RSC – Org. Biomol. Chem. latest articles
- Highly Enantio- and Diastereoselective Construction of Spirocyclic Oxindoles via a Palladium-Catalyzed Decarboxylative Asymmetric [4 + 2] Annulation Strategy Tháng Tư 30, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00518J, CommunicationPengyuan You, Minjie Liu, Ke Zhang, Fan Yang, Zequn Tan, Fener ChenA palladium-catalyzed decarboxylative asymmetric [4 + 2] annulation of methyleneindolinones with a zwitterionic oxo-1,4-dipole intermediate was successfully developed to access spirocyclic oxindoles bearing two vicinal stereocenters in good yields with...The content of this RSS Feed (c) The […]Pengyuan You
- Photocatalytic C2-Trifluoroethylation and Perfluoroalkylation of 3-Substituted Indoles Using Fluoroalkyl Halides Tháng Tư 30, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00392F, CommunicationShivani Arora, Tavinder Singh, Anand SinghA photocatalytic reactivity platform for the C2-trifluoroethylation and perfluoroalkylation of 3-substituted indoles has been developed. A range of fluoroalkyl halides have been employed as radical precursors under mild, transition-metal-free conditions...The content of this RSS Feed (c) The Royal Society of ChemistryShivani Arora
- Development of 18F-Labeled Azobenzothiazole Tracer for α-Synuclein Aggregates in the Brain Tháng Tư 30, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00492B, PaperJiajun Wu, Meiting Mao, Jie Yang, Kexin Li, Pengxin Deng, Jing Zhong, Xiaoai Wu, Yan ChengNuclear imaging of aggregated α-synuclein pathology is in urgent clinical need for Parkinson’s disease, yet promising tracers for brain α-synuclein aggregates are still rare. In this work, a class of...The content of this […]Jiajun Wu
- Borrowing Hydrogen C-alkylation with secondary saturated heterocyclic alcohols Tháng Tư 30, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00543K, PaperJordan François, Maiwenn Jacolot, Florence PopowyczThe borrowing hydrogen methodology (BH) has emerged as a powerful tool for the rapid construction of C-C bonds, offering a greener alternative to traditional multi-step syntheses. This methodology involves the...The content of this RSS Feed (c) The Royal Society of ChemistryJordan François
- Lewis acid catalyzed Markovnikov hydrobromination and hydrochlorination of alkynes using TMSX (X = Br, Cl) Tháng Tư 30, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00608A, CommunicationDalong Shen, Dehai Cao, Ruizeng Zhang, Peiyuan Bai, Zhenxing LiuThe Markovnikov hydrobromination and hydrochlorination of alkynes were achieved using TMSX (X = Br, Cl) instead of corrosive HX (X = Br, Cl) as the bromination and chlorination reagents. Mn(OAc)2.4H2O...The content of this RSS Feed (c) The Royal Society […]Dalong Shen
- Practical Synthesis of Isoindolines Yields Potent Colistin Potentiators in Multidrug-Resistant Acinetobacter baumannii Tháng Tư 30, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00463A, CommunicationSomnath Dutta, Samantha Eyolfson, Yuhang Zhou, Yuefeng Gao, Xiang WangAn efficient and practical one-pot synthesis of isoindolines from readily available starting materials was achieved under mild conditions by implementing isoindole umpolung strategy. A variety of isoindolines were prepared with...The content of this RSS Feed (c) The Royal Society […]Somnath Dutta
- Supramolecular electrochemical probe based on the system of tetrazole derivative pillar[5]arene/methylene blue Tháng Tư 29, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00591K, PaperLaysan Makhmutova, Dmitriy Shurpik, Olga Mostovaya, Natalia Lachugina, Alexander Gerasimov, Adelya Guseinova, Gennady Evtugyn, Ivan StoikovFor the first time, an original synthetic approach has been developed that makes it possible to introduce ten tetrazole fragments into the pillar[5]arene structure. A supramolecular electrochemical probe was assembled...The content of this […]Laysan Makhmutova
