RSC – Org. Biomol. Chem. latest articles- Measuring Local pH at Interfaces from Molecular Tumbling: A Concept for Designing EPR-active pH-sensitive Labels and Probes Tháng Tư 17, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00167B, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Maxim Voinov, Nicholas Nunn, Roshan Rana, Atli Davidsson, Alex Smirnov, Tatyana SmirnovaMolecular probes and indicators are broadly employed for pH measurements in bulk media and at interfaces. The underlying physical principle of pH […]Maxim Voinov
- Base- and Sulfur- Promoted Oxidative Lactonization of Chalcone-Acetate Michael Adducts: Access to Pyran-2-ones Tháng Tư 17, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00479E, CommunicationCao Nguyen Nguyen, Duc Toan Nguyen, Ha An Tran, Hung Dinh Mac, Thi Thu Tram Nguyen, Pascal Retailleau, Thanh Binh NguyenA cost-effective, practical, straightforward and scalable synthesis of α-pyrones via base- and sulfur-promoted annulation of phenylacetates and chalcones. Generated in situ from the starting components by using dbu […]Cao Nguyen Nguyen
- Revisiting Biginelli-like Reactions: Solvent Effects, Mechanisms, Biological Applications and Correction of Several Literature Reports Tháng Tư 17, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00272E, PaperBrenno A. D. Neto, Pedro Beck, Arthur Leitão, Yasmin Santana, Jose R. Correa, Carime Vitória da Silva Rodrigues, Daniel Machado, Guilherme Matos, Luciana Machado Ramos, Claudia Cristina Gatto, Carlos Kleber Z. Andrade, Sarah CaldasThis study critically reevaluates reported Biginelli-like reactions using a Kamlet-Abboud-Taft-based solvent effect model. Surprisingly, structural […]Brenno A. D. Neto
- Electro-oxidative three-component cascade coupling of isocyanides with elemental sulfur and amines for the synthesis of 2-aminobenzothiazoles Tháng Tư 17, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00432A, PaperPeng-Fei Huang, Jia-Le Fu, Ying Peng, Jian-Hong Fan, Long-Jin Zhong, Kewen Tang, Yu Liu2-Aminobenzothiazoles are commonly encountered in various functional compounds. Herein, we disclose an electro-oxidative three-component reaction for the effective synthesis of 2-aminobenzothiazoles under mild conditions, utilizing non-toxic and abundant elemental sulfur...The content of this RSS Feed […]Peng-Fei Huang
- Photoproperties of Favipiravir and their 6-Substituted Analogues: Fluorescence Controlled through Halogen Substitution and Tautomerism Tháng Tư 17, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00397G, PaperAngel H Romero, Marcos Couto, Ivan E Romero, German Fuentes, Matías N. MöllerHerein, we showed the photophysical properties of the favipiravir and their 6-substituted analogues. Also, we interpreted the origin of the fluorescence of the favipiravir and their 6-substituted analogues as function...The content of this RSS Feed (c) […]Angel H Romero
- Efficient Synthesis of SCF3-Containing 3-Alkenylquinoxalinones via Three-Component Radical Cascade Reaction Tháng Tư 16, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00363B, PaperSi-Yu Wang, Chu Liu, Wei Yang, Zhong-Ying Tian, Lin Yuan, Long-Yong XieAn efficient and practical method for the synthesis of 3-alkenylquinoxalinones containing SCF3 group has been readily developed through a three-component radical cascade reaction involving quinoxalinones, alkynes and AgSCF3. The reaction...The content of this RSS Feed (c) The […]Si-Yu Wang
- Exploring the mechanism of the reductive amination of acetophenones via Borch approach: the role of the acid catalyst Tháng Tư 16, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00160E, PaperJoão Pedro Albuquerque Souza, Amanda Krauskopf Jacobs, Leandro Piovan, Renan Borsoi CamposThe energetic viability of several mechanistic variations of the reductive amination of acetophenones via the Borch approach was reexamined through density functional theory calculations. The crucial involvement of the acid...The content of this RSS Feed (c) The […]João Pedro Albuquerque Souza
- Tetrabutylammonium decatungstate (TBADT), a compelling and trailblazing catalyst for visible-light-induced organic photocatalysis. Tháng Tư 15, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00171K, Review ArticleBor-Cherng Hong, Ranadheer Reddy IndurmuddamTetrabutylammonium decatungstate (TBADT) has recently emerged as an intriguing photocatalyst under visible-light or near-visible-light irradiation in a wide range of organic reactions that were previously not conceivable. Given its ability...The content of this RSS Feed (c) The Royal Society of ChemistryBor-Cherng Hong
- Design, Synthesis, and Biological Application of A-D-A Type Boranil Fluorescent Dyes Tháng Tư 15, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00297K, PaperWei Luo, Yiling Li, Liang Wang, Yanhua Qin, Qiao Cheng, Guochang Hu, Chaoyi Yao, Xiangzhi SongFor the first time, three acceptor-donor-acceptor (A-D-A) type Boranil fluorescent dyes, CSU-BF-R (R = H, CH3, OCH3), featuring phenothiazine as the donor, were designed and synthesized. CSU-BF-R exhibited remarkable photophysical...The content of this […]Wei Luo
- Recent developments in the enzymatic modifications of steroid scaffolds Tháng Tư 15, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00327F, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Huibin Wang, Ikuro AbeSteroids are an important family of bioactive compounds. Steroid drugs are renowned for their multifaceted pharmacological activities and are the second-largest category in the global pharmaceutical market. Recent developments […]Huibin Wang
