RSC – Org. Biomol. Chem. latest articles- Synthesis of Quinoxaline Derivatives via Aromatic Nucleophilic Substitution of Hydrogen December 8, 2022Org. Biomol. Chem., 2022, Accepted ManuscriptDOI: 10.1039/D2OB02016E, PaperAleksandra Zasada, Jakub Brześkiewicz, Damian Antoniak, Małgorzata Bechcicka, Rafał Loska, Mieczysław MąkoszaElectrophilic nature of quinoxaline has been explored in the vicarious nucleophilic substitution of hydrogen (VNS) with various carbanions as nucleophiles, in the attempt to develop a general method of functionalizing...The content of this RSS Feed (c) The […]Aleksandra Zasada
- Deazaflavin cofactor boosts earthworms Henlea bioluminescence December 8, 2022Org. Biomol. Chem., 2022, Accepted ManuscriptDOI: 10.1039/D2OB01946A, PaperValentin Petushkov, Matvey V. Vavilov, Igor Ivanov, Rustam H, Ziganshin, Natalia S. Rodionova, Ilia V Yampolsky, Aleksandra S Tsarkova, Maxim A DubinnyiBioluminescence of Siberian earthworms Henlea sp. was shown to be enhanced by two low molecular weight activators, termed ActH and ActS, found in the hot extracts. The […]Valentin Petushkov
- Chiral Phosphoric Acid-Catalyzed Enantioselective aza-Friedel–Crafts Reaction of Naphthols and Electron-Rich Phenols with 2-Aryl-3H-indol-3-ones December 8, 2022Org. Biomol. Chem., 2022, Accepted ManuscriptDOI: 10.1039/D2OB02179J, CommunicationTao Ma, Yonghui He, Xiu-Xiu Qiao, Chang-Peng Zou, Xi-Xi Wu, Ganpeng Li, Xiao-Jing ZhaoThe enantioselective aza-Friedel–Crafts reaction is one of the most straightforward and efficient strategies for constructing a new carbon-carbon bond bearing quaternary stereocenter in organic synthesis, but the catalytic asymmetric aza-...The content of this RSS Feed […]Tao Ma
- Ni-catalyzed C−F activation to construct C−P bond with P−P(O) and P(O)OR mediation December 8, 2022Org. Biomol. Chem., 2022, Accepted ManuscriptDOI: 10.1039/D2OB02047E, CommunicationJia Yang, Lei Fan, chen chen, Mingyue Wang, Bingqian Sun, Shuai Wang, Hong Zhong, Yongbo ZhouHere we developed an efficient Ni-catalyzed C−F bond phosphorylation of aryl fluorides via the crucial intermediates of P−P(O) and P(O)OR. The P−P(O) mediated organophosphorus generation is observed for active aryl...The content of this […]Jia Yang
- B(C6F5)3-catalyzed metal-free hydrogenation of 2-oxazolones December 8, 2022Org. Biomol. Chem., 2022, Accepted ManuscriptDOI: 10.1039/D2OB01950G, CommunicationGuangyu Cui, Xiangqing Feng, Haifeng DuA first metal-free hydrogenation of 2-oxazolones was successfully realized by using 10 mol % of B(C6F5)3 as a catalyst, giving a variety of 2-oxazolidinones in 70–98% yields. An enamine to...The content of this RSS Feed (c) The Royal Society of ChemistryGuangyu Cui
- Synthesis of mono-nitroxides and of bis-nitroxides with varying electronic through-bond communication December 8, 2022Org. Biomol. Chem., 2022, Accepted ManuscriptDOI: 10.1039/D2OB01863B, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Angeliki Giannoulis, Katrin Ackermann, Alexey V. Bogdanov, David Bradford Cordes, Catherine Higgins, Joshua Ward, Alexandra Slawin, James E Taylor, Bela E BodeNitroxides are a unique class of persistent radicals finding a wide range […]Angeliki Giannoulis
- Selective Access to Fused Tetrahydroquinolines via a Copper-Catalysed Oxidative Three-Component Annulation Reaction December 7, 2022Org. Biomol. Chem., 2022, Accepted ManuscriptDOI: 10.1039/D2OB02066A, PaperPeng Duan, Jialu Sun, Zhibo Zhu, Min ZhangVia a copper-catalyzed three-component annulation reaction, we herein report a new method for direct and syn-selective construction of cyclic ether-fused tetrahydroquinolines from readily available N-monosubstituted anilines, saturated five or six-membered...The content of this RSS Feed (c) The Royal Society of ChemistryPeng Duan