- Electrochemical Benzylic Deuteration of p-QMs Enabling the Synthesis of Benzylic Deuterated Diarylmethanes Tháng Tư 29, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00537F, CommunicationYunying Yan, Jianjun Hao, Yulin Peng, Mengyun Yin, Linhai Jing, Pan HanHerein, electroreductive umpolung benzylic deuteration of p-QMs using cheap and easily accessible D2O as a deuterium source was realized. Various value-added benzylic deuterated diarylmethanes can be synthesized without the requirement...The content of this RSS Feed (c) The […]Yunying Yan
- Metal- and Photocatalyst-Free Approach to Visible-Light-Induced Acylation of Quinoxalinones. Tháng Tư 29, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00630E, PaperWorawat Niwetmarin, Naiyana Saesian, Rungroj Saruengkhanphasit, Chatchakorn Eurtivong, Nopporn Thasana, Somsak RuchirawatA transition-metal- and photocatalyst-free photochemical reaction was successfully developed for the direct acylation of quinoxalin-2(1H)-ones, which was enabled by the formation of electron donor-acceptor (EDA) complexes. The use of DBU...The content of this RSS Feed (c) The […]Worawat Niwetmarin
- Visible-Light-Induced Three-Component Reactions of α-Diazoesters, Quinazolinones and Cyclic Ethers Selectively Lead to Quinazoline-Based Hybrids Tháng Tư 29, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00295D, PaperYiyuan Peng, Yan Liu, Qin Yang, Wei Wang, Yang Fu, Qiuping DingAn effective approach for the construction of 4-short-chain ether attached carbonyl group-substituted quinazolines was developed. The visible-light-induced three-component reactions of α-diazoesters, quinazolinones, and cyclic ethers, with broad substrate scope and...The content of this RSS Feed (c) The […]Yiyuan Peng
- Structure and isomerization behavior relationships of new push–pull azo-pyrrole photoswitches Tháng Tư 29, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00417E, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.David Gallardo-Rosas, José Manuel Guevara-Vela, Tomás Rocha-Rinza, Ruben Alfredo Toscano, Jose G. López-Cortés, M. Carmen Ortega-AlfaroA new family of stilbenyl-azopyrroles compounds 2a-d and 3a–d was efficiently obtained via a Mizoroki-Heck C-C-type coupling reaction […]David Gallardo-Rosas
- Photoinduced metal-free trifluoro/perfluoroalkylation of heteroarenes Tháng Tư 28, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00511B, CommunicationRavi Prakash Singh, Shashank SinghA practical and straightforward protocol to access trifluoromethylated/perfluoroalkylated heteroarenes via radical type nucleophilic substitution rather than typical radical type electrophilic substitution is described here. The substrate scope was observed to...The content of this RSS Feed (c) The Royal Society of ChemistryRavi Prakash Singh
- Antimicrobial sesterterpenoids with a unique 5/8/6/5 tetracyclic carbon-ring-system and diepoxide polyketides from a deep sea-sediment-sourced fungus Chaetomium globosum SD-347 Tháng Tư 28, 2024Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00449C, PaperXiao-Dong Li, Xiao-Ming Li, Bin-Gui Wang, Xin LiTwo new tetracyclic sesterterpenoids and two new diepoxide polyketides with antimicrobial activity were characterized from the culture extract of Chaetomium globosum SD-347, a fungal strain derived from deep sea-sediment.To cite this article before page numbers are assigned, use the DOI form […]Xiao-Dong Li
