RSC – Lab Chip latest articles- Groove-aided sacrificial molding for fabrication of an in vitro vascular model with branches using ECM-derived materials Tháng 8 5, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00214A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jumpei Muramatsu, Michinao Hashimoto, Shigenori Miura, Hiroaki OnoeThis paper describes a fabrication method for an in vitro branched vascular model using ECM-derived materials. This method helps prevent deformation of water-soluble templates in the sacrificial […]Jumpei Muramatsu
- A compact sample-to-answer system for rapid MRSA detection in serum based on reagent-free electrophoretic purification of nucleic acids and colorimetric LAMP Tháng 8 5, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00152H, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yung Ching Lee, Yang Bu, Sheng Ni, Yuze Liu, Anni Hu, Levent YobasMethicillin-resistant Staphylococcus aureus (MRSA) poses a significant threat as a leading cause of nosocomial infections, inflicting severe complications and fatalities worldwide. Its […]Yung Ching Lee
- Correction: Pipette-operable microfluidic devices with hydrophobic valves in sequential dispensing with various liquid samples: multiplex disease assay by RT-LAMP Tháng 8 4, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC90081F, Correction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Yen-Wei Chang, Jhih-Pu Lin, Shiu-Jie Ling, Yen-Chun Chen, Helene Minyi Liu, Yen-Wen LuTo cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) […]Yen-Wei Chang
- Orbital Shaker-Driven Gut-on-Chip Platform for Drug-Induced Permeability and Microenvironment Studies Tháng 8 4, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00333D, PaperNishanth Venugopal Menon, Jeeyeon Lee, Hung Truong Dong, Sriram Bharathkumar, Chwee Teck LimGut-on-chip platforms replicate realistic gut microenvironments but face limited adoption due to their complex designs, expensive fabrication, and specialized instrumentation that increases operational complexity. In this study, we present a...The content of this RSS Feed (c) The […]Nishanth Venugopal Menon
- Simple additive-based modifications of PDMS for long-term hydrophilic stability Tháng 8 4, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00532A, PaperEunyoung Park, Seungjin Kang, Ung Hyun KoSimple fabrication of hydrophilic PDMS via mixing of PDMS and a PDMS–PEG block copolymer, without plasma or surface modification.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society […]Eunyoung Park
- Microfluidics for geosciences: metrological developments and future challenges Tháng 8 3, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00108K, Critical Review Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Sophie Roman, Flore Rembert, Anthony R. Kovscek, Jenna PoonoosamyThis review addresses the main metrological developments over the past decade for microfluidics applied to geosciences.To cite this article before page numbers are assigned, use […]Sophie Roman
- Programmable 3DP Microfluidic Bio-Reaction System: Automated LAMP-on-a-Chip Tháng 8 3, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00003C, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Mehmet Tugrul Birtek, Nazente Atçeken, Savas TasogluPoint-of-care (PoC) devices have revolutionized healthcare by enabling remote diagnostics and therapeutics, with microfluidic systems playing a pivotal role in their advancement. This study focuses on the detailed […]Mehmet Tugrul Birtek
- Enhancing commercially available immunoassays through a customized electrokinetic biomolecular preconcentration device Tháng 8 3, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00179J, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Barak Sabbagh, Sinwook Park, Gilad YossifonIon concentration polarization (ICP) based molecular preconcentration.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The […]Barak Sabbagh
- Centrifugal microfluidic chip with an air gap for oil-free production of enhanced adipogenic multicellular microspheres Tháng 7 31, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00467E, PaperXueqing Ren, Xin Wang, Xiaolu Cai, Yi Zou, Peng Chen, Bi-Feng Liu, Yiwei LiHydrogel microspheres produced by centrifugal microfluidic chips with integrated air gaps emerge as crucial platforms for three-dimensional cell culture systems and tissue engineering applications.To cite this article before page numbers are assigned, use the DOI form […]Xueqing Ren
- Design and Characterization of a Self-Powered Microneedle Microfluidic System for Interstitial Fluid Sampling Tháng 7 31, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00590F, Communication Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Christopher Sharkey, Angélica F. Aroche, Isabella G. Agusta, Hannah Nissan, Tamoghna Saha, Sneha Mukherjee, Jack Twiddy, Michael D. Dickey, Orlin Velev, Michael DanieleDermal interstitial fluid (ISF) is a promising source of biomarkers for point-of-care […]Christopher Sharkey
