RSC – Nat. Prod. Rep. latest articles- Synthetic biology for heterologous expression and engineering of fungal polyketide synthases Tháng 3 2, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D5NP00020C, HighlightSidharth Jayachandran, Adrian Enrique Gadar-Lopez, Ling Chen, Kasper Krunderup Jakobsen, Coco Xie, Therese Horch, Jay D. Keasling, Pablo Cruz-MoralesPolyketide synthases (PKSs) are essential enzymatic systems that produce a wide range of natural products.To cite this article before page numbers are assigned, use the DOI form of citation above.The […]Sidharth Jayachandran
- Microbial production of C7–C9 aromatic building blocks for the production of natural products Tháng 2 23, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D5NP00068H, Review ArticleQiaoqiao Dai, Jiaqi Xu, Jing Wu, Xiaomin Li, Cong Gao, Guipeng Hu, Liming LiuThis review surveys representative C7–C9 aromatic compounds, outlining their microbial biosynthetic pathways, key metabolic challenges, and recent advances in metabolic engineering for their microbial production.To cite this article before page numbers are assigned, use […]Qiaoqiao Dai
- Editorial: Microbial host and metabolic engineering for natural product discovery and production Tháng 2 16, 2026Nat. Prod. Rep., 2026, 43,279-280DOI: 10.1039/D6NP90006B, EditorialAlessandra S. Eustaquio, Eriko Takano, Tobias A. M. GulderAlessandra Eustaquio, Eriko Takano and Tobias Gulder introduce the Natural Product Reports themed issue on microbial host and metabolic engineering for natural product discovery and production.The content of this RSS Feed (c) The Royal Society of ChemistryAlessandra S. Eustaquio
- Correction: Progress in the discovery and development of anticancer agents from marine cyanobacteria Tháng 2 9, 2026Nat. Prod. Rep., 2026, 43,391-392DOI: 10.1039/D6NP90002J, Correction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Hendrik Luesch, Emma K. Ellis, Qi-Yin Chen, Ranjala RatnayakeThe content of this RSS Feed (c) The Royal Society of ChemistryHendrik Luesch
- Hot off the Press Tháng 2 9, 2026Nat. Prod. Rep., 2026, 43,281-285DOI: 10.1039/D6NP90001A, Hot off the Press ArticleRobert A. Hill, Andrew SutherlandA personal selection of 32 recent papers is presented covering various aspects of current developments in bioorganic chemistry and novel natural products such as candindole A from Aspergillus candidus.The content of this RSS Feed (c) The Royal Society of ChemistryRobert A. Hill
- Microbial natural products activated by plant stress Tháng 2 2, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D5NP00062A, Highlight Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Barbara I. AdaikpohHighlighting studies that link plant stress to the activation of antimicrobial biosynthetic gene clusters in beneficial microbes, thereby illustrating chemical interactions in the plant's microenvironment that can inform natural product discovery.To […]Barbara I. Adaikpoh
- Isolation and synthesis of bisabosquals, fungal triprenyl phenol meroterpenoids with a densely functionalised bisabolane core Tháng 2 2, 2026Nat. Prod. Rep., 2026, Advance ArticleDOI: 10.1039/D5NP00085H, HighlightJames P. Shephard, David W. LuptonBisabosquals and seco-bisabosquals are unusual fungal meroterpenoids with a densely functionalised bisabolane core. Herein, we highlight their isolation, biosynthesis and bioactivities along with studies on their total syntheses.To cite this article before page numbers are assigned, use the DOI form of citation above.The […]James P. Shephard
- Engineering microbiomes for natural product discovery and production Tháng 9 23, 2025Nat. Prod. Rep., 2026, 43,301-312DOI: 10.1039/D5NP00038F, Highlight Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Francesco Del Carratore, Rainer BreitlingThe exciting advancements in multi-omics, genetic engineering and computational tools are paving the way for the engineering of synthetic communities for the discovery and production of natural products. Created in […]Francesco Del Carratore
- Streptomyces as a versatile host platform for heterologous production of microbial natural products Tháng 9 8, 2025Nat. Prod. Rep., 2026, 43,371-390DOI: 10.1039/D5NP00036J, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Constanze Lasch, Maksym Myronovskyi, Andriy LuzhetskyyThis review outlines recent strategies for genome mining, synthetic refactoring, and host-based expression of natural product biosynthetic gene clusters, focusing on discovery, dereplication, and scalable production.The content of […]Constanze Lasch
- The development of Burkholderia bacteria as heterologous hosts Tháng 7 27, 2025Nat. Prod. Rep., 2026, 43,335-351DOI: 10.1039/D5NP00024F, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Stephanie C. Heard, Alessandra S. EustáquioWe review Burkholderia bacterial strains that have been tested as heterologous hosts and the natural products obtained. We also compare host characteristics and their stage of development.The content […]Stephanie C. Heard
- Toward a unified pipeline for natural product discovery: tools and strategies for NRPS and PKS pathway exploration and engineering Tháng 7 27, 2025Nat. Prod. Rep., 2026, 43,352-370DOI: 10.1039/D5NP00041F, Review ArticleBiyan Chen, Emre F. Bülbül, SeoungGun Bang, Hannah A. Minas, Kenan A. J. BozhüyükThis review outlines integrated platforms combining genome mining, computational design, synthetic biology, and high-throughput screening to enable the programmable biosynthesis of tailor-made natural products.The content of this RSS Feed (c) The Royal Society of ChemistryBiyan Chen
- Green genes from blue greens: challenges and solutions to unlocking the potential of cyanobacteria in drug discovery Tháng 7 14, 2025Nat. Prod. Rep., 2026, 43,286-300DOI: 10.1039/D5NP00016E, Viewpoint Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Benjamin Philmus, Nicole E. Avalon, Yousong Ding, Drew T. Doering, Alessandra S. Eustáquio, William H. Gerwick, Hendrik Luesch, Jimmy Orjala, Shaz Sutherland, Arnaud Taton, Daniel UdwaryCyanobacteria are prolific producers of bioactive natural products. In […]Benjamin Philmus
- Accelerating enzyme discovery and engineering with high-throughput screening Tháng 10 14, 2024Nat. Prod. Rep., 2026, 43,313-334DOI: 10.1039/D4NP00031E, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Eray U. Bozkurt, Emil C. Ørsted, Daniel C. Volke, Pablo I. NikelRecent progress in the DBTL cycle, including machine learning, facilitated enzyme mining for biocatalysis. Automation and standardization of library construction, coupled to […]Eray U. Bozkurt
- Synthetic biology for heterologous expression and engineering of fungal polyketide synthases Tháng 3 2, 2026
