RSC – Lab Chip latest articles
- Analytical validation of the DroXpert S6 system for diagnosis of chronic myelocytic leukemia Tháng Năm 2, 2024Lab Chip, 2024, Accepted ManuscriptDOI: 10.1039/D4LC00175C, PaperWenjia Wei, Shujun Li, ying Zhang, Simin Deng, Qun He, Xielan Zhao, Yajing Xu, Linfen Yu, Junwei Ye, weiwei Zhao, Zhiping JiangDigital PCR is a powerful method for absolute nucleic acid quantification and is widely used in the absolute quantification of viral copy numbers, tumor marker detection, and prenatal […]Wenjia Wei
- Concentration-Polarization Electroosmosis for particle fractionation Tháng Năm 2, 2024Lab Chip, 2024, Accepted ManuscriptDOI: 10.1039/D4LC00081A, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Raul Fernandez-Mateo, Pablo Garcia-Sanchez, Antonio Ramos, Hywel MorganConcentration-Polarization Electroosmosis (CPEO) refers to steady-state electroosmotic flows around charged dielectric micro-particles induced by low-frequency AC electric fields. Recently, these flows were shown to cause repulsion of […]Raul Fernandez-Mateo
- Bridging barriers: advances and challenges in modeling biological barriers and measuring barrier integrity in organ-on-chip systems Tháng Tư 30, 2024Lab Chip, 2024, Advance ArticleDOI: 10.1039/D3LC01027A, Critical ReviewAlisa Ugodnikov, Henrik Persson, Craig A. SimmonsBiological barriers play key roles in homeostasis, disease physiology and drug delivery, highlighting a need for representative in vitro tools. We discuss advances and challenges in modeling and measuring barrier integrity in organ-on-chip systems.To cite this article before page numbers are assigned, […]Alisa Ugodnikov
- Antigen density and applied force control enrichment of nanobody-expressing yeast cells in microfluidics Tháng Tư 28, 2024Lab Chip, 2024, Accepted ManuscriptDOI: 10.1039/D4LC00011K, PaperMerlin Sanicas, Remy Torro, Laurent Limozin, Patrick ChamesIn vitro display technologies such as yeast display have been instrumental in developing the selection of new antibodies, antibody fragments or nanobodies that bind to a specific target, with affinity...The content of this RSS Feed (c) The Royal Society of ChemistryMerlin Sanicas
- On the compatibility of single-cell microcarriers (nanovials) with microfluidic impedance cytometry Tháng Tư 28, 2024Lab Chip, 2024, Accepted ManuscriptDOI: 10.1039/D4LC00002A, PaperCristian Brandi, Adele De Ninno, Filippo Ruggiero, Emanuele Limiti, Franca Abbruzzese, Marcella Trombetta, Alberto Rainer, Paolo Bisegna, Federica CaselliWe investigate for the first time the compatibility of nanovials with microfluidic impedance cytometry (MIC). Nanovials are suspendable crescent-shaped single-cell microcarriers that enable specific cell adhesion, the creation of compartments...The content […]Cristian Brandi
- Revolutionizing sample preparation: a novel autonomous microfluidic platform for serial dilution Tháng Tư 24, 2024Lab Chip, 2024, Advance ArticleDOI: 10.1039/D4LC00195H, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Dries Vloemans, Alexander Pieters, Francesco Dal Dosso, Jeroen LammertynA standalone and fully automated microfluidic platform for the stepwise preparation of serial dilutions without the need for any active elements.To cite this article before page […]Dries Vloemans
- Microfluidic confined acoustic streaming vortex for liposome synthesis Tháng Tư 24, 2024Lab Chip, 2024, Advance ArticleDOI: 10.1039/D4LC00184B, PaperHuihui Xu, Zhaoxun Wang, Wei Wei, Tiechuan Li, Xuexin DuanAn acoustofluidic platform for controllable size liposome synthesis using microfluidic confined acoustic streaming vortex. It combines the features of both hydrodynamic flow focusing and rapid micro-mixing.To cite this article before page numbers are assigned, use the DOI form of citation […]Huihui Xu
- Chip-integrated non-mechanical microfluidic pump driven by electrowetting on dielectrics Tháng Tư 23, 2024Lab Chip, 2024, Advance ArticleDOI: 10.1039/D4LC00178H, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Sebastian Bohm, Hai Binh Phi, Lars Dittrich, Erich RungeA robust chip-integrated EWOD-driven micropump is presented that generates microscopically usable continuous flow rates and pressures without any moving parts.To cite this article before page numbers […]Sebastian Bohm
- Drug testing of monodisperse arrays of live microdissected tumors using a valved multiwell microfluidic platform Tháng Tư 22, 2024Lab Chip, 2024, Advance ArticleDOI: 10.1039/D4LC00016A, PaperEthan J. Lockhart, Lisa F. Horowitz, Adán Rodríguez, Songli Zhu, Tran Nguyen, Mehdi Mehrabi, Taranjit S. Gujral, Albert FolchA microfluidic platform was developed that hydrodynamically traps microdissected cuboids for selective drug treatments and isolates conditions with thermoplastic valves.To cite this article before page numbers are assigned, use the DOI […]Ethan J. Lockhart
- Microfluidic approach to correlate C. elegans neuronal functional aging and underlying changes of gene expression in mechanosensation Tháng Tư 22, 2024Lab Chip, 2024, Advance ArticleDOI: 10.1039/D3LC01080E, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jason Wan, Jimmy L. Ding, Hang LuThis work presents a framework integrating microfluidic technologies to uncover aging-related insights. This platform allows for measuring physiological function and its associated gene expression through the aging process […]Jason Wan