- Stereoselective Synthesis of gem-Dihalopiperidines via Halo-Aza-Prins Cyclization Reaction: Access to Piperidin-4-ones and Pyridines Tháng Tư 15, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00338A, PaperAnil Kumar Saikia, Surjya Kumar Bora, Subhamoy Biswas, Bipin Kumar BeheraAn efficient methodology for the synthesis of 4,4-dihalopiperidine derivatives has been developed from N-(3-halobut-3-en-1-yl)-4-methylbenzenesulfonamide and aldehyde catalyzed by In(OTf)3 in excellent yields. The reaction involves an initial formation of six...The content of this RSS Feed (c) The Royal […]Anil Kumar Saikia
- Total synthesis of diplofuranone A and diapolic acid A Tháng Tư 15, 2024Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00433G, CommunicationDattatraya H. Dethe, Vimlesh Kumar, Nagabhushana C. BeeralingappaThe first and concise syntheses of the anticancer agent diplofuranone A and the fatty acid-derived metabolite diapolic acid A have been demonstrated using easily accessible and commercially available starting materials.To cite this article before page numbers are assigned, use the DOI […]Dattatraya H. Dethe
- Catalyst- and base-free visible light-enabled radical relay trihalomethylation/functional group-migration/carbonylation with CX3SO2Cl Tháng Tư 15, 2024Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00292J, PaperJinkai Hu, Chenglei Yang, Xiaotao Qin, Hui Liu, Tongtong Ma, Ao-tong Shi, Qing-Long Lv, Xingman Liu, Jinhui Yang, Dianjun LiA visible light-enabled photocatalyst-free radical trihalomethylation/cyano (or benzo[d]thiazol-2-yl) 1,4-migration/carbonylation reaction of 2-hydroxy-2-hex-5-enenitrile (or (benzo[d]thiazol-2-yl)-pent-4-enol) with CX3SO2Cl (X = F, Cl) is reported.To cite this article before page numbers are […]Jinkai Hu
- BBr3-mediated dearomative spirocyclization of biaryl ynones: facile access to spiro[5.5]dienones Tháng Tư 15, 2024Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00274A, CommunicationGaurav Jaiswal, Subhas Chandra PanBBr3 mediated dearomative spirocyclization of biaryl ynones has been reported for the direct synthesis of spiro[5.5]dienones with a tri-substituted double bond.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal […]Gaurav Jaiswal
- Nickel-catalysed regio- and stereoselective hydrocyanation of alkynoates and its mechanistic insights proposed by DFT calculations Tháng Tư 15, 2024Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00380B, CommunicationShigeru Arai, Koichi Nakazawa, Xiao-Fei Yang, Masaya Nakajima, Shinji Harada, Atsushi NishidaThis work discloses the origin of regio- and stereoselectivity of hydrocyanation of alkynoates.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society […]Shigeru Arai
- Reduction of sulfoxides catalyzed by the commercially available manganese complex MnBr(CO)5 Tháng Tư 15, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00204K, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Daniel Leal Lourenço, Ana Cristina FernandesA new methodology for the reduction of a wide variety of aliphatic and aromatic sulfoxides catalyzed by the air-stable, cheap and commercially available manganese catalyst MnBr(CO)5 with excellent […]Daniel Leal Lourenço
- Dess–Martin periodinane-mediated oxidation of the primary alcohol of cytidine into a carboxylic acid Tháng Tư 15, 2024Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00240G, Communication Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Alexandra R. E. Serre, Vibhu Jha, Adèle Rivault, Leif A. Eriksson, Goreti Ribeiro Morais, Robert A. FalconerHerein we describe the first example of the conversion of the primary alcohol of cytidine into a […]Alexandra R. E. Serre
- Cu(OTf)2/HFIP catalyzed regioselective cycloisomerization of indole-C3-functionalized alkynols to carbazoles Tháng Tư 14, 2024Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00421C, CommunicationSrinivasarao Yaragorla, Tabassum Khan, Sayonika ChakrobortyWe report here a simple and atom economic cycloisomerization reaction of indole-tethered alkynols for constructing diverse carbazoles via 1,2-alkly migration using Cu(OTf)2/HFIP as the excellent promoter system.To cite this article before page numbers are assigned, use the DOI form of citation above.The content […]Srinivasarao Yaragorla
- FeCl3-Catalyzed Three-Component Reaction for the Synthesis β-(1,2,3-Triazolyl)-Ketones by Using DMF as One Carbon Source Tháng Tư 14, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00207E, CommunicationRuilin Fang, Lei Zheng, Xuyang Chen, Can Wang, Yunfeng ChenAn FeCl3-catalyzed oxidative condensation of NH-1,2,3-triazoles and aryl methyl ketones (or acetophenones) and DMF (N,N-dimethylformamide) for the synthesis of β-(1,2,3-triazolyl)-ketones was developed. DMF serves as one carbon source, and the...The content of this RSS Feed (c) The Royal Society […]Ruilin Fang
- Chemoenzymatic total synthesis of rotigotine via IRED-catalyzed reductive amination Tháng Tư 14, 2024Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00072B, CommunicationDongyu Tang, Yaqing Ma, Jinping Bao, Shushan Gao, Shuli Man, Chengsen CuiAn engineered imine reductase (IRED) was developed specifically for 2-tetralone substrate, and utilized in the total synthesis of rotigotine.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this […]Dongyu Tang
- Measuring Local pH at Interfaces from Molecular Tumbling: A Concept for Designing EPR-active pH-sensitive Labels and Probes Tháng Tư 17, 2024
