RSC – Org. Biomol. Chem. latest articles- Photoinduced borylation of N-tosylhydrazones and application into the drug derivation Tháng Hai 20, 2025Org. Biomol. Chem., 2025, Accepted ManuscriptDOI: 10.1039/D5OB00024F, PaperWeijie Wang, Qingguang Zhang, Mengmeng Guo, Miaomiao Zhuo, Weidong Zhang, Qun Wang, Yu ZhangDirect conversion of N-tosylhydrazones by photoinduced represents a novel and highly desirable transformation. Herein, we reported a mild strategy to access the borylated compounds from aldehydes-derived N-tosylhydrazones, that neither a...The content of this RSS Feed […]Weijie Wang
- Flexible and Rigid “Chirally Distorted” -Systems: Binaphthyl Conjugates as Organic CPL-Active Chromophores Tháng Hai 19, 2025Org. Biomol. Chem., 2025, Accepted ManuscriptDOI: 10.1039/D5OB00086F, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Giovanni Preda, Elisa Maria Ciccarello, Alessio Bianchi, Francesco Zinna, Chiara Botta, Lorenzo Di Bari, Dario PasiniThe inclusion of high performance dyes into chiral -conjugated systems is an effective strategy to activate significant chiroptical […]Giovanni Preda
- New Synthetic Approaches for the Construction of Difluoromethylated Architectures Tháng Hai 19, 2025Org. Biomol. Chem., 2025, Accepted ManuscriptDOI: 10.1039/D4OB02000F, Review ArticleZhou Sun, Xue-Song Zhang, Shao-Wei Bian, Chun Zhang, Ya-Ping Han, Yong-Min LiangFluorinated compounds occupy a crucial position in the field of agrochemicals, pharmaceuticals, and material science because of their irreplaceable lipophilicity, permeability, and metabolic stability. Among all such appealing fluorine-containing functional...The content of this RSS Feed (c) […]Zhou Sun
- Copper-catalyzed enantioselective propargylic [3 + 2] cycloaddition: access to oxygen heterocycles featuring a CF3-substituted quaternary stereocenter Tháng Hai 19, 2025Org. Biomol. Chem., 2025, Advance ArticleDOI: 10.1039/D4OB02043J, PaperShweta Rohilla, Zahid Ahmad Khan, Vinod K. SinghAn enantioselective Cu(I)-catalyzed propargylic [3 + 2] cycloaddition reaction for the synthesis of optically active oxygen heterocycles bearing CF3-substituted quaternary stereocenters has been realized.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of […]Shweta Rohilla
- C–H amination of enolizable and nonenolizable ketones Tháng Hai 19, 2025Org. Biomol. Chem., 2025, Accepted ManuscriptDOI: 10.1039/D5OB00009B, Communication Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Oksana Holovko-Kamoshenkova , Zdeněk Tošner, Ivana Císařová, Radim HrdinaWe present a method for the amination of enolizable and non-enolizable ketones in the alfa (or beta) position to the carbonyl group. This approach is […]Oksana Holovko-Kamoshenkova
- Photoredox Nickel-Catalyzed Radical Cyclization of N-Arylacrylamides with Alkyl Bromides Tháng Hai 19, 2025Org. Biomol. Chem., 2025, Accepted ManuscriptDOI: 10.1039/D5OB00078E, PaperYan-Ling Liu, Liu-Shuo Shi, Xian-Chen He, Jie Gao, Ke-Rong Li, Haoyue Xiang, Kai Chen, Hua Yang3,3-Disubstituted oxindoles constitute a significant class of biologically active molecules, often found in a wide range of bioactive compounds. In this work, we present a photoredox nickel-catalyzed intermolecular cyclization between...The content of this […]Yan-Ling Liu
- Overexpression of a pathway-specific transcriptional factor CicD leads to the discovery of new phytotoxins in Aspergillus nidulans Tháng Hai 18, 2025Org. Biomol. Chem., 2025, Advance ArticleDOI: 10.1039/D4OB02051K, PaperXiaolin Liu, Jinda Hou, Lang Wang, Jing Yu, Xuewen Hou, Luning Zhou, Falei Zhang, Qian Che, Tianjiao Zhu, Dehai Li, Guojian ZhangA NRPKS gene cluster cic in Aspergillus nidulans was activated by overexpression of the pathway-specific transcriptional factor CicD.To cite this article before page numbers are assigned, use […]Xiaolin Liu
