RSC – Org. Biomol. Chem. latest articles- One-pot Synthesis of N-Sulfonylamidines from N-Acylsulfonamides Enabled by a Metal Triflate-Mediated Nonhydrolytic N-Deacylation† October 3, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB01296H, PaperJuan Tian, Mengyun Chen, Xinyi Wang, Xin Chen, Chengya Shao, Yiting Xiong, Yunfeng Liu, Dayong SangA triflate salt-catalyzed nonhydrolytic method for the deacylation of N-acylsulfonamides and subsequent one-pot condensation of the newly formed sulfonamides with N,N-dimethylformamide dimethyl acetal to provide N-sulfonylamidines is presented. A range...The content of this […]Juan Tian
- Highly selective recognition of fluoride using a trapezoidal cage October 3, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB01465K, CommunicationRuiye Wu, Caihong Mao, Feiying Ruan, Yan Cai, Xiaobo HuBy using a trapezoidal cage (1), highly selective recognition of F- (S>1000) was achieved in highly competitive environments composed of a large excess of various common anions. Through NMR, fluorescence,...The content of this RSS Feed (c) The Royal Society […]Ruiye Wu
- Palladium-catalyzed cross-coupling of arylcarboxylic acid 2-pyridyl esters with terminal alkynes October 3, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB01398K, PaperHang Yu, Jing-Jing Nie, Zhong-Xia WangIn the presence of Na2CO3 the combination of PdCl2(dppf), dppp and CuI catalyzes the decarbonylative coupling of arylcarboxylic acid 2-pyridyl esters with terminal alkynes to afford 1,2-disubstituted acetylenes. (Hetero)aryl, alkyl,...The content of this RSS Feed (c) The Royal Society of ChemistryHang Yu
- Synthesis and biological evaluation of lipid A derived from commensal Bacteroides October 3, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB01340A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Enrico C.J.M. Verpalen, Anna M. Ehlers, Aldo C.A. van Wingaarden, Arwin Brouwer, Geert-Jan BoonsThe inflammation-inducing properties of lipopolysaccharides (LPS) of gram-negative bacteria reside in its lipid A moiety. Bacillus fragilis, which is a […]Enrico C.J.M. Verpalen
- Visible-light-promoted C3-H alkoxycarbonylation of quinoxalin-2(1H)-ones or coumarins with alkyloxalyl chlorides October 2, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB01525H, CommunicationYanchun Lin, Xi Zhou, Yixuan Zheng, Bingran Chen, Yang Liu, Yi Zhang, Qiongjiao Yan, Wei Wang, Fener ChenHerein, we describe a green and efficient photoredox catalytic C3-H alkoxycarbonylation between quinoxalin-2(1H)-ones or coumarins and readily available alkyloxalyl chlorides under ambient conditions. A series of quinoxaline-3-carbonyl and coumarin-3-carbonyl compounds...The content […]Yanchun Lin
- Benzylamine promoted direct C–H arylation of arenes and heteroarenes via excitation with heat or light† October 2, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB01377H, PaperSouvik Chatterjee, Sabnam Azmi, Nilaj Bandopadhyay, Krishnendu Paramanik, Gayetri Sarkar, Bhaskar Biswas, Hari Sankar DasThe carbon-halogen bond cleavage in aryl halides by single electron transfer (SET) is the crucial step in radical-based cross-coupling reactions. Accomplishing such cleavage using an organic system without the assistance...The content of this RSS […]Souvik Chatterjee
- Synthesis of N-heterocyclic compounds using N,N-dimethylacetamides as an electrophilic carbon source October 2, 2024Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB01417K, PaperDayoung Chun, Seok Beom Lee, Simin Chun, Seung Hyun Choi, Junhwa Hong, Honghui Lee, Jinwoo Lee, Suckchang HongVarious N-heterocycles were successfully synthesized with nitrogen-containing nucleophiles and electrophilic carbon sources derived from N,N-dimethylacetamide (DMAc).To cite this article before page numbers are assigned, use the DOI form of citation above.The […]Dayoung Chun
- Synthesis of biaryl-based carbazoles via C-H functionalization and exploration of their anticancer activities October 2, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB01392A, PaperRamandeep Kaur, HARITHA DILIP, Sivapriya Kirubakaran, Srinivasarao Arulananda BabuThe synthesis of a library of new biaryl-based carbazoles via the bidentate directing group-assisted C-H functionalization and the preliminary screening of anticancer properties of biaryl-based carbazoles were reported. Different classes...The content of this RSS Feed (c) The Royal Society of […]Ramandeep Kaur
- Well-defined Cobalt(II) Catalyzed Synthesis of Perimidine Derivatives via Acceptorless Dehydrogenative Annulation October 2, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB01306A, CommunicationDebjyoti Pal, Rajashri Sarmah, Avijit Mondal, Itu Mallick, Dipankar SrimaniThe versatility of perimidine moiety offered a rich playground for researchers in field ranging from medical science to industrial chemistry. Herein, we described the first Co-catalyzed 2,3-Dihydro-1H-Perimidine synthesis via Acceptorless...The content of this RSS Feed (c) The Royal Society […]Debjyoti Pal
- Synthesis of N‑Heterocyclic amides from imidazoheterocycles through convergent paired electrolysis October 2, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB01115E, CommunicationElise Leclercq, Laura Chevet, Nicolas David, Muriel Durandetti, Laetitia Chausset BoissarieAn efficient ring opening of imidazoheterocycles induced by a direct C-H azidation resulting in an unusual formation of N‑Heterocyclic amides has been successfully developed through convergent paired electrolysis. A broad...The content of this RSS Feed (c) The Royal […]Elise Leclercq
