RSC – Lab Chip latest articles- Acoustic Microstreaming and Augmentation of Gas Exchange by Oscillating Membrane towards Microfluidic Artificial Lung May 28, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00109A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Anthony Mercader, Sung Kwon ChoThis paper presents a novel configuration for generating acoustic microstreaming flows at audible frequencies within a microchannel utilizing a pinned oscillating membrane. The characterizations and interactions of these acoustic streaming...The […]Anthony Mercader
- In Situ Electrochemical Measurement of Alkaline Phosphatase Activity in Engineered Gut Models Using a Porous Membrane Electrode Device May 27, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00341E, PaperYoshinobu Utagawa, Takeo Miyake, Yasuhiko Shinoda, Masateru Yamazaki, Hiroya Abe, Hitoshi Shiku, Kosuke InoIn vitro assays utilizing human cells have attracted attention as alternatives to animal testing for drug screening. Microphysiological systems (MPS) have been proposed as cell culture platforms that more closely...The content of this RSS Feed (c) […]Yoshinobu Utagawa
- An in vivo mimetic Liver-Lobule-Chip (LLoC) for stem cell maturation and zonation of hepatocyte-like cells on chip. May 27, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D4LC00509K, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Philip Dalsbecker, Siiri Suominen, Muhammad Asim Faridi, Reza Mahdavi, Julia Johansson, Charlotte Hamngren Blomqvist, Mattias Goksor, Katriina Aalto-Setälä, Leena E Viiri, Caroline Beck AdielsIn vitro cell culture models play a crucial role in preclinical […]Philip Dalsbecker
- Droplet Microfluidics-Assisted Fabrication of Fe-Alginate Microgels with Complex Morphology: Effect of the Compositions of Droplets May 27, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D4LC01101E, PaperJie Chen, Penghui Li, Ran An, Aishan Cai, Kaiqi Wang, Zheyu Zhang, Tao Wang, Yuandu HuAlthough shape-controllable alginate-based microgels via droplet microfluidics have been widely investigated, those studies have mostly focused on tuning the designs of microfluidic devices and parameters of the crosslinking media, very...The content of this RSS […]Jie Chen
- Enhancing Cancer Cell Immunocapture on Orientation-controlled Nanoimprinted Microcone Arrays in Microgap Channels May 27, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00143A, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Yuhei Saito, Natsumi Shimmyo, Shuhei Aoyama, Rie Utoh, Minoru Seki, Masumi YamadaCancer detection through circulating tumor cell (CTC)-based liquid biopsy has been expected to be a new modality for less-invasive, next-generation diagnosis. However, due […]Yuhei Saito
- A multi-channel wearable sensing patch based on gate-all-around field-effect transistors May 27, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00162E, PaperZhe Xing, Qiang Liu, Bo Lin, Shuang Li, Yuxin Liu, Guanyang Zhang, Wenjie Yu, Zhenhua Wu, Hongju MaoA multi-channel wearable sensing patch based on gate-all-around field-effect transistors that enables comprehensive health monitoring.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of […]Zhe Xing
- A combined digital microfluidic test for assessing infection and immunity status for viral disease in saliva May 26, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00308C, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.N. Sathishkumar, Jose Gilberto Camacho Valenzuela, Nguyen H. Le, Anthony K. C. Yong, Martin A. Rossotti, Joshua Dahmer, Alexandros A. Sklavounos, Martin Plante, Daniel Brassard, Lidija Malic, Anna N. Moraitis, Ruzica Biga, Imane El […]N. Sathishkumar
- Late-stage placental barrier model for transport studies of prescription drugs during pregnancy May 26, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00075K, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Sonya Kouthouridis, Poonam Saha, Madeleine Ludlow, Brenda YN Truong, Boyang ZhangThroughout pregnancy, the placental barrier is crucial for fetal development, evolving continuously to meet the growing nutritional demands of the fetus. Although the placenta […]Sonya Kouthouridis
- A three-dimensional microfluidic device embedded within a thermal cycler tube for electrokinetic DNA extraction May 26, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D4LC01062K, CommunicationQi Jiang, Xuehao Zang, Yilu Wang, Alexandre Sivassangarin Avaro, Diego Antonio Huyke, Juan Gabriel SantiagoMicrofluidic devices have been widely used in modern chemical and biological analyses as stand-alone units, typically in series with other equipment such as extraction columns, manual or robotic pipetting, and...The content of this RSS Feed […]Qi Jiang
- A 3D Patternoid Model for the Reproducible Characterization of Invasive Phenotypes and Drug Sensitivity in PDAC May 25, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00203F, Communication Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Sophie Christin Kurzbach, Violetta Carvajal-Heckele, Andreas R. Bausch, Maximilian Reichert, Tetsuhiko TeshimaPancreatic ductal adenocarcinoma (PDAC) is a highly invasive and heterogeneous malignancy, posing challenges for reproducible modeling and functional phenotypic analysis. To address these […]Sophie Christin Kurzbach