- DFT Study on Rh(II)/Guanidine-Catalyzed Asymmetric N-H bond Insertion of Benzophenone Imine Tháng Hai 18, 2025Org. Biomol. Chem., 2025, Accepted ManuscriptDOI: 10.1039/D5OB00001G, PaperJiaying Xu, Qi Wei, Changwei Hu, Zhishan SuThe enantioselective carbene insertion into the N-H bond of N-sp²-hybridized imines has proven to be an efficient method for synthesizing optically active N-unprotected amino acids. In this work, the mechanism...The content of this RSS Feed (c) The Royal Society of ChemistryJiaying Xu
- Reagent-Assisted Regio-Divergent Cyclization Synthesis of Pyrazole Tháng Hai 18, 2025Org. Biomol. Chem., 2025, Accepted ManuscriptDOI: 10.1039/D5OB00030K, CommunicationMengdi Pang, Ali Ramazani, Zhengguo Zhang, Guoying ZhangThe present study reveals a practical one-pot base-promoted regio-divergent cyclization of hydrazines with alkynyl silane under mild conditions, facilitating the synthesis of diverse silicone-substituted pyrazoles and functionalized pyrazoles in great...The content of this RSS Feed (c) The Royal Society of ChemistryMengdi Pang
- Foldameric receptors with domain-swapping cavities capable of selectively binding and transporting monosaccharides Tháng Hai 17, 2025Org. Biomol. Chem., 2025, Advance ArticleDOI: 10.1039/D4OB02061H, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Geunmoo Song, Seungwon Lee, Kyu-Sung JeongFoldameric receptors selectively bind and transport monosaccharide guests by forming dimeric complexes.To cite this article before page numbers are assigned, use the DOI form of citation above.The content […]Geunmoo Song
- Efficient Hydrosilylation of Carbonyls by Zinc Alkyl Complexes Supported by Flexible Amidophosphinochalcogenide Ligands Tháng Hai 17, 2025Org. Biomol. Chem., 2025, Accepted ManuscriptDOI: 10.1039/D5OB00004A, PaperKulsum Bano, Ravi Kumar, Archana Jain, Tarun K. PandaIn this report, we describe the synthesis and structural characterization of two zinc alkyl complexes supported by anionic PN-morpholine ligand moieties with the general formula of [к2-{Ph2P(X)N-(CH2)2N(CH2CH2)2O}Zn(C2H5)]2 [X = Se...The content of this RSS Feed (c) The Royal Society of […]Kulsum Bano
- Reusable cobalt-copper catalyzed cross-coupling of (hetero)aryl halides with primary amides under air: investigating a new Co0/CoII-based catalytic cycle Tháng Hai 17, 2025Org. Biomol. Chem., 2025, Accepted ManuscriptDOI: 10.1039/D5OB00178A, PaperAnay Saha, Keya Roy, Sampa Mondal, Bijay Saha, Jayabrata Sumar, Sumanta Kumar Sahu, Laksmikanta AdakWe report an efficient ligand-free cobalt-copper catalyzed cross-coupling reaction of aryl halides with primary amides, and also investigate a new Co0/CoII-based catalytic cycle for this transformation. This reaction successfully couples...The content of this RSS […]Anay Saha
- Diastereoselective Three-Component 1,3-Dipolar Cycloaddition: Concise Synthesis of Functionalized Tetrahydrocarboline-fused Spirooxindoles Tháng Hai 15, 2025Org. Biomol. Chem., 2025, Accepted ManuscriptDOI: 10.1039/D4OB02099E, PaperYongchao Wang, Lihua Zheng, Rongmei Zi, Yanqin Niu, Shuyuan Yang, Donghua Hu, Jian-Wei DongA novel diastereoselective and regioselective three-component 1,3-dipolar cycloaddition for the concise synthesis of functionalized tetrahydrocarboline-containing spirooxindoles is reported. Diverse 5-(2-nitroaryl)-2,4-dienones were ingeniously employed as dipolarophile of 1,3-dipolar cycloaddition, and affording...The content of this RSS Feed […]Yongchao Wang