- Correction: Direct laser writing-enabled 3D printing strategies for microfluidic applications Tháng Tư 21, 2024Lab Chip, 2024, 24,2590-2590DOI: 10.1039/D4LC90040E, Correction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Olivia M. Young, Xin Xu, Sunandita Sarker, Ryan D. SocholThe content of this RSS Feed (c) The Royal Society of ChemistryOlivia M. Young
- Automated Dynamic Inlet Microfluidics System: 3D Printer Adaptation for Cost-Effective, Low Volume, On-Demand Multi-Analyte Droplet Generator Tháng Tư 21, 2024Lab Chip, 2024, Accepted ManuscriptDOI: 10.1039/D4LC00075G, PaperAbdul Basit Zia, Justin Farrell, Ian G. FouldsThe paper demonstrates an adaptation of a 3D printer (Prusa Mini+) with novel modules to develop a droplet generation system that generates combinatorial droplets from a standard 96 well plate....The content of this RSS Feed (c) The Royal Society of ChemistryAbdul Basit Zia
- Reproducible generation of human liver organoids (HLOs) on a pillar plate platform via microarray 3D bioprinting Tháng Tư 19, 2024Lab Chip, 2024, Advance ArticleDOI: 10.1039/D4LC00149D, PaperSunil Shrestha, Vinod Kumar Reddy Lekkala, Prabha Acharya, Soo-Yeon Kang, Manav Goud Vanga, Moo-Yeal LeeWe developed microarray 3D bioprinting technology and associated pillar/deep well plates that allow high-throughput, miniature, and uniform culture of human liver organoids (HLOs) from bioprinted foregut cells and facilitate in situ assessments.To cite this article […]Sunil Shrestha
- Advanced sequencing-based high-throughput and long-read single-cell transcriptome analysis Tháng Tư 18, 2024Lab Chip, 2024, Advance ArticleDOI: 10.1039/D4LC00105B, Critical ReviewShanqing Huang, Weixiong Shi, Shiyu Li, Qian Fan, Chaoyong Yang, Jiao Cao, Lingling WuIn this review, we provide a broad introduction to advanced high-throughput and long-read single-cell transcriptome analysis using next-generation sequencing and third-generation sequencing platforms.To cite this article before page numbers are assigned, use the DOI form […]Shanqing Huang
- High-resolution low-cost LCD 3D printing for microfluidics and organ-on-a-chip devices Tháng Tư 18, 2024Lab Chip, 2024, Advance ArticleDOI: 10.1039/D3LC01125A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Houda Shafique, Vahid Karamzadeh, Geunyong Kim, Molly L. Shen, Yonatan Morocz, Ahmad Sohrabi-Kashani, David JunckerMicrofluidic and organ-on-a-chip device fabrication via low-cost LCD photopolymerization 3D printing using a custom photoink for high-resolution, fast, and throughput […]Houda Shafique
- Microflow sensing and control using an in-channel birefringent biomembrane Tháng Tư 18, 2024Lab Chip, 2024, Advance ArticleDOI: 10.1039/D3LC00985H, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Nan Jia, Tianyang Deng, Charles Larouche, Tigran Galstian, André Bégin-Drolet, Jesse GreenerWe report a flow sensitive birefringent in-channel chitosan micromembrane. Using a simple cross-polarizer and a calibration curve, the membrane functions as a flow […]Nan Jia
- A microfluidic microalgae detection system for cellular physiological response based on an object detection algorithm Tháng Tư 17, 2024Lab Chip, 2024, Advance ArticleDOI: 10.1039/D3LC00941F, PaperShizheng Zhou, Tianhui Chen, Edgar S. Fu, Teng Zhou, Liuyong Shi, Hong YanWe present a label-free, multi-scale, sheath-less microfluidic microalgae detection system enabled with an improved deep learning algorithm, called MD-YOLO, for tiny cell classification and physiological status monitoring.To cite this article before page numbers are assigned, use the […]Shizheng Zhou
- Development of a microfluidic device to enrich and detect zearalenone in food using quantum dot-embedded molecularly imprinted polymers Tháng Tư 16, 2024Lab Chip, 2024, Advance ArticleDOI: 10.1039/D4LC00193A, PaperMarti Z. Hua, Shenmiao Li, M. S. Roopesh, Xiaonan LuA QD-MIP based microfluidic device to detect mycotoxin in food.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of ChemistryMarti Z. Hua
- Multiplex nanozymatic biosensing of Salmonella on a finger-actuated microfluidic chip Tháng Tư 15, 2024Lab Chip, 2024, Advance ArticleDOI: 10.1039/D4LC00291A, PaperNana Jin, Fan Jiang, Fengzhen Yang, Ying Ding, Ming Liao, Yanbin Li, Jianhan LinA colorimetric biosensor was elaboratively designed for fast, sensitive and multiplex bacterial detection on a single microfluidic chip.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this […]Nana Jin
- Portable platform for leukocyte extraction from blood using sheath-free microfluidic DLD Tháng Tư 14, 2024Lab Chip, 2024, 24,2575-2589DOI: 10.1039/D4LC00132J, PaperOriana G. Chavez-Pineda, Roberto Rodriguez-Moncayo, Alan M. Gonzalez-Suarez, Pablo E. Guevara-Pantoja, Jose L. Maravillas-Montero, Jose L. Garcia-CorderoA microfluidic platform isolates leukocytes from blood efficiently, offering diagnostic and immunotherapeutic potential. Enhanced by a handheld pressure controller, it enables near-patient testing and integration with downstream assays.The content of this RSS Feed (c) […]Oriana G. Chavez-Pineda
- Analytical validation of the DroXpert S6 system for diagnosis of chronic myelocytic leukemia Tháng Năm 2, 2024