RSC – Food Funct. latest articles- Mechanistic analysis of the association between sugar-sweetened beverages and maternal physiological abnormalities during pregnancy: a gut microbiota-mediated oxidative stress-inflammation network Tháng 3 2, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO05140A, PaperTianle He, Jiaxin Chen, Jundan Zheng, Huifeng Li, Dengjun Ma, Lihong Wang, Jiani Mao, Ju Luo, Zhenguo YangThis study investigates how sugar-sweetened beverages during pregnancy affect maternal metabolism via the gut microbiota, and provides mechanistic evidence for sugar restriction in gestation.To cite this article before page numbers are assigned, […]Tianle He
- Citropten from Citrus sinensis peel protects against obstructive chronic kidney disease: insights from network pharmacology and experimental validation Tháng 3 2, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO05170C, PaperYugant Krishnakumar Talati, Anil Bhanudas GaikwadCitropten from Citrus sinensis peel alleviates renal fibrosis in chronic kidney disease through multi-target modulation, identified by network pharmacology and validated by transcriptomic correlation, molecular docking, and in vivo studies.To cite this article before page numbers are assigned, use the DOI form of citation […]Yugant Krishnakumar Talati
- Resveratrol attenuates high-fat diet-induced testicular injury via the NRF2/GPX4 pathway: an integrated metabolomics and network pharmacology study Tháng 3 2, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO05136C, PaperYating Lai, Yuanyuan Wang, Wei Zeng, Jiayu Zhang, Jiamin Cao, Mengjia Sun, Hongxue Liang, Zhongxiang Zhao, Jing JinRes may exert its protective effects by improving glutathione metabolism and lipid metabolism abnormalities through activation of the NRF2/GPX4 pathway.To cite this article before page numbers are assigned, use the DOI form […]Yating Lai
- Effects of combined phytosterols and phospholipids on blood lipids and the fluidity and lipid profiles of the erythrocyte membrane in individuals with borderline hyperlipidemia: a double-blinded randomized controlled trial Tháng 3 2, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO04992J, PaperLuyao Li, Yuanyuan Huo, Kun Wang, Yulian Sun, Chaoqun Yang, Xin Xu, Chuanxu Zheng, Aiguo Ma, Wei Xu, Jing CaiAfter a 60-day intervention, TC and ApoB decreased significantly in the combined PSs–PLs group, and TC decreased in the PSs-only group. Erythrocyte lipidomics showed associations with blood lipids and membrane […]Luyao Li
- Dietary β-sitosterol alleviates reproductive toxicity induced by combined exposure of low-dose deoxynivalenol and high-fat diet in male C57BL/6J mice Tháng 2 27, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO05222J, PaperYu Zhang, You Zhou, Yilei Lin, Yuanhang Ren, Wenbo Cao, Jun Han, Fei Dong, Gang Wang, Fuhou Li, Shaojie Wu, Shijia Wu, Jianhong XuDietary β-sitosterol can effectively alleviate male reproductive toxicity induced by combined exposure to low-dose deoxynivalenol (DON) and high-fat diet, thereby expanding the nutritional intervention strategy for […]Yu Zhang
- Exploring the neurofunctional potential of saffron bioactives: from mood-related behavioral modulation to brain access of safranal Tháng 2 27, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO04830C, PaperCamille Monchaux de Oliveira, Adeline Vignault, Alexandrine Guille, Sylvie Vancassel, Lucile Capuron, Line Pourtau, Nathalie CastanonDistinct yet complementary actions of saffron bioactives on depression-related pathways, with the first evidence of systemic and brain exposure to safranal.To cite this article before page numbers are assigned, use the DOI form of […]Camille Monchaux de Oliveira
