RSC – RSC Chem. Biol. latest articles- Halogenation of nucleic acid structures: From chemical biology to supramolecular chemistry May 21, 2025RSC Chem. Biol., 2025, Accepted ManuscriptDOI: 10.1039/D5CB00077G, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Catalina Nicolau, Julia M. Requena-Ramírez, Jorge Gonzalez, Antonio BauzaHalogenation of organic molecules is a widespread resource used in the fields of chemical biology and rational drug design to improve the binding affinity […]Catalina Nicolau
- RaPID discovery of cell-permeable helical peptide inhibitors con-taining cyclic β-amino acids against SARS-CoV-2 main protease May 20, 2025RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D5CB00021A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Marina Kawai, Tika R. Malla, H. T. Henry Chan, Anthony Tumber, Lennart Brewitz, Eidarus Salah, Naohiro Terasaka, Takayuki Katoh, Akane Kawamura, Christopher J. Schofield, Fernanda Duarte, Hiroaki SugaThe ribosomal synthesis of a helical […]Marina Kawai
- Unravelling the role of key amino acid residues of the parainfluenza fusion peptide in membrane fusion May 20, 2025RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D5CB00058K, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Mariana Valério, Carolina C. Buga, Diogo A. Mendonça, Miguel A. R. B. Castanho, Manuel N. Melo, Cláudio M. Soares, Diana Lousa, Ana Salomé VeigaParainfluenza viruses entry relies on membrane fusion promoted by the […]Mariana Valério
- Dehydroglutathione, a glutathione derivative to introduce non-reversible glutathionylation May 20, 2025RSC Chem. Biol., 2025, Accepted ManuscriptDOI: 10.1039/D5CB00052A, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Daniel Oppong, Rayavarapu Padmavathi, Dhanushika S. K. Kukulage, Madhu Chakkere Shivamadhu, Elizabeth Aline Newberry, Anneliese M. Faustino, Hsin-Yao Tang, Young-Hoon AhnProtein cysteine is susceptible to diverse oxidations, including disulfide, S-sulfenylation, S-nitrosylation, and S-glutathionylation, […]Daniel Oppong
- A general and accessible approach to enrichment and characterisation of natural anti-Neu5Gc antibodies from human samples May 14, 2025RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D5CB00073D, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Esme Hutton, Yumiko Uno, Emma Scott, Craig Robson, Martin A. Fascione, Nathalie SignoretA workflow to enrich and detect anti-Neu5Gc antibodies from individual plasma specimens, using CMAH-transfected human cells as a source of Neu5Gc-containing […]Esme Hutton
- Turn-on fluorescent glucose transport bioprobe enables wash-free real-time monitoring of glucose uptake activity in live cells and small organisms May 11, 2025RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D4CB00239C, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Monica S. Hensley, David Hutchings, Aldelrahman Ismail, Marina TanasovaThe “turn-on” glucose transport-targeting molecular probe provides an effective tool for detection and evaluation of alterations in glucose uptake efficiency in cells and small organisms.To […]Monica S. Hensley
- Cysteine sulfinic acid and sulfinylated peptides May 8, 2025RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D5CB00040H, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Laura Hayward, Matthias G. J. BaudCysteine sulfinic acid (CSA) is a stable post translational modification in nature.To cite this article before page numbers are assigned, use the DOI form of citation above.The […]Laura Hayward
- Mechanistic insights into the ATP-mediated and species-dependent inhibition of TrpRS by chuangxinmycin May 8, 2025RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D5CB00060B, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Yichen Ren, Sili Wang, Wen Liu, Jing Wang, Pengfei FangMultidimensional structural and mechanistic analyses elucidate the molecular basis of chuangxinmycin's species-selective inhibition of bacterial tryptophanyl-tRNA synthetases.To cite this article before page numbers are […]Yichen Ren
- Engineering regiospecific methylation of the pladienolides May 7, 2025RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D5CB00068H, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Emily R. Smith, Dua H. Al-Smadi, Yitao Dai, Manead Khin, Joanna E. Burdette, Brendan M. Duggan, James J. La Clair, Alessandra S. Eustáquio, Michael D. BurkartMethods were developed to regioselectively methylate pladienolide B […]Emily R. Smith
- An iridium(III) monosulfur-substituted chlorotetrazine complex for cysteine conjugation, bioimaging and photoactivatable therapy May 6, 2025RSC Chem. Biol., 2025, Accepted ManuscriptDOI: 10.1039/D4CB00316K, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Lili Huang, Justin Shum, Lawrence Cho-Cheung Lee, Guang-Xi Xu, Peter Kam-Keung Leung, Kenneth Kam-Wing LoPhotoactivatable systems have received considerable attention in the development of diagnostics and therapeutics due to their noninvasive nature and […]Lili Huang
- Halogenation of nucleic acid structures: From chemical biology to supramolecular chemistry May 21, 2025
