RSC – Lab Chip latest articles- High-throughput label-free assessment of sperm DNA fragmentation index via intelligent morphological imaging February 12, 2026Lab Chip, 2026, Accepted ManuscriptDOI: 10.1039/D5LC01122A, PaperYan Jin, Yujie Zou, Yueyun Weng, Zhaoyi Ye, Xiaoyang Chen, Zhengwu Liu, TaiLang Yin, Sheng Liu, Yan Zhang, Cheng LeiInfertility has emerged as an increasingly serious global public health concern, affecting approximately one in six individuals of reproductive age worldwide, with male-factor infertility accounting for nearly half of all...The […]Yan Jin
- Critical Review: Point of Care Molecular Cancer Diagnostics February 10, 2026Lab Chip, 2026, Accepted ManuscriptDOI: 10.1039/D5LC01014D, Critical Review Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Seemesh Bhaskar, Saurabh Umrao, Hankeun Lee, Joseph Tibbs, Amanda Bacon, Skye Shepherd, Takhmina Ayupova, Fatma Uysal Ciloglu, Leyang Liu, Anqi Tan, Wang-Chien Chen, My Thi Tra Nguyen, Maria Grace Scannell, Ugur Aygun, Ugur […]Seemesh Bhaskar
- Polydiacetylene (PDA) Coated Paper-Based Fluorescence Sensor for the Detection and Quantification of Bisphenol February 10, 2026Lab Chip, 2026, Accepted ManuscriptDOI: 10.1039/D5LC00821B, CommunicationGayathri Loganathan, Shubham Gurav, Khaja Moinuddin Shaik, Pirangi Srikanth, Aman Bhardwaj, Sukhendu NandiBisphenol (BPA) is a common environmental contaminant found in water, food, packaging, and human biological samples, raising significant health concerns due to its endocrine-disrupting properties, particularly its interference with estrogen...The content of this RSS Feed (c) The […]Gayathri Loganathan
- A wearable 3D-printed hollow microneedle device for pressure-driven interstitial fluid collection and testing February 10, 2026Lab Chip, 2026, Advance ArticleDOI: 10.1039/D5LC00657K, PaperNedim Hacıosmanoğlu, Emre Ece, Fatih InciμHolloSense, a novel 3D printed hollow microneedle (MN) device with integrated suction and test ports for the extraction and testing skin interstitial fluid (ISF).To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed […]Nedim Hacıosmanoğlu
- Fast and precise magnetophoresis of superparamagnetic nanoparticles on a micro-magnetic substrate in a static liquid environment February 10, 2026Lab Chip, 2026, Accepted ManuscriptDOI: 10.1039/D5LC01072A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Elise Bou, Claudia De La Fuente, Etienne Orsini, Sarah Delshadi, Orphée CUGAT, Franz BruckertMicro-magnet arrays coupled with external rotating magnetic fields have been reported for the manipulation of individual superparamagnetic particles in stationary microfluidics, […]Elise Bou
- Muscle Regeneration on a Chip: Exercise-Induced Microtrauma and Optimal Mechanical Stimulation Regimen February 9, 2026Lab Chip, 2026, Accepted ManuscriptDOI: 10.1039/D5LC00513B, PaperHongze Yin, Juan Zhang, Jing Zhou, Huiying Yang, jiahao wang, Yue Wang, Na Liu, Tao YueSkeletal muscles, through their coordinated interaction with bones and joints, enable diverse human movements and are essential for maintaining normal physiological functions and overall health. However, the physiological state of...The content of this RSS […]Hongze Yin
- 20 years of microfluidic technology for advancing plant sciences February 6, 2026Lab Chip, 2026, Accepted ManuscriptDOI: 10.1039/D5LC01036E, Critical Review Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Louis D. Cohen, Eleonora Moratto, Claire Elizabeth StanleyUnderstanding how plants respond to dynamic and spatially variable stimuli is a key goal in plant sciences. Traditional imaging methods often involve a trade-off between environmental […]Louis D. Cohen
- A Smart 3D Microfluidic Tumor Spheroid-Vessel Co-Culture Model for Studying Exosomal HSP-Mediated Tumor Invasion and Angiogenesis February 4, 2026Lab Chip, 2026, Accepted ManuscriptDOI: 10.1039/D5LC00857C, Communication Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Sisi Zhou, Fanshu Shan, Yue Zhang, Yu Cao, Junhui Cen, Noritada Kaji, Songqin LiuBreast cancer is one of the most prevalent malignant tumors in women, primarily due to their metastasis and recurrence. Deciphering the […]Sisi Zhou
- Microfluidic NMR for Operando Monitoring of Drug-Induced Metabolic Fluxes in Liver Tissue Slices February 4, 2026Lab Chip, 2026, Accepted ManuscriptDOI: 10.1039/D5LC00819K, PaperSylwia Joanna Barker, Bishnubrata Patra, Manvendra Sharma, Annamarija Raic, Ruby E. H Karsten, Elisabeth Verpoorte, Marcel UtzMonitoring metabolism in living tissues with high temporal resolution and broad metabolite coverage remains a major challenge. We introduce the TISuMR platform, a microfluidic Lab-on-a-Chip platform that enables continuous, non-invasive...The content of this […]Sylwia Joanna Barker
- Nanofluidic-based electrochemical pump for remotely controlled, on-demand drug delivery February 3, 2026Lab Chip, 2026, Advance ArticleDOI: 10.1039/D5LC00708A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Marco M. Paci, Nicola Di Trani, Paolo Bolla, Fabiana Del Bono, Takuma Yoshikawa, Isaac Tichy, Patrick S. Stayton, Alessandro GrattoniA nanofluidic electrochemical pump uses in situ gas generation to modulate pressure and enable remotely […]Marco M. Paci
