RSC – Lab Chip latest articles- Sequential trench well based microfluidic platform to isolate bacteria from whole blood with large volume processing Tháng 10 31, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00931F, PaperCheonggyu Lee, Gi Yoon Lee, hyelyn Joo, Hamin Kim, Junwon Kang, Tae Hyun Kim, Jonghyun Ha, Sunghoon Kwon, Jungil ChoiThe separation of bacteria from infected blood is a crucial step for downstream bacterial detection and analysis. However, the extremely low bacterial concentration and high proportion of blood cells present...The […]Cheonggyu Lee
- Development of a lab-on-a-chip device for optimising CPA delivery in human oocyte vitrification Tháng 10 29, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D4LC00978A, PaperAli Hassanpour Lima, Hadi Veladi, Masoud MalekiCryopreservation of reproductive cells, including sperms, oocytes, and embryos, has become a vital practice in contemporary medicine, especially for patients undergoing treatments like chemotherapy that may impair fertility.To cite this article before page numbers are assigned, use the DOI form of citation above.The […]Ali Hassanpour Lima
- Immune-integrated cardiac fibrosis-on-a-chip: a 3D microfluidic device for region–specific immune–cardiac crosstalk in the fibrotic heart Tháng 10 29, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00469A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jiaying Ji, Mateo Tristan, Frank Ketchum, Wenzheng Kuang, Guosheng Fu, Xiang Ren, Pinar ZorlutunaWe engineered a cardiac fibrosis-on-a-chip using iPSC-derived cardiomyocytes and fibroblasts with localized macrophage delivery to model post-MI remodeling. This platform enables […]Jiaying Ji
- Transforming microfluidics for single-cell analysis with robotics and artificial intelligence Tháng 10 28, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00216H, Critical Review Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jinxiong Cheng, Rajiv Anne, Yu-Chih ChenSingle-cell analysis has advanced biomedical research by revealing cellular heterogeneity with unprecedented resolution, identifying rare subpopulations that drive disease progression and therapeutic resistance. Microfluidics is central to this […]Jinxiong Cheng
- A Novel Alveoli-on-Chip Platform for Modeling Cyclic Stretch in Patient-Derived Alveolar Epithelial Cells Cultured from Organoids Tháng 10 23, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00473J, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Mohammad Amin Hajari, Jan Schulte, Dario Principi, Damian Schnidrig, Sabine Schneider, Tobias Weber, Joo-Hyeon Lee, Patrick Dorn, Pauline Zamprogno, Thomas M. Marti, Olivier T. GuenatWe report a novel alveoli-on-chip (AOC) platform that replicates an […]Mohammad Amin Hajari
- Behaviorome profiling of anti-tumor and pro-tumor human neutrophil subtypes in a microphysiological system Tháng 10 23, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00526D, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Shuai Shao, Daniel Duncko, Caroline N. JonesOn-chip behaviorome mapping of anti-tumor and pro-tumor human neutrophil subtypes.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this […]Shuai Shao
- Establishment of an Ultrasound Responsive Microfluidic Chip of BBB-Glioblastoma model for Studying Sonodynamic Therapy-enhanced Nanodrug Delivery Tháng 10 23, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00799B, PaperLiyang Wu, Bingcheng Lin, Huadong Fan, Yihong LiGlioblastoma (GB), the most common primary malignant brain tumor, faces limited treatment efficacy due to Blood-Brain-Barrier (BBB) restricting drug delivery. Sonodynamic therapy (SDT) presents a promising non-invasive alternative, using ultrasound...The content of this RSS Feed (c) The Royal Society of ChemistryLiyang Wu
- Hydrophilic Skin-Interfaced Microfluidic Devices for Comprehensive Sweat Collection and Analysis Tháng 10 23, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00703H, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Fina Lu, Ji Hyun Yang, Ahyeon KohBlood and interstitial fluids are standard biofluids for clinical assessments. Despite their rich analyte content, the adaptation of bioanalysis in wearable devices is limited by the requirement for […]Fina Lu
- Microfluidic device for islet conformal coating with a polyethylene glycol-based hydrogel: innovating cell immunoprotection strategies in type 1 diabetes Tháng 10 22, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00690B, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Francesca Vicinanza, Tatiana Mencarini, Francesca Verderio, Grisell C. Gonzalez, Helena Montuoro, Silvia Bozzi, Ashutosh Agarwal, Marco Rasponi, Alberto Redaelli, Alice A. TomeiOur microfluidic platform enables the conformal coating of insulin-secreting clusters for scalable, high-precision […]Francesca Vicinanza
- Microneedle patch integrated with a pumpless microfluidic chip for heterologous drug delivery Tháng 10 22, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D4LC00864B, PaperJi Won Park, Hye Jin Choi, Min Chul Shin, Bo Hyun Kim, Gyu Man KimSchematic of the drug release (a) from MN patches by a general surface coating method and (b) from the MN patch with a hole combined with a microfluidic chip.To cite this article before page numbers […]Ji Won Park
