RSC – Chem. Sci. latest articles- Computational Discovery and Systematic Analysis of Protein Entangling Motifs in Nature: From Algorithm to Database Tháng 3 30, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D4SC08649J, Edge Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Puqing Deng, Yuxuan Zhang, Lianjie Xu, Jinyu Lyu, Linyan Li, Fei Sun, Wen-Bin Zhang, Hanyu GaoNontrivial protein topology has potential to revolutionize protein engineering by enabling the manipulation of proteins’ stability and dynamics. […]Puqing Deng
- Tuning the Modal Coupling in Three-Dimensional Au@Cu2O@Au Core-Shell-Satellite Nanostructure for Enhanced Plasmonic Photocatalysis Tháng 3 30, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC00610D, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Qingfeng Zhang, Lichao Sun, Yahui Yang, Binbin Zhang, Xuehao Sun, Yunlong Tao, Guizeng Yang, Chuang Liu, Zixu WangThe fascinating optical properties of coupled plasmonic nanostructures have attracted great attention and emerged as a […]Qingfeng Zhang
- Biosynthesis of the tetrahydroxynaphthalene-derived meroterpenoid furaquinocin via reductive deamination and intramolecular hydroalkoxylation of an alkene Tháng 3 30, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D4SC08319A, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Tomohiro Noguchi, Fan Zhao, Yoshitaka Moriwaki, Hideaki Yamamoto, Kei Kudo, Ryuhei Nagata, Takeo Tomita, Tohru Terada, Kentaro Shimizu, Makoto Nishiyama, Tomohisa KuzuyamaHybrid isoprenoid-polyketides, known as meroterpenoids, are a family of natural products that […]Tomohiro Noguchi
- Coordination-Driven Assembly of a Ferrocene-Functionalized Lead Iodide Framework with Enhanced Stability and Charge Transfer for Photocatalytic CO2-to-CH3OH Conversion Tháng 3 30, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D4SC08216H, Edge Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Jinlin Yin, Yani He, Chen Sun, Yilin Jiang, Honghan FeiHybrid lead halides are promising photocatalysts due to high structural tunability and excellent photophysical properties, but their ionic structures suffer from instability in polar […]Jinlin Yin
- An Implantable Ionic Liquid-Gel Microelectrode for In Vivo Monitoring of K+ Levels in the Living Rat Brain Tháng 3 30, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC01609F, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Zhihui Zhang, Zehui Chen, Tao Liu, Limin ZhangThe exploration of new interfaces for in vivo analysis holds great promise for electrochemical acquirement of chemical signals involved in brain events. In this study, we […]Zhihui Zhang
- Biocatalytic recycling of plastics: facts and fiction Tháng 3 30, 2025Chem. Sci., 2025, Advance ArticleDOI: 10.1039/D5SC00083A, Perspective Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Wolfgang ZimmermannEnzymatic recycling of plastic waste is attracting considerable attention as a novel strategy to advance a circular plastic economy. While currently limited to polyesters, achieving economically viable biocatalytic processes remains a key challenge.To […]Wolfgang Zimmermann
- Do weaker solvation effects mean better performance of electrolytes for lithium metal batteries? Tháng 3 30, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC01495F, Edge Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Liang Li, Kaixiang Ren, Wenjun Xie, Qi Yu, Shilin Wu, Hai-Wen Li, Meng Yao, Zhipeng Jiang, Yongtao LiThe design of novel electrolytes is crucial for ensuring the practical application of high-voltage lithium metal […]Liang Li
- A method to identify small molecule/protein pairs susceptible to protein ubiquitination by the CRBN E3 ligase Tháng 3 30, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC01251A, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Pinwen Cai, Chiara Disraeli, Basilius Sauter, Saule Zhanybekova, Dennis GillinghamAlthough using DNA-encoded libraries (DELs) to find small molecule binders of target proteins is well-established, identifying molecules with functions beyond binding remains challenging in […]Pinwen Cai
- IMPRESSION Generation 2 – Accurate, fast and generalised neural network model for predicting NMR parameters in place of DFT. Tháng 3 30, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D4SC07858F, Edge Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Calvin Yiu, Ben Honoré, Will Gerrard, Jose Napolitano, Dave Russell, Iuni Margaret Laura Trist, Ruth Dooley, Craig Philip ButtsPredicting 3D-aware Nuclear Magnetic Resonance (NMR) properties is critical for determining the 3D structure and […]Calvin Yiu
- Genetically Encoded 3-Aminotyrosine as Catalytic Residue in a Designer Friedel-Crafts Alkylase Tháng 3 30, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC01055A, Edge Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Bart Brouwer, Franco Della Felice, Andy-Mark Thunnissen, Gerard RoelfesGenetic incorporation of noncanonical amino acids (ncAAs) harbouring catalytic side chains into proteins allows the creation of enzymes able to catalyse reactions that have no […]Bart Brouwer