- Comparative evaluation of the short-chain fatty acids formate, propionate, and valerate on intestinal barrier maturation and bone development in neonatal mice Tháng 2 26, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO05394C, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Xue Yang, Xinke Li, Xuan Zhang, Lu Meng, Jiaqi Wang, Nan ZhengShort-chain fatty acids (SCFAs) are key microbial metabolites that support intestinal and skeletal development, yet their coordinated effects during early life remain poorly […]Xue Yang
- Advances in the preparation, characterization and biological activity of food-borne selenium-enriched peptides Tháng 2 26, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO04850H, Review ArticleYing-Chao Qiu, Zi-Ying Zhao, Meng-Jiao Wang, Yinghua ZhangAs a vital trace nutrient for the human body, selenium is essential for many physiological functions. However, the prevalence of selenium insufficiency and associated conditions (such as osteoarthritis and Keshan...The content of this RSS Feed (c) The Royal Society of ChemistryYing-Chao Qiu
- A probiotic from longevity populations: Lactiplantibacillus plantarum FLPL05 as a functional food adjuvant for melanoma via immunomodulation and tumor suppression Tháng 2 25, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO02224J, PaperZhigao Liu, Qi'an Wang, Fangfang You, Yao He, Ke Xie, Hua Wei, Xueying TaoLactiplantibacillus plantarum FLPL05 exhibits anti-melanoma effects through dual (systemic and intratumoral) immunomodulation, tumor apoptosis induction, EMT suppression, and angiogenesis inhibition. Created in https://BioRender.com.To cite this article before page numbers are assigned, use the DOI form of […]Zhigao Liu
- Sea cucumber sulfated fucan protects against acute liver injury in mice: insights from inflammatory responses, gut microbiota and hepatic metabolic profile analyses Tháng 2 25, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO04947D, PaperFeifei Shi, Liting Zheng, Luoyu Wang, Bin Liu, Weiling Guo, Peng LiangAs a natural polysaccharide, sulfated fucan from sea cucumber possesses multiple biological activities, but its protective effect on acute liver injury (ALI) is still unclear.To cite this article before page numbers are assigned, use the DOI form of […]Feifei Shi
- The effect of hemp product consumption on blood fatty acid profiles and cardiovascular disease risk factors: Results of a randomized, double-blind, crossover clinical trial Tháng 2 24, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO04672F, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yongbo She, Kaizhen Jia, Adrianne Cardillo, Maryam Shamloo, Alejandra Serrano León, Xin Liu, Rebecca Mollard, Dylan MacKayHemp seeds are high in polyunsaturated fatty acids (PUFAs) including gamma linolenic acid (GLA), stearidonic acid (SDA), alpha […]Yongbo She
- Comment on “Plant-based diet and risk of arthritis: a nationwide cohort study of the Chinese elderly population” by H. Zhang, J. Liang, Y. Han, J. Tian, Y. Tu, R. Fan, W. Zhu, Z. Zhang and H. Zhao, Food & Function, 2025, 16, 6576 Tháng 2 24, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO05090A, Comment Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Tong Xin, Che Wang, Cuiting Gong, Jingjing He, Xiaoping Wang, Aijing LiuZhang et al. recently reported that higher adherence to plant-based diets was associated with a reduced risk of arthritis in older Chinese adults. […]Tong Xin
- Fu brick tea extracts attenuate HFD induced lipid deposition by regulating the glycerolipid metabolism of gut microbiota and adipose tissue Tháng 2 23, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO05239D, PaperNana Jing, Tong Mu, Xiangyu Bian, Hui Zhao, Qiaoru Li, Zhangmin Chen, Honggang Tang, Jinjun Li, Jinbin Guo, Ke ZhaoFu brick tea (FT), known for regulating lipid metabolism, was studied to explore its lipid-lowering mechanism by analyzing its effects on gut microbes and adipose tissue.To cite this article before […]Nana Jing