- Systematic characterization and mechanistic insights into ultrasonically actuated sharp-tip capillary droplet generation February 3, 2026Lab Chip, 2026, Advance ArticleDOI: 10.1039/D5LC00954E, PaperQi Zhang, Li Ran, Gang LiUltrasonically driven sharp-tip capillary generates droplets without chips or pumps. A three-stage pinch-off mechanism has been elucidated, enabling the production of programmable multi-volume droplet trains within a single stream.To cite this article before page numbers are assigned, use the DOI form of citation above.The […]Qi Zhang
- Correction: A tumor spheroid array chip for high-fidelity evaluation of liposomal drug delivery through the EPR effect February 3, 2026Lab Chip, 2026, Advance ArticleDOI: 10.1039/D6LC90011A, Correction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Yedam Lee, Sujin Kim, Hyeyeon Koh, Yeonwoo Park, Jung Y. Han, Jihoon KoTo cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) […]Yedam Lee
- Development of a 3D-printed microfluidic chip for retinal organoid–endothelial co-culture February 2, 2026Lab Chip, 2026, Advance ArticleDOI: 10.1039/D5LC00939A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Rodi Kado Abdalkader, Shigeru Kawakami, Yuuki Takashima, Takuya FujitaA fully 3D-printed microfluidic device enables direct co-culture of hiPSC-derived retinal organoids and endothelial cells.To cite this article before page numbers are assigned, use the DOI […]Rodi Kado Abdalkader
- Label-free assessment of a microfluidic vessel-on-chip model with visible-light optical tomography reveals structural changes in vascular networks January 30, 2026Lab Chip, 2026, Advance ArticleDOI: 10.1039/D5LC00927H, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Devin Veerman, Carlos Cuartas-Vélez, Tarek Gensheimer, Tomas van Dorp, Andries van der Meer, Nienke BosschaartOptical coherence tomography is a label-free imaging technique that can provide structural readouts in a vessel-on-chip.To cite this article before […]Devin Veerman
- Lab-on-a-chip for enzyme activity monitoring in industrial solid-state fermentation processes compatible with R2R fabrication January 30, 2026Lab Chip, 2026, Advance ArticleDOI: 10.1039/D5LC00528K, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Verónica Mora-Sanz, Alvaro Conde, Elisabeth Hengge, Conor O'Sullivan, Andoni Rodriguez, Caroline Hennigs, Maciej Skolimowski, Nastasia Okulova, Jan Kafka, Bernd Nidetzky, Ana Ayerdi, Matija Strbac, Martin Smolka, Goran Bijelic, Nerea BrizA disposable lab-on-a-chip fabricated by […]Verónica Mora-Sanz
- Lab-on-a-chip for biomarker detection: advances, practical applications, and future perspectives January 30, 2026Lab Chip, 2026, Advance ArticleDOI: 10.1039/D5LC00986C, Tutorial ReviewTianfeng Xu, Hao Bai, Jie Hu, Limei Zhang, Weihua Zhuang, Chang Zou, Yongchao Yao, Wenchuang (Walter) Hu, Jin HuangLab-on-a-chip (LoC) technology revolutionizes biomarker detection by integrating multiple analytical functions into a single, miniaturized platform, enabling efficient and versatile application across diverse scenarios.To cite this article before page numbers […]Tianfeng Xu
- MyeliMAP: a microfluidic-multielectrode array hybrid platform to investigate oligodendrocyte function in human iPSC derived brain-like networks January 29, 2026Lab Chip, 2026, Advance ArticleDOI: 10.1039/D5LC01062D, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Karan Ahuja, Blandine F. Clément, Giulia Amos, Joël Küchler, Keimpe Wierda, Yoke Chin Chai, Lieve Moons, Catherine VerfaillieMyeliMAP, a human iPSC-based myelination platform integrating microfluidics and high-density electrophysiology enables functional assessment of axonal conduction […]Karan Ahuja
- Controlling spatial structure in minimal microbial communities by sequential capillary assembly January 29, 2026Lab Chip, 2026, Advance ArticleDOI: 10.1039/D6LC00040A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Cameron Boggon, Jeremy P. H. Wong, Arpita Sahoo, Annelies S. Zinkernagel, Markus A. Seeger, Eleonora Secchi, Lucio IsaControlled patterning of microparticles with specific binding allows building two-species bacterial communities with defined spatial structures.To cite […]Cameron Boggon
- The evolution of nanopore measurements: from biological out-of-plane pores to plastic in-plane pores January 28, 2026Lab Chip, 2026, Advance ArticleDOI: 10.1039/D5LC00885A, Critical Review Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Khurshed Akabirov, Hanna Nguyen, Shakila Peli Thanthri, Sheila M. Barros, Maximillian Chibuike, Sunggook Park, Steven A. SoperA comprehensive review of in-plane and out-of-plane nanopore configurations for label-free single molecule detection is discussed herein. […]Khurshed Akabirov
- A dynamically cultured intestinal epithelial barrier model with metabolomics assessment for evaluating oxidative injury January 28, 2026Lab Chip, 2026, Advance ArticleDOI: 10.1039/D5LC01070E, PaperJiayi Yan, Jingyan Gao, Xinyi Jin, Jiacheng Cheng, Wentao Su, Chunqing Ai, Fanhua Kong, Shuang SongThis study developed a high-throughput intestinal organ-on-a-chip based on adhesive tape material and further established an intestinal oxidative damage model using this intestinal chip.To cite this article before page numbers are assigned, use the […]Jiayi Yan
- High-throughput label-free assessment of sperm DNA fragmentation index via intelligent morphological imaging February 12, 2026