- PIDA Mediated Oxidative [3+1+1] Annulation of aryl methyl ketone; A Facile Approach for the Chemoselective Synthesis of 5-substituted Oxazoles Tháng Hai 15, 2025Org. Biomol. Chem., 2025, Accepted ManuscriptDOI: 10.1039/D4OB01427H, PaperJagadeesh Prasad, Mohankumar DevarajuWe have developed a simple and efficient protocol for the chemoselective synthesis of 5-substituted oxazoles via [3+1+1] oxidative annulation of substituted acetophenones with NH4OAc and DMSO using PIDA as an...The content of this RSS Feed (c) The Royal Society of ChemistryJagadeesh Prasad
- Chiral 3,3′-diaroyl BINOL phosphoric acids: Syntheses, photophysical, electrochemical studies and their utility in asymmetric catalysis Tháng Hai 15, 2025Org. Biomol. Chem., 2025, Accepted ManuscriptDOI: 10.1039/D4OB02097A, PaperC. R. Ramanathan, Muthupandi Karthick, Someshwar Nagamalla, Mariappan Chinnasamy Ramaraj, Ramasubbu AlagunambiAn efficient synthesis of the enantiomerically pure 3,3′-diaroyl BINOLs is accomplished through chemoselective Weinreb ketone synthesis from Weinreb amide derivative of chiral BINOL-3,3ʹ-dicarboxylic acid using Grignard reagent. This protocol facilitated...The content of this RSS Feed (c) The […]C. R. Ramanathan
- Small far-red cationic benzoquinone diimine dyes Tháng Hai 14, 2025Org. Biomol. Chem., 2025, Advance ArticleDOI: 10.1039/D5OB00082C, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Tatiana Munteanu, Carmelo Naim, Gabriel Canard, Denis Jacquemin, Olivier Siri, Simon PascalTwo compact far-red cationic benzoquinone diimine dyes were synthesized, having molecular weights lower than 400 or 300 Da and featuring light absorption […]Tatiana Munteanu
- Recent advancements in metal-free C–C bond formation via C–H bond functionalization Tháng Hai 14, 2025Org. Biomol. Chem., 2025, Advance ArticleDOI: 10.1039/D4OB01733A, Review ArticleAnkita Sikder, Jhimli SenguptaThis review delves into the peroxides or visible light induced metal-free C–H bond cleavage to accomplish the C(sp/sp2/sp3)–H alkylation, alkenylation, arylation, carbonylation, carbamoylation, alkynylation and cyanation.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this […]Ankita Sikder
- Organobase-catalyzed Efficient Synthesis of 4-Acyl-5-Aryl Tri-substituted Triazole Linked N-Glycosides as Glycohybrids Tháng Hai 14, 2025Org. Biomol. Chem., 2025, Accepted ManuscriptDOI: 10.1039/D4OB01971G, PaperYogesh Yadav, Kavita Singh, Rajdeep Tyagi, Ram SagarHerein, we reported a highly efficient organobase-catalyzed method for the synthesis of fully decorated chirally enriched 4-acyl-5-aryl-trisubstituted-1,2,3-triazole-linked N-glycosides molecular scaffolds as glycohybrids. The process involves a base-catalysed click reaction, where...The content of this RSS Feed (c) The Royal Society of ChemistryYogesh Yadav
- Hetero-Diels–Alder reactions of (isobenzo)furans Tháng Hai 14, 2025Org. Biomol. Chem., 2025, Advance ArticleDOI: 10.1039/D5OB00050E, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Christopher J. DeAngelis, Christopher G. NewtonHerein we comprehensively review hetero-Diels–Alder reactions of (isobenzo)furans and their applications, including the synthesis of heteroaromatics, polymers, and natural products.To cite this article before page numbers are […]Christopher J. DeAngelis
- Visible-light-mediated radical difunctionalization of alkenes with aromatic aldehydes Tháng Hai 13, 2025Org. Biomol. Chem., 2025, Advance ArticleDOI: 10.1039/D4OB02090A, CommunicationZhenhua Xu, Tao Geng, Jun Du, Youpeng Zuo, Xiaoxiao Hu, Lin Liu, Zhiqiang Shi, Huawen HuangHerein, we report a novel synthetic method for α-acylalkyl glutarate derivatives through visible-light-induced photoredox cascade coupling of aromatic aldehydes with acrylates under mild conditions.To cite this article before page numbers are assigned, use […]Zhenhua Xu
- Photoinduced borylation of N-tosylhydrazones and application into the drug derivation Tháng Hai 20, 2025
