RSC – Lab Chip latest articles- Development of a nasal airway-on-chip co-culture model to study particulate matter exposure Tháng 3 6, 2026Lab Chip, 2026, Accepted ManuscriptDOI: 10.1039/D5LC00978B, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Amanda Walls, Adrienne Vaughan, Kartik BalachandranParticulate matter (PM) is a major component of urban air pollution and is strongly associated with respiratory diseases. However, the mechanisms of PM-induced inflammation remain poorly understood due to […]Amanda Walls
- Oscillatory flow for contactless particle trapping Tháng 3 5, 2026Lab Chip, 2026, Advance ArticleDOI: 10.1039/D5LC00813A, PaperGabrielle Saint-Girons, Kaustav A. Gopinathan, Sajad Razavi Bazaz, Li Zhan, Jon F. Edd, Mehmet TonerOscillatory flow in channels with asymmetry in the flow direction drives particles towards stable 3D attraction regions, enabling contact free trapping.To cite this article before page numbers are assigned, use the DOI form of citation […]Gabrielle Saint-Girons
- Macroporous transport – mesoporous catalysis: a rapid microfluidic-fabricated biomimetic sponge photocatalytic microsphere reactor Tháng 3 4, 2026Lab Chip, 2026, Advance ArticleDOI: 10.1039/D6LC00078A, PaperQikai Wang, Wenwen Shi, Qihang Yang, Feng Teng, Qiuhong CuiA biomimetic sponge-structured photocatalytic microsphere reactor was batch-fabricated by combining microfluidic technology with confined self-assembly.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of […]Qikai Wang
- Dissociable perfusion chip (DPC): perfusable microfluidic chip for single-cell screening of anti-cancer drugs in live glioblastoma explants Tháng 3 4, 2026Lab Chip, 2026, Advance ArticleDOI: 10.1039/D5LC01105A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Darragh G. Kennedy, Wenting Zhao, Terry L. Chern, Michael Yang, Nicolas Acosta, Siddarth Arumugam, Pavan Upadhyayula, Julia Furnari, Athanassios Dovas, Jeffrey N. Bruce, Peter Canoll, Samuel K. Sia, Peter A. SimsNew approaches are needed […]Darragh G. Kennedy
- High-throughput single-cell proteomics and transcriptomics from same cells with a nanoliter-scale, spin-transfer approach Tháng 3 3, 2026Lab Chip, 2026, Advance ArticleDOI: 10.1039/D5LC01008J, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Pranav Dawar, Lye Meng Markillie, Sarah M. Williams, Hugh D. Mitchell, Johannes W. Bagnoli, Joshua Cantlon-Bruce, Anjali Seth, Carter C. Bracken, Ljiljana Paša-Tolić, Ying Zhu, James M. FulcherThis work demonstrates a single-cell multiomic technique […]Pranav Dawar
- Inkube: an all-in-one solution for neuron culturing, electrophysiology, and fluidic exchange Tháng 3 2, 2026Lab Chip, 2026, Advance ArticleDOI: 10.1039/D5LC00971E, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Benedikt Maurer, Selina Fassbind, Tobias Ruff, Jens Duru, Giusy Spacone, Theo Rodde, János Vörös, Stephan J. IhleA compact open-source platform merging cell culturing, electrophysiology, and automated perfusion, which provides robust environmental control and continuous […]Benedikt Maurer
- High-Throughput and Efficient Fabrication of Engineered Skeletal Muscle Tissue via Streamlined 3D Multimaterial Bioprinting Tháng 3 2, 2026Lab Chip, 2026, Accepted ManuscriptDOI: 10.1039/D5LC01040C, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Tae-Eun Lim, Ashfaq Ahmad, Yeong-Jin Choi, Hee Gyeong YiSkeletal muscle diseases have led to an increasing need for a range of physiologically relevant organ-on-a-chip and three-dimensional (3D) culture platforms owing to their clinical significance […]Tae-Eun Lim
- Real-time impedance-based cell migration measurements with integrated electrodes on porous membranes for next generation microphysiological systems Tháng 3 2, 2026Lab Chip, 2026, Advance ArticleDOI: 10.1039/D5LC00898K, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Karina Torres-Castro, Aditya Rane, Darwin R. ReyesIntegrated sensors on both sides of a track-etched polyester membrane in this next generation microphysiological system enable real-time monitoring of cancer cell migration by simultaneously tracking impedance on […]Karina Torres-Castro
- Hydrogel microwell with pneumatic soft actuator for compression formation of three-dimensional cellular tissue Tháng 2 27, 2026Lab Chip, 2026, Advance ArticleDOI: 10.1039/D5LC00731C, PaperRyota Kawamae, Atsushi Takata, Kenjiro Takemura, Yuta KurashinaA unique culture system was devised by integrating a pneumatic soft actuator and a hydrogel microwell for cellular tissue formation.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The […]Ryota Kawamae
- 3D ECM-Inflammation Model on a Microfluidic Chip for Neutrophil Transmigration from Whole Blood Investigations Tháng 2 27, 2026Lab Chip, 2026, Accepted ManuscriptDOI: 10.1039/D5LC00554J, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Shide Bakhtiari, Vanessa Velasco, Ronald DavisNeutrophils have been linked to several inflammation diseases. To study the role of neutrophils in inflammation diseases and conditions, in vitro inflammation assays have been developed. Two drawbacks of […]Shide Bakhtiari