- Sequencing-free, joint single-EV profiling of DNA and protein cargos enables accurate cancer detection at early stages Tháng 10 22, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00661A, PaperYufeng Jiao, Luxuan Yao, Wenqing Zeng, Kaiyan Hao, Taotao Dong, Yawen Zheng, Si-Yang Zheng, Wu LiuColocalization of DNA and protein markers reveals rare extracellular vesicle subpopulations for facile and affordable cancer diagnosis at early stages.To cite this article before page numbers are assigned, use the DOI form of citation […]Yufeng Jiao
- Manipulation and 3D characterization of particles and cells through integrated light field microscopy and droplet microfluidics system Tháng 10 20, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00641D, PaperXinglong Huang, Jiayan Zhuang, Rifei Chen, Yingzhen Piao, Boris Stoeber, Xing ChengThis work integrates a droplet microfluidics platform with a novel bifocal MLA-based light field microscopy system, enabling precise droplet manipulation and 3D imaging and tracking of dynamic biological samples in microchannels.To cite this article before page numbers are […]Xinglong Huang
- Enhancing cancer therapy via acoustics: chemotherapy-enhanced tunable acoustofluidic permeabilization (ChemoTAP) Tháng 10 20, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00419E, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Ruoyu Zhong, Ke Li, Kaichun Yang, Qian Wu, John D. H. Mai, Joseph Rich, Ying Chen, Xianchen Xu, Jianping Xia, Neil Upreti, Ke Jin, Shujie Yang, Mingyuan Liu, Tony Jun HuangA chemo-acoustic tumor stimulation […]Ruoyu Zhong
- Microengineered diabetic wound-on-a-chip model for emulating chronic wound dynamics Tháng 10 16, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00500K, PaperShivam Sharma, Anil KishenA tri-cellular diabetic wound-on-a-chip model reproduces hyperglycemia/AGEs/LPS-induced inflammation, impaired ECM remodeling, reduced angiogenesis and EndMT, offering a human-relevant platform for mechanistic and preclinical investigations.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The […]Shivam Sharma
- Active droplet generation in flow-focusing microfluidics under influence of transverse magnetic field Tháng 10 15, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00805K, PaperBoris Kichatov, Vladimir Sudakov, Dariya Kalyuzhnaya, Alexey Korshunov, Petr RyapolovMagnetic fields can be used to control the process of magnetic fluid dispersion in microfluidics.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of […]Boris Kichatov
- A luminescence-based point-of-care HIV viral load test for antiretroviral therapy monitoring Tháng 10 15, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00636H, PaperSungwan Kim, Hak-Rae Hong, Jong-Min Oh, Juhyeon Chun, Adharsh Chellappaa, Jungmin Yoo, Syed Maaz Husain, Jaebaek Lee, Jisan Kim, Prudhvi Thirumalaraju, Younseong Song, Manoj K. Kanakasabapathy, Juyong Gwak, Joseph M. Hardie, Daniel R. Kuritzkes, Jonathan Z. Li, Athe M. Tsibris, Hadi ShafieeA low-cost, automated device delivers a qualitative HIV […]Sungwan Kim
- A multi-valve centrifugal microfluidic for Mycoplasma pneumoniae detection Tháng 10 15, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00667H, PaperGuangyao Chen, Yu Lu, Hao Shen, Jing Zhang, Yizhu Liu, Liwei Xue, Liguo ChenIntegrated detection process based on centrifugal microfluidic chips.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of ChemistryGuangyao Chen
- Embroidered paper-based electrochemical wearable device for pH monitoring in wounds Tháng 10 14, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00609K, PaperLaura Belcastro, Luca Fiore, HIMA ZAFAR, Mitar Simic, Raffaele Vitiello, Marco Libertini, Florigio Lista, Giulio Maccauro, Goran M Stojanović, Fabiana ArduiniHerein, we reported the first microfluidic thread/paper-based analytical electrochemical device (μTPAD) by harnessing the synergic combination of embroidery as a manufacturing technique and paper-based technology. The effectiveness of the […]Laura Belcastro
- OpenLM: an open-source pixel super-resolution platform for lens-free microscopy with applications in bacterial growth monitoring and deep learning-based bacterial detection Tháng 10 14, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00719D, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Weiming Xu, Samiha Ahmed, Majed Althumayri, Azra Yaprak Tarman, Mert Kerem Ulku, Karston Yong, Muhammed Veli, Hatice Ceylan KoydemirOpenLM is a low-cost, open-source lens-free microscopy system that uses a pixel super-resolution algorithm and simple […]Weiming Xu
- Design, fabrication, and characterization of a microbubble array microphysiological system Tháng 10 13, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00411J, PaperLukas B. Jenkins, Hasibul Hasan Hredoy, Hossein Abolhassani, Chiao Yun Chen, Michelle Duan, Lisa A. DeLouiseMicrobubble (MB) technology is uniquely suited for integration into microphysiological systems (MPS) for high throughput three-dimensional (3D) tissue culture, drug screening and toxicity testing.To cite this article before page numbers are assigned, use the […]Lukas B. Jenkins
- Sequential trench well based microfluidic platform to isolate bacteria from whole blood with large volume processing Tháng 10 31, 2025
