RSC – RSC Chem. Biol. latest articles
- ORP9-PH domain-based fluorescent reporters for visualizing phosphatidylinositol 4-phosphate dynamics in living cells Tháng Tư 23, 2024RSC Chem. Biol., 2024, Advance ArticleDOI: 10.1039/D3CB00232B, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Moeka Ajiki, Masaru Yoshikawa, Tomoki Miyazaki, Asami Kawasaki, Kazuhiro Aoki, Fubito Nakatsu, Shinya TsukijiNew fluorescent reporters based on the ORP9 PH domain visualize phosphatidylinositol 4-phosphate (PI4P) dynamics at multiple cellular locations with high […]Moeka Ajiki
- Reverse transcription as key step in RNA in vitro evolution with unnatural base pairs Tháng Tư 22, 2024RSC Chem. Biol., 2024, Accepted ManuscriptDOI: 10.1039/D4CB00084F, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Eva S. Hoffmann, Mareike C. De Pascali, Lukas Neu, Christof Domnick, Alice Soldà, Stephanie Kath-SchorrUnnatural base pairs (UBPs) augment the chemical diversity of artificial nucleic acids and can thus enable the generation of […]Eva S. Hoffmann
- Why pyridoxal phosphate could be a functional predecessor of thiamine pyrophosphate and speculations on a primordial metabolism Tháng Tư 17, 2024RSC Chem. Biol., 2024, Accepted ManuscriptDOI: 10.1039/D4CB00016A, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Andreas KirschningThe account attempts to substantiate the hypothesis that, from an evolutionary perspective, the coenzyme couple pyridoxal phosphate and pyridoxamine phosphate preceded the coenzyme thiamine pyrophosphate and acted as its less...The content […]Andreas Kirschning
- Ancient and modern mechanisms compete in progesterone receptor activation Tháng Tư 14, 2024RSC Chem. Biol., 2024, Advance ArticleDOI: 10.1039/D4CB00002A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Sabab Hasan Khan, Namita Dube, Nishanti Sudhakar, Olivia Fraser, Priscilla Villalona, Sean M. Braet, Stephanie Leedom, Erin R. Reilly, Jacob Sivak, Kenidee Crittenden, C. Denise OkaforThe progesterone receptor is activated by ligands utilizing […]Sabab Hasan Khan
- Reduction midpoint potential of a paradigm light–oxygen–voltage receptor and its modulation by methionine residues Tháng Tư 8, 2024RSC Chem. Biol., 2024, Advance ArticleDOI: 10.1039/D4CB00056K, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Andrés García de Fuentes, Andreas MöglichThe introduction of methionine residues into the Avena sativa phototropin 1 LOV2 domain raises the reduction midpoint of its flavin-nucleotide chromophore.To cite this article before page numbers are […]Andrés García de Fuentes
- Advances in the joint profiling technologies of 5mC and 5hmC Tháng Tư 4, 2024RSC Chem. Biol., 2024, Advance ArticleDOI: 10.1039/D4CB00034J, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Bo He, Haojun Yao, Chengqi YiOverview of the joint profiling technologies of 5mC and 5hmC.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of […]Bo He
- Prevention of amyloid β fibril deposition on the synaptic membrane in the precuneus by ganglioside nanocluster-targeting inhibitors Tháng Tư 3, 2024RSC Chem. Biol., 2024, Advance ArticleDOI: 10.1039/D4CB00038B, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Erika Miyamoto, Hideki Hayashi, Shigeo Murayama, Katsuhiko Yanagisawa, Toshinori Sato, Teruhiko MatsubaraInvestigation of synaptosomal plasma membrane-induced Aβ fibrils emphasizes the importance of specifically targeting ganglioside nanoclusters in precuneus against Alzheimer's disease.To cite this […]Erika Miyamoto
- Polyamines promote xenobiotic nucleic acid synthesis by modified thermophilic polymerase mutants Tháng Tư 3, 2024RSC Chem. Biol., 2024, Advance ArticleDOI: 10.1039/D4CB00017J, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Hidekazu Hoshino, Yuuya Kasahara, Satoshi ObikaPolyamines stimulate the synthesis of various xenobiotic nucleic acids (XNA) by modified thermophilic DNA polymerase mutants.To cite this article before page numbers are assigned, use the DOI form […]Hidekazu Hoshino
- Site-specific RNA modification via initiation of in vitro transcription reactions with m6A and isomorphic emissive adenosine analogs Tháng Ba 27, 2024RSC Chem. Biol., 2024, Advance ArticleDOI: 10.1039/D4CB00045E, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Deyuan Cong, Kfir B. Steinbuch, Ryosuke Koyama, Tyler V. Lam, Jamie Y. Lam, Yitzhak TorTranscription reactions with excess adenosine surrogates leads to 5′-end modified transcripts, which can be ligated to diverse RNAs. By […]Deyuan Cong
- Engineering cell-free systems by chemoproteomic-assisted phenotypic screening Tháng Ba 6, 2024RSC Chem. Biol., 2024, 5,372-385DOI: 10.1039/D4CB00004H, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Zarina Levitskaya, Zheng Ser, Hiromi Koh, Wang Shi Mei, Sharon Chee, Radoslaw Mikolaj Sobota, John F. GhadessyPhenotypic screening identified drugs capable of improving the yeast lysate cell-free protein synthesis (CFPS) yield. A drug target […]Zarina Levitskaya
- ORP9-PH domain-based fluorescent reporters for visualizing phosphatidylinositol 4-phosphate dynamics in living cells Tháng Tư 23, 2024