RSC Chemical Biology

RSC – RSC Chem. Biol. latest articles

• Characterization of the Baeyer–Villiger monooxygenase in the pathway of the bacterial pyrrolizidine alkaloids, legonmycins September 29, 2024
  RSC Chem. Biol., 2024, Advance ArticleDOI: 10.1039/D4CB00186A, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Shan Wang, Fleurdeliz Maglangit, Qing Fang, Kwaku Kyeremeh, Hai DengThe Baeyer–Villiger monooxygenase (BVMO), LgnC, plays a crucial role in the biosynthesis of bacterial pyrrolizidine alkaloids, legonmycins.To cite this article before page numbers are […]
  Shan Wang
• Bispecific FpFs: a versatile tool for preclinical antibody development September 26, 2024
  RSC Chem. Biol., 2024, Advance ArticleDOI: 10.1039/D4CB00130C, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Matthew Collins, Nkiru Ibeanu, Wiktoria Roksana Grabowska, Sahar Awwad, Peng T. Khaw, Steve Brocchini, Hanieh KhaliliWe previously described FpFs ̲ (Fab–PEG–Fab) as binding mimetics of IgGs.To cite this article before page numbers are […]
  Matthew Collins
• CyaY and TusA regulate ISC- and SUF-mediated L-cysteine desulfurase activity September 26, 2024
  RSC Chem. Biol., 2024, Advance ArticleDOI: 10.1039/D4CB00225C, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Paolo Olivieri, Jason C. Crack, Angelika Lehmann, Nick E. Le Brun, Silke LeimkühlerCyaY, the frataxin homolog of Escherichia coli, is known to regulate ISC iron–sulfur cluster assembly through binding to IscS. It also […]
  Paolo Olivieri
• Metal chelation as an antibacterial strategy for Pseudomonas aeruginosa and Acinetobacter baumannii September 23, 2024
  RSC Chem. Biol., 2024, Advance ArticleDOI: 10.1039/D4CB00175C, Review Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Martina M. Golden, Amelia C. Heppe, Cassandra L. Zaremba, William M. WuestA. baumannii and P. aeruginosa pose serious concerns due to heighted multi-drug resistance. A novel method to reduce bacterial virulence and […]
  Martina M. Golden
• A versatile bioluminescent probe with tunable color September 19, 2024
  RSC Chem. Biol., 2024, Advance ArticleDOI: 10.1039/D4CB00101J, Communication Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Zachary R. Torrey, Lila P. Halbers, Lorenzo Scipioni, Giulia Tedeschi, Michelle A. Digman, Jennifer A. PrescherA luciferase-chemogenetic tag fusion was developed for dynamic, multi-color imaging. Unique spectral outputs are observed in the presence […]
  Zachary R. Torrey
• Rapid formation of Nε-(carboxymethyl)lysine (CML) from ribose depends on glyoxal production by oxidation September 17, 2024
  RSC Chem. Biol., 2024, Advance ArticleDOI: 10.1039/D4CB00183D, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Hikari Sugawa, Tsuyoshi Ikeda, Yuki Tominaga, Nana Katsuta, Ryoji NagaiRibose undergoes auto-oxidation and oxidative cleavage between C-2 and C-3 to generate GO and enhance CML accumulation.To cite this article before page numbers are […]
  Hikari Sugawa
• Chemical inhibition of cell surface modification sensitizes bacteria to phage infection September 12, 2024
  RSC Chem. Biol., 2024, Advance ArticleDOI: 10.1039/D4CB00070F, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Marian Aba Addo, Zhiyu Zang, Joseph P. GerdtChemical inhibitor of cell wall alanylation sensitizes bacteria to diverse bacteriophages, revealing the widespread immunity conferred by cell wall modification.To cite this article before page numbers […]
  Marian Aba Addo
• Access to capped RNAs by chemical ligation September 12, 2024
  RSC Chem. Biol., 2024, Advance ArticleDOI: 10.1039/D4CB00165F, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Karolina Bartosik, Ronald MicuraA practical approach to generate mRNA 5′-fragments with clicked triazole linkages in the backbone is presented.To cite this article before page numbers are assigned, use the DOI form of citation […]
  Karolina Bartosik
• Weak effects of prebiotically plausible peptides on self-triphosphorylation ribozyme function September 11, 2024
  RSC Chem. Biol., 2024, Advance ArticleDOI: 10.1039/D4CB00129J, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Joshua T. Arriola, Shayan Poordian, Estefanía Martínez Valdivia, Tommy Le, Luke J. Leman, Joan G. Schellinger, Ulrich F. MüllerFrom a library of 1014 RNA sequences, the strongest benefit of a prebiotically plausible peptide […]
  Joshua T. Arriola
• Improved synthesis of the unnatural base NaM, and evaluation of its orthogonality in in vitro transcription and translation September 10, 2024
  RSC Chem. Biol., 2024, Advance ArticleDOI: 10.1039/D4CB00121D, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Anthony V. Le, Matthew C. T. HartmanIn vitro translation of mRNAs containing the unnatural base pair NaM reveal its orthogonality with native codons.To cite this article before page numbers are assigned, use the […]
  Anthony V. Le