- Hydrogen bond templated synthesis of catenanes and rotaxanes from a single isophthalic acid derivative December 7, 2022Org. Biomol. Chem., 2022, Accepted ManuscriptDOI: 10.1039/D2OB02019J, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.SEAN Richard BARLOW, Geoffrey Akien, Nicholas Henley EvansHydrogen bond templated [2]catenanes and [2]rotaxanes have been synthesized using azide precursors derived from a single isophthalic acid derivative precursor. The interlocked molecules were prepared using […]SEAN Richard BARLOW
- Gold-catalyzed Synthesis of Unsymmetrical Dithioacetals December 7, 2022Org. Biomol. Chem., 2022, Accepted ManuscriptDOI: 10.1039/D2OB01737G, PaperCheol-Min Park, Murugesh V, Bokyeong RyouA gold-catalyzed protocol for the synthesis of unsymmetrically substituted dithioacetals is described. Both activated and unactivated vinyl sulfides undergo hydrothiolation with thiols bearing both electron donating and withdrawing groups in...The content of this RSS Feed (c) The Royal Society of ChemistryCheol-Min Park
- Visible-light induced three-component reaction of α-aminobutyronitrile synthesis by C-C bond formation using quantum dots as photocatalyst December 6, 2022Org. Biomol. Chem., 2022, Accepted ManuscriptDOI: 10.1039/D2OB01797K, PaperYu-Yun Yin, Xiao-Rui Liu, Jia-Hui Jin, Zhi-Ming Li, Yong-miao Shen, Jianhai Zhou, Xiaogang PengWe describe a three-component reaction of malononitrile, benzaldehyde and N,N-dimethylaniline using aluminium doped CdSeS/CdZnSeS(Al)/ZnS quantum dots (QDs) as visible light catalyst to synthesize α-aminobutyrilitriles under room temperature and mild conditions....The content of this RSS Feed […]Yu-Yun Yin
- Munronin V with 7/7/6 Tricarbocyclic Framework from Munronia henryi Harms Inhibit Tau Pathology via Activating Autophagy December 6, 2022Org. Biomol. Chem., 2022, Accepted ManuscriptDOI: 10.1039/D2OB01965E, CommunicationYing Yan, Xiao-Qian Ran, Dan Wang, Xiong Zhang, Mingyou Peng, Xiaoyan Yan, Lei Tang, Hong Liang, Xu-Jie Qin, Yingtong Di, Rongcan Luo, Xiaojiang Hao, Yong-Gang YaoMunronin V (1), isolated from Munronia henryi Harms, is the first example of unprecedented 7/7/6 tricarbocyclic framework featuring an unusual ring A,B-seco-limonoid. The […]Ying Yan
- -Carbonyl Sulfoxonium Ylides in Transition Metal Catalyzed C-H Activation: A Safe Carbene Precursor and A Weak Directing Group December 6, 2022Org. Biomol. Chem., 2022, Accepted ManuscriptDOI: 10.1039/D2OB01835G, Review ArticleChandra Volla, Anurag Singh, Shreemoyee KumarTransition metal-catalyzed cross-coupling of sp2C-H bonds with diazo compounds via carbene migratory insertion represents an efficient strategy for the construction of C-C and C-heteroatom bonds in organic synthesis. Despite the...The content of this RSS Feed (c) The Royal Society of ChemistryChandra Volla
- Selective Oxidative β-C–H Bond Sulfenylation of Tetrahydroisoquinolines with Elemental Sulfur December 6, 2022Org. Biomol. Chem., 2022, Accepted ManuscriptDOI: 10.1039/D2OB01976K, PaperTao Guo, Lei Bi, Lu Shen, Quanhong Wei, Congjun Zhu, Panke Zhang, Yun-Hui ZhaoIn this article, a convenient and efficient KIO3-promoted oxidative sulfenylation at the β-position of N‑heterocycles and subsequent aromatization in the presence of elemental S8 is presented. The reaction proceeds with...The content of this RSS Feed […]Tao Guo
- Quantification of the hydride donor abilities of NADH, NADPH, and BH3CN− in water December 6, 2022Org. Biomol. Chem., 2023, Advance ArticleDOI: 10.1039/D2OB02041F, Communication Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Robert J. Mayer, Joseph MoranDespite their structural differences, the hydride donors BH3CN−, NADH, and NADPH were found to feature very similar kinetic hydride donor abilities in aqueous solution.To cite this article before page […]Robert J. Mayer