- Polymerization-induced self-assembly enables access to diverse highly ordered structures through kinetic and thermodynamic pathways Tháng 3 30, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC01703C, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Ibuki Shibata, Ayae Sugawara-Narutaki, Rintaro TakahashiPolymerization-induced self-assembly (PISA) has emerged as a powerful technique for generating microphase-separated structures, but research has primarily focused on systems exhibiting “disordered” structures. Here, we demonstrate the facile […]Ibuki Shibata
- SIM Imaging of Bacterial Membrane Dynamics and Lipid Peroxidation During Photodynamic Inactivation with a Dual-Functional Activatable Probe Tháng 3 30, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC00858A, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yi Tao, Qinglong Qiao, Yiyan Ruan, Xiangning Fang, Xiang Wang, Yinchan Zhang, Pengjun Bao, Yalin Huang, Zhaochao XuPhotodynamic inactivation (PDI) has emerged as a promising antibacterial strategy that mitigates the risk of bacterial […]Yi Tao
- Chemoproteomic identification of phosphohistidine acceptors: Posttranslational activity regulation of a key glycolytic enzyme Tháng 3 30, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC01024A, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Solbee Choi, Seungmin Ahn, Kyung Hyun Cho, Sung Kuk Lee, Jung-Min KeeHistidine phosphorylation, an unconventional and understudied posttranslational modification, often involves phosphohistidine (pHis) “acceptor” proteins, which bind to pHis residues and undergo phosphotransfer […]Solbee Choi
- Chiral Ring-in-Ring Complexes with Torsion-Induced Circularly Polarized Luminescence Tháng 3 28, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC00624D, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jia Liu, Xiujie Han, Xin Wen, Hao Yu, Bao Li, Ming Wang, Minghua Liu, Guanglu WuWe introduce a class of supramolecular precursors, termed ‘folda-bonders’, which utilize macrocycles to fold and precisely align reactive […]Jia Liu
- Sustainable and cost-effective electrode manufacturing for advanced lithium batteries: the roll-to-roll dry coating process Tháng 3 28, 2025Chem. Sci., 2025, Advance ArticleDOI: 10.1039/D5SC00059A, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Joonhyeok Park, Jiwoon Kim, Jaeik Kim, Minsung Kim, Taeseup Song, Ungyu PaikThis review highlights the roll-to-roll dry coating process, a scalable and industrially viable approach, by introducing its underlying mechanisms, latest developments, and […]Joonhyeok Park
- Boosting Ru Atomic Efficiency of LaFe0.97Ru0.03O3 via Knowledge-Driven Synthesis Design Tháng 3 28, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC00778J, Edge Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Yu Wang, Paul Paciok, Lukas Pielsticker, Alexander Spriewald Luciano, Lorena Glatthaar, Aijie Xu, Zimo He, Min Ding, Walid Hetaba, Jaime Gallego, Yanglong Guo, Bernd Smarsly, Herbert OverThe exsolution of ruthenium from a 3 […]Yu Wang
- Organocatalytic Atroposelective De Novo Construction of Monoaxially and 1,4-Diaxially Chiral Fused Uracils with Potential Antitumor Activity Tháng 3 28, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC00452G, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yuzhi Ren, Lin Chen, Han Zhang, Zuquan Liu, Donghui Wei, Jie Feng, Ding DuAtropsiomers bearing multiple stereogenic axes are of increasing relevance to materials science, pharmaceuticals, and catalysis. However, catalytic enantioselective construction of […]Yuzhi Ren
- Highly Selective DNA Aptamer Sensor for Intracellular Detection of Coenzyme A Tháng 3 28, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC00332F, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yuan Ma, Whitney Lewis, Xiangli Shao, Peng Yan, Quanbing Mou, Linggen Kong, Weijie Guo, Yi LuDetecting Coenzyme A (CoA) in cells is vital for understanding its role in metabolism. DNA aptamers, though widely […]Yuan Ma
- Consequences of the failure of equipartition for the p–V behavior of liquid water and the hydration free energy components of a small protein Tháng 3 28, 2025Chem. Sci., 2025, Advance ArticleDOI: 10.1039/D4SC08437C, Edge Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Dilipkumar N. Asthagiri, Arjun Valiya Parambathu, Thomas L. BeckIn MD simulations of aqueous systems using a rigid-body description for water molecules, a small time-step is needed to ensure consistent prediction of simulated properties, […]Dilipkumar N. Asthagiri
- A nearly perfect icosahedral Ir@Au12 superatom with superior photoluminescence obtained by ligand engineering Tháng 3 28, 2025Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC00561B, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Katsuya Mutoh, Teppei Yahagi, Shinjiro Takano, Sonomi Kawakita, Takeshi Iwasa, Tetsuya Taketsugu, Tatsuya Tsukuda, Takuya NakashimaHeterometal doping and the introduction of surface ligands drastically alter the optical and photophysical properties of gold-based superatoms […]Katsuya Mutoh
- Computational Discovery and Systematic Analysis of Protein Entangling Motifs in Nature: From Algorithm to Database Tháng 3 30, 2025
