RSC – Lab Chip latest articles
- Microengineered Diabetic Wound-on-a-Chip Model for Emulating Chronic Wound Dynamics Tháng 10 16, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00500K, PaperShivam Sharma, Anil KishenDiabetic wounds, which affect 19–34% of individuals with Diabetes Mellitus, remain a serious complication due to their chronic, non-healing nature and high risk of limb amputation. Traditional 2D in vitro...The content of this RSS Feed (c) The Royal Society of ChemistryShivam Sharma
- A multi-valve centrifugal microfluidic for Mycoplasma pneumoniae detection Tháng 10 15, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00667H, PaperGuangyao Chen, Yu Lu, Hao Shen, Jing Zhang, Yizhu Liu, Liwei Xue, Liguo ChenIntegrated detection process based on centrifugal microfluidic chips.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of ChemistryGuangyao Chen
- Active droplet generation in flow-focusing microfluidics under influence of transverse magnetic field Tháng 10 15, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00805K, PaperBoris Kichatov, Vladimir Sudakov, Dariya Kalyuzhnaya , Alexey Korshunov, Petr RyapolovMagnetic fields can be used to control the process of magnetic fluid dispersion in microfluidics. Here we demonstrate a method for generating magnetic fluid droplets of a given size and...The content of this RSS Feed (c) The Royal Society […]Boris Kichatov
- A luminescence-based point-of-care HIV viral load test for antiretroviral therapy monitoring Tháng 10 15, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00636H, PaperSungwan Kim, Hak-Rae Hong, Jong-Min Oh, Juhyeon Chun, Adharsh Chellappaa, Jungmin Yoo, Syed M Husain, Jaebaek Lee, Jisan Kim, Prudhvi Thirumalaraju, Younseong Song, Manoj Kumar Kanakasabapathy, Juyong Gwak, Joseph Michael Hardie, Daniel R Kuritzkes, Jonathan Z Li, Athe M Tsibris, Hadi ShafieeEffective monitoring of HIV treatment remains constrained by […]Sungwan Kim
- OpenLM: An Open-Source Pixel Super-Resolution Platform for Lens-Free Microscopy with Applications in Bacterial Growth Monitoring and Deep Learning-based Bacterial Detection Tháng 10 14, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00719D, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Weiming Xu, Samiha Ahmed, Majed Althumayri, Azra Yaprak Tarman, Mert Kerem Ulku, Karston Yong, Muhammed Veli, Hatice Ceylan KoydemirMonitoring bacterial growth and detecting early-stage colony formation are essential tasks in biomedical research, clinical diagnostics, […]Weiming Xu
- Embroidered paper-based electrochemical wearable device for pH monitoring in wounds Tháng 10 14, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00609K, PaperLaura Belcastro, Luca Fiore, HIMA ZAFAR, Mitar Simic, Raffaele Vitiello, Marco Libertini, Florigio Lista, Giulio Maccauro, Goran M Stojanović, Fabiana ArduiniHerein, we reported the first microfluidic thread/paper-based analytical electrochemical device (μTPAD) by harnessing the synergic combination of embroidery as a manufacturing technique and paper-based technology. The effectiveness of the […]Laura Belcastro
- Design, fabrication, and characterization of a microbubble array microphysiological system Tháng 10 13, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00411J, PaperLukas B. Jenkins, Hasibul Hasan Hredoy, Hossein Abolhassani, Chiao Yun Chen, Michelle Duan, Lisa A. DeLouiseMicrobubble (MB) technology is uniquely suited for integration into microphysiological systems (MPS) for high throughput three-dimensional (3D) tissue culture, drug screening and toxicity testing.To cite this article before page numbers are assigned, use the […]Lukas B. Jenkins
- Natural Rock-Derived Microfluidic Chip for Probing Multicomponent Mineral Dissolution Dynamics Tháng 10 13, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00718F, PaperYingxue Hu, Haozhou Wang, Wei Xu, Haifeng Liu, Lei He, Zhaolin Gu, Junwei SuMineral dissolution plays a fundamental role in key subsurface processes, involving complex couplings among fluid flow, mass transport, and geochemical reactions. In this study, we present microfluidic chips fabricated from...The content of this RSS Feed (c) […]Yingxue Hu
- Gravity-perfused airway-on-a-chip optimized for quantitative BSL-3 studies of SARS-CoV-2 infection: barrier permeability, cytokine production, immunohistochemistry, and viral load assays Tháng 10 13, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00510H, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Shannon L. Faley, Niloufar A. Boghdeh, David K. Schaffer, Eric C. Spivey, Farhang Alem, Aarthi Narayanan, John P. Wikswo, Jacquelyn A. BrownGravity-perfused, air–liquid interface airway chip optimized for BSL-3 infectious disease studies with rapid […]Shannon L. Faley
- Integrated microfluidic three-organ chip for real-time toxicity analysis of fluorotelomer alcohols in the gut–vascular–nerve axis Tháng 10 12, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00631G, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Xiaodan Ding, Ning Xu, Wei Zhang, Peilong WangA gut–vascular–nerve axis chip recapitulates bidirectional gut–brain communication through an endothelial interface, coupled with on-chip solid-phase extraction-mass spectrometry for real-time PFAS tracking in environmental toxicology research.To cite […]Xiaodan Ding
