RSC – Org. Chem. Front. latest articles- Iridium-catalyzed intramolecular allylic substitution reaction: efficiently enantioselective synthesis of 1,3,4-oxadiazine, oxazo-lines and 1,3-oxazine derivatives Tháng 1 20, 2026Org. Chem. Front., 2026, Accepted ManuscriptDOI: 10.1039/D5QO01683E, Research ArticleXiyu Li, Fang Hu, Yinsheng Qi, Shichuan Wang, Xin-Ping HuiAn efficient Ir-catalyzed enantioselective intramolecular allylic substitution reaction for the synthesis of five- and six-membered N,O-heterocycle compounds has been achieved. This method offers a facile, straightforward access to a diverse...The content of this RSS Feed (c) The Royal […]Xiyu Li
- Ir-catalyzed asymmetric transfer hydrogenation of racemic quinolinyl-substituted tertiary alcohols Tháng 1 20, 2026Org. Chem. Front., 2026, Accepted ManuscriptDOI: 10.1039/D5QO01723H, Research ArticleZhuang Haokun, Huizhen Zhang, Mangang Zhang, Zhiwen Nie, Qin YinWe report herein a highly efficient stereodivergent reaction on racemic quinolinyl-substituted tertiary alcohols via Ir-catalyzed asymmetric transfer hydrogenation, which affords structurally unique chiral 1,2,3,4-tetrahydroquinolines bearing both endo- and exocyclic chirality....The content of this RSS Feed (c) The Royal […]Zhuang Haokun
- Chiral π-Extended Diindenoperylenes Featuring Dithia[7]helicenes Tháng 1 20, 2026Org. Chem. Front., 2026, Accepted ManuscriptDOI: 10.1039/D5QO01701G, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Georg Berger, Jan Borstelmann, Frank - Rominger, Milan KivalaHelically chiral π-expanded diindenoperylenes were synthesized and their chiroptical properties characterized. The enantiopure synthesis of the perylene framework was achieved by two-fold Yamamoto coupling […]Georg Berger
- Synthesis of azadehydrobenzoannulenes exhibiting exceptional luminescence performance Tháng 1 19, 2026Org. Chem. Front., 2026, Accepted ManuscriptDOI: 10.1039/D5QO01657F, Research ArticleJinling Zhang, Huabi Xie, Yu Zuo, Ningwen Sun, Chengye Yuan, Hongxing Jia, Jinjin Ding, Qiang Huang, Peng XuHerein, a family of cyclic electron donor-acceptor structures was synthesized and characterized, in which carbazole was used as the donor integrated into dehydrobenzoannulene (DBA). Subsequent solvent-dependent fluorescence spectra revealed that...The […]Jinling Zhang
- Ligand-Controlled Switchable Nickel-Catalyzed Coupling of Nitriles with Aryl Triflates: Divergent Synthesis of Ketones and Diarylmethanes Tháng 1 16, 2026Org. Chem. Front., 2026, Accepted ManuscriptDOI: 10.1039/D5QO01644D, Research ArticleXianmao Liu, Yaqi Chen, Qian Ni, Xueyu Liu, Zhi-Juan He, Yuanhong MaA ligand-controlled switchable nickel-catalyzed coupling reaction between nitriles and aryl triflates has been developed, enabling the divergent synthesis of two privileged classes of molecules—ketones and diarylmethanes—from identical starting materials. The...The content of this RSS Feed (c) […]Xianmao Liu
- Visible-Light-Driven Electrophilic Chalcogen Species: Integration of Sustainable Synthesis, Green Metrics, and Computational Discovery of Antioxidants Tháng 1 15, 2026Org. Chem. Front., 2026, Accepted ManuscriptDOI: 10.1039/D5QO01286D, Research ArticleFilipe Teodoro Coelho, Leonardo Victor Espíndola Guimaraes, Camila Ebersol, Pamella da Costa, Larissa Garcia Velasco, Cristiani Bortolatto, Wendell Karlos Tomazelli Coltro, Luciano Morais Lião, Felipe Lange Coelho, Jose NetoThe emergence of green chemistry principles has driven researchers to develop more sustainable methods for organic synthesis. However, despite […]Filipe Teodoro Coelho
