RSC – Nat. Prod. Rep. latest articles
- Modular polyketide synthase-derived insecticidal agents: from biosynthesis and metabolic engineering to combinatorial biosynthesis for their production Tháng Một 24, 2023Nat. Prod. Rep., 2023, Advance ArticleDOI: 10.1039/D2NP00078D, HighlightJeong Sang Yi, Jung Min Kim, Yeon Hee Ban, Yeo Joon YoonThis highlight covers the recent advances in the metabolic engineering and combinatorial biosynthesis of insecticidal agents produced by modular type I PKSs from actinomycete.To cite this article before page numbers are assigned, use the DOI form of […]Jeong Sang Yi
- The volatile chemistry of orchid pollination Tháng Một 24, 2023Nat. Prod. Rep., 2023, Advance ArticleDOI: 10.1039/D2NP00060A, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.James Perkins, Tobias Hayashi, Rod Peakall, Gavin R. Flematti, Björn BohmanOrchids are amongst the most diverse of all plant families, and produce a wide array of volatile compounds for pollinator attraction.To cite […]James Perkins
- Revisiting the manzamine biosynthetic hypothesis Tháng Một 17, 2023Nat. Prod. Rep., 2023, Advance ArticleDOI: 10.1039/D2NP00082B, HighlightAlexander T. Piwko, Brian G. Miller, Joel M. SmithA re-evaluation of the biosynthetic hypothesis of the manzamine natural products is discussed. In addition to considering its unified origins with other marine alkaloids, several other plausible biosynthetic hypotheses are critically evaluated.To cite this article before page numbers are assigned, […]Alexander T. Piwko
- Natural sesquiterpene quinone/quinols: chemistry, biological activity, and synthesis Tháng Một 13, 2023Nat. Prod. Rep., 2023, Advance ArticleDOI: 10.1039/D2NP00045H, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Xin-Hui Tian, Li-Li Hong, Wei-Hua Jiao, Hou-Wen LinThis review summarizes 196 reports related to 558 new sesquiterpene quinone/quinols spanning the years 2010–2021.To cite this article before page numbers are assigned, use the […]Xin-Hui Tian
- Extraction techniques for bioactive compounds of cannabis Tháng Một 10, 2023Nat. Prod. Rep., 2023, Advance ArticleDOI: 10.1039/D2NP00059H, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Aitor Sainz Martinez, Olga Lanaridi, Kristof Stagel, Heidi Halbwirth, Michael Schnürch, Katharina Bica-SchröderThe beneficial properties of bioactive compounds of cannabis has renewed the scientific interest in their recovery. This review presents the […]Aitor Sainz Martinez
- Introduction to engineering the biosynthesis of fungal natural products Tháng Một 9, 2023Nat. Prod. Rep., 2023, 40,7-8DOI: 10.1039/D2NP90047E, EditorialRussell J. Cox, Tobias A. M. GulderGuest editors Russell Cox and Tobias Gulder introduce this Natural Products Reports themed issue summarizing recent progress in engineering the biosynthesis of fungal natural products.The content of this RSS Feed (c) The Royal Society of ChemistryRussell J. Cox
- Optical sensor arrays for the detection and discrimination of natural products Tháng Một 4, 2023Nat. Prod. Rep., 2023, Advance ArticleDOI: 10.1039/D2NP00065B, Review ArticleMaohua Yang, Mei Zhang, Mingyan JiaThis review provides a brief introduction to the optical sensor array and focuses on its progress toward the detection and discrimination of natural products.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this […]Maohua Yang
- Natural nematicidal metabolites and advances in their biocontrol capacity on plant parasitic nematodes Tháng Một 4, 2023Nat. Prod. Rep., 2023, Advance ArticleDOI: 10.1039/D2NP00074A, Review ArticleGuo-Hong Li, Ke-Qin ZhangNatural nematicidal metabolites are important sources of plant parasitic nematodes control.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of ChemistryGuo-Hong Li
- Biosynthesis of indole diterpenes: a reconstitution approach in a heterologous host Tháng Mười Một 2, 2022Nat. Prod. Rep., 2023, 40,202-213DOI: 10.1039/D2NP00031H, Review ArticleTaro Ozaki, Atsushi Minami, Hideaki OikawaReconstitution studies applying the 3-stage strategy to the synthesis of highly elaborated indole diterpenes are reviewed.The content of this RSS Feed (c) The Royal Society of ChemistryTaro Ozaki