- A microfluidic rheometer for tumor mechanics and invasion studies Tháng 10 12, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00504C, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Young Joon Suh, Manli Liu, Bangguo Zhu, Mrinal Pandey, Brian C. H. Cheung, Jaemin Kim, Nikolaos Bouklas, Chris Roh, Jeffrey E. Segall, Chung-Yuen Hui, Mingming WuA microfluidic rheometer that enables simultaneous measurements of tumor […]Young Joon Suh
- Resonating with replicability: factors shaping assay yield and variability in microfluidics-integrated silicon photonic biosensors Tháng 10 12, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00575B, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Lauren S. Puumala, Samantha M. Grist, Karyn Newton, So Jung Kim, Stephen Kioussis, Sajida Chowdhury, Maggie Wang, Myra Wei, Yas Oloumi Yazdi, Avineet Randhawa, Yuting Hou, Lukas Chrostowski, Sudip Shekhar, Karen C. CheungA detailed […]Lauren S. Puumala
- Retraction: Gravity-perfused airway-on-a-chip optimized for quantitative BSL-3 studies of SARS-CoV-2 infection: barrier permeability, cytokine production, immunohistochemistry, and viral load assays Tháng 10 12, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D4LC90106A, Retraction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Shannon L. Faley, Niloufar A. Boghdeh, David K. Schaffer, Eric C. Spivey, Farhang Alem, Aarthi Narayanan, John P. Wikswo, Jacquelyn A. BrownTo cite this article before page numbers are assigned, use the DOI form […]Shannon L. Faley
- Endothelial-smooth muscle microgauges for modeling pulmonary arterial vasoregulation Tháng 10 12, 2025Lab Chip, 2025, Accepted ManuscriptDOI: 10.1039/D5LC00474H, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Aanya Sawhney, Raymond Piatt, Miitesh Rathod, Ryan Stack, Chloe Whitworth, William PolacheckPulmonary arterial hypertension (PAH) is a devastating disease for which there is no cure. The pathogenesis of PAH involves endothelial dysfunction and dysregulation […]Aanya Sawhney
- High-throughput nanoparticle manipulation via controlled electro-elasticity and Joule heating in microchannels Tháng 10 9, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00772K, PaperXinlei Qi, Shuhao Ma, Guoqing HuHigh-throughput nanoparticle manipulation is achieved in microchannels via controlled electro-elasticity, while Joule heating is mitigated through a straightforward cooling strategy to enable operation under high electric fields.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of […]Xinlei Qi
- Synchronized droplet nozzle for in-vacuum X-ray scattering experiments Tháng 10 9, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00063G, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Adil Ansari, Roberto C. Alvarez, Konstantinos Karpos, Dimitra Manatou, Garett Nelson, Reza Nazari, Tanner Hochberg, John Tamayo, Hannah Nockideneh, Creed Hudson, Anubhav Singhal, Divyanshu Tandon, Natasha Forrand, Hao Hu, Diandra Doppler, Mukul Sonker, Alexandra […]Adil Ansari
- High-resolution time-lapse imaging of droplet-cell dynamics via optimal transport and contrastive learning Tháng 10 9, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00351B, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Luca Johannes Schlotheuber, Michael Vollenweider, Sven Gutjahr, Tiago Hungerland, Richard Danis, Weronika Ormaniec, Aline Linder, Valentina Boeva, lnes Lüchtefeld, Klaus EyerThis study describes a label-free pipeline combining visual detection, contrastive learning, and optimal transport […]Luca Johannes Schlotheuber
- In situ formation and culture of cell spheroids in a low-binding 3D-printed biochip Tháng 10 7, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00503E, PaperAlexandre Martins, Sylvie Klieber, Charlotte Le Graët, Eric Leclerc, Cécile Legallais, Rachid JellaliWe developed a standardized 3D-printed low-binding biochip allowing both in situ formation and maintenance of hepatic spheroids. The spheroids displayed outstanding viability and metabolic competencies after 11 days of culture.To cite this article before page numbers are […]Alexandre Martins
- Development of a contraction-free, vascularized full-thickness skin-on-a-chip platform for modeling immune responses and inflammation in atopic dermatitis Tháng 10 5, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00606F, PaperKyunghee Kim, Hyeji Jang, Eunyul Kim, Hyeju Kim, Gun Yong SungA vascularized skin-on-a-chip model recapitulating immune–vascular interactions for physiologically relevant human skin research.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of ChemistryKyunghee Kim
- Spatiotemporal temperature control by holographic heating microscopy unveils cellular thermosensitive calcium signalling Tháng 10 5, 2025Lab Chip, 2025, Advance ArticleDOI: 10.1039/D5LC00675A, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Kotaro Oyama, Ayumi Ishii, Shuhei Matsumura, Tomoko G. Oyama, Mitsumasa Taguchi, Madoka SuzukiHolographic heating microscopy extended the ability of spatiotemporal temperature control for investigating thermosensitive Ca2+ signalling and thermally manipulating cellular functions.To cite this […]Kotaro Oyama
- Microengineered Diabetic Wound-on-a-Chip Model for Emulating Chronic Wound Dynamics Tháng 10 16, 2025