RSC – Org. Chem. Front. latest articles
- DBU-Catalyzed Substitution-Controlled Synthesis of Oxa[3.3.1] Bridged Ring and Naphthylamine Derivatives March 26, 2024Org. Chem. Front., 2024, Accepted ManuscriptDOI: 10.1039/D4QO00012A, Research ArticleShiyu Xu, Zhihui Sun, Pengyutian Liu, Yuanlin Wei, Fan Sun, Man Zhao, Ying Wang, Ming Zhang, Guofeng Li, Hong LiangA switchable cascade cyclization reaction of ortho-alkynyl arylketones with amines has been developed. The different reaction pathways are controlled by the substituent of the α-carbon of in-situ generated […]Shiyu Xu
- Synthesis of 10B-enriched 2,1-Borazaronaphthalenes from o-Aminostyrenes and 10BF3 March 26, 2024Org. Chem. Front., 2024, Accepted ManuscriptDOI: 10.1039/D4QO00176A, Research ArticleWeihua Qiu, Jide Zhu, Rencai Tao, Kai Yang, Qiuling SongHerein we present a practical approach for preparing 10B-enriched 2,1-borazaronaphthalenes from o-aminostyrenes and 10BF3 (primary source of boron-10) in the presence of chlorosilane. The synthetic potential of this transformation is...The content of this RSS Feed (c) The Royal […]Weihua Qiu
- Photoredox Catalyzed Hydroazolylation of Alkenes via Phosphoranyl Radicals March 26, 2024Org. Chem. Front., 2024, Accepted ManuscriptDOI: 10.1039/D4QO00233D, Research ArticleFan Zhu, Zhi Qiao, Na He, Chunxiao Nong, Qiping He, Meilan Xi, Xizhong Song, Jun Lin, Jingbo Chen, Yi JinHerein, a general protocol for the hydroazolylation of alkenes with N-hydroxyl azoles is reported. These reactions proceed via a phosphoranyl radical that is accessed by photoredox catalysis, followed […]Fan Zhu
- The synthesis of isoxazolines and dihydrooxazines by Pd-catalyzed oxyalkynylation alkenyl oximes with alkynyl bromides March 25, 2024Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00263F, Research ArticleCangzhu Hu, Shiji Xu, Qiang Wang, Jing Sun, Ying Han, Chao-Guo Yan, Lei WangSynthesis of isoxazolines and dihydrooxazines bearing an alkyne group by Pd-catalyzed oxyalkynylation of alkenyl oximes with alkynyl bromides. This new approach has a broad substrate scope and good functional tolerance.To cite this article before […]Cangzhu Hu
- Platform for 3-fluoro-3-hydroxyoxindoles: photocatalytic C–N cross-coupling and deaminative oxidation–fluorohydroxylation March 25, 2024Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00285G, Research ArticleLetian Zhang, Yibin Wang, Jiabin Shen, Hao Xu, Chao ShenA photocatalytic C–N cross-coupling and deaminative fluorinating strategy has been developed to afford 3-fluoro-3-hydroxyoxindoles with wide functionality tolerance and good yields.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of […]Letian Zhang
- Diazenylation of active methyne compounds via arylazo sulfones March 23, 2024Org. Chem. Front., 2024, Accepted ManuscriptDOI: 10.1039/D4QO00343H, Research ArticleRuiqing Wang, Lingkai Kong, Xinyu Zong, Minghui Zhang, Wenyi Chen, Yaxin Liu, Lingjuan Ma, Yulei ZhaoA diazenylation reaction between active methyne compounds and arylazo sulfones is reported. The mild reaction involves an initial azotization, followed by a nucleophilic addition-elimination. The acyl group plays a dual...The content of […]Ruiqing Wang
- Organocatalyzed double dearomatization reaction of non-functionalized phenols and propargylic alcohols: the important regulating effect of steric hindrance March 23, 2024Org. Chem. Front., 2024, Accepted ManuscriptDOI: 10.1039/D4QO00103F, Research ArticleXihong Liu, Boyan Zhu, Panpan Zhou, Jingying Zhang, Anqi Chu, Rui WangWhile Friedel-Crafts (F-C) reaction was widely used for the preparation of functionalized benzylic compounds, the interrupted F-C reaction that allows for the synthesis of stable dearomatized cyclic systems has rarely...The content of this RSS Feed (c) […]Xihong Liu