- Rh(III)-catalyzed regioselective C6-arylation of 2-pyridones with diazonaphthalen-2(1H)-ones along with directing group migration Tháng 1 14, 2026Org. Chem. Front., 2026, Advance ArticleDOI: 10.1039/D5QO01563D, Research ArticleYuanshuang Xu, Shuya Zhang, Yujing Xiao, Xinying Zhang, Xuesen FanHerein, we describe a Rh(III)-catalyzed cascade reaction between 2-pyridones and diazonaphthalen-2(1H)-ones, providing an efficient and convenient synthetic route to 6-(2-(pyridin-2-yloxy)naphthalen-1-yl)pyridin-2(1H)-ones.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this […]Yuanshuang Xu
- Benzophenone-catalyzed alkenylative pyridylation of vinylarenes with alkenylboronic esters Tháng 1 13, 2026Org. Chem. Front., 2026, Advance ArticleDOI: 10.1039/D5QO01578B, Research ArticleYuhui Ying, Zixiang Li, Bin LiuWe present a metal-free and gentle three-component reaction for the synthesis of alkenes using benzophenone as a photocatalyst in combination with alkenylboronic esters.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS […]Yuhui Ying
- Outer-sphere reductive elimination as the enantio-determining step in IrIII/NiII metallaphotoredox-catalyzed α-(hetero)aryl amination: a DFT study Tháng 1 13, 2026Org. Chem. Front., 2026, Advance ArticleDOI: 10.1039/D5QO01726B, Research ArticleYa-Bin Jiang, Wei Guan, Yu-Jie LiangOuter-sphere reductive elimination as the enantio-determining step in IrIII/NiII metallaphotoredox-catalyzed α-(hetero)aryl amination has been theoretically disclosed.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of ChemistryYa-Bin Jiang
- Biomimetic Total Synthesis of Ten Securinega Alkaloids Tháng 1 13, 2026Org. Chem. Front., 2026, Accepted ManuscriptDOI: 10.1039/D5QO01704A, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Lachlan J. N. Waddell, Zhouqian Jiang, Gideon Grogan, Benjamin Robert Lichman, William Paul UnsworthThe Securinega alkaloids are a diverse family of polycyclic alkaloids with broad biological importance. In this study, a formal […]Lachlan J. N. Waddell
- Crab-shape C2-symmetric chiral Tpy-bisulidine ligands: design, synthesis and application in diversity-oriented asymmetric catalysis Tháng 1 13, 2026Org. Chem. Front., 2026, Accepted ManuscriptDOI: 10.1039/D5QO01530H, Research ArticleLi Wuwu, Hong-Xing Cen, Di-Cheng Pan, Lin-Lu Liu, Li-Jun Peng, Zi-Hong Hu, Xiong-Li LiuTerpyridine-type ligands were renowned for their rich coordination with various metal ions. However, their high cost and tedious preparation methods limit their further application in asymmetric catalysis. Herein, we prepared...The content of this RSS […]Li Wuwu
- Modular assembly of conformationally dynamic dinaphthocycloocta-1,5-dienes Tháng 1 13, 2026Org. Chem. Front., 2026, Advance ArticleDOI: 10.1039/D5QO01621E, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Michel Große, Christopher M. Leonhardt, Hermann A. WegnerA Lewis acid-catalyzed inverse electron-demand Diels–Alder sequence enables the stepwise annulation of naphthalene units onto a cyclooctadiene scaffold, affording conformationally dynamic fused polycycles.To cite this […]Michel Große
- Lewis acid-catalyzed cascade via intercepted Meyer-Schuster O-allenylation and [3,3]-sigmatropic rearrangement: Divergent synthesis of 2-alkenylanilines and indoles Tháng 1 13, 2026Org. Chem. Front., 2026, Accepted ManuscriptDOI: 10.1039/D5QO01615K, Research ArticleWen-Bin Xu, Li-Na Yang, Yang-Shuang Wang, Yu Zhang, Xiao-Han Qiu, Yu-Ning Gao, Ming Bian, Cun-Feng Song, Hui-Yu Chen, Zhen-Jiang LiuA Lewis acid-catalyzed cascade reaction has been developed for the synthesis of 2-alkenylaniline derivatives bearing an enone moiety. This method utilizes readily available N-aryl hydroxylamines and propargylic alcohols […]Wen-Bin Xu
