RSC – Org. Biomol. Chem. latest articles- Synthesis of the ABC Ring System of Kadlongilactones Tháng Một 31, 2023Org. Biomol. Chem., 2023, Accepted ManuscriptDOI: 10.1039/D2OB01701F, PaperLiang Li, Pengfei Li, Tianhao Li, Mingxiao Zhang, Wenjie Liu, Jing Li, Liang Wang, Yue ChenA racemic approach to the synthesis of ABC (7/7/5) ring system of Schisandra triterpenoid kadlongilactones is described. The synthesis features two key transformations: 1) conjugate addition followed by iodo-lactonization to...The content of this […]Liang Li
- Photoredox-catalyzed Trifluoromethylation of 2H-Indazoles Using TT-CF3+OTf− in Ionic Liquids Tháng Một 31, 2023Org. Biomol. Chem., 2023, Accepted ManuscriptDOI: 10.1039/D3OB00096F, PaperXin He, Zhicheng Chen, Xianghui Zhu, Hao Liu, Yanjie Chen, Zhizhong Sun, Wenyi ChuA protocol of metal and oxidant free photoredox-catalyzed trifluoromethylation of 2H-indazoles was developed by using Eosin Y as the photocatalyst and recoverable ionic liquids as the solvent. A series of...The content of this RSS Feed […]Xin He
- Synthesis, Kinetics and Cellular studies of new phenothiazine analogs as potent human-TLK inhibitors Tháng Một 31, 2023Org. Biomol. Chem., 2023, Accepted ManuscriptDOI: 10.1039/D2OB02191A, PaperSivapriya Kirubakaran, Delna johnson, Javeena Hussain, Siddhant Bhoir , Vaishali Chandrasekaran, Parul Sahrawat, Tanya Hans , Md Imtiaz Khalil, Arrigo De Benedetti, Vijay ThiruvenkatamThe alterations in the expression patterns of protein kinases often implicate human cancer initiation and progression. Human Tousled-like kinases (TLKs), both TLK1/1B and TLK2 are […]Sivapriya Kirubakaran
- Recent advances in the chemistry of aryltriazene Tháng Một 31, 2023Org. Biomol. Chem., 2023, Accepted ManuscriptDOI: 10.1039/D2OB02267B, Review ArticleTinglan Liu, Haipeng Wu, Qijing Zhang, Chengming WangTriazene is one of the most versatile building blocks in syntheiss. Generally, it is viewed as a safety equivalent of diazonium salt, thus immediately finds numerous applications in preparative chemistry...The content of this RSS Feed (c) The Royal Society of […]Tinglan Liu
- Azo-Tagged C4N4 Fluorophores: Unusual Overcrowded Structures and Their Applications to Fluorescent Imaging Tháng Một 30, 2023Org. Biomol. Chem., 2023, Accepted ManuscriptDOI: 10.1039/D3OB00049D, CommunicationKohei Miki, Naoki Takizawa, Ryosuke Tsutsumi, Wei Xu, Naoya KumagaiThe C4N4 fluorophore is an intense fluorescence emitter featuring a 2,5-diaminopyrimidine core comprising four carbon and four nitrogen atoms. A series of C4N4 derivatives was photochemically dimerized at the 5-amino...The content of this RSS Feed (c) The Royal Society […]Kohei Miki
- Synergistic or Antagonistic Antioxidant Combinations - A Case Study Exploring Flavonoid-Nitroxide Hybrids Tháng Một 28, 2023Org. Biomol. Chem., 2023, Accepted ManuscriptDOI: 10.1039/D2OB02101C, PaperAstrid Larin, Michael Pfrunder, Kathleen Mullen, Sandra Wiedbrauk, Nathan Boase, Kathryn Fairfull-SmithNeurodegenerative diseases impose a considerable medical and public health burden on populations throughout the world. Oxidative stress, an imbalance in prooxidant/antioxidant homeostasis that leads to the generation of reactive oxygen...The content of this RSS Feed (c) The […]Astrid Larin
- Synthesis of 2-(2-nitrophenyl)indoline-3-acetic acid derivatives via base-catalyzed cyclization of N-(2-nitrobenzyl)-2-aminocinnamic acid derivatives Tháng Một 27, 2023Org. Biomol. Chem., 2023, Advance ArticleDOI: 10.1039/D3OB00056G, CommunicationJu Hyeon Park, Jinjae Park, Cheol-Hong CheonThe first synthetic protocol for the synthesis of cis-2-(2-nitrophenyl)indoline-3-acetic acid derivatives was developed via base-catalyzed cyclization of N-(2-nitrobenzyl)-2-aminocinnamic acid derivatives.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The […]Ju Hyeon Park