- Vascularizing organoids-on-chip for perfused and personalized models Tháng 2 27, 2026Lab Chip, 2026, Advance ArticleDOI: 10.1039/D5LC00890E, Critical Review Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Bianca Menzani, Priscille De Gea, Xavier Gidrol, Emily TubbsThis review discusses the current strategies and technical considerations for vascularizing organoids-on-chip, highlighting their potential to improve physiological relevance, functional performance, personalization and translational applicability.To […]Bianca Menzani
- Dual Vision-equipped Microfluidic Chip for Spatiotemporal Sequential Pick-and-Place of Oocytes Tháng 2 27, 2026Lab Chip, 2026, Accepted ManuscriptDOI: 10.1039/D5LC01118C, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Shuzhang LIANG, Hao Mo, Yuguo Dai, Hirotaka Sugiura, Satoshi Amaya, Fumihito AraiOocytes have long been used as a fundamental biological model in bioengineering research such as gene expression analysis, electrophysiological measurements, and drug screening. […]Shuzhang LIANG
- Integrated strategy for breast cancer biomarker analysis using dual ionic liquid aqueous biphasic systems and microfluidic immunoassays Tháng 2 26, 2026Lab Chip, 2026, Advance ArticleDOI: 10.1039/D5LC01010A, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Maria S. M. Mendes, Inês Agostinho, Maria C. Souza, Virginia Chu, Mara G. Freire, Francisca A. e Silva, João P. CondeMicrofluidic HER2 detection is enhanced by a dual ionic liquid aqueous biphasic system that […]Maria S. M. Mendes
- Integrated microfluidic platform based on potentiometric Sonogel-Carbon sensors for the simultaneous determination of Na+ and K+ in untreated human plasma and serum Tháng 2 25, 2026Lab Chip, 2026, Advance ArticleDOI: 10.1039/D6LC00117C, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Álvaro Jesús Sainz-Calvo, Álvaro Cordero-Hernández, Marina Jiménez-Rodríguez, Virginia García-Rodríguez, Juan José García-Guzmán, Dolores Bellido-Milla, José María Palacios-Santander, Laura Cubillana-AguileraIn the present work, two potentiometric sensors for the simultaneous determination of sodium and potassium ions […]Álvaro Jesús Sainz-Calvo
- On-chip acoustic chaotic micromixer for point-of-care applications Tháng 2 24, 2026Lab Chip, 2026, Advance ArticleDOI: 10.1039/D5LC01183C, PaperXian Chen, Chuanchao Zhang, Yaping Wang, Xuexin Duan, Yunhua GaoWe proposed an acoustofluidic platform actuated by the Lamb wave resonator array, which facilitates sample pretreatment, chaotic mixing, analyte trapping and detection on a single chip for the truly “sample-in-answer-out” point-of-care detection.To cite this article before page numbers are assigned, […]Xian Chen
- Stroke Volume Analog on a Chip - In Vitro Hydrodynamic Model of Cardiac Pumping Efficiency Tháng 2 23, 2026Lab Chip, 2026, Accepted ManuscriptDOI: 10.1039/D5LC00547G, PaperJohn Zimmerman, Luke A. MacQueen, Douglas Henze, Daniel J. Drennan, Sean L. Kim, Herdeline Ann Ardoña, Suji Choi, Qianru Jin, Kevin Kit ParkerStroke volume serves as a key metric of heart performance. Despite its central importance in diagnosing many cardiomyopathies, there exists limited in vitro models whose readouts can […]John Zimmerman
- A portable, low-cost, point-of-care DNA amplification kit with impedance-based detection for decentralized antimicrobial resistance diagnostics Tháng 2 20, 2026Lab Chip, 2026, Advance ArticleDOI: 10.1039/D6LC00062B, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Koosha Karimi, Miriam Arroyo, Erin E. Chille, Timothy G. Stephens, Donal Barrett, Vicent Pelechano, Debashish Bhattacharya, Mehdi JavanmardThis study presents a low-cost, portable DNA amplification kit that performs modified LAMP to produce DNA nanoballs, […]Koosha Karimi
- Correction: Reversible and reusable compartmentalized thermoplastic chip for coculture of dorsal root ganglion neurons Tháng 2 20, 2026Lab Chip, 2026, Advance ArticleDOI: 10.1039/D5LC90129D, Correction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Solène Moreau, Raul Flores-Berdines, Anne Simon, Tatiana El Jalkh, Guillaume Taret, Anna Fomina, Céline Dargenet-Becker, André Estevez-Torres, Sophie Bernard, Hugo SalmonTo cite this article before page numbers are assigned, use the DOI form of […]Solène Moreau
- Vector-free DNA transfection by nuclear envelope mechanoporation Tháng 2 20, 2026Lab Chip, 2026, Advance ArticleDOI: 10.1039/D5LC00871A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Leyla Akh, Apresio K. Fajrial, Sunwoo Sohn, Benjamin Seelbinder, Xin Xu, Wei Tan, Jill E. Slansky, Corey P. Neu, Xiaoyun DingA nanolancet-based microfluidic mechanoporation device can produces reliable pores on the cell membrane and […]Leyla Akh
- Engineering organs-on-a-chip via multi-channel microfluidics Tháng 2 19, 2026Lab Chip, 2026, 26,1739-1785DOI: 10.1039/D5LC00598A, Critical ReviewJi Qiu, Jia Yang, Lihao Liu, Jiameng Wen, Jiachen Yang, Wenwan Shi, Xiaoxiang Gao, Jing Sun, Ling Bai, Xiaojiang Liu, Zhongze GuThis review summarizes the design strategies, fabrication methods and applications of multi-channel microfluidic organ-on-a-chip systems, and outlines the key challenges and future opportunities for advancing disease modeling and […]Ji Qiu
- Development of a nasal airway-on-chip co-culture model to study particulate matter exposure Tháng 3 6, 2026