- Substrate-controlled mechanistic switch between protodemetalation and oxidative addition in Rh-catalyzed carbometalation: a DFT study Tháng 1 13, 2026Org. Chem. Front., 2026, Advance ArticleDOI: 10.1039/D5QO01672J, Research ArticleChunhui Shan, Hong Chen, Xiang Zhang, Xiaoling LuoThis DFT study reveals substrate-dependent mechanisms in Rh(I)-catalyzed carbometalation: dihydropyridines undergo insertion/protodemetalation, while dihydroquinolines favor oxidative addition, dictating enantioselectivity at different steps.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this […]Chunhui Shan
- Base-Promoted Synthesis of β-Keto Sulfone with N-Acyl Pyrroles and Allyl Sulfones Tháng 1 13, 2026Org. Chem. Front., 2026, Accepted ManuscriptDOI: 10.1039/D5QO01410G, Research ArticleJianwei Wang, Fangjie Xu, Jie LiAn efficient method has been developed for the direct transformation of allyl sulfone to β-keto sulfones by their reaction with N-acyl pyrroles under transition metal-free conditions. Simply combining equivalent N-acyl...The content of this RSS Feed (c) The Royal Society of ChemistryJianwei Wang
- Carbonyls as Potential Alkenyl Carbanions for Deoxygenative Cross-Coupling with Alkyl Electrophiles Tháng 1 13, 2026Org. Chem. Front., 2026, Accepted ManuscriptDOI: 10.1039/D5QO01404B, Research ArticleMei Bai, Shasha Geng, Cheng Ma, Minghui Sun, Chaoqun Shi, Yun He, Shaofei Ni, Zhang FengThe example of carbonyls as alkenyl carbanions for deoxygenative cross-coupling with alkyl electrophiles has been developed, facilitating the efficient synthesis of alkenes and enabling carbonyl 1,2-transposition alkylation. This protocol features...The content of […]Mei Bai
- Correction: Synthesis of quinoline derivatives by palladium-catalyzed isocyanide insertion/undirected C(sp2)–H functionalization/[4 + 1] cyclization reactions involving aryl isocyanide Tháng 1 12, 2026Org. Chem. Front., 2026, Advance ArticleDOI: 10.1039/D6QO90004F, Correction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Shan-Shan Liu, Yong-Jie Wu, Jiang-Nan Zheng, Zhi-Lin Ren, Shao-Jie Jiang, Jun Wu, Ke-Ji Li, Ping He, Long WangTo cite this article before page numbers are assigned, use the DOI form of citation above.The […]Shan-Shan Liu
- DMSO/Tf2O-promoted regio- and Z-stereoselective sulfonyl functionalization of terminal alkynes Tháng 1 12, 2026Org. Chem. Front., 2026, Advance ArticleDOI: 10.1039/D5QO01607J, Research ArticleYuxin Guo, Hanru Tang, Zhiyan Liu, Zhiping Wang, Long-Yong Xie, Jian WenWe report a DMSO/Tf2O-promoted regio- and Z-stereoselective sulfonyl functionalization of terminal alkynes that delivers diverse functionalized vinyl sulfones in a highly selective manner under tunable basic conditions.To cite this article before page numbers are assigned, use […]Yuxin Guo
- Metal- and additive-free ipso-benzylation of arylsilanes to access diarylmethanes Tháng 1 12, 2026Org. Chem. Front., 2026, Advance ArticleDOI: 10.1039/D5QO01554E, Research ArticleWanting Fu, Jialong Zhong, Shuang Lv, Xinyu Song, Yilin Xing, Zikun WangA metal- and additive-free ipso-benzylation of arylsilanes was developed to efficiently synthesize symmetrical and unsymmetrical diarylmethanes.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed […]Wanting Fu
- Harnessing alkaline-earth metal reactivity: mechanistic insights into alkene and alkyne functionalization via organomagnesium(II) and organobarium(II) catalysis Tháng 1 10, 2026Org. Chem. Front., 2026, Advance ArticleDOI: 10.1039/D5QO01464F, Research ArticleYumiao MaA comprehensive in silico exploration establishes fundamental understanding for alkaline-earth catalysis, proving these earth-abundant metals can function as transition-metal mimics with complementary reactivities in migratory insertion reactions.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS […]Yumiao Ma
- Iridium-catalyzed intramolecular allylic substitution reaction: efficiently enantioselective synthesis of 1,3,4-oxadiazine, oxazo-lines and 1,3-oxazine derivatives Tháng 1 20, 2026