- Practical photocatalytic hydroalkylation of alkenes with chloroacetates mediated by formate ion March 22, 2024Org. Chem. Front., 2024, Accepted ManuscriptDOI: 10.1039/D4QO00228H, Research ArticleEkaterina V. Malakhova, Vladislav S. Kostromitin, Vitalij V. Levin, Alexander DilmanProcesses that use commodity chemicals as substrates and reagents and that result in the formation of C,C bond are highly desirable. Herein, a method for the radical alkylation of simple...The content of this RSS Feed (c) The […]Ekaterina V. Malakhova
- Contributors to the Organic Chemistry Frontiers Emerging Investigator Series 2022–2023 March 22, 2024Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO90025A, ProfileThis profile article showcases researchers who have contributed an article to the Organic Chemistry Frontiers Emerging Investigator Series.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry
- Modular Synthesis of C2-Symmetric Nitrogen-Containing Polyaromatics via Visible Light-enabled Tandem Reductive Aza-6π Electrocyclization March 22, 2024Org. Chem. Front., 2024, Accepted ManuscriptDOI: 10.1039/D4QO00140K, Research ArticleQun-Liang Zhang, Qing-Tian Fan, yirong zhou, Jingli Zhang, Fanglin ZhangNitrogen-containing polyaromatic compounds (N-PACs) show wide applications in synthetic chemistry and materials science, however their highly efficient preparation with structurally precise control remained a big challenge. Herein, we report an...The content of this RSS Feed (c) The Royal […]Qun-Liang Zhang
- Mn(III)-catalyzed arylboronic acids-based cascade reaction via nonclassical organometallic-radical mechanism March 22, 2024Org. Chem. Front., 2024, Accepted ManuscriptDOI: 10.1039/D4QO00244J, Research ArticleHuimin Qian, Jiangdong Zhang, Shun-Jun Ji, Xiao-Ping XuAn efficient cascade reaction of arylboronic acids, o-cyanoaryl isocyanides, and indoles catalyzed by manganese(III) acetylacetonate which enables the construction of a series of 2-(1H-indol-3-yl)-2-phenylindolin-3-imines was developed. The transformation features high...The content of this RSS Feed (c) The Royal Society of […]Huimin Qian
- Tetra-azobenzene extended calix[4]pyrroles: influence of photo-isomerization on chloride binding and its transport through liposomal membranes March 22, 2024Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00399C, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Pedro Ferreira, Gemma Aragay, Pablo BallesterPhoto-modulation in chloride binding affinity and transmembrane transport with tetra-azobenzene extended calix[4]pyrroles.To cite this article before page numbers are assigned, use the DOI form of citation above.The […]Pedro Ferreira
- Pd(II)-Catalyzed Denitrative Alkyne Annulation Reaction for the Synthesis of Cyclopenta[b]chromanes March 22, 2024Org. Chem. Front., 2024, Accepted ManuscriptDOI: 10.1039/D4QO00344F, Research ArticlePratiksha Bhorali, Deep J Kalita, Babulal Das, Sanjib GogoiAn unprecedented Pd(II)-catalyzed annulation reaction is developed for the synthesis of cyclopenta[b]chromane derivatives bearing tertiary hydroxyl group. In this reaction, readily available 2-(2-nitrovinyl)phenols are annulated with two molecules of disubstituted...The content of this RSS Feed (c) The Royal Society […]Pratiksha Bhorali