- The combination of human milk oligosaccharides 3-fucosyllactose and 3′-sialyllactose alleviates LPS-induced damage to intestinal epithelial cells Tháng 2 23, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO05266A, PaperXianhui Chen, Hao Shi, Mingzhang Zhao, Zhanmei Jiang, Jiahui Guo, Jing Zhang, Xiaolei Duan, He Zhang, Juncai Hou, Xiangyu LiThe combination of 3-fucosyllactose (3-FL) and 3′-sialyllactose(3′-SL) alleviated LPS-induced IEC-6 cell damage by inhibiting the TLR4/NF-κB pathway, promoting the Nrf2/NQO1 pathway, and enhancing intercellular tight junctions.To cite this article before […]Xianhui Chen
- Bilberry (Vaccinium myrtillus L.) Extract Alleviates Gestational Diabetes Mellitus by Coordinating TGR5/FXR Signaling via a Gut Microbiota-Bile Acids Axis Tháng 2 23, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO04882F, PaperShunli Jiang, Qingyue Meng, Chenyun Jiang, Yunzhe Lv, Lingfei Liu, Ruining Xie, Fuli Ya, Qin GaoDietary anthocyanins are associated with a reduced risk of gestational diabetes mellitus (GDM). However, it remains unclear whether their efficacy is mediated through the gut microbiota-bile acids-TGR5/FXR-GLP-1 axis, a mechanism...The content of this RSS […]Shunli Jiang
- Prevention of colorectal cancer and modulation of murine gut microbiota using functional meats Tháng 2 23, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO04442A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Patrick L. McAlpine, Javier Borondo, Mar Grande, Lidia Gil-Martínez, Ana Falcón-Piñeiro, Alberto Baños, Estefanía Crespo Losada, Francisco M. Reyes-Sosa, Miriam Caro Ruiz, Isabel Uribe Oyarbide, María Álvarez Gil, Jesús Fidel Delgado Ramallo, Ana Martín […]Patrick L. McAlpine
- Kaempferol Alleviates Right Ventricular Hypertrophy in High Altitude Pulmonary Hypertension Rats by Modulating AMPK/ACC/CPT1B Axis and AMPK-mediated LDHA/PDHA1 Pathway Tháng 2 20, 2026Food Funct., 2026, Accepted ManuscriptDOI: 10.1039/D5FO04265H, PaperQiongqiong Zhao, Shanshan SU, Chen Ju, Meiduo Huayu, Xingmei Nan, Xiaoping Li, Zhanqiang Li, Dianxiang LuTo evaluate the effect of Kaempferol on right ventricle (RV) structure/function in high-altitude pulmonary hypertension (HAPH) rats and to explore the underlying mechanisms. Methods: Male Sprague-Dawley rats (n=57) were exposed...The content of this RSS […]Qiongqiong Zhao
- Flavonoids and polycystic ovary syndrome Tháng 2 19, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO04823K, Review ArticleHao Shen, Yu LiuPCOS is characterized by oxidative stress, inflammation, and insulin resistance, which are key therapeutic targets of flavonoids.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of ChemistryHao Shen
- Fructooligosaccharide ameliorates estrogen–gut–microbiome–brain axis dysfunction in estrogen-deficient rats Tháng 2 19, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO03823E, PaperRishabh Chaudhary, Nitin Bansal, Roshan Lal, Amanpreet Kaur, Mahendra Bishnoi, Kanthi Kiran Kondepudi, Kanwaljit Chopra, Seema BansalEstrogen deficiency after ovariectomy causes gut and brain deficits. To date, 17β-estradiol, has been used for postmenopausal complications. Thus, our aim was to find novel solutions that may improve postmenopausal gut–brain axis dysfunction.To […]Rishabh Chaudhary
- Fava bean and pea protein hydrolysates modulate stress responses in C. elegans through different mechanisms Tháng 2 18, 2026Food Funct., 2026, Advance ArticleDOI: 10.1039/D5FO04100G, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Maialen Uriz-Martínez, Diana Ansorena, Iciar Astiasaran, David Muñoz-Prieto, Ana Isabel Yetano, Carolina González-Ferrero, Paula AranazThe growing global demand for protein, combined with the need for effective strategies to manage conditions such as obesity and […]Maialen Uriz-Martínez
- Mechanistic analysis of the association between sugar-sweetened beverages and maternal physiological abnormalities during pregnancy: a gut microbiota-mediated oxidative stress-inflammation network Tháng 3 2, 2026
