RSC – Nat. Prod. Rep. latest articles
- Bacillus subtilis as a host for natural product discovery and engineering of biosynthetic gene clusters Tháng Ba 11, 2024Nat. Prod. Rep., 2024, Advance ArticleDOI: 10.1039/D3NP00065F, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Hanne Put, Hans Gerstmans, Hanne Vande Capelle, Maarten Fauvart, Jan Michiels, Joleen MasscheleinThis review explores the use of Bacillus as a heterologous host for natural product discovery and engineering, highlighting its unique […]Hanne Put
- Gold-catalyzed cyclization and cycloaddition in natural product synthesis Tháng Ba 8, 2024Nat. Prod. Rep., 2024, Advance ArticleDOI: 10.1039/D3NP00056G, Review ArticleBoxu Lin, Tianran Liu, Tuoping LuoThis review highlights a curated selection of publications utilizing homogeneous gold-catalyzed cycloaddition and cyclization reactions for the total synthesis of natural products reported from 2016 to mid-2023.To cite this article before page numbers are assigned, use the DOI form of citation above.The […]Boxu Lin
- Recent advances in the total synthesis of galantamine, a natural medicine for Alzheimer's disease Tháng Ba 7, 2024Nat. Prod. Rep., 2024, Advance ArticleDOI: 10.1039/D4NP00001C, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Bichu Cheng, Qi Wang, Yi An, Fener ChenThis review discusses the recent synthetic strategies for the total synthesis of galantamine, a natural medicine for the treatment of Alzheimer's disease, focusing on the […]Bichu Cheng
- The insect microbiome is a vast source of bioactive small molecules Tháng Hai 27, 2024Nat. Prod. Rep., 2024, Advance ArticleDOI: 10.1039/D3NP00054K, Review ArticleCarlismari Oliveira Grundmann, Juan Guzman, Andreas Vilcinskas, Mônica Tallarico PupoBacteria and fungi living in symbiosis with insects have been studied over the last sixty years and found to be important sources of bioactive natural products.To cite this article before page numbers are assigned, use the DOI form […]Carlismari Oliveira Grundmann
- Opportunities and challenges of RiPP-based therapeutics Tháng Hai 27, 2024Nat. Prod. Rep., 2024, Advance ArticleDOI: 10.1039/D3NP00057E, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Isabel P.-M. Pfeiffer, Maria-Paula Schröder, Silja MordhorstRibosomally synthesised and post-translationally modified peptides (RiPPs) are highly promising candidates for drug discovery and development, but challenges remain.To cite this article before page numbers are […]Isabel P.-M. Pfeiffer
- Plant peptides – redefining an area of ribosomally synthesized and post-translationally modified peptides Tháng Hai 27, 2024Nat. Prod. Rep., 2024, Advance ArticleDOI: 10.1039/D3NP00042G, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Jonathan R. Chekan, Lisa S. Mydy, Michael A. Pasquale, Roland D. KerstenPlant peptide natural products are ribosomally synthesized and post-translationally modified peptides (RiPPs). We review structure, biosynthesis, and bioactivity of plant RiPPs […]Jonathan R. Chekan
- Recent advances in discovery and biosynthesis of natural products from myxobacteria: an overview from 2017 to 2023 Tháng Hai 23, 2024Nat. Prod. Rep., 2024, Advance ArticleDOI: 10.1039/D3NP00062A, Review ArticleChao-Yi Wang, Jia-Qi Hu, De-Gao Wang, Yue-Zhong Li, Changsheng WuThis review presents a comprehensive overview of recent advances in the discovery methodologies, new structures, bioactivities, and unique biosynthetic logics of myxobacterial natural products reported from January 2017 to November 2023.To cite this article before page numbers are […]Chao-Yi Wang