- Synthesis of multisubstituted carbazol-4-amines from tetra-hydrocarbazol-4-one oximes March 22, 2024Org. Chem. Front., 2024, Accepted ManuscriptDOI: 10.1039/D4QO00386A, Research ArticleJiahua Wang, Dandan Gao, Aanuoluwapo O. Oyejobi, Na Ji, Xiang-Ying Tang, Long WangDescribed herein is a sequential thiolation reaction between tetrahydrocarbazol-4-one oximes and aryl thiols, affording a wide range of 1,3-dithiolated carbazol-4-amines, which are hardly accessible by other traditional methods. The reaction...The content of this RSS Feed […]Jiahua Wang
- C–H Activation-Enabled Synthesis of A Piperazine-Embedded Azadibenzo[a,g]corannulene Analogue March 21, 2024Org. Chem. Front., 2024, Accepted ManuscriptDOI: 10.1039/D4QO00415A, Research ArticleLin Huang, Mengyu Qiu, Zhihao Chang, Duncan L. Browne, Jianhui HuangA novel piperazine-embedded azadibenzo[a,g]corannulene analogue was synthesized by a four-step bottom-up synthesis, including a nucleophilic aromatic substitution (SNAr) and a palladium-catalyzed intramolecular C–H activation arylation as key steps. This intriguing...The content of this RSS Feed (c) The […]Lin Huang
- An eight-membered ring formed by the Scholl reaction of o-quateraryls March 19, 2024Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00029C, Research ArticleXinhe Yang, Man Gao, Han Chen, Qi Gong, Qian MiaoThe Scholl reaction of o-quateraryls demonstrates regioselectivity, forming an eight-membered ring when the terminal aryl groups are significantly more electron-rich than the internal arylene groups, yielding tetraphenylene derivatives.To cite this article before page numbers are assigned, use the […]Xinhe Yang
- Photoinduced cobalt catalyzed site selective alkylation of 2-pyridones March 19, 2024Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D3QO02133E, Research ArticleChenyue Li, Jing Li, Zibin Jiang, Yiwei Xu, Hujie Xiong, Fei-Long Liu, Tingting Liu, Fei Ye, Chenggui WuA selective C3- and C6-alkylation reaction of 2-pyridone by a direct C–H functionalization approach was used to access 2-pyridone derivatives, utilizing a photo-induced cobalt-catalyzed alkyl radical selective addition process.To cite […]Chenyue Li
- H2O/D2O as the only H/D source for photocatalytic phosphine-mediated radical transfer hydrogenation/deuteration of α-aryl imino esters March 19, 2024Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00446A, Research ArticleYao Zhong, Xinhan Li, Xiaohan Zhao, Ruifeng Fan, Jianbin Xu, Baomin FanA method for the transfer hydrogenation of α-aryl imino esters using photocatalytic water as the sole hydrogen source has been developed. The substrate is wildely applicable and the yield is up to 99%.To cite this article […]Yao Zhong
- Concise synthesis of pyrrolo[3,4-c]quinolines via a P(NMe2)3-catalyzed [4 + 2] annulation followed by a Zn/AcOH-mediated reduction–hydroamination–isomerization March 18, 2024Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00169A, Research ArticleZhengyang Chen, Dan Xiong, Nengzhong Wang, Yufei Zhang, Hui Yao, Jinkun Zhang, Nianyu Huang, Kun ZouA P(NMe2)3-catalyzed [4 + 2] annulation of 2-amino-β-nitrostyrenes and β′-acetoxy allenoates followed by a Zn/AcOH-mediated reduction–hydroamination–isomerization has been developed.To cite this article before page numbers are assigned, use the DOI form of […]Zhengyang Chen
- Oxidative cyclization and enzyme-free deiodination of thyroid hormones March 18, 2024Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00220B, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Julian Spils, Lucien D. Caspers, Pim Puylaert, Boris J. NachtsheimThis study, unveils a novel pathway for thyroid hormone interconversion, synthesizing an iodonium T4 species, followed by selective deiodination to an oxidized T3. […]Julian Spils
- DBU-Catalyzed Substitution-Controlled Synthesis of Oxa[3.3.1] Bridged Ring and Naphthylamine Derivatives March 26, 2024