- BPO-Promoted [4 + 2] cyclization of enaminones and o-phenylenediamines to 2-acyl quinoxalines via a cascade transamination and C–H amination Tháng Tư 28, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00494A, CommunicationHeng Feng, Jie Hou, Xiaonan Mu, Renhua Zheng, Xiao Geng, Lei WangRapid assembly of quinoxalines in a single step from easily available precursors have been recognized as an ideal platform in term of efficiency and operation. Herein, we report a BPO-promoted...The content of this RSS Feed (c) The […]Heng Feng
- PIDA-Promoted metal-free [3 + 2] heteroannulation of β-ketothioamides with 4-hydroxy coumarins: chemo-/regioselective access to furo[3,2-c]chromen-4-ones at room temperature Tháng Tư 28, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00438H, PaperAnup Kumar Yadav, Dhananjay Yadav, Vipin Kumar, Subhasish Ray, Maya Shankar SinghHerein, we report a viable protocol to access furo[3,2-c]chromen-4-ones engaging easily accessible 4-hydroxy coumarins as a three-atom CCO unit and thioamides as a C2 coupling partner mediated by phenyliodine(III) diacetate...The content of this RSS Feed (c) The […]Anup Kumar Yadav
- Development of an efficient and scalable bioprocess for the plant hormone 12-OPDA: Overcoming hurdles of nature´s biosynthesis Tháng Tư 28, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00258J, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Tim Guntelmann, Karl-Josef Dietz, Harald GrögerBesides its native biological function as plant hormone, cis-(+)-12-oxo-phytodienoic acid (12-OPDA) serves as a metabolite for the cellular formation of (-)-jasmonic acid and also turned out to have […]Tim Guntelmann
- Copper(II) nanodots stabilized on Cassia fistula galactomannan: preparation and catalytic application towards fast solvent-free Biginelli reactions Tháng Tư 25, 2024Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00441H, PaperBal Dev Singh, Jyoti Pandey, Huda Khanam, Bhoopendra Tiwari, Tazeen Azeez, Ayushi Mishra, Preeti KanchanNew Cu(II) nanodots have been developed using biopolymeric polysaccharide galactomannan.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society […]Bal Dev Singh
- Visible-light-induced C(sp3)-H bromination of 4-methylthiophene derivatives with HBr/H2O2 Tháng Tư 25, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00547C, PaperWenbo Song, Ming Ma, Wenjing Zhang, Cong-Cong Lu, Ranran Feng, Hong-Yu Zhang, Yuecheng Zhang, Jiquan ZhaoA convenient method to synthesize ethyl 4-(bromomethyl)thiophene-3-carboxylate derivatives has been developed via visible-light-induced radical processe with good yields and a wide range of functional group tolerance under air and ambient...The content of this […]Wenbo Song
- Efficient and Scalable Synthesis of 3,4-Dihydroisoquinolin-1(2H)-ones by Benzylic Oxidation of Tetrahydroisoquinoline Derivatives using Cerium Ammonium Nitrate (CAN) Tháng Tư 25, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00491D, PaperJiajun Luo, Zhilong Li, Jiaxin He, Tong Li, Daochen Wu, Yang Lai, Haiying SunHerein, we report an efficient method for the synthesis of 3,4-dihydroisoquinolin-1(2H)-ones by oxidation of tetrahydroisoquinoline derivatives using cerium ammonium nitrate (CAN) and NaBrO3.The content of this RSS Feed (c) The Royal Society of ChemistryJiajun Luo
- Pd(II)/LA-catalyzed acetanilide olefination with dioxygen Tháng Tư 25, 2024Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00468J, PaperKaiwen Li, Shuangfeng Dong, Shuang-Long Li, Zhuqi Chen, Guochuan YinTransition-metal-catalyzed aromatic olefination through direct C-H activation represents an atom and step-economic route for versatile pharmaceutical syntheses, and in many cases, different stoichiometric oxidants were frequently employed for achieving a...The content of this RSS Feed (c) The Royal Society […]Kaiwen Li
- Highly Enantio- and Diastereoselective Construction of Spirocyclic Oxindoles via a Palladium-Catalyzed Decarboxylative Asymmetric [4 + 2] Annulation Strategy Tháng Tư 30, 2024