RSC Chemical Biology

RSC – RSC Chem. Biol. latest articles

• Engineering Regiospecific Methylation of the Pladienolides Tháng 5 7, 2025
  RSC Chem. Biol., 2025, Accepted ManuscriptDOI: 10.1039/D5CB00068H, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Emily R. Smith, Dua H. Al-Smadi, Yitao Dai, Manead Khin, Joanna E Burdette, Brendan M. Duggan, James J LaClair, Alessandra Eustaquio, Michael BurkartWell-recognized for the ability to modulate spliceosome activity, the pladienolide family […]
  Emily R. Smith
• Efficient Synthesis of O-Glycosylated amino acids Tháng 5 6, 2025
  RSC Chem. Biol., 2025, Accepted ManuscriptDOI: 10.1039/D5CB00076A, Communication Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Felicity Jane Frank, Rebecca Lawson, Tom Ewan McAllisterProtein glycosylation is one of the most abundant and complex post-translational modifications, necessitating many different approaches to fully understand the biological effects. Investigation using synthetic glycopeptides […]
  Felicity Jane Frank
• An iridium(III) monosulfur-substituted chlorotetrazine complex for cysteine conjugation, bioimaging and photoactivatable therapy Tháng 5 6, 2025
  RSC Chem. Biol., 2025, Accepted ManuscriptDOI: 10.1039/D4CB00316K, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Lili Huang, Justin Shum, Lawrence Cho-Cheung Lee, Guang-Xi Xu, Peter Kam-Keung Leung, Kenneth Kam-Wing LoPhotoactivatable systems have received considerable attention in the development of diagnostics and therapeutics due to their noninvasive nature and […]
  Lili Huang
• Exploring Sequence- and Structure-based Fitness Landscapes to Enhance Thermal Resistance and Activity of Endoglucanase II with Minimal Experimental Effort Tháng 5 4, 2025
  RSC Chem. Biol., 2025, Accepted ManuscriptDOI: 10.1039/D5CB00013K, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Atul Kumar, Alexander Illig, Nicolas de la Vega Guerra, Francisca Contreras, Mehdi D. Davari, Ulrich SchwanebergEnhancing the performance of cellulases at high temperatures is crucial for efficient biomass hydrolysis—a fundamental process in sustainable […]
  Atul Kumar
• Exploring substitution effects on the potential dominant conformations of NBF derivatives leading to functional conversion at the mu opioid receptor Tháng 5 4, 2025
  RSC Chem. Biol., 2025, Accepted ManuscriptDOI: 10.1039/D5CB00036J, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Ennian Li, Ahmed Reda, Hongguang Ma, Samuel Woodard, James Gillespie, Dana E. Selley, William Dewey, Piyusha P Pagare, Yan ZhangWe previously identified NBF (β-configuration at C6) and its 6α-counterpart as mu opioid receptor […]
  Ennian Li
• Co-delivery of antigen and adjuvant by site-specific conjugation to dendritic cell-targeted Fab fragments potentiates T cell responses Tháng 5 4, 2025
  RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D5CB00014A, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Zacharias Wijfjes, Iván Ramos Tomillero, Camille M. Le Gall, Eric A. W. van Dinther, Frederique Turlings, René Classens, Saikat Manna, Duco van Dalen, Ruud J. R. W. Peters, Kayleigh Schouren, Felix L. Fennemann, […]
  Zacharias Wijfjes
• A State of Art View: G-quadruplex-targeting for platinum complexes treatment tumors Tháng 4 28, 2025
  RSC Chem. Biol., 2025, Accepted ManuscriptDOI: 10.1039/D5CB00024F, Review Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jinrong Yang, Yu Chen, Hui ChaoCisplatin and its analogs are extensively utilized as metal-based anticancer agents in clinical settings due to their mechanism of action, which involves targeting genomic double-stranded DNA to […]
  Jinrong Yang
• Design of a stapled peptide that binds to the Ebola virus matrix protein dimer interface Tháng 4 24, 2025
  RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D5CB00048C, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Roopashi Saxena, Madison M. Wright, Benjamin M. Rathman, Ukesh Karki, Prem P. Chapagain, Juan R. Del Valle, Robert V. StahelinThe structure of the VP40 dimer interface was used to design a series of […]
  Roopashi Saxena
• Proximity-induced SuFEx increases the potency of cytosolic nucleotidase inhibitors and reveals a rare example of covalently targeted histidine Tháng 4 22, 2025
  RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D5CB00005J, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Mikolaj Chrominski, Marcin Warminski, Mateusz Kozarski, Dorota Kubacka, Joanna Panecka-Hofman, Tomasz Spiewla, Mikolaj Zmudzinski, Jacek Jemeility, Joanna KowalskaStructure-guided design of SuFEx-based inhibitor enables rapid and selective covalent targeting of cytosolic nucleotidase IIIB via […]
  Mikolaj Chrominski
• Monitoring SARS-CoV-2 Nsp13 helicase binding activity using expanded genetic code techniques Tháng 4 20, 2025
  RSC Chem. Biol., 2025, Advance ArticleDOI: 10.1039/D4CB00230J, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Eryn Lundrigan, Christine Hum, Nadine Ahmed, John Paul PezackiThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-structural protein 13 (Nsp13) helicase is a multi-functional protein that can unwind dsDNA and dsRNA in an […]
  Eryn Lundrigan