- Connecting metabolome and phenotype: recent advances in functional metabolomics tools for the identification of bioactive natural products Tháng Hai 14, 2024Nat. Prod. Rep., 2024, Advance ArticleDOI: 10.1039/D3NP00050H, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Giovanni Andrea Vitale, Christian Geibel, Vidit Minda, Mingxun Wang, Allegra T. Aron, Daniel PetrasIn this review we discuss emerging functional metabolomics strategies and their potential use to reveal mechanistic insights in large-scale […]Giovanni Andrea Vitale
- Hot off the press Tháng Hai 6, 2024Nat. Prod. Rep., 2024, 41,157-161DOI: 10.1039/D4NP90005G, Hot off the Press ArticleRobert A. Hill, Andrew SutherlandA personal selection of 32 recent papers is presented covering various aspects of current developments in bioorganic chemistry and novel natural products such as dcalycinumine A from Daphniphyllum calycinum.The content of this RSS Feed (c) The Royal Society of ChemistryRobert A. Hill
- Controllable skeletal reorganizations in natural product synthesis Tháng Một 31, 2024Nat. Prod. Rep., 2024, 41,251-272DOI: 10.1039/D3NP00066D, Review ArticleZeliang Zhang, Xiao Qian, Yucheng Gu, Jinghan GuiThis review highlights controllable skeletal reorganization, which involves the formation, cleavage, and migration of C–C and C–heteroatom bonds, as a powerful strategy in the efficient syntheses of steroid, terpenoid and alkaloid natural products.The content of this RSS Feed (c) The Royal […]Zeliang Zhang
- Marine natural products Tháng Một 29, 2024Nat. Prod. Rep., 2024, 41,162-207DOI: 10.1039/D3NP00061C, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Anthony R. Carroll, Brent R. Copp, Tanja Grkovic, Robert A. Keyzers, Michèle R. PrinsepA comprehensive review of 1411 new MNPs and their structural diversity analysis and including the cyanobacterial metabolite lezoside.The content of […]Anthony R. Carroll
- Discovery, synthesis, activities, structure–activity relationships, and clinical development of combretastatins and analogs as anticancer drugs. A comprehensive review Tháng Mười Một 27, 2023Nat. Prod. Rep., 2024, 41,298-322DOI: 10.1039/D3NP00053B, Review ArticleSheo B. SinghThis comprehensive review describes discovery, synthesis, structure activity relationship, and anticancer activity of six series of 22 natural products as well as clinical studies of several candidates.The content of this RSS Feed (c) The Royal Society of ChemistrySheo B. Singh
- Dehydroamino acid residues in bioactive natural products Tháng Mười Một 9, 2023Nat. Prod. Rep., 2024, 41,273-297DOI: 10.1039/D3NP00041A, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Shan Wang, Kewen Wu, Ya-Jie Tang, Hai DengIn this review, we will discuss recent advances in the biosynthesis of peptidyl NPs containing unusual dhAA residues and cryptic dhAA residues. The proposed biosynthetic pathways […]Shan Wang
- Recent asymmetric synthesis of natural products bearing an α-tertiary amine moiety via temporary chirality induction strategies Tháng Mười 16, 2023Nat. Prod. Rep., 2024, 41,228-250DOI: 10.1039/D3NP00032J, Review ArticleHongjun Jeon, Jae Hyun Kim, Sanghee KimThis review highlights recent advances in the asymmetric synthesis of α-tertiary amine natural products via temporary chirality induction methods: Seebach's self-regeneration of stereocenters, C-to-N-to-C chirality transfer, and memory of chirality.The content of this RSS Feed (c) The Royal Society of ChemistryHongjun Jeon
- Recent advances in oxidative phenol coupling for the total synthesis of natural products Tháng Sáu 8, 2023Nat. Prod. Rep., 2024, 41,208-227DOI: 10.1039/D3NP00009E, Review ArticleMatthew C. Carson, Marisa C. KozlowskiThis review highlights modern uses of oxidative phenol coupling in the total synthesis of natural products, spanning catalytic, electrochemical, stoichiometric and enzymatic approaches.The content of this RSS Feed (c) The Royal Society of ChemistryMatthew C. Carson
- Bacillus subtilis as a host for natural product discovery and engineering of biosynthetic gene clusters Tháng Ba 11, 2024