RSC – Lab Chip latest articles- Vascularized tumor-on-a-chip to investigate immunosuppression of CAR-T cells Tháng 4 17, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D4LC01089B, PaperRajul S Bains, Tara G Raju, Layla C Semaan, Anton Block, Yukiko Yamaguchi, Saul J Priceman, Steven George, Venktesh S ShirureChimeric Antigen Receptor (CAR)-T cell immunotherapy, effective in blood cancers, shows limited success in solid tumors, such as prostate, pancreatic, and brain cancers due, in part, to an immunosuppressive […]Rajul S Bains
- A high-throughput microfluidic platform for functional hiPSC-derived liver organoids with bile duct- and lobule- like structures Tháng 4 15, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00154D, PaperXiuxiu Zhang, Zixian Wang, Jianwei Chen, Tao XuHiPSC-derived organoids have attracted significant attention in stem cell research and regenerative medicine. However, obtaining functional organoids in sufficient quantities, consistent sizes, and reproducible formats remains a significant challenge. Here,...The content of this RSS Feed (c) The Royal Society of ChemistryXiuxiu Zhang
- Evaluating Migration and Cytotoxicity of Tissue-Resident and Conventional NK Cells in a 3D Microphysiological System Using Live-Cell Imaging Tháng 4 15, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D4LC01095G, PaperHyeri Choi, June Ho Shin, Hyeonsu Jo, John B. Sunwoo, Noo Li JeonNatural Killer (NK) cells are critical components of the immune response against cancer, recognized for their ability to target and eliminate malignant cells. Among NK cell subsets, tissue resident NK...The content of this RSS Feed (c) The […]Hyeri Choi
- Integrated Microfluidic Colorimetric Patch with Auto-Framing APP for Multiplex Temporal Detection of Ketone Bodies in Sweat Tháng 4 15, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00189G, PaperTianhao Xue, JiaNing Shen, Wanting Lin, Jiahui Zhou, Xiaofang Zhang, Jen-Tsai Liu, Ching-Jung Chen, Guixian ZhuKetone bodies are key products of fat metabolism, primarily consisting of acetoacetate (AcAc), β-hydroxybutyrate (BHB), and acetone (Acetone). Monitoring the concentration of ketone bodies in sweat can reflect the metabolic...The content of this RSS […]Tianhao Xue
- Evaluation of pre-osteoblastic cell line behaviors under low shear stress conditions Tháng 4 15, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D4LC00917G, PaperNae-Un Kang, Eun Chae Kim, Sang-Gi Yu, Hye Jin U, You Min Kim, Gwan Yong Baek, Young-Sam Cho, Hyung Woo KimThis study investigates the effects of low shear stress (0.01 Pa and 0.1 Pa) on pre-osteoblastic cell line behaviors using a specially designed shear stress generating microchannel system.To cite […]Nae-Un Kang
- Cancer-on-a-Chip for Precision Cancer Medicine Tháng 4 14, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D4LC01043D, Critical Review Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Lunan Liu, Huishu Wang, Ruiqi Chen, Yujing Song, William Wei, David Baek, Mahan Gillin, Katsuo Kurabayashi, Weiqiang ChenMany cancer therapies fail in clinical trials despite showing potent efficacy in preclinical studies. One of […]Lunan Liu
- Engineering Neuronal Networks in Granular Microgels to Innervate Bioprinted Cancer Organoids On-a-Chip Tháng 4 14, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00134J, PaperJacob Preston Fredrikson, Daniela M Roth, Jameson A Cosgrove, Gulsu Sener, Lily A Crow, Kazumi Eckenstein, Lillian Wu, Mahshid Hosseini, George Thomas, Sebnem Ece Eksi, Luiz E. BertassoniOrganoid models are invaluable for studying organ processes in vitro, offering an unprecedented ability to replicate organ function. Despite recent advancements that […]Jacob Preston Fredrikson
- Dual lateral flow assay using quantum nanobeads for quantitative detection of BDNF and TNF-α in tears Tháng 4 14, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D4LC01045K, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Yue Wu, Yubing Hu, Nan Jiang, Maria W. Georgi, Ali K. Yetisen, M. Francesca CordeiroA dual-test lateral flow assay (LFA) was developed to simultaneously detect TNF-α and BDNF in tear fluid, providing a practical […]Yue Wu
- Fluorophilic Boronic Acid Copolymer Surfactant for Stabilization of Complex Emulsion Droplets with Fluorinated Oil Tháng 4 14, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00309A, CommunicationZhang Wu, Brendan Deveney, Jörg G. Werner, Stefano Aime, David A. WeitzA fluorosurfactant is synthesized by the copolymerization of fluoroacrylate and boronic acid acrylamide monomers to stabilize fluorinated oil droplets. The copolymer surfactant couples with diols or polyols in adjacent aqueous...The content of this RSS Feed (c) The Royal […]Zhang Wu
- Calcite-functionalized microfluidic chip for pore scale investigation of biogeochemical interactions in porous media Tháng 4 10, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00105F, Communication Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Na Liu, Martin Anders FernøMicromodels are widely used to simulate subsurface reservoir environments for investigating multiphase flow and interactions within porous media. However, existing models often fail to accurately replicate the geochemical characteristics of...The […]Na Liu