- The ‘emodin family’ of fungal natural products–amalgamating a century of research with recent genomics-based advances Tháng Mười 11, 2022Nat. Prod. Rep., 2023, 40,174-201DOI: 10.1039/D2NP00040G, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Kate M. J. de Mattos-Shipley, Thomas J. SimpsonA large and diverse family of fungal compounds are those related to the anthraquinone emodin. By viewing this family as a whole and combining our genetic […]Kate M. J. de Mattos-Shipley
- The expanding CRISPR toolbox for natural product discovery and engineering in filamentous fungi Tháng Mười 6, 2022Nat. Prod. Rep., 2023, 40,158-173DOI: 10.1039/D2NP00055E, Review ArticleClara Woodcraft, Yit-Heng Chooi, Indra RouxThis review provides an overview of CRISPR/Cas-based strategies for biosynthetic gene cluster engineering in filamentous fungi.The content of this RSS Feed (c) The Royal Society of ChemistryClara Woodcraft
- Maleidride biosynthesis – construction of dimeric anhydrides – more than just heads or tails Tháng Chín 20, 2022Nat. Prod. Rep., 2023, 40,128-157DOI: 10.1039/D2NP00041E, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Katherine Williams, Agnieszka J. Szwalbe, Kate M. J. de Mattos-Shipley, Andy M. Bailey, Russell J. Cox, Christine L. WillisWe review studies from early isolation and elucidation to recent bioinformatics and in vitro work […]Katherine Williams
- Deciphering chemical logic of fungal natural product biosynthesis through heterologous expression and genome mining Tháng Chín 19, 2022Nat. Prod. Rep., 2023, 40,89-127DOI: 10.1039/D2NP00050D, Review ArticleChen-Yu Chiang, Masao Ohashi, Yi TangHeterologous expression of biosynthetic gene clusters (BGCs) has become a widely used tool for genome mining of cryptic pathways, bottom-up investigation of biosynthetic enzymes, and engineered biosynthesis of new natural product variants.The content of this RSS Feed (c) The Royal Society of ChemistryChen-Yu Chiang
- Engineering the biosynthesis of fungal nonribosomal peptides Tháng Bảy 6, 2022Nat. Prod. Rep., 2023, 40,62-88DOI: 10.1039/D2NP00036A, Review ArticleLiwen Zhang, Chen Wang, Kang Chen, Weimao Zhong, Yuquan Xu, István MolnárFungal nonribosomal peptides (NRPs) and the related polyketide–nonribosomal peptide hybrid products (PK–NRPs) are a prolific source of bioactive compounds, some of which have been developed into essential drugs.The content of this RSS Feed (c) The Royal Society […]Liwen Zhang
- Structure-based engineering of α-ketoglutarate dependent oxygenases in fungal meroterpenoid biosynthesis Tháng Năm 31, 2022Nat. Prod. Rep., 2023, 40,46-61DOI: 10.1039/D2NP00014H, Review ArticleTakayoshi Awakawa, Takahiro Mori, Richiro Ushimaru, Ikuro AbeThe α-ketoglutarate dependent oxygenases catalyze remarkable chemistries in polyketide-derived fungal meroterpenoid biosynthesis. This review summarizes recent progress in the structure-based engineering of these enzymes.The content of this RSS Feed (c) The Royal Society of ChemistryTakayoshi Awakawa
- Engineering fungal terpene biosynthesis Tháng Năm 22, 2022Nat. Prod. Rep., 2023, 40,28-45DOI: 10.1039/D2NP00020B, Review ArticleZhiyong Yin, Jeroen S. DickschatThis review summarises recent research on metobolic engineering approaches towards terpenes, including work to investigate unknown pathways and to improve accessibility of known compounds.The content of this RSS Feed (c) The Royal Society of ChemistryZhiyong Yin
- Curiouser and curiouser: progress in understanding the programming of iterative highly-reducing polyketide synthases Tháng Năm 10, 2022Nat. Prod. Rep., 2023, 40,9-27DOI: 10.1039/D2NP00007E, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Russell J. CoxCurrent understanding of iterative highly programmed Type 1 PKS that control starter unit selection, chain length, methylation pattern, and stereochemistry.The content of this RSS Feed (c) The Royal Society of ChemistryRussell J. Cox
- Modular polyketide synthase-derived insecticidal agents: from biosynthesis and metabolic engineering to combinatorial biosynthesis for their production Tháng Một 24, 2023