- Enhanced Molecular Binding Affinity toward Aromatic Dications by Anthracene-Derived Crown Ethers in Water December 6, 2022Org. Biomol. Chem., 2022, Accepted ManuscriptDOI: 10.1039/D2OB02010F, PaperJia-Liang Zhou, Yan-Hong Li, Ying-Ming Zhang, Ling Chen, Yu LiuThe pursuit of high molecular binding affinity using conventional crown ethers in water remains a challenging task in the field of supramolecular chemistry and may hold great promise in the...The content of this RSS Feed (c) The Royal Society […]Jia-Liang Zhou
- Synthetic Application of Chalcogenonium Salts: Beyond Sulfonium December 6, 2022Org. Biomol. Chem., 2022, Accepted ManuscriptDOI: 10.1039/D2OB01822E, Review ArticleAlix Bastidas Ángel, Philipe Campos, Eduardo E AlbertoThe application of chalcogenonium salts in organic synthesis has grown enormously in the past decades since the discovery of the methyltransferase enzyme cofactor S-adenosyl-L-methionine (SAM), featuring a sulfonium center as...The content of this RSS Feed (c) The Royal Society of […]Alix Bastidas Ángel
- A ‘double locked’ ratiometric fluorescent probe for detection of cysteine in a viscous system and its application in cancer cells December 6, 2022Org. Biomol. Chem., 2022, Accepted ManuscriptDOI: 10.1039/D2OB01813F, PaperAjit Kumar Mahapatra, Sandip Kumar Samanta, Kalipada Maiti, Satyajit Halder, Uday Narayan Guria, Debasish Mandal, Kuladip JanaIntracellular viscosity is a physicochemical issue that regulates the consequences of several biological progressions. Cysteine (Cys) is an important signaling molecule that commands many cellular activities, such as antioxidant generation....The content of […]Ajit Kumar Mahapatra
- Visible-Light-Initiated External Photocatalyst-Free Synthesis of α,α-Difluoro-β-Ketoamides From 4-Aminocoumarins December 6, 2022Org. Biomol. Chem., 2022, Accepted ManuscriptDOI: 10.1039/D2OB01914K, PaperNingbo Li, Yuxin Wang, Shuo Gu, Chuqian Hu, Qian Yang, Zhaohui Jin, Wen-Tao Ouyang, jie qiao, Wei-Min HeA concise and efficient ring-opening difluorination strategy was developed for the synthesis of highly functionalized hydroxy-containing α,α-difluoro-β-ketoamides from the one-pot multicomponent reaction of 4-aminocoumarins, NFSI, and water in dimethyl carbonate...The content […]Ningbo Li
- Immobilization of a flavin molecule onto poly(methacrylic acid)s and its application in aerobic oxidation catalysis: effect of polymer stereoregularity December 5, 2022Org. Biomol. Chem., 2022, Accepted ManuscriptDOI: 10.1039/D2OB01834A, CommunicationYukihiro Arakawa, Yoshiko Sogabe, Keiji Minagawa, Miyuki Oshimura, Tomohiro Hirano, Koichi Ute, Yasushi ImadaThe isoalloxazine ring system, called flavin, was successfully immobilized on poly(methacrylic acid)s, PMAAs, with different tacticity via post-polymerization modification under suitable conditions. The resulting flavin-containing polymers showed catalytic activities for...The content of this RSS Feed […]Yukihiro Arakawa
- Deaminative defluoroalkylation of α‑trifluoromethylalkenes enabled by photoredox catalysis December 5, 2022Org. Biomol. Chem., 2022, Accepted ManuscriptDOI: 10.1039/D2OB02114E, CommunicationGuodong Zhang, Lei Wang, Liping Cui, Pan Gao, Feng ChenHerein, we disclose a new photoredox-catalyzed strategy to access gem-difluoroallylarenes from α-trifluoromethylalkenes with sterically hindered primary amines via C−N and C−F bond activation. This deaminative and defluorinative allylation is generally...The content of this RSS Feed (c) The Royal Society […]Guodong Zhang
- Synthesis of Quinoxaline Derivatives via Aromatic Nucleophilic Substitution of Hydrogen December 8, 2022
