RSC – Nat. Prod. Rep. latest articles- Progress, challenges, and opportunities in the field of biosynthetic reactions involving ambimodal transition states Tháng mười một 18, 2025Nat. Prod. Rep., 2025, Advance ArticleDOI: 10.1039/D5NP00064E, HighlightHidayat Hussain, K. N. Houk, Ching Ching Lam, Satyajit D. Sarker, Lutfun NaharThis review describes enzyme-catalyzed reactions involving ambimodal transition states, and recent advances in understanding how enzymes control selectivity in such reactions.To cite this article before page numbers are assigned, use the DOI form of citation above.The […]Hidayat Hussain
- AI and mechanistic modeling for characterizing biosynthetic pathways of natural products Tháng mười một 7, 2025Nat. Prod. Rep., 2025, Advance ArticleDOI: 10.1039/D5NP00059A, HighlightByung Tae Lee, Byeongsub Lee, Joon Young Kwon, Tilmann Weber, Hyun Uk KimIntegrating AI-driven and mechanistic modeling accelerates the discovery and engineering of natural product biosynthetic pathways.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) […]Byung Tae Lee
- Glycosylated mycotoxins: a hidden enemy Tháng mười một 3, 2025Nat. Prod. Rep., 2025, Advance ArticleDOI: 10.1039/D5NP00057B, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Milena Stránská, Tomáš Řezanka, Vladimír KřenComprehensive review of glycosylated mycotoxins in the food chain: their formation, analytical challenges, health effects and toxicology, synthetic methods, deglycosylation strategies, and regulatory aspects.To cite this article […]Milena Stránská
- Halogenases and dehalogenases: mechanisms, engineering, and applications Tháng mười một 3, 2025Nat. Prod. Rep., 2025, Advance ArticleDOI: 10.1039/D5NP00055F, Review ArticleJing Luo, Na Li, Jia Wang, Yaojie Gao, Hongzhi Tang, Linquan Bai, Sang Yup Lee, Yaojun TongHalogenases and dehalogenases are ubiquitous biocatalysts that mediate halogen incorporation and removal. Synthetic biology is reshaping their catalytic landscapes to unlock new functions and applications.To cite this article before page numbers […]Jing Luo
- Metabolism and bioavailability aspects of natural products of plant origin using mass spectrometry-based and metabolomic approaches Tháng 10 28, 2025Nat. Prod. Rep., 2025, Advance ArticleDOI: 10.1039/D5NP00022J, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Eleni V. Mikropoulou, Aikaterini Basdeki, Maria HalabalakiThis review investigates the journey of metabolite identification and quantification of natural products (NPs), exploiting mass spectrometry approaches from the early 1980s to the current developments […]Eleni V. Mikropoulou
- Correction: Unpacking policy developments in marine natural product research: a scientist's guide to DSI and BBNJ Tháng 10 8, 2025Nat. Prod. Rep., 2025, 42,1909-1909DOI: 10.1039/D5NP90039E, Correction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Federica Casolari, Amelia Westmoreland, Thomas Vanagt, Marcel JasparsThe content of this RSS Feed (c) The Royal Society of ChemistryFederica Casolari
- Biosynthesis of biologically active terpenoids in the mint family (Lamiaceae) Tháng 8 26, 2025Nat. Prod. Rep., 2025, 42,1887-1908DOI: 10.1039/D5NP00026B, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Maximilian Frey, Sandra T. Gohr, Tobias G. Köllner, Ulschan Bathe, Nathalie D. Lackus, Federico Padilla-Gonzalez, Dae-Kyun Ro, Sarah E. O'Connor, Jörg Degenhardt, Alain TissierThe mint family (Lamiaceae) produces a wide range of bioactive […]Maximilian Frey
- Natural products influence bacteriophage infectivity Tháng 8 17, 2025Nat. Prod. Rep., 2025, 42,1849-1886DOI: 10.1039/D5NP00014A, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Zhiyu Zang, Joseph P. GerdtThis review comprehensively reports historical and recent examples of natural products that either prevent bacteriophages from infecting bacteria, promote those infections, or regulate the induction of the lytic cycle […]Zhiyu Zang
- Coprophilous fungi in the search for new antimicrobials and other beneficial natural products Tháng 8 7, 2025Nat. Prod. Rep., 2025, 42,1835-1848DOI: 10.1039/D5NP00015G, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Esteban Charria-Girón, Joseph Tchamgoue, Marc Stadler, Yasmina Marin-FelixThis review focuses on the chemical diversity of secondary metabolites produced by coprophilous fungi, i.e. those that inhabit or are associated with animal dung, with particular […]Esteban Charria-Girón
- Microbial engineering for natural and unnatural glycosaminoglycans biosynthesis Tháng 8 4, 2025Nat. Prod. Rep., 2025, 42,1811-1834DOI: 10.1039/D5NP00043B, Review ArticleChunlei Zhao, Jinyi Qian, Xiulai ChenThis review outlines how microbial engineering enables sustainable production of natural and unnatural glycosaminoglycans, replacing conventional chemical methods.The content of this RSS Feed (c) The Royal Society of ChemistryChunlei Zhao
- Recent progress of [5 + 2] cycloaddition reactions in natural product synthesis Tháng 7 27, 2025Nat. Prod. Rep., 2025, 42,1755-1785DOI: 10.1039/D5NP00023H, Review ArticleNan Wang, Yu Bai, Qingyi Zeng, Tao Zhang, Jun DengA systematic review of three major types of [5 + 2] cycloaddition reactions in natural product synthesis (2013–2024), highlighting their power in constructing complex frameworks through direct comparisons with alternative synthetic strategies.The content of this RSS Feed (c) The […]Nan Wang
- Spiroketal natural products isolated from traditional Chinese medicine: isolation, biological activity, biosynthesis, and synthesis Tháng 7 20, 2025Nat. Prod. Rep., 2025, 42,1786-1810DOI: 10.1039/D5NP00035A, Review ArticleEilidh G. Young, Freda F. Li, Margaret A. BrimbleIn this review, we examine the origins and synthesis of bioactive spiroketal-containing natural products isolated from traditional Chinese medicines.The content of this RSS Feed (c) The Royal Society of ChemistryEilidh G. Young
- Progress, challenges, and opportunities in the field of biosynthetic reactions involving ambimodal transition states Tháng mười một 18, 2025