RSC – Org. Chem. Front. latest articles- [2.2]Paracyclophane–Dicyanorhodanine Conjugates as Planar Chiral Molecular Photoswitches Tháng 10 28, 2025Org. Chem. Front., 2026, Accepted ManuscriptDOI: 10.1039/D5QO01401H, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Parag Das, Cole D Stearns, Ion Ghiviriga, Lukasz Dobrzycki, Ronald K Castellano(Chir)optical molecular photoswitches have garnered significant attention for their applications in asymmetric synthesis, supramolecular chemistry, and the materials sciences. The planar […]Parag Das
- Cobalt-catalyzed Cross-Electrophile Coupling of Aryl Bromides and Linear Secondary Alkyl Bromides Tháng 10 23, 2025Org. Chem. Front., 2025, Accepted ManuscriptDOI: 10.1039/D5QO01310K, Research ArticleRuobin Wang, Qiang Hu, JUN ZHUCross-electrophile coupling (XEC) of alkyl halides and aryl halides represents a straightforward approach for the construction of the important C(sp³)-C(aryl) motif. While nickel-catalyzed such transformations are broadly investigated, the corresponding...The content of this RSS Feed (c) The Royal Society of ChemistryRuobin Wang
- Bis-Guanidinate Magnesium Amide-Catalyzed Hydroboration of Nitriles and Isocyanides via a Non-Hydride Pathway Tháng 10 23, 2025Org. Chem. Front., 2025, Accepted ManuscriptDOI: 10.1039/D5QO01184A, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Sayantan Mukhopadhyay, Smrutirani Padhan, Anubhab Das, Sharanappa NembennaThe bis-guanidinate amido magnesium (II) compound [LMgN(SiMe3)2; L = {(ArHN)(ArN)-C=N−C=(NAr)(NHAr); Ar = 2,6-Et2-C6H3] (Mg-1) has been employed as a pre-catalyst for the dihydroboration of nitriles, […]Sayantan Mukhopadhyay
- cis-Diphosphine Ethene Ligands Enable Ni-Catalyzed Amination of Aryl Chlorides Tháng 10 22, 2025Org. Chem. Front., 2025, Accepted ManuscriptDOI: 10.1039/D5QO01105A, Research ArticleGuizhi Zhai, Xulu Lv, Xiaoli Li, Yalong Li, Xiaofen Wang, Fengqian Zhao, Junliang WuA class of cis-diphosphine ethene ligands has been designed for the Ni-catalyzed C-N coupling reaction of aryl chlorides. Rigid structure, large steric hindrance and easily adjustable electronic effects are the...The content of this RSS […]Guizhi Zhai
- Transition Metal-Free Transfer of Iodoarenes by Organohypervalent Iodine Compounds. Tháng 10 22, 2025Org. Chem. Front., 2025, Accepted ManuscriptDOI: 10.1039/D5QO01262G, Review ArticleIshita Neogi, Simi Achankunju, Gourab Mohanty, Keshaba Nanda ParidaIodoarenes are important precursors used for the synthesis of compounds with C-C and C-heteroatom bonds; and are accessed either by arene iodination or by multistep functional group transformations, for instance,...The content of this RSS Feed (c) The Royal Society […]Ishita Neogi
- Photoredox-catalyzed three-component radical coupling of potassium alkyltrifluoroborates, DABSO and polyfluoroarenes Tháng 10 22, 2025Org. Chem. Front., 2025, Advance ArticleDOI: 10.1039/D5QO01163A, Research ArticleYunliang Guo, Jiuli Xia, Kaixuan Chen, Kehan Jiao, Ying Dong, Guangfan Zheng, Jiao Qu, Jiaqiong Sun, Tao Xiong, Qian ZhangVisible light-driven three-component coupling of RBF4K, DABSO, and polyfluoroarenes through radical–polar crossover mechanisms provides a modular platform for synthesis of polyfluoroarylsulfones.To cite this article before page numbers are […]Yunliang Guo
- Regioselective α-alkylation of benzo-fused cyclic amines via organic photoredox catalysis Tháng 10 21, 2025Org. Chem. Front., 2025, Advance ArticleDOI: 10.1039/D5QO01322D, Research ArticleZiwei Xia, Richang Wen, Chuang Lei, Lelin Zhou, Fuhong Xiao, Jinhui Cai, Guo-Jun Deng, Ya ChenAn organophotoredox catalytic method has been developed for the selective α-alkylation of benzo-fused cyclic amines with alkenes.To cite this article before page numbers are assigned, use the DOI form of citation above.The […]Ziwei Xia