- pseudo-Multicomponent 1,3-dipolar cycloaddition involving a metal-free generation of unactivated azomethine ylides Tháng Một 27, 2023Org. Biomol. Chem., 2023, Accepted ManuscriptDOI: 10.1039/D3OB00023K, PaperJosé Sansano, Asmaa Belabbes, Francisco Foubelo, Carmen Najera, Gracia Retamosa, Ana Sirvent, Miguel YusThe pseudo-multicomponent reaction between propargyl amine, an aldehyde and an electron-deficient alkene is described. The C-H activation takes place thermally and allows to obtain cicloadducts in very good yields and...The content of this RSS Feed […]José Sansano
- Furan-based inhibitors of pyruvate dehydrogenase: SAR study, biochemical evaluation and computational analysis Tháng Một 27, 2023Org. Biomol. Chem., 2023, Advance ArticleDOI: 10.1039/D2OB02272A, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Alex H. Y. Chan, Terence C. S. Ho, Daniel R. Parle, Finian J. LeeperMany neutral derivatives of the furan analogue of thiamine were tested to explore the SAR of the two thiamine pyrophosphate […]Alex H. Y. Chan
- Catalyst-Free Electrochemical Trifluoromethylation of Coumarins Using CF3SO2NHNHBoc as the CF3 Source Tháng Một 26, 2023Org. Biomol. Chem., 2023, Accepted ManuscriptDOI: 10.1039/D2OB01925F, CommunicationWenbo Chen, Nannan Cen, Han Wang, Yicheng Zhou, Ruoqu Gong, Dandan SuiAn efficient electrochemical trifluoromethylation of coumarins using CF3SO2NHNHBoc as the trifluoromethyl source was developed. Under catalyst-free and external oxidant-free electrolysis conditions, a range of 3-trifluoromethyl coumarins were obtained in moderate...The content of this RSS Feed (c) The […]Wenbo Chen
- Heart of gold: enabling ligands for oxidative addition of haloorganics in Au(I)/Au(III) catalysed redox-neutral cross-coupling reactions Tháng Một 26, 2023Org. Biomol. Chem., 2023, Accepted ManuscriptDOI: 10.1039/D3OB00002H, Review ArticleTerry McCallumThe field of Au-catalysis has been an area rich with new discoveries due to the unique properties of the lustrous element. In the past decade, developments in Au(I)/Au(III) cross-coupling methodology...The content of this RSS Feed (c) The Royal Society of ChemistryTerry McCallum
- A new reversible transformation of oxindolylidene derivatives of imidazothiazolotriazine into 3-[(imidazotriazin-3-yl)thio]-2-oxoquinoline-4-carboxylates Tháng Một 26, 2023Org. Biomol. Chem., 2023, Accepted ManuscriptDOI: 10.1039/D2OB02242G, PaperAlexei N. Izmest'ev, Angelina N. Kravchenko, Galina A. GazievaA simple method for the synthesis of water soluble potassium 3-[(imidazotriazin-3-yl)thio]-2-oxoquinoline-4-carboxylates was developed based on a new reversible transformation of oxindolylidene derivatives of imidazothiazolotriazine upon treatment with potassium hydroxide. The...The content of this RSS Feed (c) The Royal Society of […]Alexei N. Izmest'ev
- Visible Light-Induced Ternary Electron Donor-Acceptor Complex Enabled Synthesis of 2-(2-Hydrazinyl) thiazole Derivatives and The Assessment of Their Antioxidant and Antidiabetic Therapeutic Potential Tháng Một 26, 2023Org. Biomol. Chem., 2023, Accepted ManuscriptDOI: 10.1039/D2OB02308C, PaperMd. Firoj Hossain, Sovan Dey, Arindam Das, Ram Naresh Yadav, Palash Jyoti Boruah, Prerana Bakli, Tania Baishya, Koushik Sarkar, Anup Barman, Ranabir Sahu, Biplab Maji, Amit Kumar PaulA mild and eco-friendly visible-light-induced synthesis of 2-(2-Hydrazinyl) thiazole from readily accessible thiosemicarbazide, carbonyl, and phenacyl bromide in the absence of […]Md. Firoj Hossain