- Semi-permeable membrane stabilized microfluidic plasma chip for continuous, tunable synthesis of sub-10 nm nanoparticles May 22, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D4LC00960F, CommunicationYu Liu, Xiaoyi Zeng, Hongjun Liu, Zhen Liu, Jiayan Zhuang, Chunhui Wu, Zijun Chen, Ji Tae Kim, Xin Tang, Xing ChengA microplasma integrated microfluidic chip with a semi-permeable membrane stabilized the plasma/liquid interface, enabling an additional adjustment approach for uniform, precise, and tunable nanoparticle synthesis.To cite this article before […]Yu Liu
- Development of on-chip cell domes using Ca-alginate hydrogel shells for non-adherent cell studies May 22, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00204D, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Shinji Sakai, Hiroyuki Fujiwara, Ryotaro Kazama, Riki Toita, Satoshi FujitaWe present a facile method to fabricate stable Ca-alginate hydrogel domes covalently immobilized on glass plates. The system supports non-adherent cell proliferation and reagent delivery, […]Shinji Sakai
- Denaturation methods for reusable magnetic biosensors May 22, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00040H, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Suhyeon Park, Songeun Kim, Shan X. Wang, Jung-Rok LeeWe investigated the effectiveness of various denaturants, including ultrapure water, urea solution, tris-ethylenediaminetetraacetic acid buffer, and dimethyl sulfoxide, for the denaturation of target DNAs hybridized to […]Suhyeon Park
- Mechanical regulation of nerve stem cells multiple behaviors via GHz acoustic streaming May 21, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D4LC00867G, PaperWenjun Li, Shenghui Kang, Wei Wei, Kai Yang, Xiaoyu Wu, Shan He, Zefang Wang, Wenlan Guo, Chen Sun, Wei Pang, Xuexin Duan, Yanyan WangMechanical regulation the behavior of neural stem cells is important for cellular transplantation and neural regenerative medicine, how neural stem cells perceive and respond to mechanical […]Wenjun Li
- Halochromism of Rosolic Acid: a pH-Sensitive Colorimetric Dye Combined with the Smartphone Technique for Quantification of DNA in Molecular Diagnostics May 21, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00036J, PaperSivakumar Rajamanickam, Seo Yeon Park, Seung Kyun Park, Nae Yoon LeeInfectious foodborne pathogens are responsible for serious illnesses and socioeconomic losses worldwide, making early detection crucial to control excessive damage. Colorimetric loop-mediated isothermal amplification (LAMP) assays are a promising molecular...The content of this RSS Feed (c) The Royal Society […]Sivakumar Rajamanickam
- 3D-printed micro-pore evaporator for increasing concentration of analytes in aqueous solutions May 19, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00329F, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yufeng Su, Tanya HutterThis study presents a micro-3D printed concentrator with micro-pores for solvent evaporation, designed for low-temperature, small-volume sample processing.To cite this article before page numbers are assigned, use the DOI form of […]Yufeng Su
- A multi-channel chip enabled synchronized reciprocating-flow of fluid for rapid, simultaneous, multiplex detection of inflammatory markers May 19, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00132C, PaperJuanhua Li, Zihan Xiao, Tianyu Wu, Yiren Liu, Wenyong Zhang, Cuiping Zhou, Yanqiong Su, Hongrui Liang, Donglin Cao, Jianhua ZhouInfections are common in daily life and can lead to various acute diseases with complex symptoms. Rapid and accurate detection of multiple inflammatory markers using multi-channel microfluidic chips provides important...The […]Juanhua Li
- Rapid screening of CO2 capture fluids May 18, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D4LC00772G, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yaohao Guo, Feng Li, Sepehr Saber, Mohammad Zargartalebi, Siyu Sonia Sun, Yurou Celine Xiao, Bo Bao, Zhi Xu, David SintonHigh-throughput evaluation of CO2 capture fluids accelerates the development of next-gen carbon capture technologies.To cite […]Yaohao Guo
- Investigation of the potential application of kaemperide in hyperuricemia based on a kidney-on-a-chip May 16, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D4LC01086H, PaperXinyu Song, Lili Zhao, Yingying Tian, Chen Yang, Ting Cao, Jiayu ZhangHyperuricemia (HUA), a serious metabolic disease that manifests as an elevated serum uric acid (SUA) level, is closely related to gout, hypertension, diabetes, coronary heart disease, chronic kidney disease, and other conditions.To cite this article before page numbers […]Xinyu Song
- Compartmentalized perfusion for temporal control of the chemical microenvironment of iPSC-derived cardiac cells May 14, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00072F, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Kaisa Tornberg, Wolfram Grötsch, Niina Ritari, Saara Haikka, Lassi Sukki, Katriina Aalto-Setälä, Mari Pekkanen-Mattila, Pasi KallioOrgan-on-chip structure for compartmentalized perfusion.To cite this article before page numbers are assigned, use the DOI form of citation […]Kaisa Tornberg
- Acoustic Microstreaming and Augmentation of Gas Exchange by Oscillating Membrane towards Microfluidic Artificial Lung May 28, 2025