- Molecular editing of 3-hydroxyphenyl oxindole derivatives via formal O-insertion and N-insertion: synthesis of dioxolane spirooxindoles and quinoxalin-2(1H)-ones Tháng 10 21, 2025Org. Chem. Front., 2025, Advance ArticleDOI: 10.1039/D5QO01334H, Research ArticleYao-Bin Shen, Jia-Wei Li, Peng Wang, Houchen Wang, Tiesheng Shi, Fangzhi Hu, Shuai-Shuai LiMolecular editing of 3-hydroxyphenyl oxindole derivatives via formal O-insertion and N-insertion has been developed for synthesis of dioxolane spirooxindoles and quinoxalin-2(1H)-ones.To cite this article before page numbers are assigned, use the DOI form of […]Yao-Bin Shen
- Synthesis of chiral spiro-heterocyclic azides via asymmetric [4 + 2]-cycloaddition of conjugated vinyl azides Tháng 10 20, 2025Org. Chem. Front., 2025, Advance ArticleDOI: 10.1039/D5QO01290B, Research ArticleYican Lu, Yinhe Qu, Bingqian Yang, Hailong Zhang, Weidi Cao, Xiaoming FengSynthesis of chiral spiro-heterocyclic azides via asymmetric [4 + 2]-cycloaddition of conjugated vinyl azides with aurones and (E)-alkenyloxindoles mediated by chiral N,N′-dioxide/metal complexes.To cite this article before page numbers are assigned, use the DOI form of […]Yican Lu
- Controllable synthesis of N–H or N-Me C7-substituted indazoles via a cascade reaction of α-diazo esters with aryne precursors Tháng 10 20, 2025Org. Chem. Front., 2025, Advance ArticleDOI: 10.1039/D5QO01181G, Research ArticleJing-Yi Fan, Qiang Wang, Si-Rui Jia, Yu-Xuan Zhang, Ming-Chuan Wang, Wan-Xuan Zhang, Linxing Zhang, Liang-Qiu Lu, Bin-Jie LiA [3 + 2] cycloaddition reaction utilizing cyclic diaryl λ3-bromanes and α-diazo esters to deliver either N–H or N-Me indazoles in a controllable manner is reported. DFT calculations explain the […]Jing-Yi Fan
- Nickel-catalyzed C(sp2)–H bond aminoalkylation of alkenes and arenes for the synthesis of δ-amino acid derivatives Tháng 10 20, 2025Org. Chem. Front., 2025, Advance ArticleDOI: 10.1039/D5QO01273B, Research ArticleJie-Sheng Tian, Rui-Qi Li, Duan-Yang Liu, Jie Tan, Yong-Xin Yang, Teck-Peng LohEfficient Ni-catalyzed C(sp2)-H aminoalkylation enables chiral amine synthesis with facile operation, accessible building blocks, and retained stereochemistry, advancing drug late-stage diversification.To cite this article before page numbers are assigned, use the DOI form of citation above.The […]Jie-Sheng Tian
- Pd-catalysed flow Tsuji–Trost allylation of phenols: continuous-flow, extraction-free synthesis of esmolol via allylation, epoxidation, and aminolysis Tháng 10 20, 2025Org. Chem. Front., 2025, Advance ArticleDOI: 10.1039/D5QO01336D, Research ArticleKwihwan Kobayashi, Maiko Yamashita, Takenori Kimura, Yoshihiro Kon, Takuya Nakashima, Shun-ya Onozawa, Shū KobayashiA Tsuji–Trost allylation for phenols using a heterogeneous Pd catalyst and allyl methyl carbonate, eliminating the need for halide-based reagents and bases, is reported. Through the integrated continuous-flow process, esmolol can be synthesized.To cite […]Kwihwan Kobayashi
- Visible Light Induced Cross-Dehydrogenative Coupling of N-Heterocyclic Compounds: Green and Efficient Synthetic Strategies Tháng 10 20, 2025Org. Chem. Front., 2025, Accepted ManuscriptDOI: 10.1039/D5QO01346A, Review ArticleDivyani P. Patel, Vishwa K. Patel, Satish Kumar SinghCross-dehydrogenative coupling (CDC), which directly modifies C–H bonds, is a powerful tool in modern organic synthesis. It saves atoms and steps while making it easier to obtain a wide variety...The content of this RSS Feed (c) The Royal Society […]Divyani P. Patel
