RSC – Lab Chip latest articles
- Reproducible generation of human liver organoids (HLOs) on a pillar plate platform via microarray 3D bioprinting April 19, 2024Lab Chip, 2024, Accepted ManuscriptDOI: 10.1039/D4LC00149D, PaperSunil Shrestha, Vinod Kumar Reddy Lekkala, Prabha Acharya, Soo-Yeon Kang, Manav Goud Vanga, Moo-Yeal LeeHuman liver organoids (HLOs) hold significant potential for recapitulating the architecture and function of liver tissues in vivo. However, conventional culture methos of HLOs, forming Matrigel domes in 6-/24-well plates,...The content of this RSS Feed […]Sunil Shrestha
- High-resolution low-cost LCD 3D printing for microfluidic and organ-on-a-chip devices April 18, 2024Lab Chip, 2024, Accepted ManuscriptDOI: 10.1039/D3LC01125A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Houda Shafique, Vahid Karamzadeh, Geunyong Kim, Molly L. Shen, Yonatan Morocz, Ahmad Sohrabi Kashani, David JunckerThe fabrication of microfluidic devices has progressed from cleanroom manufacturing to replica molding in polymers, and more recently to […]Houda Shafique
- Advanced sequencing-based high-throughput and long-read single-cell transcriptome analysis April 18, 2024Lab Chip, 2024, Accepted ManuscriptDOI: 10.1039/D4LC00105B, Critical ReviewShanqing Huang, Weixiong Shi, Shiyu Li, Qian Fan, Chaoyong Yang, Jiao Cao, Lingling WuCells are the fundamental building blocks of living systems, exhibiting significant heterogeneity. The transcriptome connects the cellular genotype and phenotype, and profiling single-cell transcriptome is critical for uncovering distinct cell...The content of this RSS Feed […]Shanqing Huang
- Microflow sensing and control using an in-channel birefringent biomembrane April 18, 2024Lab Chip, 2024, Advance ArticleDOI: 10.1039/D3LC00985H, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Nan Jia, Tianyang Deng, Charles Larouche, Tigran Galstian, André Bégin-Drolet, Jesse GreenerWe report a flow sensitive birefringent in-channel chitosan micromembrane. Using a simple cross-polarizer and a calibration curve, the membrane functions as a flow […]Nan Jia
- A microfluidic microalgae detection system for cellular physiological response based on object detection algorithm April 17, 2024Lab Chip, 2024, Accepted ManuscriptDOI: 10.1039/D3LC00941F, PaperShizheng Zhou, Tianhui Chen, Edgar S. Fu, Liuyong Shi, Teng Zhou, Hong YANThe composition of species and the physiological status of microalgal cells serve as significant indicators for monitoring marine environments. Symbiotic with corals, Symbiodiniacea are more sensitive to the environmental response....The content of this RSS Feed (c) The […]Shizheng Zhou
- Development of a microfluidic device to enrich and detect zearalenone in food using quantum dot-embedded molecularly imprinted polymers April 16, 2024Lab Chip, 2024, Accepted ManuscriptDOI: 10.1039/D4LC00193A, PaperMarti Hua, Shenmiao Li, Roopesh Syamaladevi, Xiaonan LuMycotoxins are secondary metabolites of certain moulds, prevalent in 60-80% of food crops and many processed products but challenging to eliminate. Consuming mycotoxin-contaminated food and feed can lead to various...The content of this RSS Feed (c) The Royal Society of ChemistryMarti Hua
- Multiplex nanozymatic biosensing of Salmonella on a finger-actuated microfluidic chip April 15, 2024Lab Chip, 2024, Accepted ManuscriptDOI: 10.1039/D4LC00291A, PaperNana Jin, Fan Jiang, Fengzhen Yang, Ying Ding, Ming Liao, Yanbin Li, Jianhan LinA colorimetric biosensor was elaboratively designed for fast, sensitive and multiplex bacterial detection on a single microfluidic chip using immune magnetic nanobeads for specific bacterial separation, immune gold@platinum palladium nanoparticles...The content of this RSS Feed (c) […]Nana Jin