- Redox Condensation of o-Halonitrobenzenes, Sulfur and Isothiocyanates: Access to 2-Aminobenzothiazoles October 1, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB01512F, CommunicationLe Anh Nguyen, Hung Dinh Mac, Pascal Retailleau, Thanh Binh NguyenElemental sulfur and isothiocyanates S8/RNCS couple was found to undergo redox condensation with o-halonitrobenzenes in the presence of N-methylpiperidine as a base in N-methylpyrrolidin-2-one to provide step- and redox- economical...The content of this RSS Feed (c) The Royal […]Le Anh Nguyen
- Synthesis of ω-functionalized ketones from strained cyclic alcohols by ring-opening and cross-recombination between alkyl and N-oxyl radicals October 1, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB01490A, PaperAlexander Budnikov, Igor Krylov, Mikhail I. Shevchenko, Lyubov' Sokova L. Sokova, Yan Liu, Bing Yu, Alexander Olegovich Terent'evRadical ring-opening oxyimidation of cyclobutanols and cyclopropanols with the formation of ω-functionalized ketones was discovered. The achieved oxidative C–O coupling proceeds via interception of a primary alkyl radical generated from...The content […]Alexander Budnikov
- L-Proline catalyzed multi-component synthesis of N-pyridyl-tetrahydroisoquinolines and their α-C(sp3)–H oxygenation October 1, 2024Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB01343C, PaperAditi Boruah, Mohit L. Deb, Ranjit Thakuria, Pranjal K. BaruahL-Proline catalysed synthesis of poly-substituted pyridines and further α-C(sp3)–H oxygenation of the tertiary amine moiety of the resultant pyridines are reported.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this […]Aditi Boruah
- Concise syntheses of (–)-quinocarcinol methyl ester and (–)-oxa-quinocarcinol methyl ester October 1, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB01363H, CommunicationZhongwen Wang, Tianhang Song, Yifan Wu, Jun RenA concise synthesis of (–)-quinocarcinol methyl ester was accomplished with an overall yield of 39% through a 9-step longest linear sequence (LLS). Our synthesis features a two-step ester reduction/reductive amination...The content of this RSS Feed (c) The Royal Society of ChemistryZhongwen Wang
- Anion Recognition Using meta-Substituted Ureidocalix[4]arene Receptors October 1, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB01441C, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Anastasia Surina, Jan Cejka, Karolina Salvadori, Pavel LhotakCalix[4]arenes bearing urea units in the meta position(s) of the upper rim of the macrocyclic skeleton were prepared by the reaction of the corresponding amines with […]Anastasia Surina
- Synthesis and Structural Confirmation of Selaginpulvilin X October 1, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB01529K, Communication Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Tereza Havlíková, Sundaravelu Nallappan, Ivana Cisarova, Lukas RycekWe report the first total synthesis of the natural product selaginpulvilin X, a selaginellaceae polyphenol class of compounds. Our synthetic strategy employs cross-coupling reactions and an […]Tereza Havlíková
- Straightforward Syntheses of Bottromycin Derivatives via Ugi-Reactions and Matteson Homologations October 1, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB01373E, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Etienne Bickel, Uli KazmaierNew bottromycin derivatives have been prepared using flexible Ugi and Matteson reactions. The Ugi reaction allows the fast and direct assembly of sterically hindered peptide fragments, while the Matteson homologation...The […]Etienne Bickel
- Copper(II) quinoxolinol imidazolium complexes in catalytic oxidation of benzylic and heterocyclic alcohols September 30, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB01081G, PaperXiaoyu Huo, Mariano Guagliardo, Anne E. V. GordenA novel copper(II) quinoxolinol complex has been prepared using a condensation reaction based on previous studies. The copper(II) quinoxolinol salen complex has been applied as catalyst using tert-butyl hydroperoxide (TBHP)...The content of this RSS Feed (c) The Royal Society of ChemistryXiaoyu Huo
- Thapsigargin: a promising natural product with diverse medicinal potential – a review of synthetic approaches and total syntheses September 30, 2024Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB01239A, Review ArticleAnisha Suresh, Dibyojeet Bagchi, Krishna P. KaliappanThapsigargin, a sesquiterpene lactone, has been known to the practitioners of traditional medicines as a cure for rheumatic pain and female infertility. This review discusses synthetic approaches and total syntheses of thapsigargin reported to date.To cite this article before page numbers […]Anisha Suresh
- Photocatalytic difunctionalization of arylalkenes with quinoxalinones and dialkyl dithiophosphoric acids September 30, 2024Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB01337A, CommunicationZhen WangThe photoredox eosin Y-catalyzed difunctionalization of alkenes with quinoxalinones and dialkyl dithiophosphoric acids was realized. This reaction exhibited excellent functional group compatibility.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of […]Zhen Wang
- One-pot Synthesis of N-Sulfonylamidines from N-Acylsulfonamides Enabled by a Metal Triflate-Mediated Nonhydrolytic N-Deacylation† October 3, 2024