- Generating water/MeOH-soluble and luminescent polymers by grafting 2,6-bis(1,2,3-triazol-4-yl)pyridine (btp) ligands onto a poly(ethylene-alt-maleic anhydride) polymer and cross-linking with terbium(III) Tháng Một 25, 2023Org. Biomol. Chem., 2023, Advance ArticleDOI: 10.1039/D2OB02259A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Isabel N. Hegarty, Adam F. Henwood, Samuel J. Bradberry, Thorfinnur GunnlaugssonThe synthesis of two new green emitting polymers, made by reacting the btp ligand 1 with the commercially available P(E-alt-MA) polymer and cross-linking […]Isabel N. Hegarty
- Total Synthesis of (–)-Domoic Acid, A Potent Ionotropic Glutamate Receptor Agonist and the Key Compound in Oceanic Harmful Algal Blooms Tháng Một 25, 2023Org. Biomol. Chem., 2023, Accepted ManuscriptDOI: 10.1039/D2OB02325C, CommunicationShigeru Nishizawa, Hitoshi Ouchi, Hiroto Suzuki, Takuma Ohnishi, Shingo Sasaki, Yu Oyagi, Masaki Kanakogi, Yoshitaka Matsumura, Shunsuke Nakagawa, Tomohiro Asakawa, Masahiro Egi, Makoto Inai, Fumihiko Yoshimura, Ryo TAKITA, Toshiyuki KanThe stereo-controlled total synthesis of (–)-domoic acid is described. The critical construction of C1’-C2’ Z-configuration was accomplished by taking […]Shigeru Nishizawa
- Recent progress in the oxidative bromination of arenes and heteroarenes Tháng Một 25, 2023Org. Biomol. Chem., 2023, Advance ArticleDOI: 10.1039/D3OB00019B, Review ArticleDa-Bo Jiang, Fei-Yue Wu, Hai-Lei CuiThis review summarizes recent developments in the field of oxidative preparation of bromoarenes and bromoheteroarenes covering from 2012 to 2022.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The […]Da-Bo Jiang
- NHC-catalyzed [3 + 3] cycloaddition of α-bromoenals with nitroketene aminals or nitroketene N,S-acetals: synthesis of nitro-containing dihydropyridin-2-ones Tháng Một 25, 2023Org. Biomol. Chem., 2023, Advance ArticleDOI: 10.1039/D2OB02334B, CommunicationYarui Li, Xiaoxia Huang, Shiyong Peng, Jian Wang, Ming LangAn efficient N-heterocyclic carbene (NHC)-catalyzed [3 + 3] cycloaddition of α-bromoenals with β-nitro enamines has been developed.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The […]Yarui Li
- Visible/solar-light-driven thiyl-radical-triggered synthesis of multi-substituted pyridines Tháng Một 24, 2023Org. Biomol. Chem., 2023, Advance ArticleDOI: 10.1039/D3OB00009E, PaperAshish Kumar Sahoo, Amitava Rakshit, Avishek Pan, Hirendra Nath Dhara, Bhisma K. PatelA light-mediated synthesis of thio-functionalized pyridines has been achieved using γ-ketodinitriles and thiophenols under green LED irradiation or direct sunlight.To cite this article before page numbers are assigned, use the DOI form of citation above.The content […]Ashish Kumar Sahoo
- Metal-free direct C-6–H alkylation of purines and purine nucleosides enabled by oxidative homolysis of 4-alkyl-1,4-dihydropyridines at room temperature Tháng Một 24, 2023Org. Biomol. Chem., 2023, Advance ArticleDOI: 10.1039/D2OB02070J, PaperQingsong Jiang, Xiguang Liu, Weili Wang, Yiwen Chen, Mingwu YuThe highly C6-regioselective alkylation of purines and purine nucleosides via oxidative homolysis of 4-alkyl-1,4-dihydropyridines at room temperature without metal catalysts and additional acids is reported for the first time.To cite this article before page numbers are assigned, use the […]Qingsong Jiang
- Asp-containing actinomycin and tetracyclic chromophoric analogues from the Streptomyces sp. strain S22 Tháng Một 24, 2023Org. Biomol. Chem., 2023, Advance ArticleDOI: 10.1039/D2OB02247H, PaperWanzhu Zhao, Guangfei Wang, Lin Guo, Jingmin Wang, Congcong Jing, Ben Liu, Feng Zhao, Shumin Zhang, Zeping XieFirst Asp-containing actinomycin and two unusual tetracyclic chromophoric analogues with potent cytotoxic and antibacterial activities from marine-derived Streptomyces sp. strain S22.To cite this article before page numbers are assigned, use the DOI form […]Wanzhu Zhao
- Synthesis of the ABC Ring System of Kadlongilactones Tháng Một 31, 2023