- Rocking- and diffusion-based culture of tumor spheroids-on-a-chip April 14, 2024Lab Chip, 2024, Advance ArticleDOI: 10.1039/D3LC01116J, PaperDuomei Tian, Zheng Mao, Li Wang, Xiaochen Huang, Wei Wang, Haoyue Luo, Juan Peng, Yong ChenTumor spheroids are cultured in hydrogel microwells with a gravity driven medium flow underneath the membrane on-a-chip. The rocking system is pumpless, powered with a rechargeable battery, and programmable with a built-in microprocess.To cite […]Duomei Tian
- Portable platform for leukocyte extraction from blood using sheath-free microfluidic DLD April 14, 2024Lab Chip, 2024, Accepted ManuscriptDOI: 10.1039/D4LC00132J, PaperOriana Gerallin Chavez-Pineda, Roberto Rodriguez-Moncayo, Alan Mauricio Gonzalez-Suarez, Pablo Enrique Guevara-Pantoja, Jose Luis Maravillas-Montero, Jose L. Garcia-CorderoLeukocyte count is routinely performed for diagnostic purposes and is rapidly emerging as a significant biomarker for a wide array of diseases. Additionally, leukocytes have demonstrated considerable promise in novel...The content of this […]Oriana Gerallin Chavez-Pineda
- Operando scanning electron microscopy platform for in situ imaging of fluid evolution in nanoporous shale April 11, 2024Lab Chip, 2024, Accepted ManuscriptDOI: 10.1039/D3LC01066J, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Artur Davletshin, Wen SongFluid-solid interactions in nanoporous materials underlie processes fundamental to nature and the engineered environment, including the thermochemical transformation of argillaceous materials during high-level nuclear waste disposal. Operando fluid-solid resolution at...The content […]Artur Davletshin
- A Paper-based Dual Functional Biosensor for Safe and User-Friendly Point-of-Care Urine Analysis April 11, 2024Lab Chip, 2024, Accepted ManuscriptDOI: 10.1039/D4LC00163J, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Yujia Li, Yingqi Kong, Yubing Hu, Yixuan Li, Rica Asrosa, Wenyu Zhang, Buddha Deka Boruah, Ali Kemal Yetisen, Andrew Davenport, Tung-Chun Lee, Bing LiSafe, accurate, and reliable analysis of urinary biomarkers is clinically important […]Yujia Li
- Screening for Urothelial Carcinoma Cells in Urine Based on Digital Holographic Flow Cytometry through Machine Learning and Deep Learning Method April 11, 2024Lab Chip, 2024, Accepted ManuscriptDOI: 10.1039/D3LC00854A, PaperLu Xin, Xi Xiao, Wen Xiao, Ran Peng, Hao Wang, Feng PanThe incidence of urothelial carcinoma continue to rise annually, particularly among the elderly. Prompt diagnosis and treatment can significantly enhance patient survival and quality of life. Urine cytology remains a...The content of this RSS Feed (c) The Royal […]Lu Xin
- Versatile hybrid technique for passive straight micromixer manufacturing by combining pulsed laser ablation, stereolithographic 3D printing and computational fluid dynamics April 10, 2024Lab Chip, 2024, Accepted ManuscriptDOI: 10.1039/D4LC00009A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Bastián Carnero, Yago Radziunas-Salinas, Bruno Kotksa Rodiño-Janeiro, Sylvana Varela Ballesta, María Teresa Teresa Flores-AriasThere is a need to develop new and versatile fabrication methods to obtain an efficient mixing of fluids in microfluidic channels […]Bastián Carnero
- A point-of-care testing platform for on-site identification of genetically modified crops April 9, 2024Lab Chip, 2024, Accepted ManuscriptDOI: 10.1039/D4LC00040D, PaperYangyang Wang, Furui Yang, Yingyi Fu, Xin He, Haowei Tian, Lili Yang, Mengxi Wu, Jijuan Cao, Junshan LiuGenetically modified (GM) food is still highly controversial nowadays. Due to the disparate policies and attitudes worldwide, demands for a rapid, cost-effective and user-friendly GM crops identification method are increasingly...The content of […]Yangyang Wang