- A high-speed sequential liquid compartmentalization method for digital loop-mediated isothermal amplification in a microfluidic device Tháng 7 30, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00486A, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Riku Honda, Taketo Saruwatari, Daigo Natsuhara, Yuka Kiba, Shunya Okamoto, Moeto Nagai, Masashi Kitamura, Takayuki ShibataA pipette-operated microfluidic digital LAMP platform enables the absolute quantification of nucleic acid targets in 10 000 nL-scale reaction microchambers, […]Riku Honda
- Engineering a diagnostic platform based on a spatially resolved electrochemiluminescence immunoassay for low-plex biomarker detection at point-of-care: mild traumatic brain injury and cardiac applications Tháng 7 29, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00360A, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Milica Jović, Denis Prim, Gabriel Paciotti, Marc E. PfeiferNovel point-of-care diagnostic platform for multi-biomaker detection based on spatially-resolved ECL.To cite this article before page numbers are assigned, use the DOI form of citation above.The […]Milica Jović
- A lung tumor-on-a-chip model recapitulates the effect of hypoxia on radiotherapy response and FDG-PET imaging Tháng 7 29, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00373C, PaperRohollah Nasiri, Myra Kurosu Jalil, Veronica Ibanez Gaspar, Andrea Sofia Flores Perez, Hieu Thi Minh Nguyen, Syamantak Khan, Sindy K. Y. Tang, Yunzhi Peter Yang, Guillem PratxA microfluidic tumor-on-a-chip platform reveals hypoxia-induced radioresistance and metabolic shifts via integrated PET imaging.To cite this article before page numbers are assigned, use […]Rohollah Nasiri
- Evaluating Caplacizumab’s Potential to Mitigate Thrombosis Risk in Aortic Valve Stenosis: A Microfluidic and Computational Approach Tháng 7 29, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00361J, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Saeedreza Zeibi Shirejini, Mehrdad Khamooshi, Damien Riska, Martin Nikolov, Marjan Azimi, Shiyen L. Perera, Josie Carberry, Karen Alt, Shaun Gregory, Christoph HagemeyerAortic valve stenosis is a progressive cardiovascular disease associated with increased thrombotic risk […]Saeedreza Zeibi Shirejini
- Liquid transport strategies in wearable and implantable microfluidic systems Tháng 7 29, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00593K, Critical Review Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Qi Wang, Yizhen Jia, Jinghua LiLiquid transport is an essential functionality in microfluidic operation. This review summarizes emerging strategies for liquid management in bioelectronics, with a focus on system-level integration and applications.To cite […]Qi Wang
- Optical-driven Miniature Robots: Driving Mechanism, Applications and Future Trends Tháng 7 28, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00621J, Critical ReviewXiaowen Wang, Sen Jia, Yingnan Gao, Changyou Liu, Yaping Wang, Anqin Liu, Wenguang YangMiniature robots can complete complex tasks at the micro-scale, which have shown great application potential in fields such as biomedicine and environmental monitoring. As a renewable energy source, light is...The content of this RSS Feed […]Xiaowen Wang
- Accelerated maturation of branched organoids confined in collagen droplets Tháng 7 28, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00287G, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Iris Elke Ruider, Anna Pastucha, Marion K. Raich, Wentao Xu, Yan Liu, Maximilian Reichert, David A. Weitz, Andreas R. BauschDroplet-based organoid culture offers several advantages over conventional bulk organoid culture, such as improved yield, […]Iris Elke Ruider
- Inverse 3D ‘lab-on-a-chip’ polymeric microfilms for selective capture of circulating tumor cells from patients' blood Tháng 7 25, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D4LC01105H, PaperRituja Gupta, Saloni Andhari, Semonti Nandi, Tanvi Deshpande, Narendra Kale, Chandrashekhar Bobade, Gourishankar Aland, Sreeja Jayant, Atul Bharde, Aravindan Vasudevan, Pankaj Chaturvedi, Kumar Prabhash, Yuvraj Patil, Jayant Khandare3D polymeric microfilms chemically modified with targeting ligands capture circulating tumor cells from cancer patients' blood samples with high specificity and provide […]Rituja Gupta
- Rocker or pump? Transcriptomic response of endothelial cells exposed to peristaltic pump-based unidirectional flow vs. rocker-induced bidirectional flow Tháng 7 24, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00553A, Communication Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Negar Vahdani, Prateek Arora, Lisette van Os, Denise Ackermann, Nadia Mercader, Olivier T. GuenatHundreds of genes were altered, underscoring how pump- or rocker-induced flow shapes endothelial behavior at the molecular level.To cite this article […]Negar Vahdani
- Microfluidic Investigation of CO2 Foam Flow in a Heterogeneous Porous Medium Tháng 7 24, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00544B, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Nikoo Moradpour, Peichun Amy TsaiCO2 foam has emerged as a promising alternative to CO2 gas for mobility control in enhanced oil recovery (EOR) applications, yet the pore-scale dynamics and mechanisms governing foam flow and...The […]Nikoo Moradpour
- Groove-aided sacrificial molding for fabrication of an in vitro vascular model with branches using ECM-derived materials Tháng 8 5, 2025