- A Hybrid Dielectrophoretic Trap-Optical Tweezers Platform for Manipulating Microparticles in Aqueous Suspension Tháng 4 10, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D4LC00982G, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Carlos David González-Gómez, Jose García-Guirado, Romain Quidant, Emilio Ruiz-Reina, FELIX CARRIQUE FERNANDEZ, Raul A. Rica-AlarcónWe demonstrate that a set of microfabricated electrodes can be coupled to a commercial optical tweezers device, implementing a hybrid […]Carlos David González-Gómez
- Roll-to-roll fabrication of three-dimensional self-folding microstructures Tháng 4 10, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00120J, PaperTongyao Wu, Ali Mehrnezhad, Kidong ParkSelf-folding technology offers a promising alternative to conventional microfabrication techniques. It utilizes controlled and imbalanced stresses to transform specific patterns of flat materials into pre-determined three-dimensional (3D) structures for diverse...The content of this RSS Feed (c) The Royal Society of ChemistryTongyao Wu
- Microfluidic osmotic compression with operando meso-structure characterization using SAXS Tháng 4 9, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D4LC01087F, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Dimitri Radajewski, Pierre Roblin, Patrice Bacchin, Martine Meireles, Yannick HallezWe have developed a microfluidic chip for the osmotic compression of samples at the nanoliter scale, enabling the in situ and operando acquisition of structural […]Dimitri Radajewski
- A novel microfluidic self-perfusion chip (MSPC) for pumpless 3D cell, microtissue and organoid culture Tháng 4 9, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00030K, PaperGuohua Wu, Di Wu, Wenqi Hu, Qinrui Lu, Yusen Zhou, Jie Liu, Qijun Du, Zhi Luo, Haijie Hu, Hongwei Jiang, Bangchuan Hu, Shuqi WangThis study develops a self-perfusion microfluidic chip driven by evaporation that maintains cell culture without external pumps, enabling stable, long-term drug screening and toxicity testing for […]Guohua Wu
- Correction: Mechanical forces and enzymatic digestion act together to induce the remodeling of collagen fibrils in tumor microenvironment Tháng 4 8, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC90037A, Correction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Jiling Shi, Aihua Jing, Qinan Yin, Xuewei Zheng, Zhigang Hu, Xibin Jiao, Yaomin Fan, Xiangyang Zu, Jinghua Li, Yanping Liu, Jiayu Zhai, Xiucheng Li, Kena SongTo cite this article before page numbers are assigned, […]Jiling Shi
- Integration of multi-coils shim and RF microstrip coils for high-resolution microfluidic nuclear magnetic resonance detection Tháng 4 8, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00209E, PaperHuijun Sun, Xin Xie, Xinchang Wang, Yaohong Wang, Zhenggang Li, Junyao Xie, Kaiwen Yao, Jinglong Guan, ying he, Zhong ChenThe integration of nuclear magnetic resonance (NMR) and microfluidic technology provides an excellent detection method for detecting nanoscale micro-samples and analysing intermediates during in-situ reaction processes. However, the non-cylindrical symmetric...The […]Huijun Sun
- Advancements in microfluidic technology for rapid bacterial detection and inflammation-driven diseases Tháng 4 8, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D4LC00795F, Critical Review Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jing Zhang, Yatian Fu, Ching Yin Fong, Haojun Hua, Wei Li, Bee Luan KhooMicrofluidic platforms have gained significant attention for their role in rapid bacterial detection and the study of inflammatory diseases.To cite […]Jing Zhang
- Light-based 3D printing and post-treatments of moulds for PDMS soft lithography Tháng 4 6, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D4LC00836G, Critical Review Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Bastien VenzacThe fabrication of moulds by 3D printing for PDMS replication and their post-treatments to avoid PDMS curing inhibition are reviewed.To cite this article before page numbers are assigned, use the DOI form […]Bastien Venzac
- Chiral organic–inorganic hybrid perovskites synthesized using an acoustofluidic closed system Tháng 4 4, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D4LC01073F, PaperTao Zhou, Yan Yu, Haonan Zhang, Chong Li, Ran Tao, Fujian Ren, Chen Fu, Jingting Luo, Yongqing FuA closed surface acoustic wave microcentrifugation (SAWM) system was employed to facilitate the deposition of high-quality organic–inorganic hybrid perovskite (OIHP) thin films.To cite this article before page numbers are assigned, use the […]Tao Zhou
- On-chip colorimetric assay for determining serum lithium concentration from whole blood Tháng 4 3, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00044K, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Carl Olsson, Janosch Hauser, Federico Ribet, Fredrik Wikström, André Görgens, Olof Beck, Martin Schalling, Lena Backlund, Niclas RoxhedWe present a device able to measure the serum lithium concentration directly from capillary finger-prick blood. The […]Carl Olsson
- Vascularized tumor-on-a-chip to investigate immunosuppression of CAR-T cells Tháng 4 17, 2025