- Detection and Identification of Single Ribonucleotide Monophosphates using a Dual In-Plane Nanopore Sensor Made from a Thermoplastic via Replication April 9, 2024Lab Chip, 2024, Accepted ManuscriptDOI: 10.1039/D3LC01062G, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Steven A. Soper, Chathurika Rathnayaka, Indu Chandrasoma, Junseo Choi, Katie Childers, Maximillian Chibuike, Khurshed Akabirov, Farhad Shiri, Adam R Hall, Collin J McKinney, Matthew David Verber, Sunggook ParkWe report the generation of ~8 nm […]Steven A. Soper
- Dielectrophoretic characterization and selection of non-spherical flagellate algae in parallel channels with right-angle bipolar electrodes April 7, 2024Lab Chip, 2024, Advance ArticleDOI: 10.1039/D4LC00165F, PaperXiaoming Chen, Shun Liu, Mo Shen, Jishun Shi, Chungang Wu, Zhipeng Song, Yong ZhaoWe develop a microfluidic device with closed right-angle bipolar electrodes to realize dielectrophoretic characterization and selection of non-spherical flagellate algae.To cite this article before page numbers are assigned, use the DOI form of citation above.The content […]Xiaoming Chen
- Microfluidic Particle Counter Visualizing Mucosal Antibody Levels against SARS-CoV-2 in the Upper Respiratory Tract for Rapid Evaluation of Immune Protection April 7, 2024Lab Chip, 2024, Accepted ManuscriptDOI: 10.1039/D4LC00118D, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jiaheng Li, Lok Ting CHU, Hogi Hartanto, Guihuan Guo, Lu LIU, Jianpeng WU, Minghui Wu, Chenyu Cui, Gaobo Wang, Wengang LIU, Hoi Kwan Kwong, Siying WU, Ting-Hsuan ChenMucosal antibodies at the upper respiratory tract […]Jiaheng Li
- Study on the hemodynamic effects of different pulsatile working modes of a rotary blood pump using a microfluidic platform that realizes in vitro cell culture effectively April 4, 2024Lab Chip, 2024, Advance ArticleDOI: 10.1039/D4LC00159A, PaperLixue Liang, Xueying Wang, Dong Chen, Palaniappan Sethu, Guruprasad A. Giridharan, Yanxia Wang, Yu Wang, Kai-Rong QinThe best pulsation frequency mode of the RBP would be one that changes every 2–3 times of the cardiac cycle. The proposed in vitro microfluidic model could provide an effective platform to select […]Lixue Liang
- Piezoelectric and microfluidic tuning of an infrared cavity for vibrational polariton studies April 4, 2024Lab Chip, 2024, Advance ArticleDOI: 10.1039/D3LC01101A, PaperWei Wang, Jaime de la Fuente Diez, Nicolas Delsuc, Juan Peng, Riccardo Spezia, Rodolphe Vuilleumier, Yong ChenA new method uses piezoelectric and microfluidic tuning to study vibrational polaritons in liquids under flow. This enables modifying cavity length adjustments and flexibility in experimental setups.To cite this article before page numbers […]Wei Wang
- Spatially controlled diffusion range of tumor-associated angiogenic factors to develop a tumor model using a microfluidic resistive circuit April 4, 2024Lab Chip, 2024, Advance ArticleDOI: 10.1039/D3LC00891F, PaperYu-Hsiang Hsu, Wen-Chih Yang, Yi-Ting Chen, Che-Yu Lin, Chiou-Fong Yang, Wei-Wen Liu, Subhashree Shivani, Pai-Chi LiThe DC-MPS device uses a velocity V-clamp to create a partition with a steep concentration gradient for simultaneously developing vasculogenic vessels and a tumor. It enables vessel–tumor interaction to develop a tumor model with […]Yu-Hsiang Hsu
- Reproducible generation of human liver organoids (HLOs) on a pillar plate platform via microarray 3D bioprinting April 19, 2024