yuan Yu, Rujun Zhang, Yanru Chen, Yanlong Guo, Yi Zhang, Ran Tao, Jing-Ting Luo, Hairong Zheng, Pingfa Feng, Yong Qing Fu, Jianjian Wang, Feiyan CaiNon-contact and label-free acoustic manipulation of particles is […]Jiaqi Liu
- A hybrid flowing water-based energy generator inspired by rotatable waterwheel August 20, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00476D, PaperHongbo Wang, Hangchen Liu, Yuxin Song, Xuezhi Qin, Yang Li, Kairui Tang, Huanxi Zheng, Wanghuai Xu, Zuankai Wang, Baoping ZhangThe ever-increasing global demand for low-carbon energy underscores the urgency of water energy harvesting. Despite intensive progress, achieving continuous and efficient water energy harvesting — particularly from abundant, distributed, and...The […]Hongbo Wang
- Disruption and Nebulization of Lipid Vesicles Using Surface Acoustic Waves for Direct Mass Spectrometry August 19, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00692A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yuqi Huang, Qian Ma, Ashton Taylor, Lucas Lienard, Theresa Evans-Nguyen, Venkat R. BhethanabotlaCharacterizing extracellular vesicles (EVs) using Mass Spectrometry (MS) provides several advantages. The molecular compositions within EVs can be analyzed at very low […]Yuqi Huang
- Modular RCA-CRISPR/Cas12a Amplification on a Multi-Volume SlipChip for Ultrafast, Single-Copy Quantification of circRNA and miRNA in Ovarian Cancer August 19, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00585J, PaperLingxi Tian, Yan Gao, Yang Lu, Feng Xu, ZiRui Feng, Lihan Zi, Zaian Deng, Jun YangThe aberrant expression of RNAs in ovarian cancer (OC) progression highlights their potential as clinical biomarkers. However, rapid and accurate quantification of these RNAs in biosamples remains a significant challenging....The content of this RSS […]Lingxi Tian
- Oxygen-tunable endothelialized microvascular chip to assess hypoxia–reperfusion in sickle cell disease August 19, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00211G, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Samantha R. Schad, Joan D. Beckman, Wilbur A. Lam, David K. WoodA microfluidic platform combining endothelialized microchannels and on-chip oxygen control. The devices is used in this work to study hypoxia–reperfusion injury in sickle […]Samantha R. Schad
- CandyCollect Open to Closed (O2C) Microfluidic System for Rapid and User-Centric Detection of Group A Streptococcus August 18, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00253B, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Kelsey May Leong, Juan Carlos Sanchez, Cosette Craig, John A Tatka, René R Arvizu, Ingrid H Robertson, Victoria A M Shinkawa, Timothy R Robinson, Megan Chang, Xiaojing Su, Sanitta Thongpang, Ashleigh Theberge, Erwin Berthier, […]Kelsey May Leong
- Bubble removal in microfluidic channels surrounded by gas-permeable media: experiments and a predictive model August 18, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00407A, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Ludovic Keiser, Loukas Stamoulis, Baptiste Georjon, Philippe Marmottant, Benjamin DolletImbibition of a wetting liquid in five dead-end channels. Air is trapped in each channel (dark regions) and progressively expelled by an advancing meniscus (visible […]Ludovic Keiser
- Wearable and implantable microfluidic technologies for future digital therapeutics August 18, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00525F, Critical ReviewSanghoon Lee, Won Gi Chung, Enji Kim, Eunmin Kim, Joonho Paek, Dayeon Kim, Seung Hyun An, Taekyeong Lee, Jung Ah Lim, Jang-Ung ParkRecent advances in wearable and implantable microfluidics enable real-time sensing, drug delivery, and closed-loop therapy, with emerging trends in stretchability, multimodal integration, and AI-driven data processing.To […]Sanghoon Lee
- Mechanical Actuation on Surface (MAOS) Microfluidics: Compress to Preparation for Next-Generation Sequencing August 18, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00625B, PaperParimala Nagaraja, Rohit Lal, Cheng-Chang Lee, Eduardo Cervantes, Fay Christodoulou, Mais J. JebrailWe present Mechanical Actuation on Surface (MAOS), a programmable microfluidic platform that manipulates droplets via localized mechanical compression—eliminating the need for embedded electronics or fixed microchannel geometries. MAOS integrates essential...The content of this RSS Feed (c) The […]Parimala Nagaraja
- An open source for multiplexed, stable and transient flows to advance life science using microfluidic control automation August 18, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00551E, PaperJunichi Murai, Mahmoud Abdelmoez, Keisuke Kondo, Kohei Takamuro, Keiji Nozaki, Tim Schiller, Thomas Scheibel, Keiji Numata, Hisano Yajima, Kanako Terakado Kimura, Takao Hashiguchi, Taikopaul Kaneko, Misa Minegishi, Shintaku HirofumiMultiplexed fluid control is a demanding task in various life sciences and bioengineering research. We here present an open-source microfluidic sequence automation […]Junichi Murai
- 3D Holographic Flow Cytometry measurements of Microalgae: Strategies for Angle Recovery in Complex Rotation Patterns August 17, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00559K, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Francesca Borrelli, Giusy Giugliano, Emilie Houliez, Jaromir Behal, Daniele Pirone, Leonilde Roselli, Angela Sardo, Valerio Zupo, Maria Costantini, Lisa Miccio, Pasquale Memmolo, Vittorio Bianco, Pietro FerraroMarine ecosystems are in the spotlight, because environmental changes […]Francesca Borrelli
- Impact of sequential bifurcations on the cell-free layer of healthy and rigid red blood cells August 17, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D4LC00865K, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Yazdan Rashidi, Christian Wagner, Steffen M. RecktenwaldThis study examines how inlet branch length influences red blood cell distribution and cell-free layer formation in sequential microfluidic bifurcations, highlighting the role of channel geometry and RBC […]Yazdan Rashidi
- A High-Sensitivity and Clogging-Free Microfluidic Impedance Flow Cytometer based on Three-Dimensional Hydrodynamic Focusing August 17, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00571J, CommunicationXiao Chen, Tingxuan Fang, Yimin Li, Jie Zhang, Xiaoye Huo, Junbo Wang, Xuzhen Qin, Yueying Li, Yi Zhang, Jian ChenMicrofluidic impedance flow cytometry has functioned as an enabling instrument in single-cell analysis, which, however, suffers from the limiting tradeoff between high sensitivity and clogging free. In order to address...The […]Xiao Chen
- Integrated Physics-Based Modeling and Microfluidics for Quantifying Multiphase Carbonate Dissolution in Rocks August 14, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00557D, PaperJunyoung Hwang, Siqin Yu, Cynthia M Ross, Ilenia BattiatoAcid dissolution of carbonate formations is critical to the energy transition and relevant to many engineering applications. The dynamics of the dissolution reaction are complex, strongly depend both on the...The content of this RSS Feed (c) The Royal Society of ChemistryJunyoung Hwang
- Morphing out-of-surface channels enable strain-based control over fluid flow in skin-mountable patches August 14, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00417A, PaperRANA ALTAY, Hudson Gasvoda, Max Mailloux-Beauchemin, Johanna Brown, Kari Olson, Ismail Emre AraciThe volume of natural materials increases under tension, thus conventionally biomechanical actuation of fluidic pumps relies on compression for pressure generation. Here, we report on out-of-surface microchannels (OSMiCs) that exhibit...The content of this RSS Feed (c) The […]RANA ALTAY
- Microchannel-confined droplet-based electricity generator for biomechanical energy conversion and sensing August 25, 2025
