RSC Chemical Biology

RSC – RSC Chem. Biol. latest articles

• A novel SadP-scFv UCHT1 lectibody activates T cells and mediates lysis of Burkitt’s lymphoma cells Tháng mười một 20, 2025
  RSC Chem. Biol., 2025, Accepted ManuscriptDOI: 10.1039/D5CB00027K, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Jana Tomisch, Jonas Gräber, Olga N. Makshakova, Pavel Salavei, Francesca Rosato, Sarah Frisancho Mariscal, Annabelle Varrot, Anne Imberty, Winfried RömerAbnormal glycosylation has been long considered a hallmark of cancer progression. Carbohydrate-binding proteins, also […]
  Jana Tomisch
• Dual spatio-functional control of a fission yeast-based bioprocessor upon chemical induction Tháng mười một 17, 2025
  RSC Chem. Biol., 2025, Accepted ManuscriptDOI: 10.1039/D5CB00147A, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Stavroula Melina Sakellakou, Valerie Migeot, Laure-Elie Carloni, Elisa Martino, André Oliveira Sequeira, Terézia Morávková, Lorenzo Riccio, Sorin Melinte, Laura Maggini, Damien Hermand, Davide BonifaziNext-generation therapies are advancing beyond small molecules and proteins toward […]
  Stavroula Melina Sakellakou
• Red-Shifted D-Luciferin Analogues and their Bioluminescence Characteristics Tháng mười một 14, 2025
  RSC Chem. Biol., 2025, Accepted ManuscriptDOI: 10.1039/D5CB00287G, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Pratchaya Watthaisong, Chadaporn Kantiwiriyawanitch, Watcharapa Jitkaroon , Aisaraphon Phintha, Ittiphat Klayparn, Narin Lawan, Philaiwarong Kamutira, Daisuke Sasaki, Surawit Visitsatthawong, Somchart Maenpuen, Ruchanok Tinikul, Jeerus Sucharitakul, Ryo Nishihara, Kazuki Niwa, Yoshihiro Nakajima, Yoshihiro Ohmiya, […]
  Pratchaya Watthaisong
• From loops to caps: discriminating peptide binding to distinct G-quadruplex tetrads using 5-furyl-2′-deoxyuridine fluorescent probes Tháng mười một 10, 2025
  RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D5CB00247H, Communication Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Jack Barr, Tayler D. Prieto Otoya, Christine Cardin, Enrico CadoniSite-specific 5-furyl-2′-deoxyuridine (5FU) labels at G-quadruplex (G4) caps generate fluorescence turn-on readouts that resolve tetrad-specific binding of peptide RHAU23, enabling tetrad affinity determination on […]
  Jack Barr
• RNA-binding fluorogenic probes: G-clamp conjugated with a thiazole orange derivative for screening RNA-binding small molecules Tháng mười một 3, 2025
  RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D5CB00078E, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Ryosuke Nagasawa, Kazumitsu Onizuka, Ryohei Iwata, Kosuke Tsuzuki, Kaoru R. Komatsu, Emi Miyashita, Sayaka Dantsuji, Hirotaka Murase, Hirohide Saito, Fumi NagatsugiWe developed a novel fluorescent indicator, TO-G-clamp, by conjugating a thiazole orange derivative […]
  Ryosuke Nagasawa
• High-resolution structure of proIAPP(1–48) fibrils suggests a mechanistic pathway for diabetes-associated IAPP fibril polymorphs Tháng 10 31, 2025
  RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D5CB00228A, Communication Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Dylan Valli, Michał MajStructure of misprocessed proIAPP(1–48) shows how processing errors may bias hIAPP toward disease-relevant folds.To cite this article before page numbers are assigned, use the DOI form of citation above.The content […]
  Dylan Valli
• Application of HIV-1 viral protein R-derived-peptides as new E3 ligase-binding components of BRD4 degraders Tháng 10 29, 2025
  RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D5CB00125K, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Kohei Tsuji, Xueyuan Huang, Maho Miyamoto, Sayaka Sukegawa, Hidetomo Yokoo, Hiroaki Takeuchi, Yosuke Demizu, Hirokazu TamamuraAn HIV-1 accessory protein Vpr-derived peptide functions as an E3 ligase ligand, and this peptide-containing molecules successfully degraded […]
  Kohei Tsuji
• Investigating the utilization mechanism and kinetics of sialic acid mimetics in mammalian cell lines Tháng 10 29, 2025
  RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D5CB00193E, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Eline A. Visser, Daniël L. A. H. Hornikx, Moritz Rahm, Özden Öztürk, Venetia Psomiadou, Matteo Calzari, Celine Mennen, Sam J. Moons, Martin Jaeger, Dirk J. Lefeber, Christian Büll, Thomas J. BoltjeSialic acid mimetics […]
  Eline A. Visser
• Covalent fragment screening to inhibit the E3 ligase activity of bacterial NEL enzymes SspH1 and SspH2 Tháng 10 28, 2025
  RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D5CB00177C, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Cassandra R. Kennedy, Katherine A. McPhie, Aini Vuorinen, Jane Dudley-Fraser, Diego Esposito, Sarah Maslen, William J. McCarthy, Jonathan Pettinger, J. Mark Skehel, Jacob Bush, David House, Katrin RittingerIdentification of active site inhibitors of […]
  Cassandra R. Kennedy
• Nucleobase catalysts for the enzymatic activation of 8-oxoguanine DNA glycosylase 1 Tháng 10 28, 2025
  RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D4CB00323C, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Emily C. Hank, Nicholas D. D’Arcy-Evans, Emma Rose Scaletti, Carlos Benítez-Buelga, Olov Wallner, Florian Ortis, Kaixin Zhou, Liuzhen Meng, Alicia del Prado, Patricia Calvo, Ingrid Almlöf, Elisée Wiita, Karen Nierlin, Sara Košenina, Andreas […]
  Emily C. Hank