- Are N-heterocyclic carbene radical cations relevant intermediates in radical transformations? Tháng 10 19, 2025Org. Chem. Front., 2025, Advance ArticleDOI: 10.1039/D5QO01285F, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Preslav Smits, Ludivine Delfau, Sheima Bougoffa, Florian Molton, Jacques Pecaut, Julie Broggi, Eder Tomás-Mendivil, David MartinIs there an oxidized version of the Wanzlick equilibrium?To cite this article before page numbers are assigned, […]Preslav Smits
- Electroreductive thiocarboxylation of alkenes with cyclosulfonium salts and CO2: access to thioether acids Tháng 10 19, 2025Org. Chem. Front., 2025, Advance ArticleDOI: 10.1039/D5QO01313E, Research ArticleYong-Fei Huang, Li-Jie Wang, Mu-Jiang Luo, Chaozhihui Cheng, Qiang XiaoThis work establishes a mild, ambient approach for thiocarboxylation of alkenes, providing a sustainable platform for green chemistry by avoiding the use of transition metal catalysts or external reductants.To cite this article before page numbers are assigned, use […]Yong-Fei Huang
- Copper-catalyzed radical aminocyanation of allenes Tháng 10 17, 2025Org. Chem. Front., 2025, Advance ArticleDOI: 10.1039/D5QO01254F, Research ArticleSheng Du, Wei-Qian Fan, Jun-Qi Liu, Ying Tong, Dong-Qing Yang, Youren Dong, Hailin Cai, Zhengyu Deng, Tianbo Liu, Wen-Ting WeiWe report a copper-catalyzed three-component aminocyanation of allenes using N-halobenzenesulfonimides and trimethylsilyl cyanide, achieving simultaneous installation of amine and cyano groups with high regioselectivity.To cite this article before […]Sheng Du
- Photoredox-catalyzed multicomponent 1,2-difunctionalization of activated alkenes with silyl enol ethers and oxime esters Tháng 10 16, 2025Org. Chem. Front., 2025, Advance ArticleDOI: 10.1039/D5QO01314C, Research ArticleMing-Xian Zhang, Yu Bao, Tao Wang, Shenghu Yan, Yue Zhang, Jia-Yin WangWe report a photoredox-catalyzed multicomponent 1,2-difunctionalization reaction of electron-deficient alkenes, employing silyl enol ethers along with either cycloketone oxime esters or indanone oxime esters.To cite this article before page numbers are assigned, use the DOI form […]Ming-Xian Zhang
- Photocat alytic Synthesis and Closed-Loop Recycling of Poly(semi-aromatic 1,2-ethanediol)s Tháng 10 16, 2025Org. Chem. Front., 2025, Accepted ManuscriptDOI: 10.1039/D5QO01075F, Research ArticleYi-Ming Chen, Yu Liu, Yong-Ze Chen, Yan-Biao KangThe strategy of closed-loop recycling of plastic waste has been recognized as an indispensable access to solving environment problems and relieving resource scarcity. However, the design of new monomer-to-polymer-to-monomer recycling...The content of this RSS Feed (c) The Royal Society of […]Yi-Ming Chen
- Helicoselective assembly of 2-pyranone-helicenoids via NHC-catalyzed [3 + 3] annulation Tháng 10 16, 2025Org. Chem. Front., 2025, Advance ArticleDOI: 10.1039/D5QO01328C, Research ArticleJiahui Zhou, Shujie Ji, Zhipeng Li, Yuhan Liu, Yani Li, Jian WangAn NHC-catalyzed helicoselective [3 + 3] annulation approach is reported for the assembly of chiral 2-pyranone fused helicenoids with good yields and high to excellent enantioselectivities.To cite this article before page numbers are assigned, use the […]Jiahui Zhou
- Masked formylation of activated aromatics via dithianes and a mild, sustainable cleavage protocol Tháng 10 16, 2025Org. Chem. Front., 2025, Advance ArticleDOI: 10.1039/D5QO01300C, Research ArticleJulia Urbiña-Alvarez, Daniela Torres-Ruiz, Camilo Mahecha-Mahecha, Gabriel Hernandez-Abdallah, Mario Macías, Diego Gamba-SánchezMasked formylation using dithiane oxide activated by oxalyl chloride via a thionium ion. It enables efficient substitution in electron-rich arenes and mild dithiane cleavage to aldehydes, offering a simple, versatile alternative to classical methods.To cite this […]Julia Urbiña-Alvarez
- [2.2]Paracyclophane–Dicyanorhodanine Conjugates as Planar Chiral Molecular Photoswitches Tháng 10 28, 2025
